BR0312814A - Levamisol / avermectinas ou similares em solvente de pirrolidona - Google Patents
Levamisol / avermectinas ou similares em solvente de pirrolidonaInfo
- Publication number
- BR0312814A BR0312814A BR0312814-8A BR0312814A BR0312814A BR 0312814 A BR0312814 A BR 0312814A BR 0312814 A BR0312814 A BR 0312814A BR 0312814 A BR0312814 A BR 0312814A
- Authority
- BR
- Brazil
- Prior art keywords
- levamisol
- avermectins
- pyrrolidone solvent
- solvent
- pyrrolidone
- Prior art date
Links
- 239000002904 solvent Substances 0.000 title abstract 3
- 239000005660 Abamectin Substances 0.000 title abstract 2
- HLFSDGLLUJUHTE-SNVBAGLBSA-N Levamisole Chemical compound C1([C@H]2CN3CCSC3=N2)=CC=CC=C1 HLFSDGLLUJUHTE-SNVBAGLBSA-N 0.000 title abstract 2
- 229960001614 levamisole Drugs 0.000 title abstract 2
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 229940058299 avermectines Drugs 0.000 abstract 1
- FXWHFKOXMBTCMP-WMEDONTMSA-N milbemycin Natural products COC1C2OCC3=C/C=C/C(C)CC(=CCC4CC(CC5(O4)OC(C)C(C)C(OC(=O)C(C)CC(C)C)C5O)OC(=O)C(C=C1C)C23O)C FXWHFKOXMBTCMP-WMEDONTMSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
"LEVAMISOL/AVERMECTINAS OU SIMILARES EM SOLVENTE DE PIRROLIDONA". A presente invenção refere-se a uma formulação estável, que é adequada para administração a animais. A formulação inclui pelo menos uma substância ativa, selecionada do grupo compreendendo avermectinas e milbemicina e levamisol. Ambas as ditas substâncias ativas são dissolvidas em um solvente de pirrolidona.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ520295A NZ520295A (en) | 2002-07-19 | 2002-07-19 | Anthelmintic formulations comprising levamisole and either an avermectin or milbemycin |
| PCT/NZ2003/000157 WO2004009080A1 (en) | 2002-07-19 | 2003-07-21 | Levamisole, Avermectins or similar in pyrrolidone solvent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR0312814A true BR0312814A (pt) | 2005-04-19 |
| BRPI0312814B1 BRPI0312814B1 (pt) | 2017-06-06 |
Family
ID=30768277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0312814A BRPI0312814B1 (pt) | 2002-07-19 | 2003-07-21 | levamisol / avermectinas ou similares em solvente de pirrolidona |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20060128641A1 (pt) |
| EP (1) | EP1551390B1 (pt) |
| AU (2) | AU2003281472B2 (pt) |
| BR (1) | BRPI0312814B1 (pt) |
| DK (1) | DK1551390T3 (pt) |
| NZ (1) | NZ520295A (pt) |
| SI (1) | SI1551390T1 (pt) |
| WO (1) | WO2004009080A1 (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA82359C2 (uk) * | 2003-04-03 | 2008-04-10 | Schering Plough Ltd | Композиція (варіанти) і спосіб лікування мікробних і паразитних інфекцій у великої рогатої худоби і інших тварин |
| NZ553656A (en) * | 2004-09-09 | 2010-01-29 | Warburton Technology Ltd | Injectable composition for animals comprising trace elements and other components |
| AU2006242966A1 (en) | 2005-04-29 | 2006-11-09 | Mercatus Technologies Inc. | Systems and methods for managing a hierarchical structure |
| AR056808A1 (es) * | 2005-11-18 | 2007-10-24 | Cheminova As | Formulacion de aceite en agua de avermectinas |
| BRPI0506279B1 (pt) | 2005-12-16 | 2018-01-09 | Npa - Núcleo De Pesquisas Aplicadas Ltda | Composição sinergística de antihelmínticos e endectocidas |
| NZ552040A (en) * | 2006-12-13 | 2009-04-30 | Bomac Research Ltd | Veterinary formulation comprising an anthelmintic compound and glyceryl acetate |
| AU2013201461B2 (en) * | 2007-11-26 | 2015-10-29 | Boehringer Ingelheim Animal Health USA Inc. | Solvent systems for pour-on formulations for combating parasites |
| BRPI0819849B8 (pt) * | 2007-11-26 | 2021-05-25 | Merial Ltd | sistemas de solvente para formulações pour on para combater parasitas |
| UA108641C2 (uk) | 2010-04-02 | 2015-05-25 | Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування | |
| AU2016201743B2 (en) * | 2010-05-12 | 2017-10-19 | Boehringer Ingelheim Animal Health USA Inc. | Injectable parasiticidal formulations of levamisole and macrocyclic lactones |
| HUE028600T2 (en) * | 2010-05-12 | 2016-12-28 | Merial Inc | Injectable parasiticidal formulations of levamisole and macrocyclic lactones |
| AR081970A1 (es) | 2010-06-24 | 2012-10-31 | Intervet Int Bv | Formulacion inyectable de una lactona macrociclica y levamisol, formulacion y uso veterinario |
| WO2012078605A1 (en) | 2010-12-07 | 2012-06-14 | Merial Limited | Topical combination formulations of macrocyclic lactones with synthetic pyrethroids |
| BR112013032567B1 (pt) * | 2011-06-23 | 2020-04-28 | Bayer New Zealand Ltd | composição aquosa antiparasitária veterinária solubilizada |
| NZ594610A (en) | 2011-08-16 | 2013-03-28 | Virbac New Zealand Ltd | Injectable Anthelmintic Formulations cotaining levamisole and one or more macrocyclic lactones for controlling internal parasites in ruminants |
| EP3749096A1 (en) | 2018-02-08 | 2020-12-16 | Boehringer Ingelheim Animal Health USA Inc. | Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof |
| AU2020208145B2 (en) * | 2019-01-16 | 2023-02-02 | Boehringer Ingelheim Vetmedica Gmbh | Topical compositions comprising a neonicotinoid and a macrocyclic lactone, methods and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6426333B1 (en) * | 1996-09-19 | 2002-07-30 | Merial | Spot-on formulations for combating parasites |
| US5773422A (en) * | 1996-01-29 | 1998-06-30 | Komer; Gene | Avermectin formulation |
| EP0959891A1 (en) * | 1996-07-30 | 1999-12-01 | Ashmont Holdings Limited | Anthelmintic formulations |
| ZA981925B (en) * | 1997-03-21 | 1998-10-23 | Biogenesis S A | A long acting injectable parasiticidal composition and the process for its preparation |
| AR035550A1 (es) * | 1999-06-04 | 2004-06-16 | Nufarm Ltd | Composiciones estables biocidas |
| US6780885B1 (en) * | 2000-01-14 | 2004-08-24 | Idexx Laboratories, Inc. | Formulations and methods for administration of pharmacologically or biologically active compounds |
| US6340672B1 (en) * | 2000-02-16 | 2002-01-22 | Phoenix Scientific, Inc. | Parasiticidal formulation and a method of making this formulation |
-
2002
- 2002-07-19 NZ NZ520295A patent/NZ520295A/en not_active IP Right Cessation
-
2003
- 2003-07-21 BR BRPI0312814A patent/BRPI0312814B1/pt active IP Right Grant
- 2003-07-21 WO PCT/NZ2003/000157 patent/WO2004009080A1/en not_active Ceased
- 2003-07-21 EP EP03741701.1A patent/EP1551390B1/en not_active Expired - Lifetime
- 2003-07-21 DK DK03741701.1T patent/DK1551390T3/da active
- 2003-07-21 SI SI200332354T patent/SI1551390T1/sl unknown
- 2003-07-21 US US10/521,604 patent/US20060128641A1/en not_active Abandoned
- 2003-07-21 AU AU2003281472A patent/AU2003281472B2/en not_active Expired
-
2005
- 2005-01-11 AU AU2005200099A patent/AU2005200099A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005200099A1 (en) | 2005-03-17 |
| NZ520295A (en) | 2005-04-29 |
| DK1551390T3 (da) | 2014-04-28 |
| US20060128641A1 (en) | 2006-06-15 |
| AU2003281472A1 (en) | 2004-02-09 |
| SI1551390T1 (sl) | 2014-07-31 |
| AU2003281472B2 (en) | 2008-07-24 |
| EP1551390A1 (en) | 2005-07-13 |
| EP1551390B1 (en) | 2014-04-02 |
| EP1551390A4 (en) | 2008-11-05 |
| WO2004009080A1 (en) | 2004-01-29 |
| BRPI0312814B1 (pt) | 2017-06-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B25A | Requested transfer of rights approved |
Owner name: MERIAL LIMITED (GB) Free format text: TRANSFERIDO DE: ASHMONT HOLDINGS LIMITED |
|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] |
Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI. |
|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM OS ARTIGOS 8O, 11 E 13 DA LPI. |
|
| B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] | ||
| B25G | Requested change of headquarter approved | ||
| B25A | Requested transfer of rights approved | ||
| B25A | Requested transfer of rights approved |