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BG105572A - Treatment of tumors by administration of growth hormone releasing compounds and their antagonists - Google Patents

Treatment of tumors by administration of growth hormone releasing compounds and their antagonists

Info

Publication number
BG105572A
BG105572A BG105572A BG10557201A BG105572A BG 105572 A BG105572 A BG 105572A BG 105572 A BG105572 A BG 105572A BG 10557201 A BG10557201 A BG 10557201A BG 105572 A BG105572 A BG 105572A
Authority
BG
Bulgaria
Prior art keywords
tumors
growth hormone
hormone releasing
antagonists
administration
Prior art date
Application number
BG105572A
Other languages
Bulgarian (bg)
English (en)
Inventor
Giampiero Muccioli
Mauro Papotti
Ezio Ghigo
Romano Deghenghi
Original Assignee
Zentaris Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris Ag filed Critical Zentaris Ag
Publication of BG105572A publication Critical patent/BG105572A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/29Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pulmonology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
BG105572A 1998-11-16 2001-06-07 Treatment of tumors by administration of growth hormone releasing compounds and their antagonists BG105572A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/192,406 US6124263A (en) 1998-11-16 1998-11-16 Treatment of tumors by administration of growth hormone releasing compounds and their antagonists
PCT/EP1999/008662 WO2000029011A1 (en) 1998-11-16 1999-11-11 Treatment of tumors by administration of growth hormone releasing compounds and their antagonists

Publications (1)

Publication Number Publication Date
BG105572A true BG105572A (en) 2002-01-31

Family

ID=22709509

Family Applications (1)

Application Number Title Priority Date Filing Date
BG105572A BG105572A (en) 1998-11-16 2001-06-07 Treatment of tumors by administration of growth hormone releasing compounds and their antagonists

Country Status (30)

Country Link
US (1) US6124263A (zh)
EP (1) EP1131083B1 (zh)
JP (1) JP2002529512A (zh)
KR (1) KR100704138B1 (zh)
CN (3) CN100368014C (zh)
AR (1) AR021286A1 (zh)
AT (1) ATE258062T1 (zh)
BG (1) BG105572A (zh)
BR (1) BR9915390A (zh)
CA (1) CA2350914A1 (zh)
CO (1) CO5140111A1 (zh)
CZ (1) CZ20011577A3 (zh)
DE (1) DE69914365T2 (zh)
DK (1) DK1131083T3 (zh)
ES (1) ES2212650T3 (zh)
HK (1) HK1040934A1 (zh)
HU (1) HUP0104374A3 (zh)
IL (1) IL142858A0 (zh)
MX (1) MXPA01004689A (zh)
NO (1) NO20012367L (zh)
NZ (1) NZ511280A (zh)
PL (1) PL347659A1 (zh)
PT (1) PT1131083E (zh)
RU (1) RU2240133C2 (zh)
SK (1) SK6352001A3 (zh)
TR (1) TR200101350T2 (zh)
TW (2) TWI237565B (zh)
UA (1) UA73100C2 (zh)
WO (1) WO2000029011A1 (zh)
ZA (1) ZA200103182B (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6211156B1 (en) * 1999-11-10 2001-04-03 Asta Medica A.G. Peptides for treatment of erectile dysfunction
CU23157A1 (es) * 2001-01-03 2006-07-18 Ct Ingenieria Genetica Biotech COMPOSICION FARMACéUTICA PARA EL TRATAMIENTO DEL DANO TISULAR DEBIDO A FALTA DE IRRIGACION SANGUINEA ARTERIAL
DE10112882A1 (de) * 2001-03-15 2002-09-19 Max Delbrueck Centrum Verwendung von Tryptophan-Derivaten zur spezifischen zytostatischen Behandlung von Serotonin-produzierenden Tumoren
WO2002090387A1 (en) * 2001-05-10 2002-11-14 Queensland University Of Technology Reproductive cancer diagnosis and therapy
EP1312363A1 (en) * 2001-09-28 2003-05-21 Pfizer Products Inc. Methods of treatment and kits comprising a growth hormone secretagogue
TWI331922B (en) 2002-08-09 2010-10-21 Ipsen Pharma Sas Growth hormone releasing peptides
WO2005027913A1 (en) * 2003-09-19 2005-03-31 Pfizer Products Inc. Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and a growth hormone secretagogue
US20050164952A1 (en) * 2004-01-23 2005-07-28 Vital Pharmaceuticals, Inc. Delivery system for growth hormone releasing peptides
EP2021015A2 (en) * 2006-04-28 2009-02-11 The Administrators Of The Tulane Educational Fund Ghrelin/growth hormone releasing peptide/growth hormone secretatogue receptor antagonists and uses thereof
NZ576470A (en) 2006-09-27 2012-09-28 Ipsen Pharma Sas Analogs of ghrelin substituted at the n-terminal
MX2009008561A (es) 2007-02-13 2010-01-15 Helsinn Therapeutics Us Inc Metodo para tratar trastornos proliferativos celulares utilizando secretagogos.
WO2010118309A2 (en) * 2009-04-10 2010-10-14 Board Of Regents, The University Of Texas System Inhibitors of stat3 and uses thereof
US9724381B2 (en) 2009-05-12 2017-08-08 The Administrators Of The Tulane Educational Fund Methods of inhibiting the ghrelin/growth hormone secretatogue receptor pathway and uses thereof
IT1399610B1 (it) * 2010-01-28 2013-04-26 Univ Milano Bicocca Uso di agonisti e antagonisti dei recettori per i growth hormone secretagogues per la prevenzione e il trattamento di convulsioni ed epilessia
WO2020163833A2 (en) 2019-02-08 2020-08-13 United States Government As Represented By The Department Of Veterans Affairs Growth hormone-releasing hormone antagonists and uses thereof
CN118021978A (zh) * 2019-07-18 2024-05-14 迈阿密大学 用于治疗结节病的方法的ghrh拮抗剂

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0173119B1 (ko) * 1989-04-26 1999-02-01 닐 에이. 밴스로우 선형 소마토스타틴 유사체
IT1240643B (it) * 1990-05-11 1993-12-17 Mediolanum Farmaceutici Spa Peptidi biologicamente attivi contenenti in catena 2-alchiltriptofano
GB2244063A (en) * 1990-05-15 1991-11-20 Exxon Research Engineering Co Grease composition containing inorganic compounds
DE69432758T2 (de) * 1993-08-09 2004-02-19 Société de Conseils de Recherches et d'Applications Scientifiques S.A.S. Therapeutisch wirksame peptidderivate
US5550212A (en) * 1993-12-17 1996-08-27 The Administrators Of The Tulane Educational Fund Analogues of hGH-RH(1-29)NH2 having antagonistic activity
US5807985A (en) * 1996-06-11 1998-09-15 Deghenghi; Romano Oligopeptide compounds containing D-2-alkyltryptophan capable of promoting the release of growth hormone
US6063796A (en) * 1997-04-04 2000-05-16 Merck & Co., Inc. Somatostatin agonists

Also Published As

Publication number Publication date
US6124263A (en) 2000-09-26
IL142858A0 (en) 2002-03-10
KR20010089459A (ko) 2001-10-06
ZA200103182B (en) 2001-09-07
TW200530270A (en) 2005-09-16
CN1277840C (zh) 2006-10-04
EP1131083A1 (en) 2001-09-12
CN1594358A (zh) 2005-03-16
CN1895660A (zh) 2007-01-17
DE69914365D1 (de) 2004-02-26
DE69914365T2 (de) 2004-11-04
DK1131083T3 (da) 2004-04-26
CN100368014C (zh) 2008-02-13
CZ20011577A3 (cs) 2002-07-17
TWI237565B (en) 2005-08-11
ES2212650T3 (es) 2004-07-16
CN1326353A (zh) 2001-12-12
EP1131083B1 (en) 2004-01-21
HUP0104374A2 (hu) 2002-04-29
SK6352001A3 (en) 2002-09-10
PL347659A1 (en) 2002-04-22
ATE258062T1 (de) 2004-02-15
KR100704138B1 (ko) 2007-04-09
NO20012367D0 (no) 2001-05-14
CO5140111A1 (es) 2002-03-22
NZ511280A (en) 2002-10-25
CA2350914A1 (en) 2000-05-25
PT1131083E (pt) 2004-06-30
MXPA01004689A (es) 2002-09-18
HK1040934A1 (zh) 2002-06-28
TR200101350T2 (tr) 2001-11-21
NO20012367L (no) 2001-07-09
TWI263642B (en) 2006-10-11
RU2240133C2 (ru) 2004-11-20
AR021286A1 (es) 2002-07-03
UA73100C2 (en) 2005-06-15
WO2000029011A1 (en) 2000-05-25
CN1200726C (zh) 2005-05-11
BR9915390A (pt) 2001-08-07
HUP0104374A3 (en) 2003-03-28
JP2002529512A (ja) 2002-09-10

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