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BR0210241A - Piranoindazóis e seu uso no tratamento de glaucoma - Google Patents

Piranoindazóis e seu uso no tratamento de glaucoma

Info

Publication number
BR0210241A
BR0210241A BR0210241-2A BR0210241A BR0210241A BR 0210241 A BR0210241 A BR 0210241A BR 0210241 A BR0210241 A BR 0210241A BR 0210241 A BR0210241 A BR 0210241A
Authority
BR
Brazil
Prior art keywords
glaucoma
treatment
pyanoindazoles
disclosed
pyanoindoles
Prior art date
Application number
BR0210241-2A
Other languages
English (en)
Inventor
Hwang-Hsing Chen
Jesse A May
Bryon S Severns
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of BR0210241A publication Critical patent/BR0210241A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

"PIRANOINDAZóIS E SEU USO NO TRATAMENTO DE GLAUCOMA". Divulgam-se piranoindazóis. Divulgam-se também método para a diminuição e controle de pressão intra-ocular normal ou elevada assim como um método para o tratamento de glaucoma usando composições contendo um ou mais dos compostos da invenção presente.
BR0210241-2A 2001-06-01 2002-05-30 Piranoindazóis e seu uso no tratamento de glaucoma BR0210241A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29542901P 2001-06-01 2001-06-01
PCT/US2002/016861 WO2002098350A2 (en) 2001-06-01 2002-05-30 Pyranoindazoles and their use for the treatment of glaucoma

Publications (1)

Publication Number Publication Date
BR0210241A true BR0210241A (pt) 2004-08-10

Family

ID=23137684

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0210241-2A BR0210241A (pt) 2001-06-01 2002-05-30 Piranoindazóis e seu uso no tratamento de glaucoma

Country Status (19)

Country Link
US (2) US6696476B2 (pt)
EP (1) EP1392292B1 (pt)
JP (1) JP2004535418A (pt)
KR (1) KR100626255B1 (pt)
CN (1) CN100384417C (pt)
AR (1) AR036044A1 (pt)
AT (1) ATE318821T1 (pt)
AU (1) AU2002305732B2 (pt)
BR (1) BR0210241A (pt)
CA (1) CA2447480A1 (pt)
DE (1) DE60209486T2 (pt)
DK (1) DK1392292T3 (pt)
ES (1) ES2258631T3 (pt)
MX (1) MXPA03010807A (pt)
PL (1) PL366636A1 (pt)
PT (1) PT1392292E (pt)
RU (1) RU2273641C2 (pt)
WO (1) WO2002098350A2 (pt)
ZA (1) ZA200309034B (pt)

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EP1545501A2 (en) * 2002-08-30 2005-06-29 Alcon, Inc. Substituted 5-chroman-5-yl-ethylamine compounds and their use for the treatment of glaucoma
MXPA05006277A (es) 2002-12-13 2005-09-08 Alcon Inc Analogos de benzopirano novedosos y su uso para el tratamiento de glaucoma.
AU2004271978B2 (en) * 2003-09-04 2009-02-05 Merck & Co., Inc. Ophthalmic compositions for treating ocular hypertension
US7476687B2 (en) * 2003-11-26 2009-01-13 Alcon, Inc. Substituted furo[2,3-g]indazoles for the treatment of glaucoma
TW200520760A (en) 2003-12-15 2005-07-01 Alcon Inc Substituted [1,4] oxazino [2,3-g] indazoles for the treatment of glaucoma
US7338972B1 (en) 2003-12-15 2008-03-04 Alcon, Inc. Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma
US7129257B1 (en) * 2003-12-15 2006-10-31 Alcon, Inc. Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma
EP2400300A1 (en) 2004-08-25 2011-12-28 Takeda Pharmaceutical Company Limited Method of screening preventives/remedies for stress urinary incontinence
US20060073172A1 (en) * 2004-10-01 2006-04-06 Schneider L W Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure
WO2006062839A1 (en) 2004-12-08 2006-06-15 Alcon, Inc. Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma
TW200744567A (en) * 2005-09-23 2007-12-16 Alcon Inc Phenylethylamine analogs and their use for treating glaucoma
EP2727585A1 (en) 2006-05-16 2014-05-07 Takeda Pharmaceutical Company Limited In-vivo screening method
US20070293475A1 (en) * 2006-06-20 2007-12-20 Alcon Manufacturing Ltd. Aryl and heteroaryl tetrahydrobenzazepine derivatives and their use for treating glaucoma
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WO2008016993A1 (en) * 2006-08-01 2008-02-07 Alcon Research, Ltd. Intermediates and methods for serotonergic agonist synthesis
US20080033183A1 (en) * 2006-08-01 2008-02-07 Alcon Manufacturing, Ltd. Process for preparing pyranoindazole serotonergic receptor agonists
US20080058533A1 (en) * 2006-08-31 2008-03-06 Alcon, Inc. Pyranoindazole cyclic carbonates and methods of use
WO2009063992A1 (ja) 2007-11-15 2009-05-22 Takeda Pharmaceutical Company Limited 縮合ピリジン誘導体およびその用途
WO2011071136A1 (ja) 2009-12-11 2011-06-16 アステラス製薬株式会社 線維筋痛症治療剤
US20180030251A1 (en) * 2015-03-05 2018-02-01 Bridgestone Corporation Rubber composition, method for producing diene-based polymer, and tire
TW201815766A (zh) * 2016-09-22 2018-05-01 美商普雷辛肯公司 用於ｉｄｏ及ｔｄｏ調節之化合物及方法以及其適應症
US20210052600A1 (en) 2017-12-27 2021-02-25 Takeda Pharmaceutical Company Limited Therapeutic agents for stress urinary incontinence and incotinence of feces
CN112119072A (zh) 2018-03-20 2020-12-22 普莱希科公司 用于ido和tdo调节的化合物和方法，以及其适应症

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Also Published As

Publication number Publication date
US20040106609A1 (en) 2004-06-03
DE60209486D1 (de) 2006-04-27
PT1392292E (pt) 2006-05-31
AU2002305732B2 (en) 2007-02-01
MXPA03010807A (es) 2004-11-22
WO2002098350A3 (en) 2003-02-27
EP1392292A4 (en) 2004-08-11
ES2258631T3 (es) 2006-09-01
HK1061212A1 (en) 2004-09-10
US6881749B2 (en) 2005-04-19
EP1392292A2 (en) 2004-03-03
KR20040010669A (ko) 2004-01-31
WO2002098350A2 (en) 2002-12-12
RU2003137825A (ru) 2005-04-20
US20030171418A1 (en) 2003-09-11
DE60209486T2 (de) 2006-08-03
AR036044A1 (es) 2004-08-04
KR100626255B1 (ko) 2006-09-21
CN100384417C (zh) 2008-04-30
ATE318821T1 (de) 2006-03-15
PL366636A1 (en) 2005-02-07
CN1592619A (zh) 2005-03-09
RU2273641C2 (ru) 2006-04-10
CA2447480A1 (en) 2002-12-12
EP1392292B1 (en) 2006-03-01
ZA200309034B (en) 2004-07-16
JP2004535418A (ja) 2004-11-25
DK1392292T3 (da) 2006-05-29
US6696476B2 (en) 2004-02-24

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A E 9A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2108 DE 31/05/2011.