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AU1415099A - 4-substituted-4-piperidine carboxamide derivatives - Google Patents

4-substituted-4-piperidine carboxamide derivatives

Info

Publication number
AU1415099A
AU1415099A AU14150/99A AU1415099A AU1415099A AU 1415099 A AU1415099 A AU 1415099A AU 14150/99 A AU14150/99 A AU 14150/99A AU 1415099 A AU1415099 A AU 1415099A AU 1415099 A AU1415099 A AU 1415099A
Authority
AU
Australia
Prior art keywords
substituted
carboxamide derivatives
piperidine carboxamide
piperidine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU14150/99A
Inventor
William K. Hagmann
Stephen E. De Laszlo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9727214.0A external-priority patent/GB9727214D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU1415099A publication Critical patent/AU1415099A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/64Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU14150/99A 1997-11-18 1998-11-16 4-substituted-4-piperidine carboxamide derivatives Abandoned AU1415099A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US6591797P 1997-11-18 1997-11-18
US60065917 1997-11-18
GB9727214 1997-12-23
GBGB9727214.0A GB9727214D0 (en) 1997-12-23 1997-12-23 4-Substituted-4-piperdine carboxamide derivatives
PCT/US1998/024513 WO1999025685A1 (en) 1997-11-18 1998-11-16 4-substituted-4-piperidine carboxamide derivatives

Publications (1)

Publication Number Publication Date
AU1415099A true AU1415099A (en) 1999-06-07

Family

ID=26312836

Family Applications (1)

Application Number Title Priority Date Filing Date
AU14150/99A Abandoned AU1415099A (en) 1997-11-18 1998-11-16 4-substituted-4-piperidine carboxamide derivatives

Country Status (2)

Country Link
AU (1) AU1415099A (en)
WO (1) WO1999025685A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2346933A1 (en) * 1998-12-18 2000-06-22 Dupont Pharmaceuticals Company N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
WO2001023376A1 (en) 1999-09-29 2001-04-05 Ortho-Mcneil Pharmaceutical, Inc. Isonipecotamides for the treatment of integrin-mediated disorders
DE19962936A1 (en) * 1999-12-24 2001-06-28 Bayer Ag New beta-aminoacid amide derivatives, are integrin antagonists useful for treating inflammatory, autoimmune or immunological disorders e.g. asthma, diabetes or rheumatoid arthritis
JP2003519697A (en) 1999-12-28 2003-06-24 ファイザー・プロダクツ・インク Non-peptide VLA-4-dependent cell binding inhibitors useful for the treatment of inflammatory diseases, autoimmune diseases and respiratory diseases
EA005974B1 (en) 2001-02-23 2005-08-25 Мерк Энд Ко., Инк. N-substituted nonaryl-heterocyclic nmda/nr2b antagonists
WO2002081467A1 (en) 2001-04-09 2002-10-17 Ortho-Mcneil Pharmaceutical, Inc. Quinazoline and quinazoline-like compounds for the treatment of integrin-mediated disorders
TW200403058A (en) * 2002-04-19 2004-03-01 Bristol Myers Squibb Co Heterocyclo inhibitors of potassium channel function
JP4617449B2 (en) 2002-07-11 2011-01-26 ヴィキュロン ファーマシューティカルズ インコーポレイテッド N-hydroxyamide derivative having antibacterial activity
GB0310724D0 (en) * 2003-05-09 2003-06-11 Glaxo Group Ltd Chemical compounds
WO2005019177A1 (en) * 2003-08-14 2005-03-03 Icos Corporation Aminopiperidine amide derivatives as vla-1 integrin antagonists and uses thereof
GB0412865D0 (en) 2004-06-09 2004-07-14 Glaxo Group Ltd Chemical compounds
TW200610754A (en) * 2004-06-14 2006-04-01 Daiichi Seiyaku Co Vla-4 inhibitor
EP2510941A3 (en) 2007-02-20 2013-01-23 Merrimack Pharmaceuticals, Inc. Methods of treating multiple sclerosis by administration of alpha-fetoprotein in combination with an integrin antagonist
PL2288715T3 (en) 2008-04-11 2015-03-31 Merrimack Pharmaceuticals Inc Human serum albumin linkers and conjugates thereof
CN104356051A (en) * 2014-11-24 2015-02-18 苏州乔纳森新材料科技有限公司 Analgesic intermediate and synthesis method thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL90218A0 (en) * 1988-05-13 1989-12-15 Abbott Lab Retroviral protease inhibitors
TW401414B (en) * 1993-09-22 2000-08-11 Fujisawa Pharmaceutical Co <beta>-alanine derivative and a process for the preparation thereof
US5770575A (en) * 1994-03-16 1998-06-23 Ortho Pharmaceutical Corporation Nipecotic acid derivatives as antithrombotic compounds
US6248713B1 (en) * 1995-07-11 2001-06-19 Biogen, Inc. Cell adhesion inhibitors

Also Published As

Publication number Publication date
WO1999025685A1 (en) 1999-05-27

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase