BR9509173A - Novos androstanos para induzir efeitos hipotalámicos - Google Patents

Novos androstanos para induzir efeitos hipotalámicos

Info

Publication number: BR9509173A
Authority: BR; Brazil
Prior art keywords: androstans; induce; new; hypothalamic effects; hypothalamic
Prior art date: 1994-09-29

Application number

BR9509173A

Other languages

English (en)

Inventor

David L Berliner

William Nathan Adams

Clive L Jennings-White

Original Assignee

Pherin Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-09-29

Filing date

1995-09-29

Publication date

1997-11-25

1995-09-29 Application filed by Pherin Corp filed Critical Pherin Corp

1997-11-25 Publication of BR9509173A publication Critical patent/BR9509173A/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0007—Androstane derivatives not substituted in position 17
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0055—Estrane derivatives not substituted in position 17
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/002—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 13 (17)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
- C07J75/005—Preparation of steroids by cyclization of non-steroid compounds

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Steroid Compounds (AREA)

BR9509173A 1994-09-29 1995-09-29 Novos androstanos para induzir efeitos hipotalámicos BR9509173A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/316,435 US5969168A (en)	1991-01-07	1994-09-29	Androstanes for inducing hypothalamic effects
PCT/US1995/012538 WO1996010031A1 (en)	1994-09-29	1995-09-29	Novel androstanes for inducing hypothalamic effects

Publications (1)

Publication Number	Publication Date
BR9509173A true BR9509173A (pt)	1997-11-25

Family

ID=23229039

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9509173A BR9509173A (pt)	1994-09-29	1995-09-29	Novos androstanos para induzir efeitos hipotalámicos

Country Status (17)

Country	Link
US (1)	US5969168A (pt)
EP (1)	EP0783512A4 (pt)
JP (1)	JPH10509692A (pt)
KR (1)	KR970706296A (pt)
CN (1)	CN1057767C (pt)
AU (1)	AU702704B2 (pt)
BR (1)	BR9509173A (pt)
CA (1)	CA2199043A1 (pt)
CZ (1)	CZ92597A3 (pt)
FI (1)	FI971314L (pt)
HU (1)	HUT77665A (pt)
MX (1)	MX9702252A (pt)
NO (1)	NO971418L (pt)
NZ (1)	NZ294508A (pt)
PL (1)	PL319606A1 (pt)
RU (1)	RU2160740C2 (pt)
WO (1)	WO1996010031A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HUT74172A (en) *	1993-06-15	1996-11-28	Pherin Corp	Androstane steroids as neurochemical initilators of change in human hypothalamic function and pharmaceutical compositions containing them
US6066627A (en) *	1994-08-04	2000-05-23	Pherin Corporation	Steroids as neurochemical initiators of change in human blood levels of LH
WO1996010032A1 (en) *	1994-09-29	1996-04-04	Pherin Corporation	Novel estrenes for inducing hypothalamic effects
DE19509729A1 (de) *	1995-03-13	1996-09-19	Schering Ag	17-Difluormethylen-Estratriene
US5922699A (en) *	1996-06-07	1999-07-13	Pherin Corporation	19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function
BR9711812A (pt) *	1996-07-23	1999-08-24	Pherin Pharm Inc	EsterÄides como estimuladores neuroqu¡micos do ÄrgÆo vomeronasal para aliviar os sintomas de pms e ansiedade
US20030045514A1 (en) *	2001-05-03	2003-03-06	Louis Monti	17-Methyleneandrostan-3alpha-ol analogs as CRH inhibitors
US20040072814A1 (en)	2002-10-11	2004-04-15	Solvay Pharmaceuticals Gmbh	Method for obtaining a natural mixture of conjugated equine estrogens depleted in non-conjugated lipophilic compounds
AR041121A1 (es) *	2002-10-11	2005-05-04	Solvay Pharm Gmbh	Procedimiento para la obtencion de una mezcla natural de estrogenos conjugados
US8309539B2 (en)	2005-09-09	2012-11-13	Pherin Pharmaceuticals, Inc.	Acute treatment of social phobia
CN112778390B (zh) *	2021-01-22	2022-09-30	厦门欧瑞捷生物科技有限公司	一种雄烯酮的合成方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2846451A (en) *	1953-12-11	1958-08-05	Syntex Sa	Cyclopentanophenanthrene derivatives and process
US3043836A (en) *	1961-05-02	1962-07-10	Searle & Co	13beta-carboxy-17beta-hydroxy-10beta-methylgon-4-en-3-one, derivatives thereof and intermediates thereto
GB976215A (en) *	1962-03-15	1964-11-25	Searle & Co	Improvements in or relating to steroids
US3264327A (en) *	1962-07-27	1966-08-02	Syntex Corp	17alpha-fluoro-, 17beta-chlorofluoroacetoxy- and 17beta-methyl-delta4-and delta5-androstene derivatives
US3281436A (en) *	1964-08-05	1966-10-25	Abbott Lab	Process for making gem-difluorosteroids
US3413321A (en) *	1966-06-03	1968-11-26	Du Pont	Selected 17-fluoro-delta16 steroids
US3470216A (en) *	1966-11-29	1969-09-30	Du Pont	Selected 17,17-difluoro unsaturated androstanes
GB1175219A (en) *	1967-06-22	1969-12-23	Ici Ltd	3-Aminoalkoxycarbonylmethylene Steroid Derivatives
US3681490A (en) *	1969-07-22	1972-08-01	Nat Res Dev	Artificial insemination of pigs
DE2336432A1 (de) *	1973-07-13	1975-01-30	Schering Ag	3.17.18-trihydroxy-1.3.5(10)-oestratriene
FR2255313B1 (pt) *	1973-12-20	1976-10-08	Gole Jean
US4239681A (en) *	1974-04-15	1980-12-16	Richardson-Merrell Inc.	Androst-4-en-19-ols
US4071625A (en) *	1974-05-13	1978-01-31	Richardson-Merrell Inc.	19-Oxygenated-5α-androstanes for the enhancement of libido
US4022769A (en) *	1974-05-13	1977-05-10	Richardson-Merrell Inc.	Androst-4-en-19-ones
US4139617A (en) *	1974-05-13	1979-02-13	Richardson-Merrell Inc.	19-Oxygenated-androst-5-enes for the enhancement of libido
GB1550343A (en) *	1975-07-16	1979-08-15	Gist Brocades Nv	Androstane derivatives
DE2758549A1 (de) *	1977-12-23	1979-07-05	Schering Ag	Pharmazeutische zubereitung
US4133811A (en) *	1978-02-17	1979-01-09	E. R. Squibb & Sons, Inc.	13-Alkylthio (and arylthio)-11,17-epoxy-17-methyl-18-norandrostenes
US4212815A (en) *	1978-07-05	1980-07-15	E. I. Du Pont De Nemours And Company	Preparation of vinylene fluorides
US4425339A (en) *	1981-04-09	1984-01-10	Syntex (U.S.A.) Inc.	Treatment of menopausal symptoms
US4349474A (en) *	1981-07-27	1982-09-14	G. D. Searle & Co.	2-Cyanosteroids
US5155045A (en) *	1985-01-25	1992-10-13	Trustees Of The University Of Penn.	Use of male essence to alter female endocrine response
US4863911A (en) *	1986-08-04	1989-09-05	University Of Florida	Method for treating male sexual dysfunction
US4835147A (en) *	1987-05-06	1989-05-30	City Of Hope	Dehydroepiandrosterone therapy for ameleoration of prostate hypertrophy and sexual dysfunction
EP1236469A3 (en) *	1991-11-22	2004-09-01	Alcon Laboratories, Inc.	Angiostatic steroids
US5272134A (en) *	1992-03-24	1993-12-21	Erox Corporation	Fragrance compositions and other compositions which contain human pheromones
HUT74172A (en) *	1993-06-15	1996-11-28	Pherin Corp	Androstane steroids as neurochemical initilators of change in human hypothalamic function and pharmaceutical compositions containing them
WO1996010032A1 (en) *	1994-09-29	1996-04-04	Pherin Corporation	Novel estrenes for inducing hypothalamic effects

1994
- 1994-09-29 US US08/316,435 patent/US5969168A/en not_active Expired - Lifetime
1995
- 1995-09-29 CN CN95196354A patent/CN1057767C/zh not_active Expired - Fee Related
- 1995-09-29 BR BR9509173A patent/BR9509173A/pt unknown
- 1995-09-29 HU HU9800293A patent/HUT77665A/hu unknown
- 1995-09-29 CZ CZ97925A patent/CZ92597A3/cs unknown
- 1995-09-29 JP JP8512065A patent/JPH10509692A/ja active Pending
- 1995-09-29 FI FI971314A patent/FI971314L/fi unknown
- 1995-09-29 EP EP95935234A patent/EP0783512A4/en not_active Withdrawn
- 1995-09-29 CA CA002199043A patent/CA2199043A1/en not_active Abandoned
- 1995-09-29 PL PL95319606A patent/PL319606A1/xx unknown
- 1995-09-29 NZ NZ294508A patent/NZ294508A/xx unknown
- 1995-09-29 KR KR1019970702033A patent/KR970706296A/ko not_active Ceased
- 1995-09-29 AU AU37329/95A patent/AU702704B2/en not_active Ceased
- 1995-09-29 MX MX9702252A patent/MX9702252A/es unknown
- 1995-09-29 WO PCT/US1995/012538 patent/WO1996010031A1/en not_active Ceased
- 1995-09-29 RU RU97107006/04A patent/RU2160740C2/ru active
1997
- 1997-03-25 NO NO971418A patent/NO971418L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
KR970706296A (ko)	1997-11-03
RU2160740C2 (ru)	2000-12-20
NZ294508A (en)	1999-02-25
AU702704B2 (en)	1999-03-04
CZ92597A3 (en)	1997-09-17
EP0783512A1 (en)	1997-07-16
PL319606A1 (en)	1997-08-18
JPH10509692A (ja)	1998-09-22
AU3732995A (en)	1996-04-19
EP0783512A4 (en)	1998-09-02
HUT77665A (hu)	1998-07-28
CA2199043A1 (en)	1996-04-04
CN1166836A (zh)	1997-12-03
FI971314A0 (fi)	1997-03-27
FI971314A7 (fi)	1997-03-27
NO971418D0 (no)	1997-03-25
NO971418L (no)	1997-05-23
CN1057767C (zh)	2000-10-25
WO1996010031A1 (en)	1996-04-04
US5969168A (en)	1999-10-19
MX9702252A (es)	1997-06-28
FI971314L (fi)	1997-03-27

Publication	Publication Date	Title
FI951417A7 (fi)	1995-09-30	Bifenyylijohdannaiset
FI972194L (fi)	1997-05-22	Uusia bentsyylipyrimidiinejä
FI942119A0 (fi)	1994-05-06	Anordning i en gasblandare
FI953710L (fi)	1996-02-05	Uusia pyrrolokarbatsoleja
BR9509173A (pt)	1997-11-25	Novos androstanos para induzir efeitos hipotalámicos
BR9509098A (pt)	1998-07-14	Novos estrenos para induzir efeitos hipotalâmicos
ATA210294A (de)	1995-12-15	Dämmatte
FI1516U1 (fi)	1994-09-20	Foerpackning foer i stapel anordnade smaoark
AR016434A1 (es)	2001-07-04	Procedimiento para preparar clorobenzoxazoles
FI962961A0 (fi)	1996-07-24	Telebetalningssystem i realtid
ES1029183Y (es)	1995-10-16	Estructura para toldos
KR950031093U (ko)	1995-11-22	단열구조체
FI941032A0 (fi)	1994-03-04	Saett att oeverfoera en sjoecontainer
SE9404519D0 (sv)	1994-12-27	New composition
FI940632A0 (fi)	1994-02-11	Kombinerat braensle- och ellaos
KR960012685U (ko)	1996-04-17	씨모오스 구조
KR960011162U (ko)	1996-04-15	단열재 고정기구
KR960011163U (ko)	1996-04-15	단열재 고정기구
KR960016646U (ko)	1996-06-17	포크가 형성된 과도
SE9403712D0 (sv)	1994-10-31	Trappnos
KR950026997U (ko)	1995-10-16	단열구조체
KR960015930U (ko)	1996-05-17	튜너의 충격방지 접지구조
BR7400265U (pt)	1995-10-24	Disposição introduzida em caneta
BR9400161A (pt)	1994-05-31	Luva para natação
SE9402421D0 (sv)	1994-07-08	New use

Legal Events

Date	Code	Title	Description
2005-03-29	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]