BR8901174A - Processo para a separacao de ester metilico de alfa-l-aspartil-l-fenilalanina - Google Patents
Processo para a separacao de ester metilico de alfa-l-aspartil-l-fenilalaninaInfo
- Publication number
- BR8901174A BR8901174A BR898901174A BR8901174A BR8901174A BR 8901174 A BR8901174 A BR 8901174A BR 898901174 A BR898901174 A BR 898901174A BR 8901174 A BR8901174 A BR 8901174A BR 8901174 A BR8901174 A BR 8901174A
- Authority
- BR
- Brazil
- Prior art keywords
- alpha
- aspartyl
- methyl ester
- phenylalanine methyl
- separation
- Prior art date
Links
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000000926 separation method Methods 0.000 title 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 2
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000012535 impurity Substances 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Seasonings (AREA)
- Extraction Or Liquid Replacement (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5821088 | 1988-03-14 | ||
| JP13506088 | 1988-06-01 | ||
| JP14367388 | 1988-06-13 | ||
| JP15686688 | 1988-06-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR8901174A true BR8901174A (pt) | 1989-10-31 |
Family
ID=27463624
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR898901174A BR8901174A (pt) | 1988-03-14 | 1989-03-13 | Processo para a separacao de ester metilico de alfa-l-aspartil-l-fenilalanina |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0333036B1 (pt) |
| JP (1) | JP2662287B2 (pt) |
| KR (1) | KR910006286B1 (pt) |
| CN (1) | CN1036201C (pt) |
| AT (1) | ATE156840T1 (pt) |
| AU (1) | AU605683B2 (pt) |
| BR (1) | BR8901174A (pt) |
| CA (1) | CA1339657C (pt) |
| DE (1) | DE68928249T2 (pt) |
| DK (1) | DK123089A (pt) |
| NO (1) | NO891069L (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1017289A1 (en) * | 1997-09-24 | 2000-07-12 | Holland Sweetener Company V.o.F. | Sweetening composition comprising aspartame and 2,4-dihydroxybenzoic acid |
| US7297813B2 (en) | 2004-08-05 | 2007-11-20 | Arkema Inc. | Removal of alkyl alkanesulfonate esters from alkanesulfonic acids and other organic media |
| JP6564539B1 (ja) * | 2018-09-14 | 2019-08-21 | 長瀬産業株式会社 | スルホン酸化合物によるペプチド精製方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5113737A (en) * | 1974-07-23 | 1976-02-03 | Ajinomoto Kk | Arufua ll asuparuchiru ll fueniruaraninteikyuarukiruesuteruno seizoho |
| IE810577L (en) * | 1983-05-31 | 1982-09-16 | Prendergast Angela | Apparatus for fermentation |
| US4439460A (en) * | 1982-06-01 | 1984-03-27 | G. D. Searle & Co. | Dipeptide sweetener sulfate and sulfonate salts |
| GB2140805B (en) * | 1983-05-31 | 1986-08-13 | Erba Farmitalia | Isolation of aspartame |
| GB8321802D0 (en) * | 1983-08-12 | 1983-09-14 | Erba Farmitalia | Aspartame synthesis |
-
1989
- 1989-02-20 JP JP1038188A patent/JP2662287B2/ja not_active Expired - Lifetime
- 1989-03-09 AT AT89104194T patent/ATE156840T1/de not_active IP Right Cessation
- 1989-03-09 DE DE68928249T patent/DE68928249T2/de not_active Expired - Fee Related
- 1989-03-09 EP EP89104194A patent/EP0333036B1/en not_active Expired - Lifetime
- 1989-03-10 CA CA000593429A patent/CA1339657C/en not_active Expired - Fee Related
- 1989-03-11 KR KR1019890002995A patent/KR910006286B1/ko not_active Expired
- 1989-03-13 NO NO89891069A patent/NO891069L/no unknown
- 1989-03-13 BR BR898901174A patent/BR8901174A/pt unknown
- 1989-03-13 CN CN89101475A patent/CN1036201C/zh not_active Expired - Fee Related
- 1989-03-14 DK DK123089A patent/DK123089A/da not_active Application Discontinuation
- 1989-03-14 AU AU31277/89A patent/AU605683B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2662287B2 (ja) | 1997-10-08 |
| KR910006286B1 (ko) | 1991-08-19 |
| DK123089A (da) | 1989-09-15 |
| EP0333036B1 (en) | 1997-08-13 |
| NO891069D0 (no) | 1989-03-13 |
| EP0333036A3 (en) | 1991-05-08 |
| AU605683B2 (en) | 1991-01-17 |
| DK123089D0 (da) | 1989-03-14 |
| DE68928249T2 (de) | 1998-02-26 |
| JPH0285295A (ja) | 1990-03-26 |
| CN1036580A (zh) | 1989-10-25 |
| DE68928249D1 (de) | 1997-09-18 |
| ATE156840T1 (de) | 1997-08-15 |
| KR890014575A (ko) | 1989-10-24 |
| CN1036201C (zh) | 1997-10-22 |
| CA1339657C (en) | 1998-02-03 |
| NO891069L (no) | 1989-09-15 |
| AU3127789A (en) | 1989-09-14 |
| EP0333036A2 (en) | 1989-09-20 |
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