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BR9607095A - Composto composição farmacêutica e processos para fabricar e para administrar um composto - Google Patents

Composto composição farmacêutica e processos para fabricar e para administrar um composto

Info

Publication number
BR9607095A
BR9607095A BR9607095A BR9607095A BR9607095A BR 9607095 A BR9607095 A BR 9607095A BR 9607095 A BR9607095 A BR 9607095A BR 9607095 A BR9607095 A BR 9607095A BR 9607095 A BR9607095 A BR 9607095A
Authority
BR
Brazil
Prior art keywords
compound
administering
processes
making
pharmaceutical composition
Prior art date
Application number
BR9607095A
Other languages
English (en)
Inventor
Peter Robert Bernstein
Chris Allan Veale
Elwyn Peter Davies
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of BR9607095A publication Critical patent/BR9607095A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
BR9607095A 1995-02-03 1996-01-30 Composto composição farmacêutica e processos para fabricar e para administrar um composto BR9607095A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9502152.3A GB9502152D0 (en) 1995-02-03 1995-02-03 Proline derivatives
PCT/GB1996/000193 WO1996023812A1 (en) 1995-02-03 1996-01-30 Proline derivatives useful as inhibitors of human leukocyte elastase

Publications (1)

Publication Number Publication Date
BR9607095A true BR9607095A (pt) 1997-11-11

Family

ID=10769064

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9607095A BR9607095A (pt) 1995-02-03 1996-01-30 Composto composição farmacêutica e processos para fabricar e para administrar um composto

Country Status (23)

Country Link
US (4) US5686628A (pt)
EP (1) EP0808327A1 (pt)
JP (1) JPH10513173A (pt)
KR (1) KR19980701869A (pt)
CN (1) CN1172486A (pt)
AR (1) AR003922A1 (pt)
AU (1) AU704704B2 (pt)
BR (1) BR9607095A (pt)
CA (1) CA2209675A1 (pt)
CZ (1) CZ246697A3 (pt)
FI (1) FI973211A7 (pt)
GB (1) GB9502152D0 (pt)
HR (1) HRP960008A2 (pt)
HU (1) HUP9801991A3 (pt)
IL (1) IL117013A0 (pt)
NO (1) NO973539L (pt)
NZ (1) NZ300256A (pt)
PL (1) PL321680A1 (pt)
RU (1) RU2159249C2 (pt)
SK (1) SK105497A3 (pt)
TR (1) TR199700732T1 (pt)
WO (1) WO1996023812A1 (pt)
ZA (1) ZA96851B (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001500152A (ja) 1996-09-16 2001-01-09 ナイコメッド・アマーシャム・ピーエルシー 標識化エラスターゼ・インヒビター
HUP0100669A3 (en) * 1996-12-06 2001-12-28 Cortech Inc Denver Peptide derivatives as serine protease inhibitors, their use and pharmaceutical compositions comprising thereof
US5773430A (en) * 1997-03-13 1998-06-30 Research Foundation Of State University Of New York Serine proteinase inhibitory activity by hydrophobic tetracycline
US6423688B1 (en) 1997-07-31 2002-07-23 Athena Neurosciences, Inc. Dipeptide and related compounds which inhibit leukocyte adhesion mediated by VLA-4
US6583139B1 (en) 1997-07-31 2003-06-24 Eugene D. Thorsett Compounds which inhibit leukocyte adhesion mediated by VLA-4
US6489300B1 (en) 1997-07-31 2002-12-03 Eugene D. Thorsett Carbamyloxy compounds which inhibit leukocyte adhesion mediated by VLA-4
US7030114B1 (en) 1997-07-31 2006-04-18 Elan Pharmaceuticals, Inc. Compounds which inhibit leukocyte adhesion mediated by VLA-4
US6362341B1 (en) 1997-07-31 2002-03-26 Athena Neurosciences, Inc. Benzyl compounds which inhibit leukocyte adhesion mediated by VLA-4
US6492421B1 (en) 1997-07-31 2002-12-10 Athena Neurosciences, Inc. Substituted phenylalanine type compounds which inhibit leukocyte adhesion mediated by VLA-4
US6559127B1 (en) 1997-07-31 2003-05-06 Athena Neurosciences, Inc. Compounds which inhibit leukocyte adhesion mediated by VLA-4
US7232918B2 (en) * 2001-11-06 2007-06-19 Shell Oil Company Catalyst composition
US6544732B1 (en) * 1999-05-20 2003-04-08 Illumina, Inc. Encoding and decoding of array sensors utilizing nanocrystals
DE60031299T2 (de) 1999-12-16 2007-05-24 Dainippon Sumitomo Pharma Co., Ltd. Verfahren zur industriellen Herstellung von (Aminomethyl)trifluormethlcarbinol-Derivaten
CA2509363C (en) * 2002-12-12 2012-04-24 Novartis Ag Process for the synthesis of peptides containing a 4-hydroxy-proline substructure
WO2006016720A1 (ja) * 2004-08-11 2006-02-16 Dainippon Sumitomo Pharma Co., Ltd. 医薬化合物
WO2006025216A1 (ja) * 2004-08-31 2006-03-09 Dainippon Sumitomo Pharma Co., Ltd. 医薬結晶化合物
GB2438319B (en) * 2005-02-08 2009-03-04 Smith International Thermally stable polycrystalline diamond cutting elements and bits incorporating the same
EP3517531B1 (en) * 2016-09-23 2021-02-24 Kaken Pharmaceutical Co., Ltd. Method for producing (r)-5-(3,4-difluorophenyl)-5-[(3-methyl-2-oxopyridin-1(2h)-yl)methyl]imidazolidine-2,4-dione and intermediate for producing same
JP7672641B2 (ja) 2019-09-17 2025-05-08 メレオ バイオファーマ ４ リミテッド 移植片拒絶反応、閉塞性細気管支炎症候群、及び移植片対宿主病の治療に使用するためのアルベレスタット
MX2022012942A (es) 2020-04-16 2023-01-11 Mereo Biopharma 4 Ltd Metodos que involucran el inhibidor de la elastasa de neutrofilo alvelestat para el tratamiento de enfermedades respiratorias mediadas por deficiencia de alfa-1 antitripsina.
IL312002A (en) 2021-10-20 2024-06-01 Mereo Biopharma 4 Ltd Neutrophil elastase inhibitors for use in the treatment of fibrosis

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4277395A (en) * 1980-06-16 1981-07-07 Richardson-Merrell Inc. Novel enzyme inhibitors
DE3481913D1 (de) * 1983-04-27 1990-05-17 Ici America Inc Prolin-derivate.
US4518528A (en) * 1983-05-19 1985-05-21 Rasnick David W α Amino fluoro ketones
US4643991A (en) * 1984-12-18 1987-02-17 The University Of Kentucky Research Foundation Peptide elastase inhibitors and methods
GB8600263D0 (en) * 1985-01-22 1986-02-12 Ici America Inc Peptide derivatives
US5194588A (en) * 1985-01-22 1993-03-16 Ici Americas Inc. Aminoalcohol intermediates for peptide derivatives
US5055450A (en) * 1985-01-22 1991-10-08 Ici Americas Inc. Peptide derivatives
ZA86746B (en) * 1985-02-04 1986-09-24 Merrell Dow Pharma Novel peptidase inhibitors
CH672792A5 (pt) * 1985-02-19 1989-12-29 Sandoz Ag
IT1203971B (it) * 1987-04-24 1989-02-23 Roussel Maestretti Spa Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti
GB9402680D0 (en) * 1994-02-11 1994-04-06 Zeneca Ltd Pyrrolidine derivatives

Also Published As

Publication number Publication date
FI973211L (fi) 1997-08-01
PL321680A1 (en) 1997-12-22
US6054593A (en) 2000-04-25
HUP9801991A3 (en) 1999-06-28
JPH10513173A (ja) 1998-12-15
US5686628A (en) 1997-11-11
AU704704B2 (en) 1999-04-29
SK105497A3 (en) 1997-12-10
HRP960008A2 (en) 1998-04-30
KR19980701869A (ko) 1998-06-25
CN1172486A (zh) 1998-02-04
AU4494396A (en) 1996-08-21
WO1996023812A1 (en) 1996-08-08
NO973539L (no) 1997-10-01
ZA96851B (en) 1996-08-05
US5808097A (en) 1998-09-15
NZ300256A (en) 2000-01-28
CA2209675A1 (en) 1996-08-08
US6048889A (en) 2000-04-11
TR199700732T1 (xx) 1998-02-21
HUP9801991A2 (hu) 1999-02-01
GB9502152D0 (en) 1995-03-29
IL117013A0 (en) 1996-06-18
MX9705231A (es) 1997-10-31
AR003922A1 (es) 1998-09-30
CZ246697A3 (en) 1997-11-12
FI973211A0 (fi) 1997-08-01
FI973211A7 (fi) 1997-08-01
RU2159249C2 (ru) 2000-11-20
EP0808327A1 (en) 1997-11-26
NO973539D0 (no) 1997-08-01

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Legal Events

Date Code Title Description
FB36 Technical and formal requirements: requirement - article 36 of industrial property law
FA8 Dismissal: dismissal - article 36, par. 1 of industrial property law