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BR0306988A - Piridazinonas substituìdas como inibidores de p38 - Google Patents

Piridazinonas substituìdas como inibidores de p38

Info

Publication number
BR0306988A
BR0306988A BR0306988-5A BR0306988A BR0306988A BR 0306988 A BR0306988 A BR 0306988A BR 0306988 A BR0306988 A BR 0306988A BR 0306988 A BR0306988 A BR 0306988A
Authority
BR
Brazil
Prior art keywords
inhibitors
pyridazinones
compounds
substituted
methods
Prior art date
Application number
BR0306988-5A
Other languages
English (en)
Inventor
Michael Hepperle
Kevin D Jerome
John Walker
Shaun Selness
Rajesh Devraj
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of BR0306988A publication Critical patent/BR0306988A/pt

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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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Abstract

"PIRIDAZINONAS SUBSTITUìDAS COMO INIBIDORES DE P38". São descritas piridazinonas substituídas que são úteis para o tratamento de doenças e condições provocadas ou exacerbadas por actividade não-regulada de p38 MAP cinase e/ou de TNF. São também descritas composições farmacêuticas que contêm os compostos de piridazinona, métodos de preparação dos compostos e métodos de tratamento usando-se os compostos.
BR0306988-5A 2002-01-18 2003-01-21 Piridazinonas substituìdas como inibidores de p38 BR0306988A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35074102P 2002-01-18 2002-01-18
US35504402P 2002-02-07 2002-02-07
PCT/US2003/001780 WO2003059891A1 (en) 2002-01-18 2003-01-21 Substituted pyridazinones as inhibitors of p38

Publications (1)

Publication Number Publication Date
BR0306988A true BR0306988A (pt) 2004-11-23

Family

ID=26996760

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0306988-5A BR0306988A (pt) 2002-01-18 2003-01-21 Piridazinonas substituìdas como inibidores de p38

Country Status (8)

Country Link
US (2) US20040142932A1 (pt)
EP (1) EP1470112A1 (pt)
JP (1) JP2005519895A (pt)
AU (1) AU2003209321A1 (pt)
BR (1) BR0306988A (pt)
CA (1) CA2474239A1 (pt)
MX (1) MXPA04006781A (pt)
WO (1) WO2003059891A1 (pt)

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