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BR9711541A - Dihidrato d de olanzapina - Google Patents

Dihidrato d de olanzapina

Info

Publication number
BR9711541A
BR9711541A BR9711541A BR9711541A BR9711541A BR 9711541 A BR9711541 A BR 9711541A BR 9711541 A BR9711541 A BR 9711541A BR 9711541 A BR9711541 A BR 9711541A BR 9711541 A BR9711541 A BR 9711541A
Authority
BR
Brazil
Prior art keywords
olanzapine dihydrate
olanzapine
dihydrate
Prior art date
Application number
BR9711541A
Other languages
English (en)
Inventor
Samuel Dean Larsen
John Richard Nicholson
Susan Marie Reutzel
Gregory Alan Stephenson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21832112&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9711541(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BR9711541A publication Critical patent/BR9711541A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/38[b, e]- or [b, f]-condensed with six-membered rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
BR9711541A 1996-09-23 1997-09-18 Dihidrato d de olanzapina BR9711541A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2648696P 1996-09-23 1996-09-23
PCT/US1997/016586 WO1998011893A1 (en) 1996-09-23 1997-09-18 Olanzapine dihydrate d

Publications (1)

Publication Number Publication Date
BR9711541A true BR9711541A (pt) 1999-08-24

Family

ID=21832112

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9711541A BR9711541A (pt) 1996-09-23 1997-09-18 Dihidrato d de olanzapina

Country Status (34)

Country Link
US (1) US6251895B1 (pt)
EP (1) EP0831097B1 (pt)
JP (1) JP2001500878A (pt)
KR (1) KR100516088B1 (pt)
CN (1) CN1146567C (pt)
AR (1) AR009801A1 (pt)
AT (1) ATE221074T1 (pt)
AU (1) AU720366B2 (pt)
BR (1) BR9711541A (pt)
CA (1) CA2266444C (pt)
CO (1) CO4900057A1 (pt)
CZ (1) CZ299247B6 (pt)
DE (1) DE69714165T2 (pt)
DK (1) DK0831097T3 (pt)
EA (1) EA001881B1 (pt)
EG (1) EG23815A (pt)
ES (1) ES2180899T3 (pt)
HU (1) HU226167B1 (pt)
ID (1) ID21924A (pt)
IL (1) IL128956A0 (pt)
MY (1) MY125467A (pt)
NO (1) NO323979B1 (pt)
NZ (1) NZ334346A (pt)
PE (1) PE110298A1 (pt)
PL (1) PL194074B1 (pt)
PT (1) PT831097E (pt)
RS (1) RS49597B (pt)
SI (1) SI0831097T1 (pt)
SV (1) SV1997000079A (pt)
TR (1) TR199900639T2 (pt)
TW (1) TW518335B (pt)
UA (1) UA56184C2 (pt)
WO (1) WO1998011893A1 (pt)
ZA (1) ZA978512B (pt)

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* Cited by examiner, † Cited by third party
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ZA978515B (en) * 1996-09-23 1999-03-23 Lilly Co Eli Intermediates and process for preparing olanzapine
US6617321B2 (en) 1997-09-30 2003-09-09 Eli Lilly And Company 2-methyl-thieno-benzodiazepine formulation
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US7022698B2 (en) 1999-12-28 2006-04-04 U & I Pharmaceuticals, Ltd. Pharmaceutical compositions containing new polymorphic forms of olanzapine and uses thereof
EP1246827B1 (en) * 1999-12-28 2005-04-13 Cipla Limited New polymorphic forms of olanzapine
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US6740753B2 (en) 2001-01-04 2004-05-25 Geneva Pharmaceuticals, Inc. Olanzapine crystal modification
EP1440074A1 (en) * 2001-10-29 2004-07-28 Dr. Reddy's Laboratories Ltd. Olanzapine dihydrate-ii a process for its preparation and use thereof
US7297789B2 (en) 2002-05-31 2007-11-20 Sandoz, Inc. Process of preparation of olanzapine form I
SI21270A (sl) 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
US7323459B2 (en) * 2002-12-24 2008-01-29 Teva Pharmaceutical Industries Ltd. Crystal forms, methods for their preparation and method for preparation of olanzapine
US6861422B2 (en) 2003-02-26 2005-03-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
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ATE504588T1 (de) 2004-01-27 2011-04-15 Synthon Bv Stabile salze von olanzapin
DE102004029784A1 (de) 2004-06-21 2006-01-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue 2-Benzylaminodihydropteridinone, Verfahren zur deren Herstellung und deren Verwendung als Arzneimittel
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DE102004033670A1 (de) 2004-07-09 2006-02-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Pyridodihydropyrazinone, Verfahren zu Ihrer Herstellung und Ihre Verwendung als Arzneimittel
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US20060058311A1 (en) 2004-08-14 2006-03-16 Boehringer Ingelheim International Gmbh Combinations for the treatment of diseases involving cell proliferation
US7759485B2 (en) 2004-08-14 2010-07-20 Boehringer Ingelheim International Gmbh Process for the manufacture of dihydropteridinones
US20060074088A1 (en) 2004-08-14 2006-04-06 Boehringer Ingelheim International Gmbh Dihydropteridinones for the treatment of cancer diseases
US20060035903A1 (en) 2004-08-14 2006-02-16 Boehringer Ingelheim International Gmbh Storage stable perfusion solution for dihydropteridinones
US7728134B2 (en) 2004-08-14 2010-06-01 Boehringer Ingelheim International Gmbh Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament
EP1630163A1 (de) 2004-08-25 2006-03-01 Boehringer Ingelheim Pharma GmbH & Co.KG Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
US7829700B2 (en) 2004-09-06 2010-11-09 Shasun Chemicals And Drugs Limited Process for preparation of a pharmaceutically pure polymorphic form I of Olanzapine
EP1797038B1 (en) 2004-09-29 2012-06-13 Bayer Pharma Aktiengesellschaft Thermodynamically stable form of bay 43-9006 tosylate
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
ES2526092T3 (es) * 2004-11-16 2015-01-05 Alkermes Pharma Ireland Limited Formulaciones de olanzapina en nanopartículas inyectables
DE102004058337A1 (de) 2004-12-02 2006-06-14 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten
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DE102005035891A1 (de) 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
WO2007067714A2 (en) * 2005-12-08 2007-06-14 The Mclean Hospital Corporation Treatment of sequelae of psychiatric disorders
US7834176B2 (en) * 2006-01-26 2010-11-16 Sandoz Ag Polymorph E of Olanzapine and preparation of anhydrous non-solvated crystalline polymorphic Form I of 2-methyl-4(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine (Olanzapine Form I) from the polymorphic Olanzapine Form E
US7439358B2 (en) 2006-02-08 2008-10-21 Boehringer Ingelheim International Gmbh Specific salt, anhydrous and crystalline form of a dihydropteridione derivative
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EP1852108A1 (en) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG DPP IV inhibitor formulations
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EP4151218A1 (en) 2012-05-14 2023-03-22 Boehringer Ingelheim International GmbH Linagliptin, a xanthine derivative as dpp-4 inhibitor, for use in the treatment of sirs and/or sepsis
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US5302716A (en) * 1986-01-16 1994-04-12 Schering Corporation Fused benzazepines
GB9009229D0 (en) * 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
US5229382A (en) * 1990-04-25 1993-07-20 Lilly Industries Limited 2-methyl-thieno-benzodiazepine
CA2097016A1 (en) * 1992-05-29 1993-11-30 John Fairhurst Pharmaceutical compounds
NZ289619A (en) 1994-06-28 1998-12-23 Grace W R & Co Bag with patches, the patches having overhang regions which are adhered together
IL117612A0 (en) * 1995-03-24 1996-07-23 Lilly Co Eli Granule formulation for olanzapine
US5631250A (en) * 1995-03-24 1997-05-20 Eli Lilly And Company Process and solvate of 2-methyl-thieno-benzodiazepine
EG23659A (en) * 1995-03-24 2007-03-26 Lilly Co Eli Process and crystal forms of methyl-thieno-benzodiazepine
EG24221A (en) * 1995-03-24 2008-11-10 Lilly Co Eli Process for preparing olanzapine

Also Published As

Publication number Publication date
EA199900325A1 (ru) 1999-08-26
CZ98999A3 (cs) 1999-08-11
UA56184C2 (uk) 2003-05-15
CN1146567C (zh) 2004-04-21
IL128956A0 (en) 2000-02-17
AU720366B2 (en) 2000-06-01
PL194074B1 (pl) 2007-04-30
TW518335B (en) 2003-01-21
YU15499A (sh) 2000-03-21
US6251895B1 (en) 2001-06-26
NO991339L (no) 1999-03-19
EP0831097A2 (en) 1998-03-25
AR009801A1 (es) 2000-05-03
KR20000048519A (ko) 2000-07-25
EA001881B1 (ru) 2001-10-22
DE69714165D1 (de) 2002-08-29
ES2180899T3 (es) 2003-02-16
RS49597B (sr) 2007-06-04
PE110298A1 (es) 1999-01-18
CN1234738A (zh) 1999-11-10
EG23815A (en) 2007-08-19
TR199900639T2 (xx) 1999-06-21
MY125467A (en) 2006-08-30
HU226167B1 (hu) 2008-05-28
CA2266444C (en) 2007-01-09
ATE221074T1 (de) 2002-08-15
JP2001500878A (ja) 2001-01-23
EP0831097B1 (en) 2002-07-24
EP0831097A3 (en) 1998-04-29
CZ299247B6 (cs) 2008-05-28
ID21924A (id) 1999-08-12
SI0831097T1 (en) 2003-02-28
HUP0000065A2 (hu) 2000-06-28
ZA978512B (en) 1999-03-23
WO1998011893A1 (en) 1998-03-26
DK0831097T3 (da) 2002-09-02
AU4424197A (en) 1998-04-14
PT831097E (pt) 2002-10-31
DE69714165T2 (de) 2003-01-23
CO4900057A1 (es) 2000-03-27
HK1009809A1 (en) 1999-06-11
SV1997000079A (es) 1999-01-13
KR100516088B1 (ko) 2005-09-22
NO323979B1 (no) 2007-07-30
NO991339D0 (no) 1999-03-19
PL332541A1 (en) 1999-09-13
HUP0000065A3 (en) 2000-11-28
NZ334346A (en) 2000-05-26
CA2266444A1 (en) 1998-03-26

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B12F Other appeals [chapter 12.6 patent gazette]
B07B Technical examination (opinion): publication cancelled [chapter 7.2 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 16A ANUIDADE

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2225 DE 27/08/2013.