AU2957997A - 1,2,4-oxadiazoles as adhesion-receptor antagonists - Google Patents
1,2,4-oxadiazoles as adhesion-receptor antagonistsInfo
- Publication number
- AU2957997A AU2957997A AU29579/97A AU2957997A AU2957997A AU 2957997 A AU2957997 A AU 2957997A AU 29579/97 A AU29579/97 A AU 29579/97A AU 2957997 A AU2957997 A AU 2957997A AU 2957997 A AU2957997 A AU 2957997A
- Authority
- AU
- Australia
- Prior art keywords
- oxadiazoles
- adhesion
- receptor antagonists
- antagonists
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 150000005071 1,2,4-oxadiazoles Chemical class 0.000 title 1
- 102000019997 adhesion receptor Human genes 0.000 title 1
- 108010013985 adhesion receptor Proteins 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19620041 | 1996-05-17 | ||
| DE19620041A DE19620041A1 (de) | 1996-05-17 | 1996-05-17 | Adhäsionsrezeptor-Antagonisten |
| PCT/EP1997/002555 WO1997044333A1 (de) | 1996-05-17 | 1997-05-20 | 1,2,4-oxadiazole as adhäsionsrezeptor-antagonisten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2957997A true AU2957997A (en) | 1997-12-09 |
Family
ID=7794651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU29579/97A Abandoned AU2957997A (en) | 1996-05-17 | 1997-05-20 | 1,2,4-oxadiazoles as adhesion-receptor antagonists |
Country Status (5)
| Country | Link |
|---|---|
| AR (1) | AR007160A1 (es) |
| AU (1) | AU2957997A (es) |
| DE (1) | DE19620041A1 (es) |
| WO (1) | WO1997044333A1 (es) |
| ZA (1) | ZA974234B (es) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU729488B2 (en) * | 1996-08-29 | 2001-02-01 | Merck & Co., Inc. | Compositions and methods for administering integrin receptor antagonists |
| AU742641B2 (en) | 1998-01-28 | 2002-01-10 | Shionogi & Co., Ltd. | Novel tricyclic compound |
| GB9805655D0 (en) | 1998-03-16 | 1998-05-13 | Celltech Therapeutics Ltd | Chemical compounds |
| US6521626B1 (en) | 1998-03-24 | 2003-02-18 | Celltech R&D Limited | Thiocarboxamide derivatives |
| JP2003504301A (ja) * | 1998-04-01 | 2003-02-04 | ブリストル−マイヤーズ スクイブ ファーマ カンパニー | インテグリンアンタゴニスト |
| GB9814414D0 (en) | 1998-07-03 | 1998-09-02 | Celltech Therapeutics Ltd | Chemical compounds |
| EP1100506A4 (en) * | 1998-07-29 | 2002-06-26 | Merck & Co Inc | INTEGRIN RECEPTOR ANTAGONISTS |
| GB9821061D0 (en) | 1998-09-28 | 1998-11-18 | Celltech Therapeutics Ltd | Chemical compounds |
| US6107313A (en) * | 1998-10-02 | 2000-08-22 | Combichem, Inc. | Dopamine receptor antagonists |
| GB9826174D0 (en) | 1998-11-30 | 1999-01-20 | Celltech Therapeutics Ltd | Chemical compounds |
| US6518283B1 (en) | 1999-05-28 | 2003-02-11 | Celltech R&D Limited | Squaric acid derivatives |
| US6534513B1 (en) | 1999-09-29 | 2003-03-18 | Celltech R&D Limited | Phenylalkanoic acid derivatives |
| US6455539B2 (en) | 1999-12-23 | 2002-09-24 | Celltech R&D Limited | Squaric acid derivates |
| ES2295150T3 (es) | 2000-04-17 | 2008-04-16 | Ucb Pharma, S.A. | Derivados de enamina como moleculas de adhesion celular. |
| US6403608B1 (en) | 2000-05-30 | 2002-06-11 | Celltech R&D, Ltd. | 3-Substituted isoquinolin-1-yl derivatives |
| US6545013B2 (en) | 2000-05-30 | 2003-04-08 | Celltech R&D Limited | 2,7-naphthyridine derivatives |
| US6933304B2 (en) | 2000-06-15 | 2005-08-23 | Pharmacia Corporation | Heteroarylalkanoic acids as integrin receptor antagonists |
| EP1301488A1 (en) | 2000-07-07 | 2003-04-16 | Celltech R&D Limited | Squaric acid derivatives containing a bicyclic heteroaromatic ring as integrin antagonists |
| AU2001275724A1 (en) | 2000-08-02 | 2002-02-13 | Celltech R&D Limited | 3-substituted isoquinolin-1-yl derivatives |
| US20030105144A1 (en) | 2001-04-17 | 2003-06-05 | Ping Gao | Stabilized oral pharmaceutical composition |
| US7041685B2 (en) * | 2001-06-08 | 2006-05-09 | Cytovia, Inc. | Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof |
| WO2003105771A2 (en) | 2002-06-17 | 2003-12-24 | Merck & Co., Inc. | 1-((5-aryl-1,2,4-oxadiazol-3-yl)benzyl)azetidine-3-carboxylates and 1-((5-aryl-1,2,4-oxadiazol-3-yl)benzyl)pyrrolidine-3-carboxylates as edg receptor agonists |
| AU2003297408A1 (en) | 2002-12-20 | 2004-07-22 | Pharmacia Corporation | Thiazole compounds as integrin receptor antagonists derivatives |
| WO2004058254A1 (en) * | 2002-12-20 | 2004-07-15 | Pharmacia Corporation | Heteroarylalkanoic acids as integrin receptor antagonists |
| GB0303503D0 (en) * | 2003-02-14 | 2003-03-19 | Novartis Ag | Organic compounds |
| ES2770035T3 (es) * | 2003-04-11 | 2020-06-30 | Ptc Therapeutics Inc | Compuesto de ácido 1,2,4-oxadiazol benzoico y su uso para la supresión sin sentido y el tratamiento de enfermedades |
| WO2005058848A1 (en) | 2003-12-17 | 2005-06-30 | Merck & Co., Inc. | (3,4-disubstituted)propanoic carboxylates as s1p (edg) receptor agonists |
| JP2008515992A (ja) | 2004-10-13 | 2008-05-15 | ピーティーシー セラピューティクス，インコーポレーテッド | 体細胞変異に起因する疾患の阻止／治療用医薬を製造するための規定化合物の使用 |
| US20080306124A1 (en) * | 2005-06-08 | 2008-12-11 | Rainer Albert | Polycyclic Oxadiazoles or I Soxazoles and Their Use as Sip Receptor Ligands |
| US20090325924A1 (en) * | 2005-06-30 | 2009-12-31 | Stuart Edward | GPCR Agonists |
| WO2007117438A2 (en) | 2006-03-30 | 2007-10-18 | Ptc Therapeutics, Inc. | Methods for the production of functional protein from dna having a nonsense mutation and the treatment of disorders associated therewith |
| LT3357911T (lt) | 2006-06-26 | 2022-08-10 | Akebia Therapeutics Inc. | Prolilo hidroksilazės inhibitoriai ir naudojimo būdai |
| JO2701B1 (en) | 2006-12-21 | 2013-03-03 | جلاكسو جروب ليميتد | Vehicles |
| KR101273765B1 (ko) * | 2008-06-24 | 2013-06-12 | 아이알엠 엘엘씨 | Ｇ 단백질-커플링된 수용체를 조정하는 화합물 및 방법 |
| NO2686520T3 (es) | 2011-06-06 | 2018-03-17 | ||
| JP2014522410A (ja) | 2011-06-06 | 2014-09-04 | アケビア セラピューティクス インコーポレイテッド | がん治療のための方法として低酸素誘導因子−２αを安定化するための、化合物および組成物 |
| SG11201509998WA (en) | 2013-06-13 | 2016-01-28 | Akebia Therapeutics Inc | Compositions and methods for treating anemia |
| RU2021125455A (ru) | 2013-11-15 | 2021-10-05 | Экебиа Терапьютикс, Инк. | Твердые формы { [5-(3-хлорфенил)-3-гидроксипиридин-2-карбонил]амино} уксусной кислоты, их композиции и применения |
| CA2942147C (en) | 2014-03-06 | 2022-12-13 | Ptc Therapeutics, Inc. | Pharmaceutical compositions and salts of a 1,2,4-oxadiazole benzoic acid |
| BR112017015852A2 (pt) | 2015-01-23 | 2018-03-27 | Akebia Therapeutics Inc | forma de cristal, sal hemicálcico, sal hemicálcico di-hidratado, sal monossódico hidratado, sal bissódico monoidratado, sal monossódico anidro e método para preparar o composto 1 |
| TWI794725B (zh) | 2015-04-01 | 2023-03-01 | 美商阿克比治療有限公司 | 用於治療貧血之組合物及方法 |
| CN108348527A (zh) | 2015-10-30 | 2018-07-31 | Ptc医疗公司 | 用于治疗癫痫的方法 |
| EP3790863A1 (en) | 2018-05-09 | 2021-03-17 | Akebia Therapeutics Inc. | Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid |
| US11524939B2 (en) | 2019-11-13 | 2022-12-13 | Akebia Therapeutics, Inc. | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid |
| GB202209228D0 (en) * | 2022-06-23 | 2022-08-10 | Univ Strathclyde | Modified amino acids and uses thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB935523A (en) * | 1961-06-17 | 1963-08-28 | Acraf | New sulphamido-oxadiazoles |
| JPS51143669A (en) * | 1975-06-06 | 1976-12-10 | Takeda Chem Ind Ltd | A process for preparing 1,2,4- oxadiazole derivatives |
| JPS52272A (en) * | 1975-10-17 | 1977-01-05 | Takeda Chem Ind Ltd | Process for preparing 1,2,4-oxadiazole derivatives |
| US4135910A (en) * | 1977-05-12 | 1979-01-23 | Monsanto Company | Oxadiazol-3-yl-benzoates as plant growth regulants |
| WO1994022846A1 (en) * | 1993-03-30 | 1994-10-13 | Pfizer Inc. | Compounds enhancing antitumor activity of other cytotoxic agents |
-
1996
- 1996-05-17 DE DE19620041A patent/DE19620041A1/de not_active Withdrawn
-
1997
- 1997-05-15 ZA ZA9704234A patent/ZA974234B/xx unknown
- 1997-05-16 AR ARP970102054A patent/AR007160A1/es unknown
- 1997-05-20 WO PCT/EP1997/002555 patent/WO1997044333A1/de not_active Ceased
- 1997-05-20 AU AU29579/97A patent/AU2957997A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AR007160A1 (es) | 1999-10-13 |
| DE19620041A1 (de) | 1998-01-29 |
| WO1997044333A1 (de) | 1997-11-27 |
| ZA974234B (en) | 1997-12-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2957997A (en) | 1,2,4-oxadiazoles as adhesion-receptor antagonists | |
| AU1251697A (en) | New substituted oxazolidinones | |
| AU4073997A (en) | 1,4-heterocyclic metallprotease inhibitors | |
| AU1730497A (en) | Fungicidal 1,2,4-oxadiazoles and analogues | |
| HRP970454B1 (en) | Substituted 6,5-hetero-bicyclic derivatives | |
| ZA977652B (en) | Substituted 6,6-hetero-bicyclic derivatives | |
| AUPN772396A0 (en) | The kouris centri-turbine generator | |
| AU1642095A (en) | 3,5-disubstituted tetrahydrofuran-2-ones | |
| AU8441798A (en) | Tricyclically substituted oxazolidinones | |
| AU6636598A (en) | Novel 3,4-dialkoxyphenyl derivatives and the use thereof | |
| AU1416195A (en) | Substituted 1,2,3,4-tetrahydro-5-nitro pyrimidines | |
| AU5530998A (en) | Relatively stable (1,3-disubstitutedimidazol-2-ylidene)-type carbenes | |
| AU2964899A (en) | 2,4-dioxo-5-arylidenimino-1,3-pyrimidines | |
| AU7449998A (en) | 2,3-dihydrobenzofuran derivatives | |
| AUPP003297A0 (en) | 4,5-diaryloxazole compounds | |
| AU5692398A (en) | Substituted 5-amino-1,3,4-thiadiazole-2-thiones | |
| AU1513597A (en) | 1,25-dihydroxy-16,22,23-trisdehydro-cholecalciferol derivatives | |
| AU6904698A (en) | Herbicidal 3,5-difluoropyridines | |
| AU3006797A (en) | Substituted 1, 3-benzodioxoles | |
| AU2137095A (en) | Heterocyclyl-1,3,4-thiadiazolyloxyacetamides | |
| AU1303897A (en) | Herbicidal 1,2,4,6-thiatriazines | |
| AU1375797A (en) | Substituted 1,2,4,6-thiatriazines useful as herbicides | |
| HK1018061A (en) | Substituted 1,3-benzodioxoles | |
| AU4263999A (en) | Substituted 1,3-diaza-2-(thi)oxo-cycloalkanes | |
| HK1012395A (en) | Biphenylcarboxamides useful as 5-ht1d antagonists |