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BG107711A - NEW M-AMINO-PHENYLIMINO-IMIDAZOLIDINE DERIVATIVES FOR TREATMENT OF URIN INCONTINENCE - Google Patents

NEW M-AMINO-PHENYLIMINO-IMIDAZOLIDINE DERIVATIVES FOR TREATMENT OF URIN INCONTINENCE

Info

Publication number
BG107711A
BG107711A BG107711A BG10771103A BG107711A BG 107711 A BG107711 A BG 107711A BG 107711 A BG107711 A BG 107711A BG 10771103 A BG10771103 A BG 10771103A BG 107711 A BG107711 A BG 107711A
Authority
BG
Bulgaria
Prior art keywords
phenylimino
amino
incontinence
urin
treatment
Prior art date
Application number
BG107711A
Other languages
Bulgarian (bg)
Inventor
Pascale Pouzet
Franz Esser
Hisato Kitagawa
Kenji Sakai
Ikunobu Muramatsu
Original Assignee
Boehringer Ingelheim Pharma Gmbh & Co.Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma Gmbh & Co.Kg filed Critical Boehringer Ingelheim Pharma Gmbh & Co.Kg
Publication of BG107711A publication Critical patent/BG107711A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The invention relates to m-amino-phenylimino-imidazolidine derivatives with a novel substituent pattern on the phenyl ring, of general formula or of general formula wherein R1 is F, Cl, Br, CH2F, CF2H or CF3; R2 is NR6R7, R6 being Me, Et, Pr or iPr, and R7 being Me, Et or Pr, and R3, R4 and R5 are each, independently of each other, H, Me, F, Cl, Br, CH2F, CF2H and/or CF3, and if R4 is Me, F, Cl, Br, CH2F, CF2H or CF3, then R1 is additionally also H or Me; and or their pharmaceutically compatible salts, to the use thereof of producing medicaments, especially for treating urinary incontinence and to a method for producing the same. 18 claims
BG107711A 2000-10-14 2003-04-08 NEW M-AMINO-PHENYLIMINO-IMIDAZOLIDINE DERIVATIVES FOR TREATMENT OF URIN INCONTINENCE BG107711A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10051005 2000-10-14
PCT/EP2001/011764 WO2002032876A2 (en) 2000-10-14 2001-10-11 Novel m-amino-phenylimino-imidazolidine derivatives for treating urinary incontinence

Publications (1)

Publication Number Publication Date
BG107711A true BG107711A (en) 2004-02-27

Family

ID=7659815

Family Applications (1)

Application Number Title Priority Date Filing Date
BG107711A BG107711A (en) 2000-10-14 2003-04-08 NEW M-AMINO-PHENYLIMINO-IMIDAZOLIDINE DERIVATIVES FOR TREATMENT OF URIN INCONTINENCE

Country Status (23)

Country Link
EP (1) EP1328517A2 (en)
JP (1) JP2004511547A (en)
KR (1) KR20030046503A (en)
CN (1) CN1471514A (en)
AR (1) AR035923A1 (en)
AU (1) AU2002215943A1 (en)
BG (1) BG107711A (en)
BR (1) BR0114603A (en)
CA (1) CA2425563A1 (en)
CZ (1) CZ20031333A3 (en)
DE (1) DE10150312A1 (en)
EA (1) EA200300460A1 (en)
EC (1) ECSP034517A (en)
EE (1) EE200300177A (en)
HU (1) HUP0302245A3 (en)
IL (1) IL155338A0 (en)
MX (1) MXPA03003162A (en)
NO (1) NO20031697L (en)
PL (1) PL361359A1 (en)
SK (1) SK4342003A3 (en)
WO (1) WO2002032876A2 (en)
YU (1) YU28203A (en)
ZA (1) ZA200302345B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4168086B1 (en) * 2008-04-16 2008-10-22 国立大学法人福井大学 Imidazoline derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2806811A1 (en) * 1978-02-17 1979-08-23 Boehringer Sohn Ingelheim NEW SUBSTITUTED 2-PHENYLIMINO-IMIDAZOLIDINE, THEIR ACID-ADDITIONAL SALTS, THESE MEDICINAL PRODUCTS AND METHOD FOR MANUFACTURING THE SAME
CA1201066A (en) * 1981-11-20 1986-02-25 Alcon Laboratories, Inc. N-¬3,5-dichloro-4-(2-imidazolidinylideneamino)- phenyl|-acetamide solutions for lowering intraocular pressure
DE19514579A1 (en) * 1995-04-20 1996-10-24 Boehringer Ingelheim Kg Use of alpha-1-olone agonists for the treatment of urinary incontinence

Also Published As

Publication number Publication date
NO20031697D0 (en) 2003-04-11
CN1471514A (en) 2004-01-28
EE200300177A (en) 2003-08-15
YU28203A (en) 2006-05-25
NO20031697L (en) 2003-05-26
MXPA03003162A (en) 2004-12-06
ZA200302345B (en) 2004-04-23
WO2002032876A2 (en) 2002-04-25
EP1328517A2 (en) 2003-07-23
CZ20031333A3 (en) 2003-08-13
BR0114603A (en) 2003-10-14
KR20030046503A (en) 2003-06-12
IL155338A0 (en) 2003-11-23
AU2002215943A1 (en) 2002-04-29
PL361359A1 (en) 2004-10-04
AR035923A1 (en) 2004-07-28
HUP0302245A3 (en) 2004-01-28
CA2425563A1 (en) 2002-04-25
WO2002032876A3 (en) 2002-07-18
ECSP034517A (en) 2003-04-25
DE10150312A1 (en) 2002-07-04
HUP0302245A2 (en) 2003-10-28
JP2004511547A (en) 2004-04-15
EA200300460A1 (en) 2004-02-26
SK4342003A3 (en) 2003-10-07

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