BR9708518A - Moduladores de fator associado a receptor tnf (traf) sua preparação e uso - Google Patents

Moduladores de fator associado a receptor tnf (traf) sua preparação e uso

Info

Publication number: BR9708518A
Authority: BR; Brazil
Prior art keywords: traf; modulators; preparation; tnf receptor; factor associated
Prior art date: 1996-04-02

Application number

BR9708518A

Other languages

English (en)

Inventor

David Wallach

Nikolai Malinin

Mark Boldin

Andrei Kovalenko

Igor Mett

Original Assignee

Yeda Res & Dev

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-02

Filing date

1997-04-01

Publication date

1999-08-03

1996-04-02 Priority claimed from IL11780096A external-priority patent/IL117800A0/xx

1996-08-26 Priority claimed from IL11913396A external-priority patent/IL119133A0/xx

1997-04-01 Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev

1999-08-03 Publication of BR9708518A publication Critical patent/BR9708518A/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Biochemistry (AREA)
Immunology (AREA)
Wood Science & Technology (AREA)
Gastroenterology & Hepatology (AREA)
General Engineering & Computer Science (AREA)
Toxicology (AREA)
Microbiology (AREA)
Biomedical Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biotechnology (AREA)
Biophysics (AREA)
Pain & Pain Management (AREA)
Transplantation (AREA)
Rheumatology (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

BR9708518A 1996-04-02 1997-04-01 Moduladores de fator associado a receptor tnf (traf) sua preparação e uso BR9708518A (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
IL11780096A IL117800A0 (en)	1996-04-02	1996-04-02	Modulators of TNF receptor associated factor (TRAF) their preparation and use
IL11913396A IL119133A0 (en)	1996-08-26	1996-08-26	Modulators of TNF receptor associated factor (TRAF) their preparation and use
PCT/IL1997/000117 WO1997037016A1 (en)	1996-04-02	1997-04-01	Modulators of tnf receptor associated factor (traf), their preparation and use

Publications (1)

Publication Number	Publication Date
BR9708518A true BR9708518A (pt)	1999-08-03

Family

ID=26323248

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9708518A BR9708518A (pt)	1996-04-02	1997-04-01	Moduladores de fator associado a receptor tnf (traf) sua preparação e uso

Country Status (22)

Country	Link
US (2)	US7485456B1 (pt)
EP (1)	EP0894130B1 (pt)
JP (1)	JP4180114B2 (pt)
CN (1)	CN1197966C (pt)
AT (1)	ATE380866T1 (pt)
AU (1)	AU732793B2 (pt)
BG (1)	BG64755B1 (pt)
BR (1)	BR9708518A (pt)
CA (1)	CA2250085C (pt)
CZ (3)	CZ299682B6 (pt)
DE (1)	DE69738370T2 (pt)
DK (1)	DK0894130T3 (pt)
EA (1)	EA004309B1 (pt)
EE (1)	EE04783B1 (pt)
ES (1)	ES2294796T3 (pt)
HU (1)	HU226328B1 (pt)
NO (1)	NO327054B1 (pt)
NZ (1)	NZ331902A (pt)
PT (1)	PT894130E (pt)
SK (3)	SK287085B6 (pt)
UA (1)	UA71889C2 (pt)
WO (1)	WO1997037016A1 (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA71889C2 (uk) *	1996-04-02	2005-01-17	Йєда Рісерч Енд Дівелопмент Ко. Лтд.	Модулятори зв'язаного з рецептором tnf фактора (traf), їх одержання та застосування
US5843721A (en) *	1997-07-03	1998-12-01	Tularik Inc.	Nucleic acids encoding human NIK protein
JP2003525567A (ja) *	1997-11-07	2003-09-02	ジェネティックス・インスチチュート・リミテッド・ライアビリティ・カンパニー	分泌蛋白およびそれらをコードするポリヌクレオチド
US6265538B1 (en) *	1998-02-27	2001-07-24	The Regents Of The University Of California	Inhibitor of the inflammatory response induced by the TNFA and IL-1
DE69928244T2 (de) *	1998-05-06	2006-08-10	Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw.	Inhibitoren der nf-kb aktivierung
TR200100624T2 (tr) *	1998-08-18	2001-08-21	Aktiengesellschaft Basf	TPL-2/Cot kinaz ve kullanım yöntemleri.
IL131719A0 (en) *	1999-09-02	2001-03-19	Yeda Res & Dev	Iren protein its preparation and use
GB9930616D0 (en) *	1999-12-24	2000-02-16	Mathilda & Terence Kennedy Ins	Activation and inhibition of the immune system
US20040109854A1 (en) *	2001-02-21	2004-06-10	Zang-Hee Lee	Novel traf6 inhibiting protein
AU2002350412B2 (en)	2001-06-22	2006-06-15	Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw	Abin-mediated hepatitis protection
EP1499729B9 (en) *	2002-04-18	2012-03-14	Yeda Research And Development Co., Ltd.	Derivatives of the nf-kappab inducing enzyme, their preparation and use
IL158287A0 (en) *	2003-10-07	2004-05-12	Yeda Res & Dev	Antibodies to nik, their preparation and use
WO2005033145A1 (en) *	2003-10-07	2005-04-14	Yeda Research And Development Co. Ltd.	Antibodies to nik, their preparation and use
CA2547459C (en) *	2003-11-30	2013-10-08	Yeda Research And Development Co. Ltd	Modulators of nik-siva complex formation for treating immune disorders
IL173104A0 (en) *	2006-01-12	2006-06-11	Yeda Res & Dev	Siva and ubiquintination
ES2752025T3 (es)	2008-07-25	2020-04-02	Wagner Richard W	Métodos de cribado de proteínas
GB201012420D0 (en)	2010-07-23	2010-09-08	Univ Erasmus Medical Ct	Foetal heamoglobin inhibitor
CA2808539C (en)	2010-08-25	2021-05-25	Atyr Pharma, Inc.	Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of tyrosyl-trna synthetases
CN105177032B (zh) *	2010-09-01	2019-05-10	山东新时代药业有限公司	新型人肿瘤坏死因子受体-Fc融合基因及其产物蛋白
WO2012123522A1 (en)	2011-03-16	2012-09-20	F. Hoffmann-La Roche Ag	6,5-heterocyclic propargylic alcohol compounds and uses therefor
ES2810424T3 (es)	2011-06-30	2021-03-08	Genzyme Corp	Inhibidores de la activación de células T
EP2734232B1 (en)	2011-07-19	2017-11-01	Philogen S.p.A.	Sequential anti-ctla4 and targeted il-2 therapy
UY34317A (es)	2011-09-12	2013-02-28	Genzyme Corp	Anticuerpo antireceptor de célula T (alfa)/ß
CA2974651A1 (en)	2014-01-24	2015-07-30	Children's Hospital Of Eastern Ontario Research Institute Inc.	Smc combination therapy for the treatment of cancer
CN105986001B (zh) *	2015-02-12	2019-12-03	上海交通大学	一种基于膜结合蛋白和荧光互补的高通量猎物拮抗剂筛选方法
EP3313887A2 (en)	2015-06-26	2018-05-02	MAB Discovery GmbH	Monoclonal anti-il-1racp antibodies
WO2020206063A1 (en)	2019-04-03	2020-10-08	Genzyme Corporation	Anti-alpha beta tcr binding polypeptides with reduced fragmentation
TW202428613A (zh)	2022-09-21	2024-07-16	法商賽諾菲生物技術公司	人源化抗il-1r3抗體及使用方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5641876A (en) *	1990-01-05	1997-06-24	Cornell Research Foundation, Inc.	Rice actin gene and promoter
EP0841934A1 (en) *	1995-08-02	1998-05-20	Teresa J. Ingram	Composition for administration to patients with chronic fatigue syndrome and acquired immune deficiency syndrome
AU6692996A (en) *	1995-08-08	1997-03-05	Tularik Inc.	Inhibitors of apoptosis
US5804412A (en) *	1996-04-01	1998-09-08	The Regents Of The University Of California	Nucleic acids encoding sorting nexins and methods of using same
UA71889C2 (uk) *	1996-04-02	2005-01-17	Йєда Рісерч Енд Дівелопмент Ко. Лтд.	Модулятори зв'язаного з рецептором tnf фактора (traf), їх одержання та застосування
EP0904346A4 (en)	1996-05-08	2000-11-29	Henkel Corp	ALKYL POLYGLYCOSIDE ETHER CARBOXYLATES
US5843721A (en) *	1997-07-03	1998-12-01	Tularik Inc.	Nucleic acids encoding human NIK protein

1997
- 1997-01-04 UA UA98105743A patent/UA71889C2/uk unknown
- 1997-04-01 AU AU21755/97A patent/AU732793B2/en not_active Expired
- 1997-04-01 SK SK1361-98A patent/SK287085B6/sk not_active IP Right Cessation
- 1997-04-01 US US09/155,676 patent/US7485456B1/en not_active Expired - Fee Related
- 1997-04-01 WO PCT/IL1997/000117 patent/WO1997037016A1/en not_active Ceased
- 1997-04-01 PT PT97914534T patent/PT894130E/pt unknown
- 1997-04-01 CZ CZ0318398A patent/CZ299682B6/cs not_active IP Right Cessation
- 1997-04-01 DK DK97914534T patent/DK0894130T3/da active
- 1997-04-01 HU HU9902429A patent/HU226328B1/hu unknown
- 1997-04-01 SK SK50017-2007A patent/SK287890B6/sk not_active IP Right Cessation
- 1997-04-01 JP JP53509997A patent/JP4180114B2/ja not_active Expired - Lifetime
- 1997-04-01 EE EE9800322A patent/EE04783B1/xx unknown
- 1997-04-01 EA EA199800885A patent/EA004309B1/ru not_active IP Right Cessation
- 1997-04-01 SK SK50016-2007A patent/SK287889B6/sk not_active IP Right Cessation
- 1997-04-01 CA CA002250085A patent/CA2250085C/en not_active Expired - Lifetime
- 1997-04-01 BR BR9708518A patent/BR9708518A/pt not_active Application Discontinuation
- 1997-04-01 AT AT97914534T patent/ATE380866T1/de active
- 1997-04-01 CZ CZ20060017A patent/CZ298866B6/cs not_active IP Right Cessation
- 1997-04-01 EP EP97914534A patent/EP0894130B1/en not_active Expired - Lifetime
- 1997-04-01 CZ CZ20060018A patent/CZ299094B6/cs not_active IP Right Cessation
- 1997-04-01 CN CNB971951934A patent/CN1197966C/zh not_active Expired - Lifetime
- 1997-04-01 ES ES97914534T patent/ES2294796T3/es not_active Expired - Lifetime
- 1997-04-01 DE DE69738370T patent/DE69738370T2/de not_active Expired - Lifetime
- 1997-04-01 NZ NZ331902A patent/NZ331902A/en not_active IP Right Cessation
1998
- 1998-09-29 NO NO19984551A patent/NO327054B1/no not_active IP Right Cessation
- 1998-10-07 BG BG102817A patent/BG64755B1/bg unknown
2009
- 2009-02-03 US US12/365,136 patent/US8236507B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JP4180114B2 (ja)	2008-11-12
BG102817A (en)	1999-05-31
UA71889C2 (uk)	2005-01-17
EE9800322A (et)	1999-04-15
CN1221449A (zh)	1999-06-30
EP0894130A1 (en)	1999-02-03
SK287890B6 (sk)	2012-03-02
CZ299682B6 (cs)	2008-10-15
DE69738370D1 (de)	2008-01-24
US20090291888A1 (en)	2009-11-26
EA004309B1 (ru)	2004-02-26
EP0894130B1 (en)	2007-12-12
NZ331902A (en)	2000-02-28
SK136198A3 (en)	1999-05-07
JP2000507826A (ja)	2000-06-27
WO1997037016A1 (en)	1997-10-09
SK287085B6 (sk)	2009-11-05
EE04783B1 (et)	2007-02-15
AU2175597A (en)	1997-10-22
SK287889B6 (sk)	2012-03-02
CN1197966C (zh)	2005-04-20
ES2294796T3 (es)	2008-04-01
CA2250085A1 (en)	1997-10-09
CA2250085C (en)	2009-10-20
HUP9902429A2 (hu)	1999-10-28
US7485456B1 (en)	2009-02-03
DK0894130T3 (da)	2008-01-07
CZ298866B6 (cs)	2008-02-27
CZ299094B6 (cs)	2008-04-23
NO984551D0 (no)	1998-09-29
NO984551L (no)	1998-11-24
US8236507B2 (en)	2012-08-07
ATE380866T1 (de)	2007-12-15
NO327054B1 (no)	2009-04-14
AU732793B2 (en)	2001-05-03
DE69738370T2 (de)	2008-12-04
HK1018910A1 (en)	2000-01-07
CZ318398A3 (cs)	1999-05-12
EA199800885A1 (ru)	1999-04-29
HU226328B1 (en)	2008-09-29
PT894130E (pt)	2008-01-14
BG64755B1 (bg)	2006-02-28
HUP9902429A3 (en)	2001-11-28

Publication	Publication Date	Title
BR9708518A (pt)	1999-08-03	Moduladores de fator associado a receptor tnf (traf) sua preparação e uso
DE69022559D1 (de)	1995-10-26	Expression des rekombinanten Tumor-Nekrosisfaktor-Bindungsproteins I (TBP-I).
DK1012274T4 (da)	2011-07-25	Dødsdomæneholdig receptor-4 (DR4: dødsreceptor 4), medlem af TNF-receptorsuperfamilien og som binder til TRAIL (Apo-2L)
CY1108175T1 (el)	2014-02-12	ΠΟΛΥΠΕΠΤΙΔΙΟ DcR3, ΟΜΟΛΟΓΟ TNFR
WO1998041629A3 (en)	1998-10-29	Death domain containing receptor 5
IL193886A0 (en)	2009-05-04	Antibodies that bind to ldcam sequences
WO1996034107A3 (en)	1997-04-24	Antiviral proteins, dna coding sequences therefor, and uses thereof
DE69834852D1 (de)	2006-07-20	NL3 TIE Rezeptortyrosinekinase Ligandhomologe
NO961115L (no)	1996-03-19	Humane metabotrope glutamatreseptorsubtyper (HMR4, HMR6, HMR7) og relaterte DNA forbindelser
PT93910A (pt)	1991-01-08	Prodesso para a preparacao de uma proteina heterologa mediante secrecao a partir de uma celula
NO960767D0 (no)	1996-02-26	Protocadherinproteiner og deres anvendelse
FI964509A7 (fi)	1997-01-08	TNF/NGF-superperhereseptoreiden muuntajia ja liukoisia, oligomeerisiä superperhereseptoreita
WO2002036769A3 (en)	2003-01-30	Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof
TW200716746A (en)	2007-05-01	Methods for identifying a compound modulating the binding between polypeptides
WO2000066156A8 (en)	2001-07-26	Death domain containing receptor 5
NZ315514A (en)	1998-12-23	Tumour necrosis factor associated factor (traf) inhibitors including traf polypeptide, murine nucleotide sequence and associated assays
FI863626A7 (fi)	1986-09-09	DNA-sekvenssejä, yhdistelmä-DNA -molekyylejä ja menetelmiä ihmisen lip okortiinin kaltaisia polypeptidejä.
WO2000024771A3 (en)	2000-11-09	Nucleic acids encoding osteoprotegerin-like proteins and methods of using same
EP0643728A4 (en)	1995-07-19	PROTEIN RELATED TO INTERCELLULAR ADHESION MOLECULES.
AU5166200A (en)	2000-12-18	Human tumor necrosis factor receptor tr10
ATE408687T1 (de)	2008-10-15	Semaphorin polypeptide
MX9605531A (es)	1998-02-28	Modulador de receptores de la superfamilia de factor de necrosis tumoral/factor de crecimiento de nervio y receptores oligomericos solubles de la superfamilia de factor de necrosis tumoral/factor de crecimiento necrotico.
AR008064A1 (es)	1999-12-09	Una proteina ligante del factor de necrosis tumoral truncada de bajo peso molecular (tnf bp), un polinucleotido codificante de dicha proteina, un vector, una celula hospedante, metodos para producir dicha proteina, una composicion farmaceutica, metodo para tratar una enfermedad mediada por tnf bp y usos de dicha proteina.

Legal Events

Date	Code	Title	Description
2007-02-06	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2007-10-09	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2008-06-03	B09B	Patent application refused [chapter 9.2 patent gazette]	Free format text: DE ACORDO COM O ARTIGO 37, SUGIRO O INDEFERIMENTO DO PRESENTE PEDIDO, TENDO POR BASE OS ARTIGOS 10, 24, 25 DA LEI 9.279 DE 14/05/1996.
2008-12-02	B12B	Appeal against refusal [chapter 12.2 patent gazette]