BR0315569A - Apresentação farmacêutica de liberação prolongada contendo alfuzosina - Google Patents
Apresentação farmacêutica de liberação prolongada contendo alfuzosinaInfo
- Publication number
- BR0315569A BR0315569A BR0315569-2A BR0315569A BR0315569A BR 0315569 A BR0315569 A BR 0315569A BR 0315569 A BR0315569 A BR 0315569A BR 0315569 A BR0315569 A BR 0315569A
- Authority
- BR
- Brazil
- Prior art keywords
- alfuzosine
- release
- functional layer
- prolonged release
- single functional
- Prior art date
Links
- WNMJYKCGWZFFKR-UHFFFAOYSA-N alfuzosin Chemical compound N=1C(N)=C2C=C(OC)C(OC)=CC2=NC=1N(C)CCCNC(=O)C1CCCO1 WNMJYKCGWZFFKR-UHFFFAOYSA-N 0.000 title abstract 4
- 230000002035 prolonged effect Effects 0.000 title abstract 2
- 239000002346 layers by function Substances 0.000 abstract 4
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000012453 solvate Substances 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229960004607 alfuzosin Drugs 0.000 abstract 1
- 238000013265 extended release Methods 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 230000000979 retarding effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
"APRESENTAçãO FARMACêUTICA DE LIBERAçãO PROLONGADA CONTENDO ALFUZOSINA". A presente invenção refere-se a composições farmacêuticas de alfuzosina ou sal farmaceuticamente aceitável, solvato, enantiómeros ou misturas desses, que liberam o ingrediente ativo durante um período de tempo prolongado. A composição farmacêutica pode ser uma apresentação farmacêutica oral de liberação prolongada que inclui uma camada funcional única e, opcionalmente, uma ou mais camadas não funcionais adjacentes à camada única funcional. A camada única funcional inclui alfuzosina ou seus sais farmaceuticamente aceitáveis, solvatos, enantiómeros ou misturas desses e um ou mais ingredientes retardadores de liberação.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1056DE2002 | 2002-10-22 | ||
| PCT/IB2003/004677 WO2004037228A1 (en) | 2002-10-22 | 2003-10-22 | Sustained release compositions containing alfuzosin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0315569A true BR0315569A (pt) | 2005-08-30 |
Family
ID=34631110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0315569-2A BR0315569A (pt) | 2002-10-22 | 2003-10-22 | Apresentação farmacêutica de liberação prolongada contendo alfuzosina |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20060147530A1 (pt) |
| EP (1) | EP1556014A1 (pt) |
| CN (1) | CN1720026A (pt) |
| AU (1) | AU2003278407A1 (pt) |
| BR (1) | BR0315569A (pt) |
| EA (1) | EA200500672A1 (pt) |
| MX (1) | MXPA05004338A (pt) |
| WO (1) | WO2004037228A1 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060062846A1 (en) * | 2004-09-17 | 2006-03-23 | Cimex Pharma Ag | Alfuzosin tablets and synthesis |
| ITMI20050391A1 (it) * | 2005-03-11 | 2006-09-12 | Ph & T S P A | Formulazioni a rilascio controllato di alfuzosin |
| WO2007080509A2 (en) * | 2006-01-12 | 2007-07-19 | Wockhardt Ltd | Sustained release compositions of alfuzosin |
| US20070292505A1 (en) * | 2006-06-15 | 2007-12-20 | Abrika Pharmaceuticals, Inc. | Controlled release alfuzosin hydrochloride formulation |
| US20080095844A1 (en) * | 2006-10-23 | 2008-04-24 | Rajhans Sujay Kamalakar | Sustained release pharmaceutical compositions of alfuzosin and process for preparation thereof |
| US20080160081A1 (en) * | 2006-12-11 | 2008-07-03 | Mutual Pharmaceutical Company, Inc. | Alfuzosin formulations, methods of making, and methods of use |
| US20100092556A1 (en) * | 2006-12-11 | 2010-04-15 | Kristin Arnold | Alfuzosin formulations, methods of making, and methods of use |
| WO2008102235A1 (en) * | 2007-02-20 | 2008-08-28 | Aurobindo Pharma Limited | Controlled release formulations of alfuzosin |
| US20100183717A1 (en) * | 2009-01-16 | 2010-07-22 | Kristin Arnold | Controlled-release formulations |
| RU2442570C1 (ru) * | 2010-11-18 | 2012-02-20 | Ангук Фармасьютикал Ко., Лтд. | Таблетка с замедленным высвобождением, содержащая гидрохлорид альфузозина |
| CN105287422A (zh) * | 2015-12-07 | 2016-02-03 | 黑龙江省智诚医药科技有限公司 | 一种盐酸阿夫唑嗪缓释片及其制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4259314A (en) * | 1979-12-10 | 1981-03-31 | Hans Lowey | Method and composition for the preparation of controlled long-acting pharmaceuticals |
| US4680323A (en) * | 1983-12-01 | 1987-07-14 | Hans Lowey | Method and composition for the preparation of controlled long-acting pharmaceuticals for oral administration |
| US4704285A (en) * | 1985-11-18 | 1987-11-03 | The Dow Chemical Company | Sustained release compositions comprising hydroxypropyl cellulose ethers |
| GB9311191D0 (en) * | 1993-05-29 | 1993-07-14 | Danbiosyst Uk | Controlled release drug formulation |
| FR2717388B1 (fr) * | 1994-03-21 | 1996-11-22 | Synthelabo | Formes galéniques à libération prolongée du chlorhydrate d'alfuzosine. |
| US6096339A (en) * | 1997-04-04 | 2000-08-01 | Alza Corporation | Dosage form, process of making and using same |
| NZ334018A (en) * | 1996-08-29 | 1999-06-29 | Synthelabo | Multilayered controlled release tablet comprising a layer of alfuzosin hydrochloride and at least one layer of hydrophillic polymers |
| EP1064938A1 (en) * | 1999-06-28 | 2001-01-03 | Sanofi-Synthelabo | Pharmaceutical dosage forms for controlled release producing at least a timed pulse |
| FR2820319B3 (fr) * | 2001-02-08 | 2003-12-05 | Ellipse Pharmaceuticals | Procede de fabrication d'un comprime flottant incluant de l'alfuzosine et comprime obtenu |
-
2003
- 2003-10-22 MX MXPA05004338A patent/MXPA05004338A/es unknown
- 2003-10-22 CN CNA2003801050883A patent/CN1720026A/zh active Pending
- 2003-10-22 BR BR0315569-2A patent/BR0315569A/pt not_active IP Right Cessation
- 2003-10-22 EA EA200500672A patent/EA200500672A1/ru unknown
- 2003-10-22 EP EP03769713A patent/EP1556014A1/en not_active Withdrawn
- 2003-10-22 US US10/532,296 patent/US20060147530A1/en not_active Abandoned
- 2003-10-22 AU AU2003278407A patent/AU2003278407A1/en not_active Abandoned
- 2003-10-22 WO PCT/IB2003/004677 patent/WO2004037228A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003278407A1 (en) | 2004-05-13 |
| US20060147530A1 (en) | 2006-07-06 |
| WO2004037228A1 (en) | 2004-05-06 |
| WO2004037228A8 (en) | 2004-08-26 |
| EP1556014A1 (en) | 2005-07-27 |
| MXPA05004338A (es) | 2005-06-22 |
| EA200500672A1 (ru) | 2005-12-29 |
| CN1720026A (zh) | 2006-01-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A , 6A , E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2073 DE 28/09/2010. |