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BR0113861A - Derivados de ácidos 3-(heteroaril acetamido)-2-oxo-azetidina-1-sulfÈnicos como agentes antibacterianos - Google Patents

Derivados de ácidos 3-(heteroaril acetamido)-2-oxo-azetidina-1-sulfÈnicos como agentes antibacterianos

Info

Publication number
BR0113861A
BR0113861A BR0113861-8A BR0113861A BR0113861A BR 0113861 A BR0113861 A BR 0113861A BR 0113861 A BR0113861 A BR 0113861A BR 0113861 A BR0113861 A BR 0113861A
Authority
BR
Brazil
Prior art keywords
azetidine
oxo
antibacterial agents
sulfonic acid
acid derivatives
Prior art date
Application number
BR0113861-8A
Other languages
English (en)
Inventor
Ronald George Micetich
Samarendra Nath Maiti
Charles Fiakpui
George Thomas
Andhe V Narender Reddy
Sameeh M Salama
Rajeshwar Singh
Original Assignee
Pantherix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pantherix Ltd filed Critical Pantherix Ltd
Publication of BR0113861A publication Critical patent/BR0113861A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"DERIVADOS DE áCIDOS 3-(HETEROARIL ACETAMIDO)-2-OXO-AZETIDINA-1-SULFÈNICOS COMO AGENTES ANTIBACTERIANOS". A presente invenção está relacionada a novos isómeros Syn de racemados e isómeros ópticos de ácidos 3-(heteroaril acetamido)-2-oxo-azetidina-1-sulfónicos da fórmula (I) e o seu uso no tratamento das infeções causadas por bactérias patogênicas gram-negativas.
BR0113861-8A 2000-09-14 2001-09-14 Derivados de ácidos 3-(heteroaril acetamido)-2-oxo-azetidina-1-sulfÈnicos como agentes antibacterianos BR0113861A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23261700P 2000-09-14 2000-09-14
PCT/IB2001/002115 WO2002022613A1 (en) 2000-09-14 2001-09-14 3-(heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents

Publications (1)

Publication Number Publication Date
BR0113861A true BR0113861A (pt) 2004-01-27

Family

ID=22873854

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0113861-8A BR0113861A (pt) 2000-09-14 2001-09-14 Derivados de ácidos 3-(heteroaril acetamido)-2-oxo-azetidina-1-sulfÈnicos como agentes antibacterianos

Country Status (22)

Country Link
US (1) US6916803B2 (pt)
EP (1) EP1322648B1 (pt)
JP (1) JP2004509122A (pt)
KR (1) KR100854810B1 (pt)
CN (1) CN1189469C (pt)
AT (1) ATE298750T1 (pt)
AU (2) AU2002212614B2 (pt)
BR (1) BR0113861A (pt)
CA (1) CA2422375C (pt)
CZ (1) CZ304586B6 (pt)
DE (1) DE60111757T2 (pt)
DK (1) DK1322648T3 (pt)
ES (1) ES2244666T3 (pt)
HU (1) HUP0301025A3 (pt)
IL (2) IL154593A0 (pt)
NO (1) NO324946B1 (pt)
NZ (1) NZ524292A (pt)
PL (1) PL218196B1 (pt)
PT (1) PT1322648E (pt)
SK (1) SK2462003A3 (pt)
WO (1) WO2002022613A1 (pt)
ZA (1) ZA200302085B (pt)

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AU2012233003B2 (en) * 2005-12-07 2014-12-18 Basilea Pharmaceutica Ag Useful combinations of monobactam antibiotics with beta-lactamase inhibitors
CA2680018C (en) * 2007-03-23 2014-01-07 Basilea Pharmaceutica Ag Combination medicaments for treating bacterial infections
WO2009114921A1 (en) * 2008-03-17 2009-09-24 Dmitrienko Gary I INHIBITORS OF CLASS B AND CLASS D β-LACTAMASES
SG187757A1 (en) 2010-08-10 2013-03-28 Rempex Pharmaceuticals Inc Cyclic boronic acid ester derivatives and therapeutic uses thereof
WO2013033461A1 (en) 2011-08-31 2013-03-07 Rempex Pharmaceuticals, Inc. Heterocyclic boronic acid ester derivatives and therapeutic uses thereof
UY34585A (es) 2012-01-24 2013-09-02 Aicuris Gmbh & Co Kg Compuestos b-lactámicos sustituidos con amidina, su preparación y uso
US9156858B2 (en) 2012-05-23 2015-10-13 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
US10561675B2 (en) 2012-06-06 2020-02-18 Rempex Pharmaceuticals, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof
CN102757405B (zh) * 2012-07-25 2014-04-16 山东理工大学 含噻二唑的香兰素衍生物、其制备方法及其用途
US9241947B2 (en) 2013-01-04 2016-01-26 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
EP2941246A4 (en) 2013-01-04 2016-12-21 Rempex Pharmaceuticals Inc BORONIC ACID DERIVATIVES AND THEIR THERAPEUTIC USES
US9101638B2 (en) 2013-01-04 2015-08-11 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
US9132140B2 (en) 2013-01-04 2015-09-15 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
LT3140310T (lt) 2014-05-05 2019-11-25 Rempex Pharmaceuticals Inc Boronato druskų sintezė ir jų panaudojimas
WO2015171398A1 (en) 2014-05-05 2015-11-12 Rempex Pharmaceuticals, Inc. Salts and polymorphs of cyclic boronic acid ester derivatives and therapeutic uses thereof
KR20170007448A (ko) 2014-05-19 2017-01-18 렘펙스 파머수티클스 인코퍼레이티드 보론산 유도체 및 그의 치료적 용도
CA2952968A1 (en) 2014-07-01 2016-01-07 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
WO2016081297A1 (en) 2014-11-18 2016-05-26 Rempex Pharmaceuticals, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof
EP3233869B1 (en) 2014-12-19 2019-09-25 Rempex Pharmaceuticals, Inc. Apparatus and continuous flow process for production of boronic acid derivatives
WO2016149393A1 (en) 2015-03-17 2016-09-22 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
EP3478693B1 (en) 2016-06-30 2021-07-21 Qpex Biopharma, Inc. Boronic acid derivatives and therapeutic uses thereof
CN107641119B (zh) * 2016-07-21 2019-11-08 中国科学院上海药物研究所 单环β-内酰胺-铁载体轭合物及其制备方法和用途
KR20190092566A (ko) 2016-12-21 2019-08-07 아이쿠리스 게엠베하 운트 코. 카게 항생제 내성 박테리아 균주에 의한 감염을 위한 아미딘 치환된 β-락탐 화합물 및 β-락타마제 억제제를 사용하는 조합 요법
BR112020007138B1 (pt) 2017-10-11 2023-03-21 Qpex Biopharma, Inc Derivados de ácido borônico, métodos de síntese, composição farmacêutica e uso dos mesmos
EP3747883A4 (en) 2018-01-29 2020-12-16 Medshine Discovery Inc. B-LACTAM MONOCYCLIC COMPOUND FOR TREATMENT OF BACTERIAL INFECTION
CA3097127A1 (en) 2018-04-20 2019-10-24 Qpex Biopharma, Inc. Boronic acid derivatives and therapeutic uses thereof
CN113227088B (zh) 2018-12-18 2022-05-31 南京明德新药研发有限公司 单环β-内酰胺化合物在制药中的应用
SI25892A (sl) * 2019-09-05 2021-03-31 Gorenje Gospodinjski Aparati, D.O.O. Pralni stroj, ki se polni s sprednje strani, z električnim svetlobnim telesom
JP7630179B2 (ja) * 2019-09-11 2025-02-17 テンノア・セラピューティクス・（スージョウ）・リミテッド 細菌感染症を治療するためのペナム誘導体
US12516049B2 (en) 2019-11-22 2026-01-06 Suzhou Erye Pharmaceutical Co., Ltd Sulfonylurea ring substituted monocyclic β-lactam antibiotics
EP4079305A4 (en) 2019-12-19 2024-01-10 Shenzhen Optimum Biological Technology Co., Ltd APPLICATION OF A COMPOUND IN THE PREPARATION OF DRUG
CN113754651B (zh) * 2020-06-02 2023-04-18 中国医学科学院医药生物技术研究所 一种β-内酰胺化合物、其用途及其制备方法
MA62917B1 (fr) 2021-03-31 2025-11-28 Fedora Pharmaceuticals Inc. Composés de lactivicine, leur préparation et leur utilisation en tant qu'agents antibactériens
EP4387613A4 (en) * 2021-08-20 2026-01-14 Univ Notre Dame Du Lac MONOCYCLIC BETA-LACTAM CONJUGATES AND SIDEROPHORE MIMETIC COMPOUNDS
CN115304594B (zh) 2022-10-12 2023-02-14 苏州二叶制药有限公司 磺酰脲环取代的化合物的盐型及其晶型

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Also Published As

Publication number Publication date
DE60111757D1 (de) 2005-08-04
CZ2003606A3 (cs) 2003-08-13
HUP0301025A2 (hu) 2004-04-28
US20040019203A1 (en) 2004-01-29
CA2422375A1 (en) 2002-03-21
KR20030039369A (ko) 2003-05-17
PL218196B1 (pl) 2014-10-31
ES2244666T3 (es) 2005-12-16
DE60111757T2 (de) 2006-04-27
HK1054377A1 (en) 2003-11-28
NO324946B1 (no) 2008-01-07
SK2462003A3 (en) 2003-09-11
NO20031162D0 (no) 2003-03-13
PL360537A1 (en) 2004-09-06
US6916803B2 (en) 2005-07-12
AU1261402A (en) 2002-03-26
CN1189469C (zh) 2005-02-16
HUP0301025A3 (en) 2009-03-30
NO20031162L (no) 2003-03-13
NZ524292A (en) 2004-09-24
DK1322648T3 (da) 2005-10-31
EP1322648A1 (en) 2003-07-02
JP2004509122A (ja) 2004-03-25
AU2002212614B2 (en) 2006-12-07
WO2002022613A1 (en) 2002-03-21
IL154593A (en) 2008-06-05
KR100854810B1 (ko) 2008-08-27
CZ304586B6 (cs) 2014-07-23
CN1458932A (zh) 2003-11-26
CA2422375C (en) 2011-03-15
IL154593A0 (en) 2003-09-17
EP1322648B1 (en) 2005-06-29
PT1322648E (pt) 2005-11-30
ZA200302085B (en) 2004-03-15
ATE298750T1 (de) 2005-07-15

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B11D Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time