BG104107A - 4-АМИНОПИРОЛ/3,2-d/ ПИРИМИДИНИ КАТО РЕЦЕПТОРНИ АНТАГОНИСТИ НА НЕВРОПЕПТИД Y - Google Patents

4-АМИНОПИРОЛ/3,2-d/ ПИРИМИДИНИ КАТО РЕЦЕПТОРНИ АНТАГОНИСТИ НА НЕВРОПЕПТИД Y Download PDF

Info

Publication number: BG104107A
Authority: BG; Bulgaria
Prior art keywords: hydrogen; methyl; mean; alkyl; phenyl
Prior art date: 1997-08-05

Application number

BG104107A

Other languages

Bulgarian (bg)

English (en)

Inventor

Robert DOW

Marlys Hammond

Original Assignee

Pfizer Products Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-08-05

Filing date

2000-01-26

Publication date

2000-08-31

2000-01-26 Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.

2000-08-31 Publication of BG104107A publication Critical patent/BG104107A/bg

Links

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102400000064 Neuropeptide Y Human genes 0.000 claims abstract description 12
URPYMXQQVHTUDU-OFGSCBOVSA-N nucleopeptide y Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(N)=O)NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CC=1C=CC(O)=CC=1)C1=CC=C(O)C=C1 URPYMXQQVHTUDU-OFGSCBOVSA-N 0.000 claims abstract description 9
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UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 27
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

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Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Child & Adolescent Psychology (AREA)
Hematology (AREA)
Obesity (AREA)
Biomedical Technology (AREA)
Cardiology (AREA)
Endocrinology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

BG104107A 1997-08-05 2000-01-26 4-АМИНОПИРОЛ/3,2-d/ ПИРИМИДИНИ КАТО РЕЦЕПТОРНИ АНТАГОНИСТИ НА НЕВРОПЕПТИД Y BG104107A (bg)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US5473497P	1997-08-05	1997-08-05
PCT/IB1998/001053 WO1999007703A1 (en)	1997-08-05	1998-07-10	4-AMINOPYRROLE(3,2-d) PYRIMIDINES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS

Publications (1)

Publication Number	Publication Date
BG104107A true BG104107A (bg)	2000-08-31

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Country Status (32)

Country	Link
US (1)	US6187778B1 (pt)
EP (1)	EP1003744B1 (pt)
JP (1)	JP3711238B2 (pt)
KR (1)	KR20010022583A (pt)
CN (1)	CN1264381A (pt)
AP (1)	AP9801312A0 (pt)
AT (1)	ATE296825T1 (pt)
AU (1)	AU7927498A (pt)
BG (1)	BG104107A (pt)
BR (1)	BR9811844A (pt)
CA (1)	CA2293621C (pt)
CO (1)	CO4960634A1 (pt)
DE (1)	DE69830409T2 (pt)
EA (1)	EA200000098A1 (pt)
ES (1)	ES2241146T3 (pt)
GT (1)	GT199800114A (pt)
HR (1)	HRP980434A2 (pt)
HU (1)	HUP0002956A3 (pt)
ID (1)	ID24300A (pt)
IL (1)	IL133430A0 (pt)
IS (1)	IS5294A (pt)
MA (1)	MA24629A1 (pt)
NO (1)	NO996178L (pt)
OA (1)	OA11277A (pt)
PA (1)	PA8456601A1 (pt)
PE (1)	PE106199A1 (pt)
PL (1)	PL338575A1 (pt)
SA (1)	SA98190435A (pt)
TN (1)	TNSN98148A1 (pt)
TR (1)	TR200000333T2 (pt)
WO (1)	WO1999007703A1 (pt)
ZA (1)	ZA986968B (pt)

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US6187777B1 (en)	1998-02-06	2001-02-13	Amgen Inc.	Compounds and methods which modulate feeding behavior and related diseases
KR20020047201A (ko) *	1999-09-30	2002-06-21	해피 페너 ; 해리 에이치. 페너 2세	아미노-치환된 피라졸로[1,5-ａ]-1,5-피리미딘 및피라졸로[1,5-ａ]-1,3,5-트리아진
CN1615873A (zh) *	1999-12-24	2005-05-18	阿文蒂斯药物有限公司	氮杂吲哚类化合物
GB0117396D0 (en)	2001-07-17	2001-09-05	Glaxo Group Ltd	Chemical compounds
GB0308208D0 (en)	2003-04-09	2003-05-14	Glaxo Group Ltd	Chemical compounds
US7507740B2 (en)	2004-06-02	2009-03-24	Takeda Pharmaceutical Company Limited	Fused heterocyclic compound
MXPA06014798A (es)	2004-06-17	2007-06-22	Wyeth Corp	Antagonistas del receptor de hormona para liberar gonadotropina.
RU2007101509A (ru)	2004-06-17	2008-07-27	Уайт (Us)	Способ получения антагонистов рецепторов гормона, высвобождающего гонадотропин
MX2007001399A (es) *	2004-08-02	2007-04-18	Osi Pharm Inc	Compuestos que inhiben pirrolopirimidina multi-cinasa aril-amino sustituidas.
MY179032A (en)	2004-10-25	2020-10-26	Cancer Research Tech Ltd	Ortho-condensed pyridine and pyrimidine derivatives (e.g.purines) as protein kinase inhibitors
KR20060087386A (ko)	2005-01-28	2006-08-02	주식회사 대웅제약	신규 벤조이미다졸 유도체 및 이를 함유하는 약제학적조성물
PL1861387T3 (pl) *	2005-01-28	2014-08-29	Dae Woong Pharma	Pochodne benzoimidazolu i ich kompozycje farmaceutyczne
US7538113B2 (en)	2005-02-18	2009-05-26	Wyeth	4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
US7534796B2 (en)	2005-02-18	2009-05-19	Wyeth	Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor
US7582634B2 (en)	2005-02-18	2009-09-01	Wyeth	7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
WO2006108218A1 (en) *	2005-04-15	2006-10-19	Regenertech Pty Limited	Use of neuropeptide y (npy) and agonists and antagonists thereof for tissue regeneration
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1998
- 1998-07-10 ID IDW20000021A patent/ID24300A/id unknown
- 1998-07-10 CN CN98807398A patent/CN1264381A/zh active Pending
- 1998-07-10 JP JP2000506207A patent/JP3711238B2/ja not_active Expired - Fee Related
- 1998-07-10 AT AT98929573T patent/ATE296825T1/de not_active IP Right Cessation
- 1998-07-10 EA EA200000098A patent/EA200000098A1/ru unknown
- 1998-07-10 HU HU0002956A patent/HUP0002956A3/hu unknown
- 1998-07-10 EP EP98929573A patent/EP1003744B1/en not_active Expired - Lifetime
- 1998-07-10 IL IL13343098A patent/IL133430A0/xx unknown
- 1998-07-10 US US09/380,901 patent/US6187778B1/en not_active Expired - Fee Related
- 1998-07-10 ES ES98929573T patent/ES2241146T3/es not_active Expired - Lifetime
- 1998-07-10 AU AU79274/98A patent/AU7927498A/en not_active Abandoned
- 1998-07-10 DE DE69830409T patent/DE69830409T2/de not_active Expired - Fee Related
- 1998-07-10 WO PCT/IB1998/001053 patent/WO1999007703A1/en not_active Ceased
- 1998-07-10 CA CA002293621A patent/CA2293621C/en not_active Expired - Fee Related
- 1998-07-10 PL PL98338575A patent/PL338575A1/xx unknown
- 1998-07-10 KR KR1020007001174A patent/KR20010022583A/ko not_active Ceased
- 1998-07-10 TR TR2000/00333T patent/TR200000333T2/xx unknown
- 1998-07-10 BR BR9811844-7A patent/BR9811844A/pt not_active Application Discontinuation
- 1998-07-27 GT GT199800114A patent/GT199800114A/es unknown
- 1998-07-30 PE PE1998000678A patent/PE106199A1/es not_active Application Discontinuation
- 1998-07-30 AP APAP/P/1998/001312A patent/AP9801312A0/en unknown
- 1998-08-03 PA PA19988456601A patent/PA8456601A1/es unknown
- 1998-08-04 ZA ZA9806968A patent/ZA986968B/xx unknown
- 1998-08-04 MA MA25203A patent/MA24629A1/fr unknown
- 1998-08-04 HR HR60/054,734A patent/HRP980434A2/hr not_active Application Discontinuation
- 1998-08-04 TN TNTNSN98148A patent/TNSN98148A1/fr unknown
- 1998-08-05 CO CO98044925A patent/CO4960634A1/es unknown
- 1998-08-19 SA SA98190435A patent/SA98190435A/ar unknown
1999
- 1999-12-10 IS IS5294A patent/IS5294A/is unknown
- 1999-12-14 NO NO996178A patent/NO996178L/no not_active Application Discontinuation
2000
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Also Published As

Publication number	Publication date
HUP0002956A3 (en)	2002-01-28
IL133430A0 (en)	2001-04-30
HRP980434A2 (en)	1999-04-30
EP1003744B1 (en)	2005-06-01
CA2293621A1 (en)	1999-02-18
AP9801312A0 (en)	2000-01-30
TR200000333T2 (tr)	2000-05-22
NO996178L (no)	2000-02-14
GT199800114A (es)	2000-01-18
DE69830409T2 (de)	2006-01-26
ID24300A (id)	2000-07-13
AU7927498A (en)	1999-03-01
US6187778B1 (en)	2001-02-13
ZA986968B (en)	2000-02-04
ATE296825T1 (de)	2005-06-15
EP1003744A1 (en)	2000-05-31
KR20010022583A (ko)	2001-03-26
CO4960634A1 (es)	2000-09-25
SA98190435A (ar)	2005-12-03
PE106199A1 (es)	1999-11-02
JP2001512729A (ja)	2001-08-28
PL338575A1 (en)	2000-11-06
JP3711238B2 (ja)	2005-11-02
TNSN98148A1 (fr)	2005-03-15
OA11277A (en)	2003-07-29
ES2241146T3 (es)	2005-10-16
NO996178D0 (no)	1999-12-14
MA24629A1 (fr)	1999-04-01
BR9811844A (pt)	2000-08-08
CN1264381A (zh)	2000-08-23
CA2293621C (en)	2003-12-30
WO1999007703A1 (en)	1999-02-18
EA200000098A1 (ru)	2000-08-28
PA8456601A1 (es)	2000-05-24
HUP0002956A2 (hu)	2001-08-28
DE69830409D1 (de)	2005-07-07
IS5294A (is)	1999-12-10

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BG104107A (bg)	2000-08-31	4-АМИНОПИРОЛ/3,2-d/ ПИРИМИДИНИ КАТО РЕЦЕПТОРНИ АНТАГОНИСТИ НА НЕВРОПЕПТИД Y
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EP1833830B1 (de)	2009-10-14	Chinolinderivat, dessen verwendung, herstellung und dieses enthaltendes arzneimittel
US6511984B2 (en)	2003-01-28	Neuropeptide Y antagonists
US6197822B1 (en)	2001-03-06	Neuropeptide antagonists
US6147085A (en)	2000-11-14	Aminoalkyl substituted 9H-pyridino[2,3-b] indole and 9H-pyrimidino[4,5-b] indole derivatives
EP1033366A2 (en)	2000-09-06	Amide derivatives useful as Neuropeptide Y (NPY) antagonists
US6649759B2 (en)	2003-11-18	Neuropeptide Y antagonists
MXPA99012095A (es)	2000-09-04	4-aminopirrol (3,2-d) pirimidinas como antagonistas del receptor del neuropeptido y
CZ439199A3 (cs)	2000-07-12	4-Aminopyrrol(3^-d)pyrimidiny jako antagonisty receptoru neuropeptidu Y
JP2006501244A5 (pt)	2006-08-31