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BR9406564A - Processo para a separação de uma enzima de uma solução aquosa - Google Patents

Processo para a separação de uma enzima de uma solução aquosa

Info

Publication number
BR9406564A
BR9406564A BR9406564-0A BR9406564A BR9406564A BR 9406564 A BR9406564 A BR 9406564A BR 9406564 A BR9406564 A BR 9406564A BR 9406564 A BR9406564 A BR 9406564A
Authority
BR
Brazil
Prior art keywords
enzyme
aqueous solution
separation
separating
recovering
Prior art date
Application number
BR9406564-0A
Other languages
English (en)
Inventor
Birgitte Mahler Nilsson
Mads Aage Laustsen
Christine Pahle
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8093052&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9406564(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of BR9406564A publication Critical patent/BR9406564A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/816—Enzyme separation or purification by solubility

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

Patente de Invenção "PROCESSO PARA A SEPARAçãO DE UMA ENZIMA DE UMA SOLUçãO AQUOSA". A presente invenção se refere a um processo de separação de uma enzima de uma solução aquosa compreendendo esta enzima na mistura com outras proteínas, e à recuperação da enzima desejada na forma cristalina.
BR9406564-0A 1993-04-02 1994-03-29 Processo para a separação de uma enzima de uma solução aquosa BR9406564A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK93396A DK39693D0 (da) 1993-04-02 1993-04-02 Enzym
PCT/DK1994/000132 WO1994022903A1 (en) 1993-04-02 1994-03-29 Separation of proteins

Publications (1)

Publication Number Publication Date
BR9406564A true BR9406564A (pt) 1999-08-31

Family

ID=8093052

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9406564-0A BR9406564A (pt) 1993-04-02 1994-03-29 Processo para a separação de uma enzima de uma solução aquosa

Country Status (13)

Country Link
US (1) US5719048A (pt)
EP (1) EP0691982B2 (pt)
JP (1) JP3542601B2 (pt)
KR (1) KR960701082A (pt)
CN (1) CN1039244C (pt)
AT (1) ATE171189T1 (pt)
AU (1) AU6424294A (pt)
BR (1) BR9406564A (pt)
DE (1) DE69413389T2 (pt)
DK (2) DK39693D0 (pt)
ES (1) ES2124400T3 (pt)
FI (1) FI954648A7 (pt)
WO (1) WO1994022903A1 (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000506145A (ja) * 1996-03-08 2000-05-23 ノボ ノルディスク アクティーゼルスカブ 硫化塩によるタンパク質の結晶化
US6031082A (en) * 1996-03-14 2000-02-29 Novo Nordisk A/S Increased yields of a crystallized protein by using a solid adsorption material
US5914141A (en) * 1997-03-11 1999-06-22 Alfacel S.A. Easy peeling wiener casings via use of enzymes
US6140475A (en) * 1997-04-11 2000-10-31 Altus Biologics Inc. Controlled dissolution crosslinked protein crystals
US20010046493A1 (en) * 2000-02-24 2001-11-29 Alex Margolin Lipase-containing composition and methods of use thereof
US7142464B2 (en) * 2003-04-29 2006-11-28 Saifun Semiconductors Ltd. Apparatus and methods for multi-level sensing in a memory array
JP5032300B2 (ja) 2004-03-22 2012-09-26 アボット プロダクツ ゲゼルシャフト ミット ベシュレンクテル ハフツング 界面活性剤を含有している、リパーゼを含有する生成物の、とりわけパンクレアチンの経口医薬組成物
US7823635B2 (en) * 2004-08-23 2010-11-02 Halliburton Energy Services, Inc. Downhole oil and water separator and method
WO2006044529A1 (en) * 2004-10-14 2006-04-27 Altus Pharmaceuticals Inc. Compositions containing lipase; protease and amylase for treating pancreatic insufficiency
EP2278002B1 (en) 2005-07-29 2017-07-12 Abbott Laboratories GmbH Pancreatin with reduced viral content
US11266607B2 (en) 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US20100196344A1 (en) * 2005-10-14 2010-08-05 Cystic Fibrosis Foundation Therapeutics, Inc. Compositions and methods for treating pancreatic insufficiency
US10072256B2 (en) 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
BRPI0721103A2 (pt) 2006-12-21 2014-03-04 Novozymes As Lipase, método de determinação do desempenho da digestão in vitro de uma lipase em comparação com uma lipase de referência, uso de uma lipase ou de uma mistura de lipases, composição farmacêutica, e, método para o tratamento de doença
WO2011000924A1 (en) 2009-07-03 2011-01-06 Abbott Products Gmbh Spray-dried amylase, pharmaceutical preparations comprising the same and use
CN104769375B (zh) * 2012-10-05 2017-06-23 阿塞里克股份有限公司 包括水分配器的制冷器
WO2015181118A1 (en) 2014-05-27 2015-12-03 Novozymes A/S Methods for producing lipases
CN106459939A (zh) 2014-05-27 2017-02-22 诺维信公司 脂肪酶变体以及编码它们的多核苷酸
MX388061B (es) 2014-12-05 2025-03-19 Novozymes As Variantes de lipasa y polinucleotidos que las codifican.
CN107922930A (zh) 2015-07-01 2018-04-17 诺维信公司 减少气味的方法
EP3950939A3 (en) 2015-07-06 2022-06-08 Novozymes A/S Lipase variants and polynucleotides encoding same
CN108431217B (zh) 2015-12-01 2022-06-21 诺维信公司 用于产生脂肪酶的方法
EP3485008B1 (en) 2016-07-18 2024-01-31 Novozymes A/S Lipase variants, polynucleotides encoding same and the use thereof
KR102775859B1 (ko) * 2016-12-23 2025-03-06 아를라 푸즈 에이엠비에이 신규 베타-락토글로불린 제제의 제조 및 관련 방법, 용도 및 식료품
US11078445B2 (en) 2017-05-05 2021-08-03 Novozymes A/S Compositions comprising lipase and sulfite
EP3645692B1 (en) 2017-06-30 2025-12-31 Novozymes A/S ENZYMATIC SUSPENSION COMPOSITION
US11725197B2 (en) 2017-12-04 2023-08-15 Novozymes A/S Lipase variants and polynucleotides encoding same
JP7610411B2 (ja) 2018-06-27 2025-01-08 アーラ フーズ エイエムビーエイ Ｂｌｇベースのインスタント飲料粉末
KR102868940B1 (ko) * 2018-06-27 2025-10-02 아를라 푸즈 에이엠비에이 알파-락트알부민-풍부 조성물을 제조하는 신규한 방법, 관련 제품 및 예를 들어 유아용 조제분유에서의 용도
WO2024032881A1 (en) 2022-08-10 2024-02-15 Arla Foods Amba Crystallisation of a protein capable of crystallizing under salting-in conditions using multiple protein feeds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3642582A (en) * 1969-07-14 1972-02-15 Standard Brands Inc Purification of alpha amylase
US4659667A (en) * 1985-02-26 1987-04-21 Miles Laboratories, Inc. Process to recover crystalline enzymes and crystalline enzymes produced thereby
DK122686D0 (da) † 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
EP0305216B1 (en) † 1987-08-28 1995-08-02 Novo Nordisk A/S Recombinant Humicola lipase and process for the production of recombinant humicola lipases

Also Published As

Publication number Publication date
ES2124400T3 (es) 1999-02-01
EP0691982A1 (en) 1996-01-17
FI954648A0 (fi) 1995-09-29
EP0691982B1 (en) 1998-09-16
JP3542601B2 (ja) 2004-07-14
AU6424294A (en) 1994-10-24
DE69413389T2 (de) 1999-04-29
WO1994022903A1 (en) 1994-10-13
DK39693D0 (da) 1993-04-02
DE69413389D1 (de) 1998-10-22
FI954648L (fi) 1995-09-29
JPH08508168A (ja) 1996-09-03
FI954648A7 (fi) 1995-09-29
CN1120340A (zh) 1996-04-10
DK0691982T3 (da) 1999-06-14
ATE171189T1 (de) 1998-10-15
EP0691982B2 (en) 2008-03-12
KR960701082A (ko) 1996-02-24
CN1039244C (zh) 1998-07-22
US5719048A (en) 1998-02-17

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Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
FC Decision: refusal