BR9508436A - Dihidro benzofurando e compostos correlacionados úteis como agentes anti-inflamatórios - Google Patents
Dihidro benzofurando e compostos correlacionados úteis como agentes anti-inflamatóriosInfo
- Publication number
- BR9508436A BR9508436A BR9508436A BR9508436A BR9508436A BR 9508436 A BR9508436 A BR 9508436A BR 9508436 A BR9508436 A BR 9508436A BR 9508436 A BR9508436 A BR 9508436A BR 9508436 A BR9508436 A BR 9508436A
- Authority
- BR
- Brazil
- Prior art keywords
- unsubstituted
- hydrogen
- benzofilling
- dihydro
- branched
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 229940121363 anti-inflammatory agent Drugs 0.000 title 1
- 239000002260 anti-inflammatory agent Substances 0.000 title 1
- 230000002596 correlated effect Effects 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 125000004429 atom Chemical group 0.000 abstract 2
- 206010061218 Inflammation Diseases 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical class [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 229910052717 sulfur Chemical group 0.000 abstract 1
- 239000011593 sulfur Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28089294A | 1994-07-27 | 1994-07-27 | |
| US08/481,727 US5656661A (en) | 1994-07-27 | 1995-06-07 | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
| PCT/US1995/009109 WO1996003396A1 (en) | 1994-07-27 | 1995-07-19 | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9508436A true BR9508436A (pt) | 1998-07-14 |
Family
ID=26960588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9508436A BR9508436A (pt) | 1994-07-27 | 1995-07-19 | Dihidro benzofurando e compostos correlacionados úteis como agentes anti-inflamatórios |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0773939B1 (pt) |
| JP (1) | JPH10506615A (pt) |
| CN (1) | CN1191243C (pt) |
| AT (1) | ATE385496T1 (pt) |
| AU (1) | AU704085B2 (pt) |
| BR (1) | BR9508436A (pt) |
| CA (1) | CA2196054C (pt) |
| ES (1) | ES2301161T3 (pt) |
| IL (1) | IL114698A (pt) |
| NZ (1) | NZ290080A (pt) |
| WO (1) | WO1996003396A1 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5821250A (en) * | 1996-02-01 | 1998-10-13 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
| US5750543A (en) * | 1996-02-01 | 1998-05-12 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
| US5686471A (en) * | 1996-02-01 | 1997-11-11 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
| US5684031A (en) * | 1996-02-01 | 1997-11-04 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
| US5618835A (en) * | 1996-02-01 | 1997-04-08 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
| US5672620A (en) * | 1996-02-01 | 1997-09-30 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
| FR2744452B1 (fr) * | 1996-02-06 | 1998-03-06 | Cird Galderma | Composes biaryles heterocycliques, compositions pharmaceutiques et cosmetiques les contenant et utilisations |
| FR2754260B1 (fr) * | 1996-10-04 | 1998-10-30 | Adir | Nouveaux derives substitues de biphenyle ou de phenylpyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US5985930A (en) * | 1996-11-21 | 1999-11-16 | Pasinetti; Giulio M. | Treatment of neurodegenerative conditions with nimesulide |
| EP2641903B1 (de) | 2012-03-19 | 2014-10-22 | Symrise AG | Dihydrobenzofuran-Derivate als Riech- und/oder Aromastoffe |
| KR101592560B1 (ko) * | 2013-06-21 | 2016-02-05 | 제주대학교 산학협력단 | 신규 플라보노이드 및 그 용도 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3551456A (en) * | 1968-04-18 | 1970-12-29 | Universal Oil Prod Co | Acetyl derivatives of substituted chromans and coumarans |
| FR2370472A2 (fr) * | 1976-11-10 | 1978-06-09 | Continental Pharma | Amino-alcool heterocyclique, son sel et son procede de preparation |
| EP0026593A1 (en) * | 1979-09-15 | 1981-04-08 | Pfizer Limited | Bicyclic keto- and amino- acids, esters and amides and pharmaceutical compositions thereof |
| GR81257B (pt) * | 1982-12-04 | 1984-12-11 | Lilly Industries Ltd | |
| DE3460315D1 (en) * | 1983-02-19 | 1986-08-28 | Beecham Group Plc | Benzofuran and benzothiophene-carboxylic-acid derivatives |
| FI842738L (fi) * | 1983-07-14 | 1985-01-15 | Syntex Inc | Aroylbenzofuran- och benzotiofenaettik- och propionsyror. |
| US4613611A (en) * | 1983-10-14 | 1986-09-23 | American Cyanamid Company | Method of treating diabetes mellitus using arylglyoxals |
| AU4261285A (en) * | 1984-06-01 | 1985-12-05 | Tokyo Tanabe Company Limited | 1-propanone derivatives |
| FR2613365B1 (fr) * | 1987-04-01 | 1989-07-28 | Adir | Nouveaux derives de l'amino tetrahydro-5, 6, 7, 8 naphto (2, 3b) furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2613364B1 (fr) * | 1987-04-01 | 1989-06-09 | Adir | Nouvelles amines tricycliques derivees du tetrahydro-5, 6, 7, 8 naphto (2, 3b) dihydro-2, 3 furanne, et du tetrahydro-6, 7, 8, 9 5h-benzocyclohepta (2, 3b) dihydro-2, 3 furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
| US4849428A (en) * | 1987-11-23 | 1989-07-18 | The Procter & Gamble Company | Cyclic anti-inflammatory derivatives of di-tert-butylphenol compounds, compositions and use |
| IL88674A0 (en) * | 1987-12-18 | 1989-07-31 | Norwich Eaton Pharma | Preparation of certain substituted aromatic compounds |
| GB8906166D0 (en) * | 1989-03-17 | 1989-05-04 | Pfizer Ltd | Therapeutic agents |
| JP2808460B2 (ja) * | 1989-11-16 | 1998-10-08 | 大正製薬株式会社 | イミダゾール誘導体 |
| JPH03215485A (ja) * | 1990-01-11 | 1991-09-20 | Taisho Pharmaceut Co Ltd | ベンゾチエニルイミダゾール誘導体 |
| TW197435B (pt) * | 1990-11-22 | 1993-01-01 | Takeda Pharm Industry Co Ltd | |
| JPH06263733A (ja) * | 1993-01-14 | 1994-09-20 | Sankyo Co Ltd | ベンゼン誘導体 |
-
1995
- 1995-07-19 JP JP8505840A patent/JPH10506615A/ja active Pending
- 1995-07-19 WO PCT/US1995/009109 patent/WO1996003396A1/en not_active Ceased
- 1995-07-19 ES ES95926314T patent/ES2301161T3/es not_active Expired - Lifetime
- 1995-07-19 CN CNB951948911A patent/CN1191243C/zh not_active Expired - Fee Related
- 1995-07-19 CA CA002196054A patent/CA2196054C/en not_active Expired - Fee Related
- 1995-07-19 NZ NZ290080A patent/NZ290080A/en unknown
- 1995-07-19 AU AU30711/95A patent/AU704085B2/en not_active Ceased
- 1995-07-19 EP EP95926314A patent/EP0773939B1/en not_active Expired - Lifetime
- 1995-07-19 BR BR9508436A patent/BR9508436A/pt not_active Application Discontinuation
- 1995-07-19 AT AT95926314T patent/ATE385496T1/de not_active IP Right Cessation
- 1995-07-24 IL IL11469895A patent/IL114698A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2301161T3 (es) | 2008-06-16 |
| CA2196054A1 (en) | 1996-02-08 |
| NZ290080A (en) | 1999-04-29 |
| WO1996003396A1 (en) | 1996-02-08 |
| ATE385496T1 (de) | 2008-02-15 |
| CA2196054C (en) | 2001-04-17 |
| EP0773939B1 (en) | 2008-02-06 |
| CN1191243C (zh) | 2005-03-02 |
| IL114698A (en) | 2001-03-19 |
| AU704085B2 (en) | 1999-04-15 |
| AU3071195A (en) | 1996-02-22 |
| JPH10506615A (ja) | 1998-06-30 |
| IL114698A0 (en) | 1995-11-27 |
| CN1156993A (zh) | 1997-08-13 |
| EP0773939A1 (en) | 1997-05-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Transfer |
Free format text: VANDERBILT UNIVERSITY (US) |
|
| EG | Technical examination (opinion): publication of technical examination (opinion) | ||
| FC | Decision: refusal |