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BR0309138A - Processo para a preparação de uma composição farmacêutica finamente auto-emulsionável - Google Patents

Processo para a preparação de uma composição farmacêutica finamente auto-emulsionável

Info

Publication number
BR0309138A
BR0309138A BR0309138-4A BR0309138A BR0309138A BR 0309138 A BR0309138 A BR 0309138A BR 0309138 A BR0309138 A BR 0309138A BR 0309138 A BR0309138 A BR 0309138A
Authority
BR
Brazil
Prior art keywords
pharmaceutical composition
pharmaceutically acceptable
preparation
composition
finely self
Prior art date
Application number
BR0309138-4A
Other languages
English (en)
Inventor
Ping Gao
Xioarong He
Keith B Bolyard
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of BR0309138A publication Critical patent/BR0309138A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"PROCESSO PARA A PREPARAçãO DE UMA COMPOSIçãO FARMACêUTICA FINAMENTE AUTO-EMULSIONáVEL". A presente invenção refere-se a uma composição farmacêutica que pode ser administrada por via oral compreendendo uma droga de baixa solubilidade em água e um líquido solvente que compreende pelo menos um solvente farmaceuticamente aceitável, pelo menos um ácido graxo farmaceuticamente aceitável e pelo menos uma amina orgânica farmaceuticamente aceitável, em que (a) uma porção considerável, por exemplo, pelo menos 15% em peso, da droga está em uma forma dissolvida ou solubilizada no líquido solvente e (b) o ácido graxo e a amina orgânica estão presentes em quantidades totais e relativas de tal modo que a composição é finamente auto-emulsionável no fluido gástrico simulado. é também proporcionado um processo para a preparação dessa composição.
BR0309138-4A 2002-04-09 2003-04-07 Processo para a preparação de uma composição farmacêutica finamente auto-emulsionável BR0309138A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37120002P 2002-04-09 2002-04-09
PCT/US2003/010526 WO2003086392A2 (en) 2002-04-09 2003-04-07 Process for preparing a finely self-emulsifiable pharmaceutical composition

Publications (1)

Publication Number Publication Date
BR0309138A true BR0309138A (pt) 2005-02-01

Family

ID=29250656

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0309138-4A BR0309138A (pt) 2002-04-09 2003-04-07 Processo para a preparação de uma composição farmacêutica finamente auto-emulsionável

Country Status (18)

Country Link
US (1) US20030235596A1 (pt)
EP (1) EP1492527B1 (pt)
JP (1) JP2005529104A (pt)
KR (1) KR100779285B1 (pt)
CN (1) CN1305470C (pt)
AT (1) ATE410162T1 (pt)
AU (1) AU2003223485B2 (pt)
BR (1) BR0309138A (pt)
CA (1) CA2481677A1 (pt)
DE (1) DE60323953D1 (pt)
ES (1) ES2310653T3 (pt)
IL (1) IL164163A0 (pt)
MX (1) MXPA04009880A (pt)
PL (1) PL372807A1 (pt)
RS (1) RS87004A (pt)
RU (1) RU2299061C2 (pt)
WO (1) WO2003086392A2 (pt)
ZA (1) ZA200407711B (pt)

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WO2007050724A2 (en) 2005-10-26 2007-05-03 Banner Pharmacaps, Inc. Lipophilic vehicle-based dual controlled release matrix system as capsule fill
EP3056220A1 (en) * 2007-04-11 2016-08-17 John A. Mccarty Hormone tablet and metods of preparation
JP5951489B2 (ja) 2009-10-16 2016-07-13 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニーＧｌａｘｏＳｍｉｔｈＫｌｉｎｅ ＬＬＣ 組成物
US20120322776A1 (en) * 2009-12-22 2012-12-20 Leo Pharma A/S Cutaneous composition comprising vitamin d analogue and a mixture of solvent and surfactants
AT511045A1 (de) 2011-01-28 2012-08-15 Blum Gmbh Julius Möbelteil mit einer drehmomentübertragenden welle
US9119826B2 (en) 2011-02-16 2015-09-01 Pivotal Therapeutics, Inc. Omega 3 fatty acid for use as a prescription medical food and omega 3 fatty acid diagniostic assay for the dietary management of cardiovascular patients with cardiovascular disease (CVD) who are deficient in blood EPA and DHA levels
US8952000B2 (en) 2011-02-16 2015-02-10 Pivotal Therapeutics Inc. Cholesterol absorption inhibitor and omega 3 fatty acids for the reduction of cholesterol and for the prevention or reduction of cardiovascular, cardiac and vascular events
US8951514B2 (en) 2011-02-16 2015-02-10 Pivotal Therapeutics Inc. Statin and omega 3 fatty acids for reduction of apolipoprotein-B levels
CA2856520C (en) 2011-11-23 2021-04-06 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
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US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
CN103965113A (zh) * 2014-05-06 2014-08-06 四川大学 1-羟乙基-2-取代苯氧甲基苯并咪唑类化合物及其制备方法
MX2016014281A (es) 2014-05-22 2017-02-22 Therapeuticsmd Inc Formulaciones y terapias de reemplazo de combinación de hormonas naturales.
US11400048B2 (en) 2014-06-25 2022-08-02 Synergia Bio Sciences Private Limited Pharmaceutical oil-in-water nano-emulsion
EP3160444B1 (en) 2014-06-25 2021-11-24 Synergia Bio Sciences Private Limited A pharmaceutical oil-in-water nano-emulsion
BR112016029338A2 (pt) 2014-07-29 2017-08-22 Therapeuticsmd Inc creme transdérmico
US9572819B2 (en) 2015-05-28 2017-02-21 Dr. Reddy's Laboratories, Ltd. Oral composition of celecoxib for treatment of pain
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
CN105343002B (zh) * 2015-11-27 2019-07-26 济南康和医药科技有限公司 一种依托考昔口服微乳制剂及其制备方法
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
MX2018011705A (es) 2016-04-01 2019-06-10 Therapeuticsmd Inc Composicion farmaceutica de hormona esteroide.
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations
CN111729125B (zh) * 2020-07-31 2022-10-04 陕西佰傲再生医学有限公司 骨止血材料
CN112645201A (zh) 2020-12-10 2021-04-13 通力电梯有限公司 用于设置自动扶梯的情景检测模块的状态的方法和装置
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Also Published As

Publication number Publication date
CN1305470C (zh) 2007-03-21
HK1076382A1 (en) 2006-01-20
WO2003086392A2 (en) 2003-10-23
RU2299061C2 (ru) 2007-05-20
ZA200407711B (en) 2006-06-28
US20030235596A1 (en) 2003-12-25
ATE410162T1 (de) 2008-10-15
ES2310653T3 (es) 2009-01-16
KR100779285B1 (ko) 2007-11-28
MXPA04009880A (es) 2004-12-07
EP1492527A2 (en) 2005-01-05
IL164163A0 (en) 2005-12-18
WO2003086392A3 (en) 2004-03-25
CA2481677A1 (en) 2003-10-23
KR20070014237A (ko) 2007-02-01
JP2005529104A (ja) 2005-09-29
EP1492527B1 (en) 2008-10-08
RU2004130291A (ru) 2005-05-27
AU2003223485B2 (en) 2007-05-31
RS87004A (sr) 2006-12-15
PL372807A1 (en) 2005-08-08
CN1658870A (zh) 2005-08-24
AU2003223485A1 (en) 2003-10-27
DE60323953D1 (de) 2008-11-20

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA: INT. CL. A61K 31/42, 9/107, 9/48, 31/02; A61P 29/00

Ipc: A61K 31/42 (2011.01), A61K 9/107 (2011.01), A61K 9

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A E 8A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE AS 7A, 8A E 9A ANUIDADES.