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BE578515A - - Google Patents

Info

Publication number
BE578515A
BE578515A BE578515DA BE578515A BE 578515 A BE578515 A BE 578515A BE 578515D A BE578515D A BE 578515DA BE 578515 A BE578515 A BE 578515A
Authority
BE
Belgium
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication of BE578515A publication Critical patent/BE578515A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BE578515D 1958-05-07 BE578515A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF25702A DE1111642B (de) 1958-05-07 1958-05-07 Verfahren zur Herstellung von basisch substituierten Diphenylmethan-Derivaten mit Herz- und Kreislaufwirksamkeit

Publications (1)

Publication Number Publication Date
BE578515A true BE578515A (da)

Family

ID=7091732

Family Applications (1)

Application Number Title Priority Date Filing Date
BE578515D BE578515A (da) 1958-05-07

Country Status (10)

Country Link
US (1) US3152173A (da)
BE (1) BE578515A (da)
CH (8) CH388334A (da)
CY (1) CY277A (da)
DE (1) DE1111642B (da)
FR (1) FR553M (da)
GB (1) GB916644A (da)
MY (1) MY6400049A (da)
NL (2) NL108640C (da)
OA (1) OA01363A (da)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
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US3262977A (en) * 1962-03-10 1966-07-26 Chinoin Gyogyszer Es Vegyeszet N-aralkyl-1, 1-diphenyl-propylamine derivatives
NL296693A (da) * 1962-08-16
DK111894A (da) 1962-11-15
FR95908E (fr) * 1963-11-09 1972-01-31 Degussa Procédé de préparation de nouvelles aminocétones et des alcools secondaires correspondants.
DE1231704B (de) 1963-12-19 1967-01-05 Josef Klosa Dipl Chem Dr Rer N Verfahren zur Herstellung neuer Diaryl-alkylaminoverbindungen mit heterocyclischen Ringen
US3457354A (en) * 1965-09-21 1969-07-22 Merck & Co Inc Treatment of hypertension with 2-hydroxy (or amino) - 4,5 - dihydroxyphenethylamine derivatives
US3895057A (en) * 1967-10-13 1975-07-15 Dainippon Pharmaceutical Co Aminoalkanols and their pharmaceutically acceptable acid-addition salts, and production thereof
US4329367A (en) * 1974-08-05 1982-05-11 Ciba-Geigy Corporation 1-(Aralkoxyphenyl)-2-(bis-arylalkylamino)-alkanes
DE2902172C2 (de) * 1979-01-20 1984-05-10 UOP Inc., 60016 Des Plaines, Ill. Verfahren zur Herstellung eines N,N'-Dialkylphenylendiamins
EP0105872B1 (en) * 1982-04-23 1988-03-30 Caola Kozmetikai Es Haztartäsvegyipari Vallalat Novel cosmetic compositions containing prenylamine and a process for their preparation
DE3662521D1 (de) * 1985-04-16 1989-04-27 Hoffmann La Roche Phenethanol amine derivatives
US6982251B2 (en) * 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
JP2004517916A (ja) * 2001-01-26 2004-06-17 シェーリング　コーポレイション ニコチン酸およびその誘導体ならびにステロール吸収阻害剤の併用、および血管適応症の治療
JP2004517919A (ja) * 2001-01-26 2004-06-17 シェーリング　コーポレイション 血管状態の処置のための心臓血管薬剤とステロール吸収インヒビターとの組み合わせ
ME00145B (me) * 2001-01-26 2010-10-10 Merck Sharp & Dohme Upotreba supstituisanih jedinjenja azetidinona za lečenje sitosterolemije
ES2287250T3 (es) * 2001-01-26 2007-12-16 Schering Corporation Combinaciones de secuestrante(s) de acidos biliares e inhibidor(es) de la absorcion de esteroles y tratamientos para indicaciones vasculares.
US7071181B2 (en) * 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
IL156445A0 (en) * 2001-01-26 2004-01-04 Schering Corp Combinations of peroxisome proliferator-activated receptor (ppar) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications
KR20080067717A (ko) * 2001-01-26 2008-07-21 쉐링 코포레이션 스테롤 흡수 억제제와 혈액 조절제를 포함하는 혈관 질환의치료 또는 예방용 약제학적 조성물
PT1392287E (pt) * 2001-05-25 2007-02-28 Schering Corp Métodos para tratamento de doença de alzheimer e/ou regulação dos níveis de peptídeos β amilóide num sujeito
ES2272776T3 (es) * 2001-09-21 2007-05-01 Schering Corporation Tratamiento de xantomas con derivados de azetidinona como inhibidores de la absorcion de esterol.
US7053080B2 (en) * 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US7056906B2 (en) * 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
US20030119808A1 (en) * 2001-09-21 2003-06-26 Schering Corporation Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects
AU2002335770B2 (en) * 2001-09-21 2005-08-18 Merck Sharp & Dohme Corp. Methods for treating or preventing vascular inflammation using sterol absorption inhibitor(s)
BR0313593A (pt) 2002-08-19 2005-07-12 Pfizer Prod Inc Terapia de combinação para doenças hiperproliferativas
WO2004043457A1 (en) * 2002-11-06 2004-05-27 Schering Corporation Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
DE602004018617D1 (de) 2003-03-07 2009-02-05 Schering Corp Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
US7192944B2 (en) * 2003-03-07 2007-03-20 Schering Corp. Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
DE602004016123D1 (de) 2003-03-07 2008-10-09 Schering Corp Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
EP1680189A2 (en) * 2003-11-05 2006-07-19 Schering Corporation Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions
CA2574958A1 (en) * 2004-07-26 2006-02-09 Cotherix, Inc. Treatment of pulmonary hypertension by inhaled iloprost with a microparticle formulation
US20060063803A1 (en) * 2004-09-23 2006-03-23 Pfizer Inc 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
EP1951253A2 (en) * 2005-10-26 2008-08-06 Cotherix, Inc. Fasudil in combination therapies for the treatment of pulmonary arterial hypertension
EP2351569B1 (en) 2005-10-26 2012-08-22 Asahi Kasei Pharma Corporation Fasudil in combination therapies for the treatment of pulmonary arterial hypertension
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
CN101663262B (zh) 2006-12-01 2014-03-26 百时美施贵宝公司 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物
US7879802B2 (en) 2007-06-04 2011-02-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
AU2009256157B2 (en) 2008-06-04 2014-12-18 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
JP2011528375A (ja) 2008-07-16 2011-11-17 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
WO2012037665A1 (en) 2010-09-24 2012-03-29 Oral Delivery Technology Ltd. Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
JP2016514671A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
JP2016516804A (ja) 2013-04-17 2016-06-09 ファイザー・インク 心血管疾患を治療するためのｎ−ピペリジン−３−イルベンズアミド誘導体
AU2014274812B2 (en) 2013-06-05 2018-09-27 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase C, method of making and using same
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
AU2020209215B2 (en) 2019-01-18 2023-02-02 Astrazeneca Ab PCSK9 inhibitors and methods of use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2601323A (en) * 1949-02-02 1952-06-24 Upjohn Co Process for preparing 4, 4-diphenyl-6-dimethylamino-heptanone-3
US2681934A (en) * 1950-01-06 1954-06-22 Commercial Solvents Corp Substituted diphenylalkylamines
US2797242A (en) * 1953-08-11 1957-06-25 Parke Davis & Co Substituted alpha-benzylphenethylamines and methods for producing the same
US2738347A (en) * 1954-12-13 1956-03-13 Olin Mathieson Penicillin salt of benzhydryl-phenethylamine
US2872374A (en) * 1955-02-02 1959-02-03 Nat Drug Co Muscle-relaxing tranquilizer compositions
US2894033A (en) * 1955-11-15 1959-07-07 Nl Combinatie Chem Ind Antispasmodic 1, 1-diphenyl-3-dialkylaminopropane, and its tertiary and quaternary salts
US2854379A (en) * 1956-06-06 1958-09-30 Miles Lab Tranquilizing composition comprising 2-ethyl-cis-crotonylurea
DE1058063B (de) * 1957-02-08 1959-05-27 Hoechst Ag Verfahren zur Herstellung von analgetisch wirksamen substituierten Phenylaethylaminen

Also Published As

Publication number Publication date
DE1111642B (de) 1961-07-27
CH388329A (de) 1965-02-28
CH385878A (de) 1964-12-31
CH388334A (de) 1965-02-28
CH388332A (de) 1965-02-28
NL238796A (da)
FR553M (da) 1961-05-29
OA01363A (fr) 1969-07-04
MY6400049A (en) 1964-12-31
CH388333A (de) 1965-02-28
CH397710A (de) 1965-08-31
NL108640C (da)
CY277A (en) 1964-02-12
US3152173A (en) 1964-10-06
GB916644A (en) 1963-01-23
CH396931A (de) 1965-08-15
CH388328A (de) 1965-02-28

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