BR9509019A - Processo para fabricar unidades de dosagem farmacêutica e comprimido isento de solventes orgânicos - Google Patents

Processo para fabricar unidades de dosagem farmacêutica e comprimido isento de solventes orgânicos

Info

Publication number: BR9509019A
Authority: BR; Brazil
Prior art keywords: pharmaceutical dosage; pct; dosage units; organic solvents; manufacturing pharmaceutical
Prior art date: 1994-09-22

Application number

BR9509019A

Other languages

English (en)

Other versions

BR9509019B1 (pt

Inventor

Pieter De Haan

Jocominus Antonius Ma Zwinkels

Original Assignee

Akzo Nobel Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-09-22

Filing date

1995-09-19

Publication date

1997-12-30

1995-09-19 Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv

1997-12-30 Publication of BR9509019A publication Critical patent/BR9509019A/pt

2009-01-13 Publication of BR9509019B1 publication Critical patent/BR9509019B1/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Endocrinology (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Reproductive Health (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Diabetes (AREA)
Gynecology & Obstetrics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Steroid Compounds (AREA)
Medical Preparation Storing Or Oral Administration Devices (AREA)
Cosmetics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

BRPI9509019-3A 1994-09-22 1995-09-19 comprimido isento de solventes orgÂnicos. BR9509019B1 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP94202728		1994-09-22
PCT/EP1995/003692 WO1996009056A1 (en)	1994-09-22	1995-09-19	Process of making dosage units by wet granulation

Publications (2)

Publication Number	Publication Date
BR9509019A true BR9509019A (pt)	1997-12-30
BR9509019B1 BR9509019B1 (pt)	2009-01-13

Family

ID=8217217

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI9509019-3A BR9509019B1 (pt)	1994-09-22	1995-09-19	comprimido isento de solventes orgÂnicos.

Country Status (22)

Country	Link
US (1)	US5916593A (pt)
EP (1)	EP0782449B1 (pt)
JP (1)	JP4334616B2 (pt)
KR (1)	KR100384264B1 (pt)
CN (1)	CN1101681C (pt)
AT (1)	ATE236639T1 (pt)
AU (1)	AU700645B2 (pt)
BR (1)	BR9509019B1 (pt)
CA (1)	CA2200754C (pt)
CZ (1)	CZ289081B6 (pt)
DE (1)	DE69530308T2 (pt)
DK (1)	DK0782449T3 (pt)
ES (1)	ES2196079T3 (pt)
FI (1)	FI118791B (pt)
HU (1)	HU226619B1 (pt)
MX (1)	MX9702162A (pt)
NO (1)	NO311492B1 (pt)
NZ (1)	NZ293606A (pt)
PL (1)	PL181406B1 (pt)
PT (1)	PT782449E (pt)
RU (1)	RU2166936C2 (pt)
WO (1)	WO1996009056A1 (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0955048A1 (en) *	1998-03-12	1999-11-10	Akzo Nobel N.V.	Making dosage units using low shear granulation
IL128818A0 (en) *	1998-03-12	2000-01-31	Akzo Nobel Nv	Making dosage units using low shear granulation
AU2669700A (en) *	1999-02-24	2000-09-14	Akzo Nobel N.V.	Pharmaceutical compositions containing a crystalline form of the progestagen-(17alpha)-17-hydroxy-11-methylene-19-nor-pregna- 4,15-dien-20-yn-3-one (org 30659) and lactose
KR101019361B1 (ko) *	1999-08-31	2011-03-07	바이엘 쉐링 파마 악티엔게젤샤프트	피임약으로서의 사용을 위한 에티닐에스트라디올과드로스피렌온의 약학적 조합
US6787531B1 (en) *	1999-08-31	2004-09-07	Schering Ag	Pharmaceutical composition for use as a contraceptive
EP1216713A1 (en) *	2000-12-20	2002-06-26	Schering Aktiengesellschaft	Compositions of estrogen-cyclodextrin complexes
US20030027848A1 (en) *	2001-06-15	2003-02-06	Anne Billotte	Stabilized formulations
ATE243028T1 (de) *	2001-07-11	2003-07-15	Applied Pharma Res	Fettlösliche substanzen enthaltende granulate und verfahren zu ihrer herstellung
DE10159120B4 (de) *	2001-12-01	2006-08-17	Lts Lohmann Therapie-Systeme Ag	Steroidhormonhaltige transdermale therapeutische Systeme enthaltend Propylenglycolmonocaprylat und seine Verwendung
GB0209265D0 (en)	2002-04-23	2002-06-05	Novartis Ag	Organic compounds
TW200403075A (en) *	2002-05-29	2004-03-01	Akzo Nobel Nv	Progestagenic dosage units
EP1790347B1 (en)	2002-12-20	2014-12-24	F. Hoffmann-La Roche AG	High dose ibandronate formulation
RU2228747C1 (ru) *	2003-03-03	2004-05-20	Открытое акционерное общество "Щелковский витаминный завод"	Антиангинальное средство пролонгированного действия
CZ298224B6 (cs) *	2003-04-29	2007-07-25	Pliva Istrazivanje I Razvoj D.O.O.	Farmaceutická kompozice obsahující jako úcinnou látku ribavirin a zpusob její výroby
WO2005030175A1 (en) *	2003-09-29	2005-04-07	Novo Nordisk Femcare Ag	Hrt formulations
WO2005030176A1 (en)	2003-09-29	2005-04-07	Novo Nordisk Femcare Ag	Improved stability of progestogen formulations
JP4412963B2 (ja) *	2003-10-10	2010-02-10	旭有機材工業株式会社	バルブ用樹脂製部材
US20070202179A1 (en) *	2004-04-09	2007-08-30	FAULKNER Patrick	Low Dose Pharmaceutical Products
US7846466B2 (en) *	2004-06-10	2010-12-07	Northwestern University	Biodegradable scaffolds and uses thereof
MX2007004973A (es) *	2004-10-25	2007-06-14	Japan Tobacco Inc	Formulacion solida con solubilidad y estabilidad mejoradas y metodo para producir la formulacion.
AU2006206359B2 (en) *	2005-01-21	2011-03-31	Allergan Pharmaceuticals International Limited	A tetracycline metal complex in a solid dosage form
KR20070094666A (ko) *	2005-02-25	2007-09-20	에프. 호프만-라 로슈 아게	약제 물질 분산성이 향상된 정제
US8617597B2 (en)	2006-07-06	2013-12-31	Bayer Intellectual Property Gmbh	Pharmaceutical composition containing a tetrahydrofolic acid
CN101489563A (zh) *	2006-07-06	2009-07-22	拜耳先灵医药股份有限公司	用于避孕和预防先天性畸形风险的药物制剂
US20090269403A1 (en) *	2008-04-24	2009-10-29	Shaked Ze Ev	Oral contraceptive dosage forms and methods of making such dosage forms
AU2009279521A1 (en) *	2008-08-08	2010-02-11	Mcneil-Ppc, Inc.	Use of sucralose as a granulating agent
ES2391132T3 (es) *	2008-10-09	2012-11-21	Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi	Uso de disolventes orgánicos en la granulación húmeda de moxifloxacino
US8945615B2 (en) *	2009-02-17	2015-02-03	Mylan Pharmaceuticals Inc.	Controlled release budesonide minitablets
US8945616B2 (en) *	2009-02-17	2015-02-03	Mylan Pharmaceuticals Inc.	Controlled release budesonide minitablets
JP2017001989A (ja) *	2015-06-11	2017-01-05	ニプロ株式会社	医薬組成物の製造方法及び医薬組成物
JP6759478B2 (ja) *	2019-02-13	2020-09-23	富士製薬工業株式会社	経口固形組成物、その製造方法、及びその製造方法によって得られた経口用錠剤

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3969502A (en) *	1972-04-14	1976-07-13	Schering Aktiengesellschaft	Method for contraception by the administration of sequential contraceptive preparations
GB2192128A (en) *	1986-07-03	1988-01-06	Fa Ez Khan	Production of pharmaceutical unit dosage forms
US4956182A (en) *	1989-03-16	1990-09-11	Bristol-Myers Company	Direct compression cholestyramine tablet and solvent-free coating therefor
US5098714A (en) *	1989-11-16	1992-03-24	Alza Corporation	Osmotic, oral dosage form for fertility control
US5200197A (en) *	1989-11-16	1993-04-06	Alza Corporation	Contraceptive pill
IE62665B1 (en) *	1990-12-17	1995-02-22	Akzo Nv	Contraceptive regimen
IE71202B1 (en) *	1990-12-17	1997-02-12	Akzo Nv	Progestagen-only contraceptive
IE67345B1 (en) *	1991-03-12	1996-03-20	Akzo Nv	Low dose dry pharmaceutical preparations
DE4229820C2 (de) *	1992-09-07	1998-12-03	Jenapharm Gmbh	Pharmazeutische Zubereitung auf Gestagen-Basis
CA2151260A1 (en) *	1993-02-23	1994-09-01	Pankaj B. Gala	A process for the preparation of substantially alcohol free pharmaceutical compositions
DE69418744T2 (de) *	1993-03-05	1999-11-11	Akzo Nobel N.V., Arnheim/Arnhem	Verwendung von Pregnanderivaten zur Behandlung von Tumoren
NL9301562A (nl) *	1993-09-09	1995-04-03	Saturnus Ag	Preparaat voor substitutietherapie.
ZA939565B (en) *	1993-12-21	1994-08-11	Applied Analytical Ind Inc	Method for preparing low dose pharmaceutical products.

1995
- 1995-09-19 KR KR1019970701723A patent/KR100384264B1/ko not_active Expired - Fee Related
- 1995-09-19 AU AU36082/95A patent/AU700645B2/en not_active Ceased
- 1995-09-19 AT AT95933401T patent/ATE236639T1/de not_active IP Right Cessation
- 1995-09-19 CN CN95195823A patent/CN1101681C/zh not_active Expired - Fee Related
- 1995-09-19 CA CA002200754A patent/CA2200754C/en not_active Expired - Fee Related
- 1995-09-19 JP JP51058896A patent/JP4334616B2/ja not_active Expired - Fee Related
- 1995-09-19 BR BRPI9509019-3A patent/BR9509019B1/pt not_active IP Right Cessation
- 1995-09-19 RU RU97106339/14A patent/RU2166936C2/ru not_active IP Right Cessation
- 1995-09-19 ES ES95933401T patent/ES2196079T3/es not_active Expired - Lifetime
- 1995-09-19 HU HU9800154A patent/HU226619B1/hu not_active IP Right Cessation
- 1995-09-19 WO PCT/EP1995/003692 patent/WO1996009056A1/en not_active Ceased
- 1995-09-19 MX MX9702162A patent/MX9702162A/es not_active IP Right Cessation
- 1995-09-19 NZ NZ293606A patent/NZ293606A/en not_active IP Right Cessation
- 1995-09-19 DK DK95933401T patent/DK0782449T3/da active
- 1995-09-19 DE DE69530308T patent/DE69530308T2/de not_active Expired - Lifetime
- 1995-09-19 PT PT95933401T patent/PT782449E/pt unknown
- 1995-09-19 EP EP95933401A patent/EP0782449B1/en not_active Expired - Lifetime
- 1995-09-19 PL PL95319373A patent/PL181406B1/pl not_active IP Right Cessation
- 1995-09-19 US US08/793,976 patent/US5916593A/en not_active Expired - Fee Related
- 1995-09-19 CZ CZ1997899A patent/CZ289081B6/cs not_active IP Right Cessation
1997
- 1997-03-20 FI FI971172A patent/FI118791B/fi active
- 1997-03-21 NO NO19971361A patent/NO311492B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
PL319373A1 (en)	1997-08-04
PL181406B1 (pl)	2001-07-31
JPH10505846A (ja)	1998-06-09
RU2166936C2 (ru)	2001-05-20
CA2200754C (en)	2008-04-15
CZ289081B6 (cs)	2001-10-17
DK0782449T3 (da)	2003-08-04
HK1002172A1 (en)	1998-08-07
HUT77611A (hu)	1998-06-29
MX9702162A (es)	1997-06-28
WO1996009056A1 (en)	1996-03-28
DE69530308T2 (de)	2003-10-16
KR970706001A (ko)	1997-11-03
BR9509019B1 (pt)	2009-01-13
HU226619B1 (en)	2009-04-28
FI971172L (fi)	1997-03-20
DE69530308D1 (de)	2003-05-15
CZ89997A3 (en)	1997-09-17
NO311492B1 (no)	2001-12-03
NO971361D0 (no)	1997-03-21
AU700645B2 (en)	1999-01-14
KR100384264B1 (ko)	2003-08-30
EP0782449A1 (en)	1997-07-09
CN1101681C (zh)	2003-02-19
EP0782449B1 (en)	2003-04-09
NZ293606A (en)	1998-06-26
NO971361L (no)	1997-05-21
FI118791B (fi)	2008-03-31
FI971172A0 (fi)	1997-03-20
US5916593A (en)	1999-06-29
ATE236639T1 (de)	2003-04-15
PT782449E (pt)	2003-07-31
CN1161650A (zh)	1997-10-08
ES2196079T3 (es)	2003-12-16
AU3608295A (en)	1996-04-09
CA2200754A1 (en)	1996-03-28
JP4334616B2 (ja)	2009-09-30

Publication	Publication Date	Title
BR9509019A (pt)	1997-12-30	Processo para fabricar unidades de dosagem farmacêutica e comprimido isento de solventes orgânicos
ATE260646T1 (de)	2004-03-15	Schnell zerfallende orale dosierungsform
AP1637A (en)	2006-07-17	Celecoxib compositions.
BR9406363A (pt)	1996-02-27	Composiçao farmacêutica processo para a preparaçao da mesma uso da mesma e processo para o tratamento de doenças relacionadas com o ácido gástrico
SE9504661D0 (sv)	1995-12-22	New compounds
BG105568A (en)	2002-01-31	Pharmaceutical compositions for modified release of an insulin sensitiser and another antidiabetic agent
BR9811980A (pt)	2000-08-15	Comprimidos de metilcelulose de rápida desintegração
NO972324L (no)	1997-07-21	Orale blandinger inneholdende Ondansetron
CO4290417A1 (es)	1996-04-17	Nuevas benzoilguanidinas como medicamentos y su preparacion .
NO982902D0 (no)	1998-06-22	FremgangsmÕte og preparatsett for Õ hindre befruktning hos hunn-pattedyr som omfatter en kombinasjon av gestagen og °strogen
PT758241E (pt)	2002-10-31	Utilizacao de certos derivados de acido metanobisfosfonico para impedir o desprendimento de proteses e a migracao de proteses
ATE272628T1 (de)	2004-08-15	Substituierte gamma-phenyl-delta-lactone und deren analoge, und ihre verwendungen
AU2002231889A1 (en)	2002-08-06	Halogenated composition, method for preparing same and uses thereof
FI972434A0 (fi)	1997-06-06	Lamotrigiiniä sisältävä farmaseuttinen koostumus
BR9504573A (pt)	1997-02-25	Formulaçao farmaceutica adequada para fabricaçao de tabletes dispersiveis por compressao direta tablete de cefaclor dispersivel e processo para fabricaçao de um tablete dispersivel contendo cefaclor
ES2148493T3 (es)	2000-10-16	Nuevos compuestos con efecto analgesico y anestesico local.
ES2110258T3 (es)	1998-02-01	Derivados de 1,3,5(10)-estratrieno activos por via oral.
SE9504662D0 (sv)	1995-12-22	New compounds
DK0749304T3 (da)	1999-08-02	Retardtablet med et indhold af diclofenac-Na
BG103512A (en)	2000-07-31	Substituted pyramidine compounds and their application
DK0862454T3 (da)	2002-12-30	CTLA-8 i kombination med G-CSF eller med G-CSF og IL-6 og anvendelse af CTLA-8 til behandling af infektioner
EE9900346A (et)	2000-02-15	Viljatusevastane ja viljastumisvõimet tõstev ravim
ES2104507A1 (es)	1997-10-01	Empleo de hidrolizado de gelatina para preparar una composicion farmaceutica destinada a la prevencion y tratamiento de la displasia de cadera en perros.

Legal Events

Date	Code	Title	Description
2002-02-13	FB36	Technical and formal requirements: requirement - article 36 of industrial property law
2005-02-15	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2008-01-22	B25A	Requested transfer of rights approved	Owner name: N.V. ORGANON (NL) Free format text: TRANSFERIDO DE: AKZO NOBEL N.V.
2008-04-15	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2009-02-25	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 25/02/2009, OBSERVADAS AS CONDICOES LEGAIS.
2012-01-17	B24C	Patent annual fee: request for for restoration	Free format text: REFERENTE A 16A ANUIDADE.
2013-04-30	B21F	Lapse acc. art. 78, item iv - on non-payment of the annual fees in time	Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 2141 DE 17/01/2012 E AO NAO RECOLHIMENTO DA 17A ANUIDADE.