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BR9708677A - Piperidinas e pirrolidinas - Google Patents

Piperidinas e pirrolidinas

Info

Publication number
BR9708677A
BR9708677A BR9708677A BR9708677A BR9708677A BR 9708677 A BR9708677 A BR 9708677A BR 9708677 A BR9708677 A BR 9708677A BR 9708677 A BR9708677 A BR 9708677A BR 9708677 A BR9708677 A BR 9708677A
Authority
BR
Brazil
Prior art keywords
pyrrolidines
piperidines
Prior art date
Application number
BR9708677A
Other languages
English (en)
Inventor
Joachim Maerz
Henning Boettcher
Ralf Devant
Hartmut Greiner
Gerd Batoszyk
Juergen Harting
Christoph Seyfried
Ronny Anderson Bengt
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of BR9708677A publication Critical patent/BR9708677A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
BR9708677A 1996-04-18 1997-04-14 Piperidinas e pirrolidinas BR9708677A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19615232A DE19615232A1 (de) 1996-04-18 1996-04-18 Neue Carbamoylderivate und deren Verwendung als 5-HT ¶1¶¶A¶-Antagonisten
PCT/EP1997/001853 WO1997040038A1 (en) 1996-04-18 1997-04-14 Piperidines and pyrrolidines

Publications (1)

Publication Number Publication Date
BR9708677A true BR9708677A (pt) 1999-08-03

Family

ID=7791576

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9708677A BR9708677A (pt) 1996-04-18 1997-04-14 Piperidinas e pirrolidinas

Country Status (15)

Country Link
EP (1) EP0898569A1 (pt)
JP (1) JP2000508670A (pt)
KR (1) KR20000005505A (pt)
AR (1) AR006690A1 (pt)
AU (1) AU2696797A (pt)
BR (1) BR9708677A (pt)
CA (1) CA2252385A1 (pt)
CZ (1) CZ330598A3 (pt)
DE (1) DE19615232A1 (pt)
HU (1) HUP9901389A3 (pt)
NO (1) NO984861D0 (pt)
PL (1) PL329351A1 (pt)
SK (1) SK141998A3 (pt)
WO (1) WO1997040038A1 (pt)
ZA (1) ZA973301B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19756036A1 (de) * 1997-12-17 1999-06-24 Merck Patent Gmbh Amid- und Harnstoffderivate
PT1068199E (pt) * 1998-04-08 2003-02-28 Wyeth Corp N-ariloxietil-indoli-alquilaminas para o tratamento da depressao
US6150533A (en) * 1998-04-08 2000-11-21 American Home Products Corp. N-aryloxyethyl-indoly-alkylamines for the treatment of depression
AR015035A1 (es) * 1998-04-29 2001-04-11 American Home Prod Agentes serotonergicos, composicion farmaceutica que los contiene y su uso para la manufactura de un medicamento
CA2334254A1 (en) * 1998-06-15 1999-12-23 American Home Products Corporation Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonergic agents
US6376494B1 (en) 1998-06-15 2002-04-23 American Home Products Corporation Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonergic agents
US6326381B1 (en) 1998-12-17 2001-12-04 American Home Products Corporation Arylpiperidine and aryl-1,2,5,6-tetrahydropyidine amide derivates
WO2000035874A1 (en) * 1998-12-17 2000-06-22 American Home Products Corporation Arylpiperidine and aryl-1,2,5,6-tetrahydropyridine amide derivatives having 5ht1a receptor activity
US6239126B1 (en) 1998-12-17 2001-05-29 American Home Products Corporation Arylpiperidine and aryl-1,2,5,6-tetra-hydropyridine urea derivatives
WO2000035875A1 (en) * 1998-12-17 2000-06-22 American Home Products Corporation Arylpiperidine and aryl-1,2,5,6-tetrahydropyridine urea derivatives having 5ht1a receptor activity
JP2002535365A (ja) * 1999-01-28 2002-10-22 ブリストル−マイヤーズ スクイブ カンパニー 抗うつ性複素環化合物
JP4159358B2 (ja) * 2000-12-27 2008-10-01 アクシオジェネシス アーゲー 分化中の胚幹細胞、成体幹細胞および胚生殖系細胞を細胞特異的および成長特異的に選択するためのシステム
KR100459917B1 (ko) * 2001-12-14 2004-12-03 (주)바이오뉴트리젠 페놀릭산 유도체 및 이를 포함하는 혈중 지질 농도 관련질환의 예방 및 치료용 조성물
DE10337184A1 (de) * 2003-08-13 2005-03-10 Gruenenthal Gmbh Substituierte 3-Pyrrolidin-Indol-Derivate
UY36390A (es) 2014-11-05 2016-06-01 Flexus Biosciences Inc Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen
US11242319B2 (en) 2014-11-05 2022-02-08 Flexus Biosciences, Inc. Immunoregulatory agents
BR112023025340A2 (pt) * 2021-06-02 2024-02-20 Compass Pathfinder Ltd Compostos de triptamina fluorada, análogos dos mesmos e métodos usando os mesmos
KR20240144259A (ko) 2022-01-29 2024-10-02 수벤 라이프 사이언시스 리미티드 정신 장애 치료를 위한 벤조이소티아졸 및 벤조이속사졸 화합물

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3226392A (en) * 1960-03-07 1965-12-28 Sterling Drug Inc 1-[n-aryl-n-acylaminoalkyl]-4-aryl-1,2,3,6-tetrahydropyridines, the corresponding piperidines and their salts
US3647790A (en) * 1969-04-08 1972-03-07 American Home Prod Ouinoxalinyl-oxazolidines and -oxazines
US4782071A (en) * 1986-11-03 1988-11-01 Warner-Lambert Company Tetrasubstituted urea cholinergic agents
MX9201991A (es) * 1991-05-02 1992-11-01 Jonh Wyeth & Brother Limited Derivados de piperazina y procedimiento para su preparacion.
FR2706894A1 (en) * 1993-06-22 1994-12-30 Synthelabo N-Phenyl-N-(piperidinoalkyl)arylamide derivatives, their preparation and their application in therapeutics
GB9314758D0 (en) * 1993-07-16 1993-08-25 Wyeth John & Brother Ltd Heterocyclic derivatives
EP0661266A1 (en) * 1993-12-27 1995-07-05 Toa Eiyo Ltd. Substituted cyclic amine compounds as 5HT2 antagonists
GB9411099D0 (en) * 1994-06-03 1994-07-27 Wyeth John & Brother Ltd Piperazine derivatives

Also Published As

Publication number Publication date
WO1997040038A1 (en) 1997-10-30
HUP9901389A2 (hu) 1999-08-30
PL329351A1 (en) 1999-03-29
CZ330598A3 (cs) 1999-01-13
AR006690A1 (es) 1999-09-08
KR20000005505A (ko) 2000-01-25
ZA973301B (en) 1997-10-24
SK141998A3 (en) 1999-03-12
NO984861L (no) 1998-10-16
NO984861D0 (no) 1998-10-16
EP0898569A1 (en) 1999-03-03
AU2696797A (en) 1997-11-12
HUP9901389A3 (en) 2000-09-28
JP2000508670A (ja) 2000-07-11
CA2252385A1 (en) 1997-10-30
DE19615232A1 (de) 1997-10-23

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]