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BE2015C015I2 - - Google Patents

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Publication number
BE2015C015I2
BE2015C015I2 BE2015C015C BE2015C015C BE2015C015I2 BE 2015C015 I2 BE2015C015 I2 BE 2015C015I2 BE 2015C015 C BE2015C015 C BE 2015C015C BE 2015C015 C BE2015C015 C BE 2015C015C BE 2015C015 I2 BE2015C015 I2 BE 2015C015I2
Authority
BE
Belgium
Application number
BE2015C015C
Other languages
Dutch (nl)
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Publication of BE2015C015I2 publication Critical patent/BE2015C015I2/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C15/00—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts
    • C07C15/02—Monocyclic hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/11—Aldehydes
    • A61K31/115—Formaldehyde
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/001—Acyclic or carbocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/78—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C217/80—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BE2015C015C 2004-12-17 2015-03-10 BE2015C015I2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63669604P 2004-12-17 2004-12-17
US68639505P 2005-06-02 2005-06-02
EP05854410A EP1841465A4 (fr) 2004-12-17 2005-12-19 Derives de stilbene et leur utilisation pour la liaison et l'imagerie de plaques amyloides

Publications (1)

Publication Number Publication Date
BE2015C015I2 true BE2015C015I2 (fr) 2025-04-29

Family

ID=36588603

Family Applications (1)

Application Number Title Priority Date Filing Date
BE2015C015C BE2015C015I2 (fr) 2004-12-17 2015-03-10

Country Status (25)

Country Link
US (2) US7807135B2 (fr)
EP (3) EP1841465A4 (fr)
JP (1) JP5128956B2 (fr)
KR (1) KR101321619B1 (fr)
AU (1) AU2005316421B2 (fr)
BE (1) BE2015C015I2 (fr)
BR (1) BRPI0516408B8 (fr)
CA (1) CA2591534C (fr)
DK (1) DK2213652T3 (fr)
EA (1) EA012334B1 (fr)
ES (1) ES2526655T3 (fr)
FR (1) FR15C0012I2 (fr)
HU (1) HUS1500014I1 (fr)
IL (2) IL183946A (fr)
LT (1) LTC2213652I2 (fr)
LU (1) LU92647I2 (fr)
MX (1) MX2007007380A (fr)
NL (1) NL300719I2 (fr)
NO (1) NO339195B1 (fr)
NZ (1) NZ555942A (fr)
PL (1) PL2213652T3 (fr)
PT (1) PT2213652E (fr)
SG (1) SG194363A1 (fr)
SI (1) SI2213652T1 (fr)
WO (1) WO2006066104A2 (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101003526B (zh) * 2001-08-27 2012-02-22 宾夕法尼亚州大学理事会 茋衍生物及其用于结合和成像淀粉样蛋白斑的用途
SI2213652T1 (sl) * 2004-12-17 2015-03-31 The Trustees Of The University Of Pennsylvania Derivati stilbena in njihova uporaba za vezavo in prikaz amiloidnih plakov
US7858072B2 (en) * 2004-12-17 2010-12-28 The Trustees Of The University Of Pennsylvania Stilbene derivatives and their use for binding and imaging amyloid plaques
JP2008546804A (ja) * 2005-06-24 2008-12-25 ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア 造影剤として用いるためのリガンドの放射性標識ペグ化
JP5290954B2 (ja) * 2006-03-30 2013-09-18 ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア スチリルピリジン誘導体及びアミロイド斑を結合させ画像化するためのその使用
US20080253967A1 (en) * 2007-04-13 2008-10-16 Kung Hank F Halo-Stilbene Derivatives And Their Use For Binding And Imaging Of Amyloid Plaques
WO2009001046A2 (fr) * 2007-06-22 2008-12-31 The University Court Of The University Of Aberdeen 2,3',4,5'-tétraméthylstilbène (tms) radiomarqué par [11c]méthoxy et ses préparation et utilisation
WO2009004914A1 (fr) * 2007-07-04 2009-01-08 Tohoku University Sonde de tep ayant un groupe alcoxy substitué par un atome de fluor et un groupe hydroxy
ES2447940T3 (es) * 2007-10-15 2014-03-13 The Salk Institute For Biological Studies Métodos para el tratamiento de varias enfermedades y afecciones, y compuestos útiles para los mismos
US8932557B2 (en) 2008-02-14 2015-01-13 Eli Lilly And Company Imaging agents for detecting neurological dysfunction
HUE058352T2 (hu) * 2008-02-14 2022-07-28 Lilly Co Eli Új képalkotó szerek neurológiai diszfunkció kimutatására
AU2009219406A1 (en) * 2008-02-27 2009-09-03 Avid Radiopharmaceuticals, Inc. Gamma probe detection of amyloid plaque using radiolabeled A-beta binding compounds
US8557222B2 (en) * 2008-04-04 2013-10-15 Avid Radiopharmaceuticals, Inc. Radiopharmaceutical imaging of neurodegenerative diseases
US20100145194A1 (en) * 2008-11-13 2010-06-10 Avid Radiopharmaceuticals, Inc. Histogram-based analysis method for the detection and diagnosis of neurodegenerative diseases
US20110305618A1 (en) 2008-12-22 2011-12-15 Bayer Schering Pharma Aktiengesellschaft Method for synthesis of a radionuclide-labeled compound using an exchange resin
CN102271716B (zh) * 2008-12-31 2014-11-19 阿维德放射性药品公司 由甲苯磺酸酯前体合成18f-放射性标记的苯乙烯基吡啶及其稳定的药物组合物
CU23844B1 (es) 2009-04-17 2012-10-15 Ct De Neurociencias De Cuba Procedimiento de obtención de nuevos derivados de naftaleno para el diagnóstico in vivo de la enfermedad de alzheimer
CN102471177A (zh) * 2009-07-10 2012-05-23 拜耳医药股份有限公司 低至中压液相色谱在放射性示踪剂纯化中的应用
SG181903A1 (en) * 2009-12-23 2012-07-30 Piramal Imaging Sa Formulations suitable for pet imaging with hydrophobic pet agents
US20140012032A1 (en) 2010-06-04 2014-01-09 Piramal Imaging Sa Method for production of f-18 labeled amyloid beta ligands
BR112012030946A2 (pt) * 2010-06-04 2016-11-01 Piramal Imaging Sa método para a produção de ligante para amiloide beta marcado com f-18
HRP20171397T4 (hr) 2010-06-04 2019-11-15 Life Molecular Imaging Sa Postupak proizvodnje liganada amiloida beta obilježenih s f-18
TWI504414B (zh) 2010-06-04 2015-10-21 Bayer Schering Pharma Ag 生產Ｆ－１８標記之Ａβ配位體之方法
WO2012051170A2 (fr) * 2010-10-12 2012-04-19 Mayo Foundation For Medical Education And Research Imagerie de méningiomes en utilisant des dérivés de phingylbenzothiazole, stilbène, ou biphénylalcyne
CN106729771A (zh) * 2011-04-21 2017-05-31 加利福尼亚大学董事会 官能化磁性纳米颗粒及在淀粉样沉积物和神经原纤维缠结成像中用途
BR112013032610B1 (pt) 2011-06-21 2022-05-31 Life Molecular Imaging Sa Formulações de estilbeno fluorado adequadas para imagiologia pet, e seus métodos de preparação, obtenção e filtração estéril
KR101291037B1 (ko) * 2011-10-12 2013-08-01 사회복지법인 삼성생명공익재단 레스베라트롤 유도체와 스티릴-오각형 방향족 화합물 및 이들의 베타-아밀로이드 플라그에 대한 결합제 및 진단영상제의 용도
RU2477726C1 (ru) * 2011-10-18 2013-03-20 Общество С Ограниченной Ответственностью "Ньювак" (Ооо "Ньювак") Замещенные феноксиуксусные кислоты, их эфиры и амиды, включающие 2,6-диоксо-2,3,6,7-тетрагидро-1н-пурин-8-иловый фрагмент, - антагонисты аденозинового a2a рецептора и их применение
SG11201401640QA (en) 2011-10-19 2014-07-30 Piramal Imaging Sa IMPROVED METHOD FOR PRODUCTION OF F-18 LABELED Aß LIGANDS
BR112014024997B1 (pt) 2012-04-10 2021-03-09 Lantheus Medical Imaging, Inc. métodos de síntese radiofarmacêutica
US9180212B2 (en) * 2012-05-22 2015-11-10 The Regents Of The University Of California β-amyloid plaque imaging agents
CU20130027A7 (es) 2013-02-28 2014-10-30 Ct De Neurociencias De Cuba Chaperoninas químicas como nuevos moduladores moleculares de la beta agregación proteica presente en las enfermedades conformacionales
JP6041751B2 (ja) * 2013-05-07 2016-12-14 日本メジフィジックス株式会社 スチリルピリジン誘導体化合物
JP2014218454A (ja) * 2013-05-07 2014-11-20 日本メジフィジックス株式会社 スチリルピリジン誘導体化合物
KR101891404B1 (ko) 2015-12-18 2018-08-24 주식회사 엘지화학 변성 단량체, 이를 포함하는 변성 중합체 및 이들의 제조방법
CN109790184B (zh) 2016-09-29 2021-06-29 韩国原子力研究院 姜黄素衍生物、其制备方法、以及用于检测β-淀粉样蛋白斑的包含该姜黄素衍生物的光声成像剂
JOP20190077A1 (ar) 2016-10-10 2019-04-09 Array Biopharma Inc مركبات بيرازولو [1، 5-a]بيريدين بها استبدال كمثبطات كيناز ret

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US4500507A (en) * 1981-10-30 1985-02-19 Wong Dennis W Diagnostic composition for radiologic imaging of neoplasms in the body and method of preparation
JPS60247244A (ja) 1984-05-22 1985-12-06 Mitsubishi Paper Mills Ltd 電子写真感光体
DD234666A1 (de) 1984-11-01 1986-04-09 Univ Leipzig Verfahren zur herstellung von einfachen und substituierten 4-dimethylamino-alpha-halogenstilbenen
DD231432A1 (de) 1984-11-01 1985-12-24 Univ Leipzig Material zur silberfreien bildaufzeichnung
JPH06329566A (ja) 1993-05-21 1994-11-29 Asahi Glass Co Ltd ジフルオロスチルベン誘導体化合物およびそれを含有する液晶組成物
TW325458B (en) 1993-09-08 1998-01-21 Ajinomoto Kk Stilbene derivatives and pharmaceutical compositions comprising the same for anti-cancer
US5601801A (en) 1994-08-02 1997-02-11 Merck Frosst Canada, Inc. Radiolabelled angiotensin converting enzyme inhibitors
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JP4022951B2 (ja) 1997-08-06 2007-12-19 大日本インキ化学工業株式会社 ジフルオロスチルベン誘導体の製造方法
AU5822301A (en) * 2000-05-08 2001-11-20 Novozymes A/S Oxidoreductase mediated antimicrobial activity
CN101003526B (zh) * 2001-08-27 2012-02-22 宾夕法尼亚州大学理事会 茋衍生物及其用于结合和成像淀粉样蛋白斑的用途
KR100789847B1 (ko) * 2004-12-15 2007-12-28 (주)퓨쳐켐 알코올 용매하에서 유기플루오로 화합물의 제조방법
SI2213652T1 (sl) * 2004-12-17 2015-03-31 The Trustees Of The University Of Pennsylvania Derivati stilbena in njihova uporaba za vezavo in prikaz amiloidnih plakov
US7858072B2 (en) 2004-12-17 2010-12-28 The Trustees Of The University Of Pennsylvania Stilbene derivatives and their use for binding and imaging amyloid plaques
JP2008546804A (ja) * 2005-06-24 2008-12-25 ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア 造影剤として用いるためのリガンドの放射性標識ペグ化

Also Published As

Publication number Publication date
IL183946A0 (en) 2007-10-31
IL206091A (en) 2013-08-29
BRPI0516408A (pt) 2008-09-02
NO339195B1 (no) 2016-11-14
EP1841465A2 (fr) 2007-10-10
SG194363A1 (en) 2013-11-29
IL183946A (en) 2011-08-31
EP1838298A4 (fr) 2009-03-04
CA2591534A1 (fr) 2006-06-22
NZ555942A (en) 2011-01-28
US20060269473A1 (en) 2006-11-30
JP2008524243A (ja) 2008-07-10
FR15C0012I1 (fr) 2015-03-20
HUS1500014I1 (hu) 2016-11-28
US7807135B2 (en) 2010-10-05
KR101321619B1 (ko) 2013-10-30
LU92647I2 (fr) 2015-11-03
ES2526655T3 (es) 2015-01-14
AU2005316421B2 (en) 2012-04-05
WO2006066104A3 (fr) 2006-08-03
MX2007007380A (es) 2007-10-11
NO20073650L (no) 2007-09-14
EP1838298A2 (fr) 2007-10-03
NL300719I1 (fr) 2015-12-29
NL300719I2 (fr) 2015-12-29
US20100266500A1 (en) 2010-10-21
JP5128956B2 (ja) 2013-01-23
SI2213652T1 (sl) 2015-03-31
BRPI0516408B8 (pt) 2021-05-25
KR20070093427A (ko) 2007-09-18
FR15C0012I2 (fr) 2015-11-20
WO2006066104A2 (fr) 2006-06-22
EA200701299A1 (ru) 2007-12-28
CA2591534C (fr) 2013-08-06
DK2213652T3 (en) 2015-01-26
US8465726B2 (en) 2013-06-18
PT2213652E (pt) 2015-01-02
EP2213652B1 (fr) 2014-10-22
EP2213652A1 (fr) 2010-08-04
LTC2213652I2 (lt) 2016-12-27
BRPI0516408B1 (pt) 2021-03-23
EA012334B1 (ru) 2009-08-28
AU2005316421A1 (en) 2006-06-22
EP1841465A4 (fr) 2009-04-01
PL2213652T3 (pl) 2015-04-30

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