BR0110060A - Forma de administração farmacêutica transdérmica ou transmucosa para o tratamento da dependência de nicotina ou para desacostumar fumantes e uso de forma de administração - Google Patents
Forma de administração farmacêutica transdérmica ou transmucosa para o tratamento da dependência de nicotina ou para desacostumar fumantes e uso de forma de administraçãoInfo
- Publication number
- BR0110060A BR0110060A BR0110060-2A BR0110060A BR0110060A BR 0110060 A BR0110060 A BR 0110060A BR 0110060 A BR0110060 A BR 0110060A BR 0110060 A BR0110060 A BR 0110060A
- Authority
- BR
- Brazil
- Prior art keywords
- dosage form
- treatment
- nicotine
- smokers
- transdermal
- Prior art date
Links
- 206010057852 Nicotine dependence Diseases 0.000 title abstract 3
- 208000025569 Tobacco Use disease Diseases 0.000 title abstract 3
- 239000002552 dosage form Substances 0.000 title 2
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 abstract 3
- 239000000126 substance Substances 0.000 abstract 3
- 239000013543 active substance Substances 0.000 abstract 2
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 229960002715 nicotine Drugs 0.000 abstract 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 abstract 1
- 230000000391 smoking effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Dermatology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"FORMA DE ADMINISTRAçãO FARMACêUTICA TRANSDéRMICA OU TRANSMUCOSA PARA O TRATAMENTO DA DEPENDêNCIA DE NICOTINA OU PARA DESACOSTUMAR FUMANTES E USO DE FORMA DE ADMINISTRAçãO". A presente invenção trata de uma forma de administração farmacêutica transdérmica ou transmucosa para o tratamento da dependência de nicotina ou para desacostumar fumantes, que compreende nicotina, um sal de nicotina, um derivado de nicotina ou de uma substância nicotinérgica em combinação com pelo menos uma substância ativa adicional, e é caracterizada pelo fato de que como substância (s) ativa (s) adicional (ais) compreende pelo menos uma substância que atua no sistema nervoso central.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10018834A DE10018834A1 (de) | 2000-04-15 | 2000-04-15 | Transdermale oder transmucosale Darreichungsformen mit einer nicotinhaltigen Wirkstoffkombination zur Raucherentwöhnung |
| PCT/EP2001/003712 WO2001080837A2 (de) | 2000-04-15 | 2001-04-02 | Transdermale oder transmucosale darreichungsformen mit einer nicotinhaltigen wirkstoffkombination zur raucherentwöhnung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0110060A true BR0110060A (pt) | 2003-07-15 |
Family
ID=7638944
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0110060-2A BR0110060A (pt) | 2000-04-15 | 2001-04-02 | Forma de administração farmacêutica transdérmica ou transmucosa para o tratamento da dependência de nicotina ou para desacostumar fumantes e uso de forma de administração |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20030049308A1 (pt) |
| EP (1) | EP1274405B1 (pt) |
| JP (1) | JP2004501090A (pt) |
| KR (1) | KR100601901B1 (pt) |
| CN (1) | CN1423556A (pt) |
| AR (1) | AR028327A1 (pt) |
| AT (1) | ATE268168T1 (pt) |
| AU (1) | AU5624601A (pt) |
| BR (1) | BR0110060A (pt) |
| CA (1) | CA2404581A1 (pt) |
| DE (2) | DE10018834A1 (pt) |
| DK (1) | DK1274405T3 (pt) |
| ES (1) | ES2220772T3 (pt) |
| HU (1) | HUP0300048A3 (pt) |
| IL (1) | IL152152A0 (pt) |
| MX (1) | MXPA02009104A (pt) |
| NZ (1) | NZ521155A (pt) |
| PL (1) | PL358212A1 (pt) |
| RU (1) | RU2301671C2 (pt) |
| WO (1) | WO2001080837A2 (pt) |
| ZA (1) | ZA200206758B (pt) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10224612A1 (de) * | 2002-06-04 | 2003-12-24 | Lohmann Therapie Syst Lts | Wirkstoffhaltige filmförmige Zubereitungen mit verbesserter chemischer Stabilität, und Verfahren zu deren Herstellung |
| AU2003268026A1 (en) * | 2002-07-30 | 2004-02-16 | Peter Migaly | Combination therapy for depression, prevention of suicide, and varous medical and psychiatric conditions |
| DE10256775A1 (de) * | 2002-12-05 | 2004-06-24 | Lts Lohmann Therapie-Systeme Ag | Filmförmige Zubereitungen zur transmucosalen Verabreichung von Nicotin, sowie Verfahren zu deren Herstellung |
| AR042806A1 (es) | 2002-12-27 | 2005-07-06 | Otsuka Pharma Co Ltd | Combinacion de derivados de carboestirilo e inhibidores de la reabsorcion de serotonina para el tratamiento de trastornos del animo |
| KR100858852B1 (ko) | 2002-12-27 | 2008-09-17 | 오쓰까 세이야꾸 가부시키가이샤 | 기분 장애 치료용 카르보스티릴 유도체 및 세로토닌 재흡수억제제 |
| DE10354894A1 (de) * | 2003-11-24 | 2005-07-07 | Hf Arzneimittelforschung Gmbh | Orale Formulierungen des Desoxypeganins und deren Anwendungen |
| DE102004019916A1 (de) * | 2004-04-21 | 2005-11-17 | Grünenthal GmbH | Gegen Missbrauch gesichertes wirkstoffhaltiges Pflaster |
| US20050277626A1 (en) * | 2004-05-27 | 2005-12-15 | Neurocure Ltd. | Methods and compositions for treatment of nicotine dependence and dementias |
| DE102005007859A1 (de) * | 2005-02-21 | 2006-08-24 | Lts Lohmann Therapie-Systeme Ag | Vefahren für eine medikamentöse Kombinations-Behandlung, sowie hierfür geeignete Arzneimittel-Kombinationen |
| DE102005010255A1 (de) | 2005-03-07 | 2006-09-14 | Lts Lohmann Therapie-Systeme Ag | Faserfreies transdermales therapeutisches System und Verfahren zu seiner Herstellung |
| EP1993509A2 (en) | 2006-02-17 | 2008-11-26 | Novartis AG | Disintegrable oral films |
| DE102006027792A1 (de) * | 2006-06-16 | 2007-12-20 | Lts Lohmann Therapie-Systeme Ag | Antidepressiva-Kombinations-Wafer |
| DE102006027795A1 (de) * | 2006-06-16 | 2007-12-20 | Lts Lohmann Therapie-Systeme Ag | Raucherentwöhnungs-Kombinationswafer |
| US8956602B2 (en) * | 2006-12-05 | 2015-02-17 | Landec, Inc. | Delivery of drugs |
| WO2008112124A2 (en) | 2007-03-07 | 2008-09-18 | Novartis Ag | Orally administrable films |
| CL2008003507A1 (es) * | 2007-11-26 | 2009-11-27 | Neuroderm Ltd | Composicion farmaceutica que comprende nicotina y un inhibidor de la desensibilizacion del receptor de acetilcolina nicotinico (nachr) opipramol; kit farmaceutico; dispositivo medico; y uso para tratar una enfermedad o trastorno del sistema nervioso central o periferico. |
| FR2926221A1 (fr) * | 2008-01-14 | 2009-07-17 | Tassin Thomas | Compositions permettant la reproduction artificielle des conditions pharmacologiques de la dependance aux drogues addictives telles que opiaces, psychostimulants, tabac et alcool, par la combinaison de nicotine et d'un ligand. |
| WO2014105783A1 (en) * | 2012-12-28 | 2014-07-03 | Noven Pharmaceuticals, Inc. | Compositions and methods for transdermal delivery of amphetamine and clonidine |
| WO2014145045A1 (en) * | 2013-03-15 | 2014-09-18 | Tonix Pharmaceuticals, Inc. | Compositions and methods for transmucosal absorption |
| US12459965B2 (en) | 2017-10-09 | 2025-11-04 | Compass Pathfinder Limited | Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| US12433904B2 (en) | 2019-04-17 | 2025-10-07 | Compass Pathfinder Limited | Methods for treating anxiety disorders, headache disorders, and eating disorders with psilocybin |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2265364B1 (pt) * | 1974-03-29 | 1977-11-04 | Creat | |
| CH643260A5 (fr) * | 1980-05-02 | 1984-05-30 | Nestle Sa | 1-allyl-3-butyl-8-methylxanthine, procede de preparation et utilisation dans un medicament. |
| US4385053A (en) * | 1981-03-11 | 1983-05-24 | Barry Reisberg | Treatment for human memory impairment associated with aging |
| US5783207A (en) * | 1985-05-01 | 1998-07-21 | University Of Utah Research Foundation | Selectively removable nicotine-containing dosage form for use in the transmucosal delivery of nicotine |
| GB8612366D0 (en) * | 1986-05-21 | 1986-06-25 | Erba Farmitalia | Ergoline esters |
| US5656286A (en) * | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| US5059600A (en) * | 1989-03-31 | 1991-10-22 | Yale University | Treating habit disorders |
| US5219858A (en) * | 1990-03-27 | 1993-06-15 | Parnell Pharmaceuticals, Inc. | Method and compositions for effecting withdrawal from drug dependency |
| CA2075517C (en) * | 1992-04-01 | 1997-03-11 | John Wick | Transdermal patch incorporating a polymer film incorporated with an active agent |
| DE4301782C1 (de) * | 1993-01-23 | 1994-08-25 | Lohmann Therapie Syst Lts | Verwendung von Galanthamin zur Behandlung der Nicotinabhängigkeit |
| DE69420746T2 (de) * | 1994-06-02 | 2000-06-29 | Dan Riga | Arzneimittel gegen stress, beeinträchtigung und altwerden und verfahren zu ihrer herstellung |
| AU2703795A (en) * | 1994-06-23 | 1996-01-19 | Procter & Gamble Company, The | Treatment of nicotine craving and/or smoking withdrawal symptoms with a transdermal or transmucosal composition containing nicotine and caffeine or xanthine |
| DE19527925C2 (de) * | 1995-07-29 | 1997-07-03 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit einer trennmittelbeschichteten Schutzschicht |
| CA2220768A1 (en) * | 1996-03-13 | 1997-09-18 | Yale University | Smoking cessation treatments using naltrexone and related compounds |
| US6054492A (en) * | 1996-09-09 | 2000-04-25 | Supratek Pharma Inc. | Fluorinated copolymeric pharmaceutical adjuncts |
| AU6250299A (en) * | 1998-09-24 | 2000-04-10 | Algos Pharmaceutical Corporation | Method for reducing nicotine dependency |
| US6224897B1 (en) * | 1998-09-29 | 2001-05-01 | Novartis Consumer Health S.A. | Methods to abate the use of tobacco by humans |
| US6121289A (en) * | 1998-10-09 | 2000-09-19 | Theramax, Inc. | Method for enhanced brain delivery of nicotinic antagonist |
| US6475514B1 (en) * | 1998-12-03 | 2002-11-05 | Andrew Blitzer | Athletic patch |
| PL195871B1 (pl) * | 1998-12-18 | 2007-11-30 | Alza Corp | Urządzenie do przezskórnego dostarczania nikotyny |
| CN1239656A (zh) * | 1999-02-10 | 1999-12-29 | 重庆医科大学 | 戒烟用复方烟碱与可乐定透皮贴剂 |
| IL137937A0 (en) * | 1999-08-27 | 2001-10-31 | Pfizer Prod Inc | A pharmaceutical composition for the prevention and treatment of nicotine addiction in a mammal |
-
2000
- 2000-04-15 DE DE10018834A patent/DE10018834A1/de not_active Ceased
-
2001
- 2001-04-02 CN CN01807994A patent/CN1423556A/zh active Pending
- 2001-04-02 KR KR1020027011637A patent/KR100601901B1/ko not_active Expired - Fee Related
- 2001-04-02 ES ES01929488T patent/ES2220772T3/es not_active Expired - Lifetime
- 2001-04-02 HU HU0300048A patent/HUP0300048A3/hu unknown
- 2001-04-02 AU AU5624601A patent/AU5624601A/xx active Pending
- 2001-04-02 NZ NZ521155A patent/NZ521155A/en not_active Application Discontinuation
- 2001-04-02 AT AT01929488T patent/ATE268168T1/de not_active IP Right Cessation
- 2001-04-02 DK DK01929488T patent/DK1274405T3/da active
- 2001-04-02 IL IL15215201A patent/IL152152A0/xx unknown
- 2001-04-02 CA CA002404581A patent/CA2404581A1/en not_active Abandoned
- 2001-04-02 DE DE50102481T patent/DE50102481D1/de not_active Expired - Lifetime
- 2001-04-02 RU RU2002123887/15A patent/RU2301671C2/ru not_active IP Right Cessation
- 2001-04-02 US US10/257,564 patent/US20030049308A1/en not_active Abandoned
- 2001-04-02 EP EP01929488A patent/EP1274405B1/de not_active Expired - Lifetime
- 2001-04-02 BR BR0110060-2A patent/BR0110060A/pt not_active IP Right Cessation
- 2001-04-02 MX MXPA02009104A patent/MXPA02009104A/es unknown
- 2001-04-02 PL PL01358212A patent/PL358212A1/xx not_active Application Discontinuation
- 2001-04-02 JP JP2001577936A patent/JP2004501090A/ja not_active Withdrawn
- 2001-04-02 WO PCT/EP2001/003712 patent/WO2001080837A2/de not_active Ceased
- 2001-04-11 AR ARP010101728A patent/AR028327A1/es unknown
-
2002
- 2002-08-23 ZA ZA200206758A patent/ZA200206758B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR100601901B1 (ko) | 2006-07-14 |
| MXPA02009104A (es) | 2003-03-12 |
| CA2404581A1 (en) | 2002-09-26 |
| US20030049308A1 (en) | 2003-03-13 |
| DK1274405T3 (da) | 2004-10-11 |
| DE10018834A1 (de) | 2001-10-25 |
| CN1423556A (zh) | 2003-06-11 |
| AR028327A1 (es) | 2003-05-07 |
| HUP0300048A2 (hu) | 2003-06-28 |
| EP1274405A2 (de) | 2003-01-15 |
| DE50102481D1 (de) | 2004-07-08 |
| ZA200206758B (en) | 2003-10-01 |
| JP2004501090A (ja) | 2004-01-15 |
| KR20030025909A (ko) | 2003-03-29 |
| HUP0300048A3 (en) | 2005-04-28 |
| HK1051495A1 (en) | 2003-08-08 |
| NZ521155A (en) | 2006-02-24 |
| AU5624601A (en) | 2001-11-07 |
| WO2001080837A3 (de) | 2002-02-21 |
| ATE268168T1 (de) | 2004-06-15 |
| IL152152A0 (en) | 2003-05-29 |
| WO2001080837A2 (de) | 2001-11-01 |
| ES2220772T3 (es) | 2004-12-16 |
| EP1274405B1 (de) | 2004-06-02 |
| RU2002123887A (ru) | 2004-03-10 |
| RU2301671C2 (ru) | 2007-06-27 |
| PL358212A1 (en) | 2004-08-09 |
| AU2001256246B2 (en) | 2005-03-03 |
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