BG46003A3 - Метод за получаване на 1-(хидроксистирил) -5н-2,3-бензодиазепинови съединения - Google Patents

Метод за получаване на 1-(хидроксистирил) -5н-2,3-бензодиазепинови съединения

Info

Publication number: BG46003A3
Authority: BG; Bulgaria
Prior art keywords: hydroxystyryl; preparation; benzodiazepine compounds; polar; compounds
Prior art date: 1986-05-21

Application number

BG079835A

Other languages

Bulgarian (bg)

English (en)

Inventor

Tibor Lang

Jeno Korosi

Gyorgy Rabloczky

Tamas Hamori

Maria Kuhar

Istvan Polgari

Istvan Elekes

Gabor Zolyomi

Krisztina Heltai

Judit Sarossy

Zsuzsanna Lang

Imre Moravcsik

Original Assignee

Egis Gyogyszergyar Rt.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-05-21

Filing date

1987-05-21

Publication date

1989-09-15

1987-05-21 Application filed by Egis Gyogyszergyar Rt. filed Critical Egis Gyogyszergyar Rt.

1989-09-15 Publication of BG46003A3 publication Critical patent/BG46003A3/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/02—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

BG079835A 1986-05-21 1987-05-21 Метод за получаване на 1-(хидроксистирил) -5н-2,3-бензодиазепинови съединения BG46003A3 (bg)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU862140A HU195788B (en)	1986-05-21	1986-05-21	Process for producing 1-/hydroxy-stiryl/-5h-2,3-benzobiazepines and pharmaceutical compositions containing them

Publications (1)

Publication Number	Publication Date
BG46003A3 true BG46003A3 (bg)	1989-09-15

Family

ID=10957976

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG079835A BG46003A3 (bg)	1986-05-21	1987-05-21	Метод за получаване на 1-(хидроксистирил) -5н-2,3-бензодиазепинови съединения

Country Status (24)

Country	Link
US (1)	US4840948A (it)
JP (1)	JPS6322082A (it)
AT (1)	AT395009B (it)
BE (1)	BE1000573A4 (it)
BG (1)	BG46003A3 (it)
CA (1)	CA1280748C (it)
CH (1)	CH671226A5 (it)
CS (1)	CS262690B2 (it)
DD (1)	DD268943A5 (it)
DE (1)	DE3717080C2 (it)
DK (1)	DK258187A (it)
ES (1)	ES2005582A6 (it)
FI (1)	FI91964C (it)
FR (1)	FR2599034B1 (it)
GB (1)	GB2190677B (it)
HU (1)	HU195788B (it)
IL (1)	IL82613A (it)
IT (1)	IT1205665B (it)
NL (1)	NL8701213A (it)
PL (1)	PL147687B1 (it)
PT (1)	PT84923B (it)
SE (1)	SE468560B (it)
SU (1)	SU1503681A3 (it)
YU (1)	YU46675B (it)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5380721A (en) *	1990-09-10	1995-01-10	Sterling Winthrop Inc.	Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents
HU219778B (hu) *	1990-12-21	2001-07-30	Gyógyszerkutató Intézet Közös Vállalat	Eljárás N-acil-2,3-benzodiazepin-származékok, savaddíciós sóik és az ezeket tartalmazó gyógyászati készítmények előállítására, valamint a vegyületek egy csoportja, és az ezeket tartalmazó gyógyászati készítmények
DE69612413T2 (de) *	1995-02-09	2001-09-27	Egis Gyogyszergyar Rt., Budapest	1-(Hetero)Arylvinyl-5H-2,3-benzodiazepinderivative verwendbar zur Behandlung von Erkrankungen des Zentralnervensystems, sowie Benzopyrylium Intermediate zu ihrer Herstellung
SK283859B6 (sk) *	1995-02-09	2004-03-02	Egis Gy�Gyszergy�R Rt.	1-[2'-(Substituovaný)vinyl]-5H-2,3-benzodiazepínové deriváty, spôsob ich prípravy a medziprodukty na ich prípravu, liečivá ich obsahujúce a ich použitie
HU224435B1 (hu) *	1995-02-09	2005-10-28	EGIS Gyógyszergyár Rt.	Benzodiazepin-származékok, eljárás előállításukra, alkalmazásukra és ezeket tartalmazó gyógyászati készítmények
ES2111493B1 (es) *	1996-02-08	1999-08-01	Egyt Gyogyszervegyeszeti Gyar	Derivados de 1-(2- (vinilo substituido ) ) -5h-2,3-benzo-diazepina, procedimiento para su preparacion, composiciones farmaceuticas que los contienen y utilizaciones correspondientes.
HU227128B1 (en) *	1999-07-07	2010-07-28	Egyt Gyogyszervegyeszeti Gyar	New 2,3-benzodiazepine derivatives
US6864251B2 (en) *	2002-12-03	2005-03-08	Vela Pharmaceuticals, Inc.	Treatment of LTB4-mediated inflammatory disorders with optically-pure (R)-2,3-benzodiazepines
US7022700B2 (en) *	2002-12-03	2006-04-04	Vela Pharmaceuticals, Inc.	Method of increasing neutrophil production using optically-pure (R)-2,3-benzodiazepines
AU2003303312A1 (en) *	2002-12-03	2004-08-30	Vela Pharmaceuticals, Inc.	Pharmaceutical composition of 1-(3-hydroxy-4-methoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5h-2,3-benzodiazepine and uses therof
WO2004050040A2 (en) *	2002-12-03	2004-06-17	Vela Pharmaceuticals, Inc.	Pharmaceutical composition of 1-(3,4-dimethoxyphenyl)-4-methyl-5-ethyl-7-methoxy-8-hydroxy-5h-2,3-benzodiazepine and uses thereof
US6638928B1 (en)	2002-12-03	2003-10-28	Vela Pharmaceuticals, Inc.	Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines
US20040162284A1 (en) *	2003-02-19	2004-08-19	Harris Herbert W.	Method of lowering body temperature with (S) tofisopam
US20040224943A1 (en) *	2003-02-19	2004-11-11	Leventer Steven M.	Method of lowering body temperature with (R) - 2,3-benzodiazepines
HUP0302449A3 (en) *	2003-08-04	2005-06-28	Egis Gyogyszergyar Nyilvanosan	8-chloro-2,3-benzodiazepine derivatives, pharmaceutical compositions containing them and process for producing them

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK118660B (da) *	1966-12-09	1970-09-21	Egyt Gyogyszervegyeszeti Gyar	Analogifremgangsmåde til fremstilling af 1-(3',4'-dimethoxyphenyl)-3-methyl-4-ethyl-6,7-dimethoxy-isoquinolin-N-imid.
HU179018B (en) *	1978-10-19	1982-08-28	Gyogyszerkutato Intezet	Process for producing new 5h-2,3-benzodiazepine derivatives
HU191698B (en) *	1984-07-27	1987-03-30	Gyogyszerkutato Intezet	Process for producing new 1-aryl-5h-2beta-benzodiazepines

1986
- 1986-05-21 HU HU862140A patent/HU195788B/hu not_active IP Right Cessation
1987
- 1987-05-19 CH CH1916/87A patent/CH671226A5/de not_active IP Right Cessation
- 1987-05-20 US US07/051,777 patent/US4840948A/en not_active Expired - Fee Related
- 1987-05-21 IL IL82613A patent/IL82613A/xx unknown
- 1987-05-21 JP JP62124992A patent/JPS6322082A/ja active Pending
- 1987-05-21 YU YU90687A patent/YU46675B/sh unknown
- 1987-05-21 NL NL8701213A patent/NL8701213A/nl not_active Application Discontinuation
- 1987-05-21 GB GB8712005A patent/GB2190677B/en not_active Expired - Lifetime
- 1987-05-21 AT AT0130287A patent/AT395009B/de not_active IP Right Cessation
- 1987-05-21 DE DE3717080A patent/DE3717080C2/de not_active Expired - Fee Related
- 1987-05-21 FR FR8707118A patent/FR2599034B1/fr not_active Expired
- 1987-05-21 PT PT84923A patent/PT84923B/pt not_active IP Right Cessation
- 1987-05-21 PL PL1987265812A patent/PL147687B1/pl unknown
- 1987-05-21 ES ES8701496A patent/ES2005582A6/es not_active Expired
- 1987-05-21 SU SU874203194A patent/SU1503681A3/ru active
- 1987-05-21 CS CS873690A patent/CS262690B2/cs unknown
- 1987-05-21 FI FI872255A patent/FI91964C/fi not_active IP Right Cessation
- 1987-05-21 DK DK258187A patent/DK258187A/da not_active Application Discontinuation
- 1987-05-21 DD DD87303005A patent/DD268943A5/de not_active IP Right Cessation
- 1987-05-21 CA CA000537655A patent/CA1280748C/en not_active Expired - Lifetime
- 1987-05-21 IT IT20619/87A patent/IT1205665B/it active
- 1987-05-21 SE SE8702120A patent/SE468560B/sv not_active IP Right Cessation
- 1987-05-21 BE BE8700571A patent/BE1000573A4/fr not_active IP Right Cessation
- 1987-05-21 BG BG079835A patent/BG46003A3/xx unknown

Also Published As

Publication number	Publication date
YU46675B (sh)	1994-01-20
ATA130287A (de)	1992-01-15
DK258187D0 (da)	1987-05-21
CA1280748C (en)	1991-02-26
IL82613A0 (en)	1987-11-30
CH671226A5 (it)	1989-08-15
DD268943A5 (de)	1989-06-14
FR2599034B1 (fr)	1989-06-09
CS369087A2 (en)	1988-08-16
DE3717080C2 (de)	1996-02-08
PL147687B1 (en)	1989-07-31
BE1000573A4 (fr)	1989-02-07
HU195788B (en)	1988-07-28
HUT44521A (en)	1988-03-28
GB2190677B (en)	1990-01-10
GB8712005D0 (en)	1987-06-24
DK258187A (da)	1987-11-22
FR2599034A1 (fr)	1987-11-27
FI91964B (fi)	1994-05-31
ES2005582A6 (es)	1989-03-16
PT84923A (en)	1987-06-01
FI872255A7 (fi)	1987-11-22
IT8720619A0 (it)	1987-05-21
SU1503681A3 (ru)	1989-08-23
NL8701213A (nl)	1987-12-16
YU90687A (en)	1988-08-31
CS262690B2 (en)	1989-03-14
JPS6322082A (ja)	1988-01-29
FI91964C (fi)	1994-09-12
PL265812A1 (en)	1988-05-12
AT395009B (de)	1992-08-25
DE3717080A1 (de)	1987-11-26
SE8702120D0 (sv)	1987-05-21
PT84923B (pt)	1990-02-08
IT1205665B (it)	1989-03-31
US4840948A (en)	1989-06-20
IL82613A (en)	1991-03-10
GB2190677A (en)	1987-11-25
SE468560B (sv)	1993-02-08
FI872255A0 (fi)	1987-05-21
SE8702120L (sv)	1987-11-22

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