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BR9608147A - Método para descontaminação microbiana de plaquetas sanguìneas. - Google Patents

Método para descontaminação microbiana de plaquetas sanguìneas.

Info

Publication number
BR9608147A
BR9608147A BR9608147-3A BR9608147A BR9608147A BR 9608147 A BR9608147 A BR 9608147A BR 9608147 A BR9608147 A BR 9608147A BR 9608147 A BR9608147 A BR 9608147A
Authority
BR
Brazil
Prior art keywords
platelets
blood
microbial decontamination
fixative
period
Prior art date
Application number
BR9608147-3A
Other languages
English (en)
Inventor
Marjorie S Read
Arthur P Bode
Louis J Summaria
Original Assignee
Univ North Carolina
Univ East Carolina
Armour Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina, Univ East Carolina, Armour Pharma filed Critical Univ North Carolina
Publication of BR9608147A publication Critical patent/BR9608147A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • A61L2103/05—

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

Patente de Invenção:<B>"MéTODO PARA DESCONTAMINAçãO MICROBIANA DE PLAQUETAS SANGuìNEAS"<D>. Um método para a inativação de contaminantes microbiológicos em um preparado de plaquetas de sangue humano é descrito. O método compreende, primeiro, o fornecimento de plaquetas sang³íneas, particularmente plaquetas de sangue humano, que se suspeita estarem contaminadas com microorganismos. As plaquetas são, então, colocadas em contato com um fixador (de preferência, por meio da combinação das mesmas com uma solução de paraformaldeído a 1,8%^), durante um período de tempo suficiente para fixar as plaquetas (de prefer6encia, durante 45 minutos a 1 hora). Após a fixação, as plaquetas são, de preferência, lavadas e secas a fim de se produzir sang³íneas secas fixadas. A etapa de contato das plaquetas com um fixador é realizada durante um período de tempo sucifiente para matar alguns ou todos os microorganismos contaminantes.
BR9608147-3A 1995-04-19 1996-04-09 Método para descontaminação microbiana de plaquetas sanguìneas. BR9608147A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42489595A 1995-04-19 1995-04-19
PCT/US1996/005018 WO1996032969A1 (en) 1995-04-19 1996-04-09 Method for the microbial decontamination of blood platelets

Publications (1)

Publication Number Publication Date
BR9608147A true BR9608147A (pt) 1999-12-07

Family

ID=23684319

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9608147-3A BR9608147A (pt) 1995-04-19 1996-04-09 Método para descontaminação microbiana de plaquetas sanguìneas.

Country Status (18)

Country Link
EP (1) EP0821595B1 (pt)
JP (1) JPH11503936A (pt)
KR (1) KR100420799B1 (pt)
CN (1) CN1124160C (pt)
AR (1) AR001654A1 (pt)
AT (1) ATE181838T1 (pt)
AU (1) AU701723B2 (pt)
BR (1) BR9608147A (pt)
CA (1) CA2217298C (pt)
DE (1) DE69603174T2 (pt)
DK (1) DK0821595T3 (pt)
ES (1) ES2135224T3 (pt)
HU (1) HUP9802706A3 (pt)
IL (1) IL117722A (pt)
RU (1) RU2156138C2 (pt)
UA (1) UA56131C2 (pt)
WO (1) WO1996032969A1 (pt)
ZA (1) ZA962883B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7294455B2 (en) 2003-05-16 2007-11-13 The University Of North Carolina At Chapel Hill Fixed-dried platelets cross-linked to protein
JP4029298B2 (ja) * 2004-07-26 2008-01-09 大塚製薬株式会社 粘着性マイクロベシクルの除去方法
WO2014062651A1 (en) * 2012-10-18 2014-04-24 Cary Douglas D Stabilizer and preservative compositions and methods
EP2975345B1 (en) 2014-07-16 2019-01-02 LG Electronics Inc. Refrigerator door and manufacturing method of the same
CN105651568A (zh) * 2015-12-28 2016-06-08 西安交通大学第附属医院 一种血细胞分析仪质控品的制备方法
US20190328892A1 (en) * 2016-07-06 2019-10-31 Chuo University Therapeutic agent for ischemic disease
KR200492336Y1 (ko) 2018-11-14 2020-09-18 박영생 방화문의 투시창 프레임 구조

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0124596A4 (en) * 1982-11-12 1985-06-26 American Hospital Supply Corp Chemical sterilization of implantable biological tissue.
US5281392A (en) * 1986-03-10 1994-01-25 Rubinstein Alan I Method for disinfecting red blood cells, blood products, and corneas
WO1988009655A1 (en) * 1987-06-05 1988-12-15 Al Sioufi Habib Method and device for disinfecting biological fluids and container for same
DE3805459A1 (de) * 1988-02-22 1989-08-31 Biotest Pharma Gmbh Verfahren zur sterilisation von blut, plasma, blut- und plasmaderivaten, zellsuspensionen oder dgl.
DE69333924T2 (de) * 1992-05-29 2006-08-17 University Of North Carolina At Chapel Hill Im immobilisierten Zustand getrocknete pharmazeutisch verträgliche menschliche Blutplättchen

Also Published As

Publication number Publication date
ES2135224T3 (es) 1999-10-16
IL117722A0 (en) 1996-07-23
CA2217298C (en) 2005-09-27
ATE181838T1 (de) 1999-07-15
DE69603174T2 (de) 2000-03-09
CN1124160C (zh) 2003-10-15
HUP9802706A3 (en) 2001-08-28
UA56131C2 (uk) 2003-05-15
HUP9802706A2 (hu) 1999-03-29
DK0821595T3 (da) 2000-02-07
KR100420799B1 (ko) 2004-05-20
IL117722A (en) 2000-08-13
AU701723B2 (en) 1999-02-04
KR19990007857A (ko) 1999-01-25
DE69603174D1 (de) 1999-08-12
ZA962883B (en) 1996-10-15
AU5481596A (en) 1996-11-07
CA2217298A1 (en) 1996-10-24
RU2156138C2 (ru) 2000-09-20
EP0821595A1 (en) 1998-02-04
JPH11503936A (ja) 1999-04-06
CN1185117A (zh) 1998-06-17
WO1996032969A1 (en) 1996-10-24
MX9708027A (es) 1997-11-29
AR001654A1 (es) 1997-11-26
EP0821595B1 (en) 1999-07-07

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Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)