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BR0008205A - Vetores e vacinas a base de adenovirus porcinos recombinados - Google Patents

Vetores e vacinas a base de adenovirus porcinos recombinados

Info

Publication number
BR0008205A
BR0008205A BR0008205-8A BR0008205A BR0008205A BR 0008205 A BR0008205 A BR 0008205A BR 0008205 A BR0008205 A BR 0008205A BR 0008205 A BR0008205 A BR 0008205A
Authority
BR
Brazil
Prior art keywords
adenovirus
porcine adenovirus
porcine
vivo
nucleotide sequence
Prior art date
Application number
BR0008205-8A
Other languages
English (en)
Inventor
Marc Eloit
Bernard Georges Klonjkowski
Original Assignee
Merial Sas
Envt Toulouse
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Sas, Envt Toulouse filed Critical Merial Sas
Publication of BR0008205A publication Critical patent/BR0008205A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Patente de Invenção: "VETORES E VACINAS à BASE DE ADENOVìRUS PORCINOS RECOMBINADOS". Adenovírus porcino recombinado e replicante in vivo, caracterizado pelo fato de que ele compreende uma sequencia nucleotídica heteróloga inserida no genoma do adenovirus porcino em condições que permitem que esse último se replique in vivo e expresse a seq³ência nucleotídica heteróloga inserida, e pelo fato de que o genoma de adenovirus provém de um adenovírus de sorotipo 3 ou 5 (PAV-3 ou PAV-5). A inserção é notadamente em uma zona não essencial da região E3, de preferência com uma deleção dessa zona. Vacina recombinada porcina que compreende um tal adenovírus porcino. Vetor adenovírus porcino de sorotípo 3 ou 5, ao mesmo tempo replicante in vivo e deletado em uma região nao essencial de seu genoma. Fragmento de DNA que compreende a totalidade ou parte da seq³ência nucleotídica referenciada SEQ ID NO: S.
BR0008205-8A 1999-02-11 2000-02-08 Vetores e vacinas a base de adenovirus porcinos recombinados BR0008205A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9901813A FR2789695B1 (fr) 1999-02-11 1999-02-11 Vecteurs et vaccins viraux a base d'adenovirus porcins recombines et replicatifs
PCT/FR2000/000294 WO2000047756A1 (fr) 1999-02-11 2000-02-08 Vecteurs et vaccins viraux a base d'adenovirus porcins recombines

Publications (1)

Publication Number Publication Date
BR0008205A true BR0008205A (pt) 2002-04-02

Family

ID=9542037

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0008205-8A BR0008205A (pt) 1999-02-11 2000-02-08 Vetores e vacinas a base de adenovirus porcinos recombinados

Country Status (16)

Country Link
US (1) US7109025B1 (pt)
EP (1) EP1151121B1 (pt)
JP (1) JP2002537766A (pt)
KR (1) KR100818673B1 (pt)
CN (2) CN1869243B (pt)
AT (1) ATE316580T1 (pt)
AU (1) AU781195B2 (pt)
BR (1) BR0008205A (pt)
CA (1) CA2362454C (pt)
DE (1) DE60025701T2 (pt)
DK (1) DK1151121T3 (pt)
ES (1) ES2258970T3 (pt)
FR (1) FR2789695B1 (pt)
MX (1) MXPA01008069A (pt)
PL (1) PL205524B1 (pt)
WO (1) WO2000047756A1 (pt)

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EP0839912A1 (en) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
FR2772047B1 (fr) 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
EP1157121B1 (en) * 1999-03-08 2013-04-24 Boehringer Ingelheim Vetmedica GmbH Prrsv replicon
JP4778620B2 (ja) * 1999-04-22 2011-09-21 ユナイテッド ステイツ デパートメント オブ アグリカルチャー 分離株ｊａ−１４２に基づく、豚繁殖・呼吸障害症候群ワクチン
EP1311698A2 (en) * 2000-05-03 2003-05-21 University Of Guelph Porcine adenovirus type 5 vector and vaccine
MXPA03008810A (es) 2001-03-27 2004-02-17 Univ Saskatchewan Metodos para cultivar circovirus.
US7906311B2 (en) 2002-03-20 2011-03-15 Merial Limited Cotton rat lung cells for virus culture
EP1781327A4 (en) 2004-06-18 2009-02-25 Univ Minnesota IDENTIFICATION OF VIRAL INFECTED AND VACCINATED ORGANISMS
US7632636B2 (en) * 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
UA95602C2 (ru) 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Иммуногенная композиция цвс2 и способы приготовления такой композиции
US7833707B2 (en) 2004-12-30 2010-11-16 Boehringer Ingelheim Vetmedica, Inc. Methods of overexpression and recovery of porcine circovirus type 2 ORF2
US7700285B1 (en) 2005-12-29 2010-04-20 Boehringer Ingelheim Vetmedica, Inc. PCV2 immunogenic compositions and methods of producing such compositions
PL2369001T3 (pl) 2005-06-24 2017-06-30 Regents Of The University Of Minnesota Wirusy PRRS, ich klony zakaźne, mutanty i sposoby stosowania
ES2572736T3 (es) 2005-12-29 2016-06-02 Boehringer Ingelheim Vetmedica, Inc. Uso de una composición inmunógena para atenuar síntomas clínicos en cerdos
BR122015028489B1 (pt) 2005-12-29 2021-10-13 Boehringer Ingelheim Animal Health Usa Inc Vacina de combinação multivalente contra pcv2, bem como uso de uma proteína orf2 na preparação da mesma
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AU2007333857B2 (en) * 2006-12-15 2014-05-15 Boehringer Ingelheim Animal Health USA Inc. Treatment of pigs with PCV2 antigen
EP1941903A1 (en) 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxis and treatment of PRDC
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KR20100103535A (ko) * 2007-12-31 2010-09-27 베링거잉겔하임베트메디카인코퍼레이티드 외래 아미노산 삽입물을 갖는 ｐｃｖ２ ｏｒｆ２ 바이러스 유사 입자
WO2009126356A2 (en) 2008-01-23 2009-10-15 Boehringer Ingelheim Vetmedica, Inc. Pcv2 mycoplasma hyopneumoniae immunogenic compositions and methods of producing such compositions
US8444989B1 (en) * 2008-04-18 2013-05-21 Boehringer Ingelheim Vetmedica Gmbh One dose vaccination against mycoplasma infections of pigs
AU2009285843B2 (en) * 2008-08-25 2014-07-17 Boehringer Ingelheim Vetmedica Inc Vaccine against Highly Pathogenic Porcine Reproductive and Respiratory Syndrome (HP PRRS)
AU2009100018B4 (en) * 2008-10-15 2009-09-03 Australasian Pork Research Institute Ltd A Method of vaccination
US20100150959A1 (en) * 2008-12-15 2010-06-17 Vectogen Pty Ltd. PCV 2-Based Methods and Compositions for the Treatment of Pigs
TWI627281B (zh) 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物
UA117272C2 (uk) 2011-02-17 2018-07-10 Бьорінгер Інгельхайм Ветмедіка Гмбх Новий європейський штам prrsv
CN103370077B (zh) 2011-02-17 2016-10-26 贝林格尔.英格海姆维特梅迪卡有限公司 猪繁殖与呼吸综合征病毒的商业化规模生产方法
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
WO2013017568A1 (en) 2011-07-29 2013-02-07 Boehringer Ingelheim Vetmedica Gmbh INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF
CN102766604B (zh) * 2012-06-19 2013-06-05 河南农业大学 一种猪流感病毒毒株及其应用
CN105073130A (zh) 2013-03-15 2015-11-18 勃林格殷格翰动物保健公司 猪生殖与呼吸综合征病毒、组合物、疫苗及使用方法
ES2882374T3 (es) 2013-05-08 2021-12-01 Pharmgate Biologics Inc Vacuna para PCV2 y micoplasma
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CN105368796A (zh) * 2015-09-09 2016-03-02 河南农业大学 一种表达ppv vp2基因和猪il-18基因的重组猪伪狂犬病毒株
EA201991065A1 (ru) * 2016-11-03 2019-11-29 Вакцина против свиного парвовируса
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CN112834744A (zh) * 2020-12-31 2021-05-25 天津瑞普生物技术股份有限公司 一种猪群体内腺病毒3型中和抗体阳性率的elisa试剂盒及其检测方法

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Also Published As

Publication number Publication date
CN1869243B (zh) 2016-01-20
FR2789695B1 (fr) 2003-03-07
JP2002537766A (ja) 2002-11-12
DK1151121T3 (da) 2006-05-29
US7109025B1 (en) 2006-09-19
CN1343257A (zh) 2002-04-03
KR20020013502A (ko) 2002-02-20
AU781195B2 (en) 2005-05-12
EP1151121B1 (fr) 2006-01-25
WO2000047756A1 (fr) 2000-08-17
EP1151121A1 (fr) 2001-11-07
CA2362454A1 (en) 2000-08-17
KR100818673B1 (ko) 2008-04-01
FR2789695A1 (fr) 2000-08-18
DE60025701T2 (de) 2006-10-19
PL205524B1 (pl) 2010-04-30
DE60025701D1 (de) 2006-04-13
CN1262664C (zh) 2006-07-05
MXPA01008069A (es) 2003-09-10
CA2362454C (en) 2011-12-20
PL350182A1 (en) 2002-11-18
ATE316580T1 (de) 2006-02-15
AU2553700A (en) 2000-08-29
ES2258970T3 (es) 2006-09-16
CN1869243A (zh) 2006-11-29

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15V Prolongation of time limit allowed

Free format text: RECONHECIDO O OBSTACULO ADMINISTRATIVO E DEVOLVIDO O PRAZO DE 23 (VINTE E TRES) DIAS, NOS TERMOS DO ARTIGO 221 PARAGRAFO 2O DA LPI E DA RESOLUCAO 116/04.

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O C/C 11 E 8O C/C 13 DA LPI.

B12B Appeal against refusal [chapter 12.2 patent gazette]