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BE817878A - Nouveaux derives du benzamido-2 nitro-5 thiazole - Google Patents

Nouveaux derives du benzamido-2 nitro-5 thiazole

Info

Publication number
BE817878A
BE817878A BE146759A BE146759A BE817878A BE 817878 A BE817878 A BE 817878A BE 146759 A BE146759 A BE 146759A BE 146759 A BE146759 A BE 146759A BE 817878 A BE817878 A BE 817878A
Authority
BE
Belgium
Prior art keywords
benzamido
thiazole
nitro
new derivatives
derivatives
Prior art date
Application number
BE146759A
Other languages
English (en)
French (fr)
Inventor
J-F Rossignol
R Cavier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE817878A publication Critical patent/BE817878A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/58—Nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
BE146759A 1973-08-08 1974-07-19 Nouveaux derives du benzamido-2 nitro-5 thiazole BE817878A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3760873A GB1437800A (en) 1973-08-08 1973-08-08 Derivatives of 2-benzamido-5-nitro-thiazoles

Publications (1)

Publication Number Publication Date
BE817878A true BE817878A (fr) 1975-01-20

Family

ID=10397712

Family Applications (1)

Application Number Title Priority Date Filing Date
BE146759A BE817878A (fr) 1973-08-08 1974-07-19 Nouveaux derives du benzamido-2 nitro-5 thiazole

Country Status (14)

Country Link
US (1) US3950351A (de)
JP (1) JPS5041858A (de)
AR (1) AR201880A1 (de)
BE (1) BE817878A (de)
CA (1) CA1041519A (de)
CH (1) CH583215A5 (de)
DE (1) DE2438037C2 (de)
ES (1) ES428906A1 (de)
FR (1) FR2240010B1 (de)
GB (1) GB1437800A (de)
IL (1) IL45194A (de)
NL (1) NL176779C (de)
OA (1) OA04761A (de)
ZA (1) ZA744409B (de)

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FR2435905A1 (fr) * 1978-09-13 1980-04-11 Anvar Nouveaux agents molluscicides derives du benzamido-2 nitro-5 thiazole
US4315018A (en) * 1978-12-07 1982-02-09 Rossignol Jean F Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives
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US5387598A (en) * 1994-04-13 1995-02-07 Rossignol; Jean-Francois Composition and galenic formulation suitable for combatting affections of the lower abdomen
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JP2008542247A (ja) * 2005-05-24 2008-11-27 アストラゼネカ アクチボラグ グルコキナーゼモジュレーターとしての２−フェニル置換イミダゾール［４，５ｂ］ピリジン／ピラジンおよびプリン誘導体
TW200714597A (en) * 2005-05-27 2007-04-16 Astrazeneca Ab Chemical compounds
JP4651714B2 (ja) * 2005-07-09 2011-03-16 アストラゼネカ アクチボラグ 糖尿病の治療においてｇｌｋ活性化剤として使用するためのヘテロアリールベンズアミド誘導体
EP2027113A1 (de) * 2005-07-09 2009-02-25 AstraZeneca AB Heteroarylbenzamidderivate zur verwendung als glk-aktivatoren bei der behandlung von diabetes
EP1910350A1 (de) * 2005-07-09 2008-04-16 AstraZeneca AB 2-heterocyclyloxybenzoylaminoheterocyclyl-verbindungen als modulatoren der glucokinase zur behandlung von typ-2-diabetes
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TW200738621A (en) * 2005-11-28 2007-10-16 Astrazeneca Ab Chemical process
ES2422556T3 (es) 2006-01-09 2013-09-12 Romark Lab Lc Tratamiento de hepatitis vírica
US7678791B2 (en) * 2006-07-12 2010-03-16 Cumbre Ip Ventures, L.P. Nitroheteroaryl-containing rifamycin derivatives
CN100465169C (zh) * 2006-08-02 2009-03-04 杭州欣阳三友精细化工有限公司 硝唑尼特的制备方法
TW200825063A (en) * 2006-10-23 2008-06-16 Astrazeneca Ab Chemical compounds
CL2007003061A1 (es) * 2006-10-26 2008-08-01 Astrazeneca Ab Compuestos derivados de 3,5-dioxi-benzamida; proceso de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar una enfermedad mediada a traves de glk, tal como la diabetes tipo 2.
US20100094009A1 (en) * 2006-12-21 2010-04-15 Mccabe James Novel crystalline compound useful as glk activator
CN101007792B (zh) * 2007-01-31 2010-05-26 浙江大学 一种合成硝基噻唑苯酰胺化合物的方法
ES2550755T3 (es) * 2007-08-03 2015-11-12 Romark Laboratories, L.C. Compuestos de tiazolida sustituidos con alquilsulfonilo
EP2324028A2 (de) * 2008-08-04 2011-05-25 AstraZeneca AB Therapeutische mittel 414
TW201639852A (zh) 2008-12-09 2016-11-16 吉李德科學股份有限公司 用於製備可用作類鐸受體調節劑之化合物的中間體化合物
GB0902406D0 (en) * 2009-02-13 2009-04-01 Astrazeneca Ab Crystalline polymorphic form
JP5726766B2 (ja) 2009-02-13 2015-06-03 ロマーク ラボラトリーズ エル．シー． ニタゾキサニドの制御放出医薬配合物
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WO2010116176A1 (en) * 2009-04-09 2010-10-14 Astrazeneca Ab Pyrazolo [4, 5-e] pyrimidine derivative and its use to treat diabetes and obesity
WO2010116177A1 (en) 2009-04-09 2010-10-14 Astrazeneca Ab A pyrazolo [4,5-e] pyrimidine derivative and its use to treat diabetes and obesity
KR101760956B1 (ko) * 2009-05-12 2017-07-24 로마크 레버러토리즈, 엘.씨. 할로알킬 헤테로아릴 벤즈아미드 화합물
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CN101602744B (zh) * 2009-06-30 2011-06-01 青岛康地恩药业有限公司 一种硝唑尼特的制备方法
EP2808019B1 (de) 2012-01-27 2019-09-25 Siegfried Rhein S.A. De C.V. Verbesserte nitazoxanidzusammensetzung und herstellungsverfahren dafür
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US20160244435A1 (en) * 2013-06-21 2016-08-25 The Scripps Research Institute Expanded therapeutic potential in nitroheteroaryl antimicrobials
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JP6633092B2 (ja) 2014-11-11 2020-01-22 ロマーク ラボラトリーズ，リミティド カンパニー チゾキサニド、その類似体又は塩のプロドラッグを用いる組成物及び治療方法
CN105175352A (zh) * 2015-10-27 2015-12-23 杭州澳医保灵药业有限公司 一种硝唑尼特的制备方法
CN106831640A (zh) * 2015-12-03 2017-06-13 江苏正大丰海制药有限公司 一种硝唑尼特晶体的制备方法
CN108289961A (zh) 2016-03-31 2018-07-17 罗马克实验室有限公司 用于治疗病毒性感染的噻唑化物化合物
DK3442580T3 (da) 2016-04-11 2020-12-21 Genfit Fremgangsmåder til behandling af kolestatiske og fibrotiske sygdomme
AU2018212614B2 (en) 2017-01-27 2024-02-01 Genfit Pharmaceutical compositions for combination therapy
WO2018195035A1 (en) 2017-04-18 2018-10-25 Romark Laboratories L.C. Inhibition of protein disulfide-isomerase a3
WO2019241376A1 (en) 2018-06-14 2019-12-19 The Trustees Of Columbia University In The City Of New York Treatment of cognitive disorders using nitazoxanide (ntz), nitazoxanide (ntz) analogs, and metabolites thereof
EP3952869A1 (de) 2019-04-12 2022-02-16 Genfit Nitazoxanid und thiazolide zur verwendung bei der behandlung von krankheiten in zusammenhang mit oxidativem stress
WO2021083912A1 (en) 2019-10-28 2021-05-06 Genfit Combination therapy having antioxydant properties
JP2023537237A (ja) 2020-07-20 2023-08-31 ロマーク ラボラトリーズ，リミティド カンパニー チゾキサニドおよび２－ヒドロキシ－ｎ－（５－クロロ－１，３－チアゾル－２－イル）ベンズアミド（ｒｍ－４８４８）とエタノールアミン、モルホリン、プロパノールアミン、ピペラジン、およびｎ－メチルピペラジンの結晶塩
CN116367892A (zh) 2020-08-24 2023-06-30 罗马克实验室有限公司 噻唑化物抗冠状病毒的用途
CN114044761B (zh) * 2021-02-24 2022-05-17 成都贝诺科成生物科技有限公司 一种新的硝基噻唑衍生物及其应用
CN115197164B (zh) * 2021-04-12 2025-04-01 杜心赟 新型噻唑类化合物及其制备方法和用途
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Also Published As

Publication number Publication date
FR2240010A1 (de) 1975-03-07
AU7135574A (en) 1976-01-22
DE2438037C2 (de) 1982-06-09
NL176779B (nl) 1985-01-02
JPS5041858A (de) 1975-04-16
OA04761A (fr) 1980-08-31
FR2240010B1 (de) 1978-03-24
AR201880A1 (es) 1975-04-24
NL7409321A (nl) 1975-02-11
CA1041519A (en) 1978-10-31
US3950351A (en) 1976-04-13
IL45194A (en) 1977-10-31
IL45194A0 (en) 1974-10-22
ES428906A1 (es) 1976-08-16
NL176779C (nl) 1985-06-03
ZA744409B (en) 1975-07-30
GB1437800A (en) 1976-06-03
CH583215A5 (de) 1976-12-31
DE2438037A1 (de) 1975-02-20

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: ROSSIGNOL JEAN-FRANCOIS

Effective date: 19850731