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BR0315112A - Sal de adição ácido, e, processo para a preparação de um composto - Google Patents

Sal de adição ácido, e, processo para a preparação de um composto

Info

Publication number
BR0315112A
BR0315112A BR0315112-3A BR0315112A BR0315112A BR 0315112 A BR0315112 A BR 0315112A BR 0315112 A BR0315112 A BR 0315112A BR 0315112 A BR0315112 A BR 0315112A
Authority
BR
Brazil
Prior art keywords
compound
acid addition
addition salt
preparation
aryl
Prior art date
Application number
BR0315112-3A
Other languages
English (en)
Inventor
David Cladingboel
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BR0315112A publication Critical patent/BR0315112A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

"SAL DE ADIçãO áCIDO, E, PROCESSO PARA A PREPARAçãO DE UM COMPOSTO". Um sal de adição ácido de um composto da fórmula I, onde R^ 2^ representa alquila C~ 1-6~ (opcionalmente substituído e/ou terminado por um ou mais substituintes escolhidos de -OH, halo, ciano, nitro e arila) ou arila, onde cada grupo arila e arilóxi, a não ser que seja especificado de outra forma, é opcionalmente substituído.
BR0315112-3A 2002-10-14 2003-10-13 Sal de adição ácido, e, processo para a preparação de um composto BR0315112A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0223712.1A GB0223712D0 (en) 2002-10-14 2002-10-14 Chemical intermediate
PCT/SE2003/001594 WO2004035592A1 (en) 2002-10-14 2003-10-13 Chemical intermediate

Publications (1)

Publication Number Publication Date
BR0315112A true BR0315112A (pt) 2005-08-16

Family

ID=9945773

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0315112-3A BR0315112A (pt) 2002-10-14 2003-10-13 Sal de adição ácido, e, processo para a preparação de um composto

Country Status (25)

Country Link
US (2) US7314931B2 (pt)
EP (1) EP1554285B1 (pt)
JP (1) JP4476810B2 (pt)
KR (1) KR20050056239A (pt)
CN (1) CN1319976C (pt)
AT (1) ATE455118T1 (pt)
AU (1) AU2003269768B2 (pt)
BR (1) BR0315112A (pt)
CA (1) CA2501413A1 (pt)
DE (1) DE60330982D1 (pt)
DK (1) DK1554285T3 (pt)
ES (1) ES2337998T3 (pt)
GB (1) GB0223712D0 (pt)
IL (1) IL167778A (pt)
IS (1) IS7841A (pt)
MX (1) MXPA05003812A (pt)
NO (1) NO20051627L (pt)
NZ (1) NZ539371A (pt)
PL (1) PL375100A1 (pt)
PT (1) PT1554285E (pt)
RU (1) RU2326122C2 (pt)
SI (1) SI1554285T1 (pt)
UA (1) UA79986C2 (pt)
WO (1) WO2004035592A1 (pt)
ZA (1) ZA200502579B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR030756A1 (es) * 2000-10-02 2003-09-03 Astrazeneca Ab Compuesto de oxabispidina util en el tratamiento de arritmias cardiacas
GB0223712D0 (en) * 2002-10-14 2002-11-20 Astrazeneca Ab Chemical intermediate
SE0401539D0 (sv) 2004-06-15 2004-06-15 Astrazeneca Ab New compounds
JP2008543750A (ja) * 2005-06-13 2008-12-04 アストラゼネカ アクチボラグ 心不整脈の処置用の新規オキサビスピジン化合物
WO2006137770A1 (en) * 2005-06-20 2006-12-28 Astrazeneca Ab Process for the preparation of n,n´- disubstituted oxabispidines
AR054391A1 (es) * 2005-06-20 2007-06-20 Astrazeneca Ab Procedimiento para la preparacion de 3,7- dihidroxi-1,5-diazaciclooctanos
AR054284A1 (es) * 2005-06-20 2007-06-13 Astrazeneca Ab Procedimiento para la preparacion de sales de acido sulfonico de oxabispidinas
AR053901A1 (es) * 2005-06-20 2007-05-23 Astrazeneca Ab Formas fisicas de oxabispidinas n,n'- disustituidas
TW200734342A (en) * 2005-12-15 2007-09-16 Astrazeneca Ab New compounds for the treatment of cardiac arrhythmias
BR112015021985B1 (pt) 2013-03-15 2022-12-13 Global Blood Therapeutics, Inc Compostos ou sais farmaceuticamente aceitáveis dos mesmos, respectivos usos e composição
EA202092627A1 (ru) 2013-11-18 2021-09-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
US12084472B2 (en) 2015-12-18 2024-09-10 Ardelyx, Inc. Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists
TWI773657B (zh) 2015-12-18 2022-08-11 美商亞德利克斯公司 作爲非全身ｔｇｒ５促效劑之經取代之4-苯基吡啶化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9903759D0 (sv) * 1999-10-18 1999-10-18 Astra Ab Pharmaceutically active compounds
AR030756A1 (es) * 2000-10-02 2003-09-03 Astrazeneca Ab Compuesto de oxabispidina util en el tratamiento de arritmias cardiacas
SE0101324D0 (sv) 2001-04-12 2001-04-12 Astrazeneca Ab New process
GB0223712D0 (en) * 2002-10-14 2002-11-20 Astrazeneca Ab Chemical intermediate

Also Published As

Publication number Publication date
IL167778A (en) 2010-04-29
EP1554285B1 (en) 2010-01-13
HK1082498A1 (en) 2006-06-09
NO20051627L (no) 2005-05-06
AU2003269768A1 (en) 2004-05-04
ES2337998T3 (es) 2010-05-03
RU2005109158A (ru) 2006-01-20
HK1078861A1 (en) 2006-03-24
DK1554285T3 (da) 2010-04-19
US7314931B2 (en) 2008-01-01
IS7841A (is) 2005-05-12
RU2326122C2 (ru) 2008-06-10
PT1554285E (pt) 2010-03-08
MXPA05003812A (es) 2005-06-08
UA79986C2 (en) 2007-08-10
JP4476810B2 (ja) 2010-06-09
PL375100A1 (en) 2005-11-14
US20060199814A1 (en) 2006-09-07
EP1554285A1 (en) 2005-07-20
DE60330982D1 (de) 2010-03-04
WO2004035592A1 (en) 2004-04-29
ZA200502579B (en) 2006-02-22
CN1319976C (zh) 2007-06-06
AU2003269768B2 (en) 2007-08-23
US20090062532A1 (en) 2009-03-05
CA2501413A1 (en) 2004-04-29
SI1554285T1 (sl) 2010-04-30
NZ539371A (en) 2006-10-27
JP2006505565A (ja) 2006-02-16
KR20050056239A (ko) 2005-06-14
ATE455118T1 (de) 2010-01-15
GB0223712D0 (en) 2002-11-20
CN1705671A (zh) 2005-12-07

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012.