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AU5552698A - Pharmaceutical compositions comprising diaryl-cyclomethylenpyrazole compounds and their use as cyclooxygenase i (cox i) inhibitors - Google Patents

Pharmaceutical compositions comprising diaryl-cyclomethylenpyrazole compounds and their use as cyclooxygenase i (cox i) inhibitors

Info

Publication number
AU5552698A
AU5552698A AU55526/98A AU5552698A AU5552698A AU 5552698 A AU5552698 A AU 5552698A AU 55526/98 A AU55526/98 A AU 55526/98A AU 5552698 A AU5552698 A AU 5552698A AU 5552698 A AU5552698 A AU 5552698A
Authority
AU
Australia
Prior art keywords
cyclomethylenpyrazole
cyclooxygenase
diaryl
cox
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU55526/98A
Inventor
Marilena Giannangeli
Mario Pinza
Mauro Tomaselli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Angelini Ricerche SpA
Original Assignee
Angelini Ricerche SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angelini Ricerche SpA filed Critical Angelini Ricerche SpA
Publication of AU5552698A publication Critical patent/AU5552698A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/32—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by aldehydo- or ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/24—Sulfones; Sulfoxides having sulfone or sulfoxide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU55526/98A 1996-11-15 1997-11-12 Pharmaceutical compositions comprising diaryl-cyclomethylenpyrazole compounds and their use as cyclooxygenase i (cox i) inhibitors Abandoned AU5552698A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI96A2385 1996-11-15
IT96MI002385A IT1287174B1 (en) 1996-11-15 1996-11-15 PHARMACOLOGICALLY ACTIVE DIARYL-CYCLOMETHYLENPYRAZOLES, PROCEDURE FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM
PCT/EP1997/006398 WO1998022442A2 (en) 1996-11-15 1997-11-12 Pharmaceutical compositions comprising diaryl-cyclomethylenpyrazole compounds and their use as cyclooxygenase i (cox 1) inhibitors

Publications (1)

Publication Number Publication Date
AU5552698A true AU5552698A (en) 1998-06-10

Family

ID=11375225

Family Applications (1)

Application Number Title Priority Date Filing Date
AU55526/98A Abandoned AU5552698A (en) 1996-11-15 1997-11-12 Pharmaceutical compositions comprising diaryl-cyclomethylenpyrazole compounds and their use as cyclooxygenase i (cox i) inhibitors

Country Status (5)

Country Link
AR (1) AR009612A1 (en)
AU (1) AU5552698A (en)
IT (1) IT1287174B1 (en)
WO (1) WO1998022442A2 (en)
ZA (1) ZA9710272B (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TNSN99111A1 (en) * 1998-06-11 2005-11-10 Pfizer NOVEL SULFONYLBENZENE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
US6727238B2 (en) 1998-06-11 2004-04-27 Pfizer Inc. Sulfonylbenzene compounds as anti-inflammatory/analgesic agents
US6294558B1 (en) 1999-05-31 2001-09-25 Pfizer Inc. Sulfonylbenzene compounds as anti-inflammatory/analgesic agents
AU4308300A (en) * 1999-05-03 2000-11-17 Dr. Reddy's Research Foundation Pyrazoles having antiinflammatory activity
US6506784B1 (en) 1999-07-01 2003-01-14 3-Dimensional Pharmaceuticals, Inc. Use of 1,3-substituted pyrazol-5-yl sulfonates as pesticides
US6409988B1 (en) 1999-07-01 2002-06-25 3-Dimensional Pharmaceuticals, Inc. Radiolabeled 1-aryl pyrazoles, the synthesis thereof and the use thereof as pest GABA receptor ligands
US6518266B1 (en) 1999-07-22 2003-02-11 3-Dimensional Pharmaceuticals 1- Aryl-3-thioalkyl pyrazoles, the synthesis thereof and the use thereof as insecticides
WO2001025241A2 (en) 1999-10-06 2001-04-12 3-Dimensional Pharmaceuticals, Inc. Fused 1-(2,6-dichloro-4-trifluoromethylphenyl)-pyrazoles, the synthesis thereof and the use thereof as pesticides
US6083969A (en) * 1999-10-20 2000-07-04 Ortho-Mcneil Pharaceutical, Inc. 1,3- and 2,3-diarylcycloalkano and cycloalkeno pyrazoles as selective inhibitors of cyclooxygenase-2 and antiinflammatory agents
ES2159479B1 (en) * 1999-10-25 2002-05-01 Menarini Lab Set of therapeutic indazols consists of inhibitors of cyclooxygenase combating eg. inflammation and Alzheimer's disease
AU2001296542B2 (en) 2000-10-02 2007-10-25 Emory University Triptolide analogs for the treatment of autoimmune and inflammatory disorders
US6673818B2 (en) 2001-04-20 2004-01-06 Pharmacia Corporation Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation
AU2003279622A1 (en) 2002-06-28 2004-01-19 Nitromed, Inc. Oxime and/or hydrazone containing nitrosated and/or nitrosylated cyclooxigenase-2 selective inhibitors, compositions and methods of use
PL2266585T3 (en) 2003-05-07 2013-10-31 Osteologix As Water-soluble strontium salts for use in treatment of cartilage and/or bone conditions
CN104936960B (en) * 2012-08-16 2016-12-28 詹森药业有限公司 Pyrrolo-pyrazole as N-type calcium channel blocker
JP6262231B2 (en) * 2012-08-16 2018-01-17 ヤンセン ファーマシューティカ エヌ．ベー． Cyclopentylpyrazole as an N-type calcium channel blocker
PE20151138A1 (en) 2012-08-16 2015-08-07 Janssen Pharmaceutica Nv PYRAZOLES SUBSTITUTED AS N-TYPE CALCIUM CHANNEL BLOCKERS
US9453002B2 (en) 2013-08-16 2016-09-27 Janssen Pharmaceutica Nv Substituted imidazoles as N-type calcium channel blockers
CA3209491A1 (en) 2021-03-15 2022-09-22 Saul Yedgar Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3928378A (en) * 1974-01-30 1975-12-23 Hoechst Co American Fused bicyclic aminopyrazoles
FR2315924A1 (en) * 1975-07-03 1977-01-28 Enzypha Analgesic and antiinflammatory polymethylene pyrazole derivs. - prepd. by cyclizing 2-acyl cyclic ketones with hydrazine derivs.
US4173634A (en) * 1979-02-23 1979-11-06 E. R. Squibb & Sons, Inc. Basically-substituted tricyclic pyrazoles useful as antiinflammatory agents
CZ294630B6 (en) * 1993-11-30 2005-02-16 G. D. Searle & Co. Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation

Also Published As

Publication number Publication date
ITMI962385A1 (en) 1998-05-15
IT1287174B1 (en) 1998-08-04
WO1998022442A3 (en) 1998-07-30
WO1998022442A2 (en) 1998-05-28
ZA9710272B (en) 1998-06-10
ITMI962385A0 (en) 1996-11-15
AR009612A1 (en) 2000-04-26

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