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AU9646198A - Isoquinoline derivative and drug - Google Patents

Isoquinoline derivative and drug

Info

Publication number
AU9646198A
AU9646198A AU96461/98A AU9646198A AU9646198A AU 9646198 A AU9646198 A AU 9646198A AU 96461/98 A AU96461/98 A AU 96461/98A AU 9646198 A AU9646198 A AU 9646198A AU 9646198 A AU9646198 A AU 9646198A
Authority
AU
Australia
Prior art keywords
drug
isoquinoline derivative
isoquinoline
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU96461/98A
Inventor
Hiroyoshi Hidaka
Akira Matsuura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shinyaku Co Ltd
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Publication of AU9646198A publication Critical patent/AU9646198A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU96461/98A 1997-10-22 1998-10-22 Isoquinoline derivative and drug Abandoned AU9646198A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP28968897 1997-10-22
JP9-289688 1997-10-22
PCT/JP1998/004781 WO1999020620A1 (en) 1997-10-22 1998-10-22 Isoquinoline derivative and drug

Publications (1)

Publication Number Publication Date
AU9646198A true AU9646198A (en) 1999-05-10

Family

ID=17746466

Family Applications (1)

Application Number Title Priority Date Filing Date
AU96461/98A Abandoned AU9646198A (en) 1997-10-22 1998-10-22 Isoquinoline derivative and drug

Country Status (3)

Country Link
JP (1) JP4316794B2 (en)
AU (1) AU9646198A (en)
WO (1) WO1999020620A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11633404B2 (en) 2007-08-29 2023-04-25 Senju Pharmaceutical Co., Ltd. Agent for promoting corneal endothelial cell adhesion

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7094789B2 (en) 2002-07-22 2006-08-22 Asahi Kasei Pharma Corporation 5-substituted isoquinoline derivatives
US7160894B2 (en) 2003-06-06 2007-01-09 Asahi Kasei Pharma Corporation Tricyclic compound
MY139797A (en) 2004-11-29 2009-10-30 Kowa Co (s)-(-)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1, 4-homopiperazine hydrochloride dihydrate
US7872136B2 (en) 2005-02-25 2011-01-18 Kowa Co., Ltd. Process for production of 4-fluoroisoquinoline-5-sulfonyl halide or salt thereof
WO2006115244A1 (en) * 2005-04-25 2006-11-02 D. Western Therapeutics Institute, Inc. 4-bromoisoquinoline derivative and pharmaceutical preparation comprising the same
WO2006115245A1 (en) * 2005-04-25 2006-11-02 D. Western Therapeutics Institute, Inc. 4-ethynylisoquinoline derivative and pharmaceutical preparation comprising the same
WO2006115247A1 (en) * 2005-04-25 2006-11-02 D. Western Therapeutics Institute, Inc. HIGHLY SELECTIVE Rho-KINASE INHIBITOR
CN101198354B (en) 2005-06-21 2012-01-11 兴和株式会社 Preventive or remedy for glaucoma
CN101198355B (en) 2005-07-12 2010-11-10 兴和株式会社 Drugs to prevent or treat glaucoma
RU2376300C1 (en) 2005-08-30 2009-12-20 Асахи Касеи Фарма Корпорэйшн Sulfonamide compound
JP4800720B2 (en) * 2005-09-21 2011-10-26 興和株式会社 Ophthalmic composition
WO2008105058A1 (en) 2007-02-27 2008-09-04 Asahi Kasei Pharma Corporation Sulfonamides
US7964613B2 (en) 2007-02-28 2011-06-21 Asahi Kasei Pharma Corporation Sulfonamide compound
WO2009004792A1 (en) 2007-07-02 2009-01-08 Asahi Kasei Pharma Corporation Sulfonamide compound, and crystal thereof
WO2012026529A1 (en) 2010-08-26 2012-03-01 興和株式会社 Novel production method for isoquinoline derivatives and salts thereof
EP2671586B1 (en) 2011-02-04 2018-05-30 Kowa Co., Ltd. Drug therapy for preventing or treating glaucoma
PT2788472T (en) 2011-12-06 2019-04-01 Astellas Inst For Regenerative Medicine DIRECTIVE DIFFERENTIATION METHOD FOR THE PRODUCTION OF CORNE ENDTHELIAL CELLS
EP3553169B1 (en) 2011-12-28 2021-11-03 Kyoto Prefectural Public University Corporation Normalization of culture of corneal endothelial cells
EP3626245B1 (en) 2013-04-24 2021-05-05 Kyushu University, National University Corporation Therapeutic agent for eyeground disease
WO2015016371A1 (en) 2013-07-30 2015-02-05 京都府公立大学法人 Corneal endothelial cell marker
RU2712967C2 (en) 2013-10-31 2020-02-03 Киото Прифекчурал Паблик Юниверсити Корпорэйшн Therapeutic drug for diseases related to endoplasmic reticulum cell death in corneal endothelium
JP6704721B2 (en) * 2014-12-12 2020-06-03 興和株式会社 Aqueous composition
PL3416658T3 (en) 2016-02-15 2023-09-04 Kyoto Prefectural Public University Corporation Human functional corneal endothelial cell and application thereof
CN107216311B (en) * 2016-03-21 2019-09-03 山东诚创医药技术开发有限公司 (s) -4- [(4- fluoro isoquinolin -5- base) sulfonyl] -3- methyl-1, the refining methd of 4- Diazesuberane hydrochloride
CN106496189A (en) * 2016-10-10 2017-03-15 江苏礼华生物技术有限公司 Hydrochloric acid Ripasudil crystal formations
JP7416700B2 (en) 2017-11-14 2024-01-17 ザ スキーペンズ アイ リサーチ インスティチュート インコーポレイテッド Methods of RUNX1 inhibition for the treatment of conditions associated with proliferative vitreoretinopathy and epithelial-mesenchymal transition
WO2020047229A1 (en) 2018-08-29 2020-03-05 University Of Massachusetts Inhibition of protein kinases to treat friedreich ataxia
CN113056556A (en) 2018-08-31 2021-06-29 学校法人同志社 Compositions and methods for preserving or culturing ocular cells
CA3109705A1 (en) 2018-10-02 2020-04-09 The Doshisha Method and vessel for preserving corneal endothelial cells
CN111116555B (en) 2018-10-30 2023-06-02 北京盈科瑞创新药物研究有限公司 A kind of Rho kinase inhibitor and its preparation method and application
BR112022017180A2 (en) 2020-02-27 2022-10-18 Kyoto Prefectural Public Univ Corp FUNCTIONAL HUMAN CORNEAL ENDOTHELIAL CELLS AND THEIR APPLICATION
CN111909088B (en) * 2020-08-04 2022-03-01 浙江工业大学 Method for preparing isoquinoline hydrochloride intermediate and Rho kinase inhibitor using BTC/Ph3PO chlorination system
BR112023021993A2 (en) 2021-05-03 2024-02-20 Astellas Inst For Regenerative Medicine METHODS FOR GENERATING ENDOTHELIAL CELLS FROM THE MATURE CORNEA
JPWO2023085369A1 (en) 2021-11-11 2023-05-19

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2205166T3 (en) * 1996-02-02 2004-05-01 D. Western Therapeutics Institute DERIVATIVES OF ISOQUINOLINE AND MEDICINAL PRODUCT.

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11633404B2 (en) 2007-08-29 2023-04-25 Senju Pharmaceutical Co., Ltd. Agent for promoting corneal endothelial cell adhesion
US11839618B2 (en) 2007-08-29 2023-12-12 Senju Pharmaceutical Co., Ltd. Agent for promoting corneal endothelial cell adhesion

Also Published As

Publication number Publication date
WO1999020620A1 (en) 1999-04-29
JP4316794B2 (en) 2009-08-19

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase