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AU6561700A - Reductive methylation of tetrahydroisochinoline in a static micromixer - Google Patents

Reductive methylation of tetrahydroisochinoline in a static micromixer

Info

Publication number
AU6561700A
AU6561700A AU65617/00A AU6561700A AU6561700A AU 6561700 A AU6561700 A AU 6561700A AU 65617/00 A AU65617/00 A AU 65617/00A AU 6561700 A AU6561700 A AU 6561700A AU 6561700 A AU6561700 A AU 6561700A
Authority
AU
Australia
Prior art keywords
tetrahydroisochinoline
reductive methylation
static micromixer
micromixer
static
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU65617/00A
Other languages
English (en)
Inventor
Norbert Schwesinger
Hanns Wurziger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of AU6561700A publication Critical patent/AU6561700A/en
Abandoned legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093Microreactors, e.g. miniaturised or microfabricated reactors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B43/00Formation or introduction of functional groups containing nitrogen
    • C07B43/04Formation or introduction of functional groups containing nitrogen of amino groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/24Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/08Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with a hetero atom directly attached to the ring nitrogen atom
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781Aspects relating to microreactors
    • B01J2219/00889Mixing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
AU65617/00A 1999-07-29 2000-07-05 Reductive methylation of tetrahydroisochinoline in a static micromixer Abandoned AU6561700A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19935694 1999-07-29
DE1999135694 DE19935694A1 (de) 1999-07-29 1999-07-29 Reduktive Methylierung von Aminen im statischen Mikromischer
PCT/EP2000/006319 WO2001009100A1 (de) 1999-07-29 2000-07-05 Reduktive methylierung von tetrahydroisochinolin im statischen mikromischer

Publications (1)

Publication Number Publication Date
AU6561700A true AU6561700A (en) 2001-02-19

Family

ID=7916509

Family Applications (1)

Application Number Title Priority Date Filing Date
AU65617/00A Abandoned AU6561700A (en) 1999-07-29 2000-07-05 Reductive methylation of tetrahydroisochinoline in a static micromixer

Country Status (5)

Country Link
EP (1) EP1200407A1 (de)
JP (1) JP2003506357A (de)
AU (1) AU6561700A (de)
DE (1) DE19935694A1 (de)
WO (1) WO2001009100A1 (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0798783B2 (ja) * 1986-10-17 1995-10-25 味の素株式会社 N,N―ジメチル―α―アミノ鎖状脂肪酸の製造法
DE19511603A1 (de) * 1995-03-30 1996-10-02 Norbert Dr Ing Schwesinger Vorrichtung zum Mischen kleiner Flüssigkeitsmengen
JP3638151B2 (ja) * 1996-03-28 2005-04-13 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング 少量液体の混合デバイス
DE19708472C2 (de) * 1997-02-20 1999-02-18 Atotech Deutschland Gmbh Herstellverfahren für chemische Mikroreaktoren

Also Published As

Publication number Publication date
WO2001009100A1 (de) 2001-02-08
DE19935694A1 (de) 2001-02-01
EP1200407A1 (de) 2002-05-02
JP2003506357A (ja) 2003-02-18

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase