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BR9307342A - Low allergenicity process for the production of the same protein variant and composition - Google Patents

Low allergenicity process for the production of the same protein variant and composition

Info

Publication number
BR9307342A
BR9307342A BR9307342A BR9307342A BR9307342A BR 9307342 A BR9307342 A BR 9307342A BR 9307342 A BR9307342 A BR 9307342A BR 9307342 A BR9307342 A BR 9307342A BR 9307342 A BR9307342 A BR 9307342A
Authority
BR
Brazil
Prior art keywords
composition
production
same protein
protein variant
low allergenicity
Prior art date
Application number
BR9307342A
Other languages
Portuguese (pt)
Inventor
Uffe Loevborg
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of BR9307342A publication Critical patent/BR9307342A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2/00—Peptides of undefined number of amino acids; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6437—Coagulation factor VIIa (3.4.21.21)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38636—Preparations containing enzymes, e.g. protease or amylase containing enzymes other than protease, amylase, lipase, cellulase, oxidase or reductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21021—Coagulation factor VIIa (3.4.21.21)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Peptides Or Proteins (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
BR9307342A 1992-10-30 1993-10-28 Low allergenicity process for the production of the same protein variant and composition BR9307342A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK921328A DK132892D0 (en) 1992-10-30 1992-10-30 PROTEINS
PCT/DK1993/000344 WO1994010191A1 (en) 1992-10-30 1993-10-28 Low allergenic proteins

Publications (1)

Publication Number Publication Date
BR9307342A true BR9307342A (en) 1999-05-25

Family

ID=8103628

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9307342A BR9307342A (en) 1992-10-30 1993-10-28 Low allergenicity process for the production of the same protein variant and composition

Country Status (8)

Country Link
EP (1) EP0668868A1 (en)
JP (1) JPH08502498A (en)
KR (1) KR950704345A (en)
BR (1) BR9307342A (en)
CA (1) CA2147741A1 (en)
DK (1) DK132892D0 (en)
FI (1) FI952069L (en)
WO (1) WO1994010191A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3924095A (en) * 1994-11-24 1996-06-17 Novo Nordisk A/S A process for producing polypeptides with reduced allergenicity
JPH10510516A (en) 1994-12-07 1998-10-13 ノボ ノルディスク アクティーゼルスカブ Polypeptides with reduced allergenicity
US5629278A (en) * 1995-09-18 1997-05-13 The Proctor & Gamble Company Detergent compositions
US6946280B1 (en) * 1996-03-29 2005-09-20 Genencor International, Inc. Enzyme multimer and process of producing same
GB9613758D0 (en) † 1996-07-01 1996-09-04 Unilever Plc Detergent composition
BR9612799A (en) * 1996-08-09 2000-10-31 Procter & Gamble Detergent composition comprising pectoliase
JP2000507640A (en) * 1996-08-09 2000-06-20 ザ、プロクター、エンド、ギャンブル、カンパニー Detergent composition containing alkaline polygalacturonase
WO1998021302A1 (en) * 1996-11-14 1998-05-22 Polymer Technology Corporation Use of water soluble enzyme-polymer conjugates for cleaning contact lenses
US6936249B1 (en) 1998-04-15 2005-08-30 Genencor International, Inc. Proteins producing an altered immunogenic response and methods of making and using the same
US6642011B2 (en) 1998-04-15 2003-11-04 Genencor International, Inc. Human protease and use of such protease for pharmaceutical applications and for reducing the allergenicity of non-human proteins
US6835550B1 (en) 1998-04-15 2004-12-28 Genencor International, Inc. Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
EP1074563A1 (en) * 1999-08-02 2001-02-07 F. Hoffmann-La Roche Ag Chimeric polypeptides enhancing dimer formation through electrostatic interactions and disulfide bond, method for production and uses thereof
RU2311458C2 (en) 2001-03-23 2007-11-27 Джененкор Интернэшнл, Инк. Proteins causing alternated immunogenic response and methods for their preparing and using
US7332320B2 (en) 2001-12-31 2008-02-19 Genencor International, Inc. Protease producing an altered immunogenic response and methods of making and using the same
AU2003214023A1 (en) * 2002-03-12 2003-09-22 Novo Nordisk A/S Dimeric tf antagonist comprising two factor vii polypeptides
EP2500423B1 (en) 2003-02-26 2015-06-17 Danisco US Inc. Amylases producing an altered immunogenic response and methods of making and using the same
AU2003213273A1 (en) 2003-02-26 2004-09-28 Genencor International, Inc. Amylases producing an altered immunogenic response and methods of making and using the same
GB201106742D0 (en) 2011-04-20 2011-06-01 Spheritech Ltd Cross-linked poly-e-lysine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4844897A (en) * 1985-09-13 1989-07-04 Hiroshi Maeda Anti-tumor protease preparations

Also Published As

Publication number Publication date
KR950704345A (en) 1995-11-20
WO1994010191A1 (en) 1994-05-11
CA2147741A1 (en) 1994-05-11
FI952069A0 (en) 1995-04-28
DK132892D0 (en) 1992-10-30
FI952069A7 (en) 1995-04-28
EP0668868A1 (en) 1995-08-30
JPH08502498A (en) 1996-03-19
FI952069L (en) 1995-04-28

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Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
FC Decision: refusal