BR9708530A - Inibidores cíclicos de adesão - Google Patents

Inibidores cíclicos de adesão

Info

Publication number: BR9708530A
Authority: BR; Brazil
Prior art keywords: adhesion inhibitors; cyclic adhesion; cyclic; inhibitors; adhesion
Prior art date: 1996-04-06

Application number

BR9708530A

Other languages

English (en)

Inventor

Alfred Jonczyk

Simon Goodman

Beate Diefenbach

Horst Kessler

Marcus Koppitz

Original Assignee

Merck Patent Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-06

Filing date

1997-04-02

Publication date

1999-08-03

1997-04-02 Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh

1999-08-03 Publication of BR9708530A publication Critical patent/BR9708530A/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Hematology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Zoology (AREA)
Orthopedic Medicine & Surgery (AREA)
Toxicology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Diabetes (AREA)
Dermatology (AREA)
Pain & Pain Management (AREA)
Urology & Nephrology (AREA)
Immunology (AREA)
Epidemiology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

BR9708530A 1996-04-06 1997-04-02 Inibidores cíclicos de adesão BR9708530A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19613933A DE19613933A1 (de)	1996-04-06	1996-04-06	Cyclische Adhäsionsinhibitoren
PCT/EP1997/001657 WO1997038009A1 (de)	1996-04-06	1997-04-02	Cyclische adhäsionsinhibitoren

Publications (1)

Publication Number	Publication Date
BR9708530A true BR9708530A (pt)	1999-08-03

Family

ID=7790744

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9708530A BR9708530A (pt)	1996-04-06	1997-04-02	Inibidores cíclicos de adesão

Country Status (24)

Country	Link
US (1)	US6127335A (pt)
EP (1)	EP0904285B1 (pt)
JP (1)	JP4115530B2 (pt)
KR (1)	KR100438378B1 (pt)
CN (1)	CN1119351C (pt)
AR (1)	AR006523A1 (pt)
AT (1)	ATE224402T1 (pt)
AU (1)	AU717496B2 (pt)
BR (1)	BR9708530A (pt)
CA (1)	CA2250861C (pt)
CZ (1)	CZ291510B6 (pt)
DE (2)	DE19613933A1 (pt)
DK (1)	DK0904285T3 (pt)
ES (1)	ES2183159T3 (pt)
HU (1)	HUP9903631A3 (pt)
NO (1)	NO984667L (pt)
PL (1)	PL187924B1 (pt)
PT (1)	PT904285E (pt)
RU (1)	RU2184121C2 (pt)
SK (1)	SK283718B6 (pt)
TW (1)	TW570929B (pt)
UA (1)	UA61071C2 (pt)
WO (1)	WO1997038009A1 (pt)
ZA (1)	ZA972843B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6833373B1 (en)	1998-12-23	2004-12-21	G.D. Searle & Co.	Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
IL143901A0 (en)	1998-12-23	2002-04-21	Searle & Co	Use of cyclooxygenase-2- inhibitor, a matrix metallaproteinase inhibitor, an antineoplastic agent and optionally radiation as a combination treatment of neoplasia
US6858598B1 (en)	1998-12-23	2005-02-22	G. D. Searle & Co.	Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6521593B1 (en) *	1999-02-01	2003-02-18	Childrens Hospital Los Angeles	Methods for inhibiting brain tumor growth
UA71608C2 (en)	1999-03-11	2004-12-15	Merck Patent Gmbh	A method for producing the cyclic pentapeptide
SK5902003A3 (en)	2000-11-01	2003-08-05	Merck Patent Gmbh	Methods and compositions for the treatment of diseases of the eye
UA75898C2 (en) *	2000-11-14	2006-06-15	Merck Patent Gmbh	Method for prophylaxis and treatment of eye diseases using antagonist of integrin receptors
JP4499327B2 (ja) *	2001-12-06	2010-07-07	松崎浩巳	拡径器具および手術器具セット
JP2005533001A (ja) *	2002-03-04	2005-11-04	メディミューン，インコーポレーテッド	インテグリンαｖβ３アンタゴニストを他の物質と併用投与する癌の予防または治療方法
JP2005525368A (ja) *	2002-03-04	2005-08-25	メディミューン，インコーポレーテッド	インテグリンαｖβ３アンタゴニストをＨＭＧ−ＣｏＡ還元酵素阻害剤またはビスフォスフォネートと併用投与する障害の予防または治療方法
AU2003218110A1 (en)	2002-03-12	2003-09-29	Bristol-Myers Squibb Company	C3-cyano epothilone derivatives
ITRM20020402A1 (it) *	2002-07-29	2004-01-29	Sigma Tau Ind Farmaceuti	Derivati fluoro-alchil-ciclopeptidi ad attivita' anti-integrine.
US20040224986A1 (en)	2002-08-16	2004-11-11	Bart De Corte	Piperidinyl targeting compounds that selectively bind integrins
US20040077684A1 (en) *	2002-08-16	2004-04-22	Bart De Corte	Piperidinyl compounds that selectively bind integrins
RU2234331C1 (ru) *	2002-12-30	2004-08-20	Смирнов Алексей Владимирович	Лекарственное средство
WO2004066956A2 (en) *	2003-01-30	2004-08-12	Medimmune, Inc.	Uses of integrin alphavbeta3 antagonists
CN101990425B (zh) *	2008-04-08	2016-01-20	默克专利股份有限公司	包含环肽的组合物和使用方法
US10745444B2 (en) *	2017-04-17	2020-08-18	National Tsing Hua University	Cyclopeptide, pharmaceutical or cosmetic composition comprising the same and method for preparing the same
EP3392262B1 (en) *	2017-04-17	2021-08-18	National Tsing Hua University	Cyclopeptide, pharmaceutical or cosmetic composition comprising the same and method for preparing the same
US10494403B2 (en)	2018-03-06	2019-12-03	Ciphore Biomed Technology Limited Company	Cyclopeptide, pharmaceutical or cosmetic composition comprising the same and method for preparing the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT89279B (pt) *	1987-12-21	1993-08-31	Sandoz Sa	Processo para a preparacao de uma nova forma cristalina de ciclosporinas e de composicoes farmaceuticas que as contem
CN1077279A (zh) *	1992-04-09	1993-10-13	北京矿冶研究总院	雷管桥丝发火电阻安全检测仪
UA43823C2 (uk) *	1992-07-06	2002-01-15	Мерк Патент Геселлшафт Міт Бесшренктер Хафтунг	ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ДЛЯ ІНГІБУВАННЯ ІНТЕГРИН <font face="Symbol">a</font><sub>V</sub><font face="Symbol">b</font><sub>3</sub>-ОПОСЕРЕДКОВАНОЇ КЛІТИННОЇ АДГЕЗІЇ КЛІТИН ССАВЦІВ, СПОСІБ ЛІКУВАННЯ ТА ПРОФІЛАКТИКИ ЗАХВОРЮВАННЯ, АСОЦІЙОВАНОГО З ПОРУШЕННЯМ АДГЕЗІЇ КЛІТИН, СПОСІБ БЛОКУВАННЯ ЗВ'ЯЗУВАННЯ ФІБРИНОГЕНОМ ІНТЕГРИНУ, КОМПОЗИЦІЯ ДЛЯ ЗАГОЄННЯ РАН
AU5978594A (en) *	1993-02-04	1994-08-29	Banyu Pharmaceutical Co., Ltd.	Novel cyclic pentapeptide
DE4310643A1 (de) *	1993-04-01	1994-10-06	Merck Patent Gmbh	Cyclische Adhäsionsinhibitoren
DE19534177A1 (de) *	1995-09-15	1997-03-20	Merck Patent Gmbh	Cyclische Adhäsionsinhibitoren

1996
- 1996-04-06 DE DE19613933A patent/DE19613933A1/de not_active Withdrawn
1997
- 1997-02-04 UA UA98105792A patent/UA61071C2/uk unknown
- 1997-04-02 RU RU98120600/04A patent/RU2184121C2/ru active
- 1997-04-02 JP JP53581497A patent/JP4115530B2/ja not_active Expired - Lifetime
- 1997-04-02 CA CA002250861A patent/CA2250861C/en not_active Expired - Fee Related
- 1997-04-02 AT AT97917291T patent/ATE224402T1/de active
- 1997-04-02 DE DE59708269T patent/DE59708269D1/de not_active Expired - Lifetime
- 1997-04-02 CZ CZ19983203A patent/CZ291510B6/cs not_active IP Right Cessation
- 1997-04-02 BR BR9708530A patent/BR9708530A/pt not_active Application Discontinuation
- 1997-04-02 ES ES97917291T patent/ES2183159T3/es not_active Expired - Lifetime
- 1997-04-02 CN CN97194526A patent/CN1119351C/zh not_active Expired - Lifetime
- 1997-04-02 DK DK97917291T patent/DK0904285T3/da active
- 1997-04-02 PT PT97917291T patent/PT904285E/pt unknown
- 1997-04-02 HU HU9903631A patent/HUP9903631A3/hu unknown
- 1997-04-02 KR KR10-1998-0707888A patent/KR100438378B1/ko not_active Expired - Fee Related
- 1997-04-02 PL PL32915497A patent/PL187924B1/pl not_active IP Right Cessation
- 1997-04-02 WO PCT/EP1997/001657 patent/WO1997038009A1/de not_active Ceased
- 1997-04-02 EP EP97917291A patent/EP0904285B1/de not_active Expired - Lifetime
- 1997-04-02 SK SK1364-98A patent/SK283718B6/sk unknown
- 1997-04-02 AU AU25688/97A patent/AU717496B2/en not_active Ceased
- 1997-04-02 US US09/155,721 patent/US6127335A/en not_active Expired - Lifetime
- 1997-04-03 ZA ZA9702843A patent/ZA972843B/xx unknown
- 1997-04-04 AR ARP970101342A patent/AR006523A1/es not_active Application Discontinuation
- 1997-07-08 TW TW086104359A patent/TW570929B/zh active
1998
- 1998-10-06 NO NO984667A patent/NO984667L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
DK0904285T3 (da)	2003-01-27
PL187924B1 (pl)	2004-11-30
JP4115530B2 (ja)	2008-07-09
KR20000005210A (ko)	2000-01-25
US6127335A (en)	2000-10-03
ATE224402T1 (de)	2002-10-15
CN1218478A (zh)	1999-06-02
PT904285E (pt)	2003-02-28
HUP9903631A3 (en)	2000-04-28
CZ291510B6 (cs)	2003-03-12
CN1119351C (zh)	2003-08-27
AU717496B2 (en)	2000-03-30
ZA972843B (en)	1998-02-19
CZ320398A3 (cs)	1999-01-13
NO984667D0 (no)	1998-10-06
TW570929B (en)	2004-01-11
SK136498A3 (en)	1999-05-07
HUP9903631A2 (hu)	2000-03-28
AR006523A1 (es)	1999-09-08
EP0904285A1 (de)	1999-03-31
ES2183159T3 (es)	2003-03-16
DE59708269D1 (de)	2002-10-24
EP0904285B1 (de)	2002-09-18
JP2000510102A (ja)	2000-08-08
KR100438378B1 (ko)	2004-08-25
PL329154A1 (en)	1999-03-15
CA2250861A1 (en)	1997-10-16
SK283718B6 (sk)	2003-12-02
DE19613933A1 (de)	1997-10-09
NO984667L (no)	1998-10-06
WO1997038009A1 (de)	1997-10-16
AU2568897A (en)	1997-10-29
UA61071C2 (en)	2003-11-17
CA2250861C (en)	2008-07-15
RU2184121C2 (ru)	2002-06-27

Publication	Publication Date	Title
BR9603751A (pt)	1998-06-02	Inibidores de adesão cíclica
DE69621026D1 (de)	2002-06-06	Zyklische gmp-spezifische phosphodiesteraseinhibitoren
BR9609782A (pt)	1999-03-09	Inibidores de adesão culular
FI973087L (fi)	1997-09-22	Soluadheesion inhibiittoreita
PT958287E (pt)	2002-12-31	Inibidores de sulfamida-metaloprotease
NO971727D0 (no)	1997-04-15	Belegningsblanding
DE69702291D1 (de)	2000-07-20	Beschichtungsvorrichtung
PT858464E (pt)	2003-08-29	Inibidores de trombina
BR9708530A (pt)	1999-08-03	Inibidores cíclicos de adesão
NO964600D0 (no)	1996-10-30	Slagverktöy
DE59707990D1 (de)	2002-09-26	Adhäsive
ID26488A (id)	2001-01-11	Pelapis elastis
PT956294E (pt)	2004-10-29	Inibidores da trombina
PT927183E (pt)	2004-12-31	Inibidores espirociclicos de metaloproteases
DE69709833D1 (de)	2002-02-28	Wellenformentzerrer
PT948483E (pt)	2002-08-30	Inibidores da farnesil-transferase
PT863916E (pt)	2002-07-31	Tripeptidos de polifluoroalquil triptofano inibidores de trombina
DE59701322D1 (de)	2000-04-27	Flüssigkeitsdurchlässiger belag
DE69720957T2 (de)	2004-01-29	Ace-hemmer
BR9610514A (pt)	1999-03-30	Inibidores cicloantihelmínticos
SI0904285T1 (en)	2003-04-30	Cyclic adhesion inhibitors
DK0942053T3 (da)	2002-11-25	Coatingmateriale
KR970049480U (ko)	1997-08-12	접착테이프용 첩부기
NO962710D0 (no)	1996-06-26	Söylekonstruksjon

Legal Events

Date	Code	Title	Description
2004-12-07	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2005-04-26	B09B	Patent application refused [chapter 9.2 patent gazette]