AU2555997A - Inhibitors of farnesyl-protein transferase - Google Patents
Inhibitors of farnesyl-protein transferaseInfo
- Publication number
- AU2555997A AU2555997A AU25559/97A AU2555997A AU2555997A AU 2555997 A AU2555997 A AU 2555997A AU 25559/97 A AU25559/97 A AU 25559/97A AU 2555997 A AU2555997 A AU 2555997A AU 2555997 A AU2555997 A AU 2555997A
- Authority
- AU
- Australia
- Prior art keywords
- farnesyl
- inhibitors
- protein transferase
- transferase
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Virology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1459496P | 1996-04-03 | 1996-04-03 | |
| US60014594 | 1996-04-03 | ||
| GB9614316 | 1996-07-08 | ||
| GBGB9614316.9A GB9614316D0 (en) | 1996-07-08 | 1996-07-08 | Inhibitors of farnesyl-protein transferase |
| PCT/US1997/005240 WO1997036879A1 (en) | 1996-04-03 | 1997-03-31 | Inhibitors of farnesyl-protein transferase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2555997A true AU2555997A (en) | 1997-10-22 |
Family
ID=26309662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU25559/97A Abandoned AU2555997A (en) | 1996-04-03 | 1997-03-31 | Inhibitors of farnesyl-protein transferase |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0891337A1 (en) |
| JP (1) | JP2000507587A (en) |
| AU (1) | AU2555997A (en) |
| CA (1) | CA2250203A1 (en) |
| WO (1) | WO1997036879A1 (en) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999020609A1 (en) * | 1997-10-17 | 1999-04-29 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| NZ509241A (en) | 1998-08-07 | 2003-08-29 | Du Pont Pharm Co | Succinoylamino lactams as inhibitors of alpha-beta protein production |
| HRP990246A2 (en) | 1998-08-07 | 2000-06-30 | Du Pont Pharm Co | Succinoylamino benzodiazepines as inhibitors of a beta protein production |
| IL142816A0 (en) | 1998-12-24 | 2002-03-10 | Du Pont Pharm Co | SUCCINOYLAMINO BENZODIAZEPINES AS INHIBITORS OF Aβ PROTEIN PRODUCTION |
| US6503902B2 (en) | 1999-09-13 | 2003-01-07 | Bristol-Myers Squibb Pharma Company | Hydroxyalkanoylaminolactams and related structures as inhibitors of a β protein production |
| US6960576B2 (en) | 1999-09-13 | 2005-11-01 | Bristol-Myers Squibb Pharma Company | Hydroxyalkanoylaminolactams and related structures as inhibitors of Aβ protein production |
| WO2001027108A1 (en) | 1999-10-08 | 2001-04-19 | Bristol-Myers Squibb Pharma Company | AMINO LACTAM SULFONAMIDES AS INHIBITORS OF Aβ PROTEIN PRODUCTION |
| US6525044B2 (en) | 2000-02-17 | 2003-02-25 | Bristol-Myers Squibb Company | Succinoylamino carbocycles and heterocycles as inhibitors of a-β protein production |
| EP1268433A1 (en) | 2000-04-03 | 2003-01-02 | Bristol-Myers Squibb Pharma Company | Cyclic lactams as inhibitors of a-beta-protein production |
| BR0110051A (en) | 2000-04-03 | 2004-12-07 | Bristol Myers Squibb Pharma Co | Compound, Compound Use, Pharmaceutical Composition and Method of Treatment of Alzheimer's Disease |
| US6632812B2 (en) | 2000-04-11 | 2003-10-14 | Dupont Pharmaceuticals Company | Substituted lactams as inhibitors of Aβ protein production |
| WO2001092235A1 (en) | 2000-06-01 | 2001-12-06 | Bristol-Myers Squibb Pharma Company | LACTAMS SUBSTITUTED BY CYCLIC SUCCINATES AS INHIBITORS OF Aβ PROTEIN PRODUCTION |
| US7799342B2 (en) | 2000-12-06 | 2010-09-21 | Wyeth Llc | Fast dissolving tablet |
| CA2622592A1 (en) * | 2005-09-19 | 2007-03-29 | Arrow Therapeutics Limited | Benzodiazepine derivatives for treating hepatitis c infection |
| CA2650498A1 (en) | 2006-03-31 | 2007-10-11 | Rubicon Research Private Limited | Orally disintegrating tablets |
| NZ580801A (en) | 2007-05-10 | 2012-09-28 | Bristol Myers Squibb Co | Aryl- and heteroaryl-substituted tetrahydrobenzo-1,4-diazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin |
| EP2384742A1 (en) | 2010-05-03 | 2011-11-09 | The Jordanian Pharmaceutical Manufacturing Co. | Pharmaceutical excipient, method for its preparation and use thereof |
| TWI530489B (en) | 2011-03-22 | 2016-04-21 | 必治妥美雅史谷比公司 | Bis(fluoroalkyl)-1,4-benzodiazepine compound |
| CN104797569A (en) | 2012-09-21 | 2015-07-22 | 百时美施贵宝公司 | Substituted 1,5-benzodiazepinone compounds |
| CN105308030A (en) * | 2012-09-21 | 2016-02-03 | 百时美施贵宝公司 | Alkyl, fluoroalkyl-1,4-benzodiazepinone compounds |
| WO2014047397A1 (en) | 2012-09-21 | 2014-03-27 | Bristol-Myers Squibb Company | Fluoroalkyl and fluorocycloalkyl 1,4-benzodiazepinone compounds as notch|inhibitors |
| TWI614238B (en) | 2012-09-21 | 2018-02-11 | 必治妥美雅史谷比公司 | Bis(fluoroalkyl)-1,4-benzodiazepine compounds and prodrugs thereof |
| US9273075B2 (en) | 2012-09-21 | 2016-03-01 | Bristol-Myers Squibb Company | Prodrugs of 1,4-benzodiazepinone compounds |
| CN104854094A (en) | 2012-09-21 | 2015-08-19 | 百时美施贵宝公司 | Fluoroalkyl dibenzodiazepinone compounds |
| US9242940B2 (en) | 2012-09-21 | 2016-01-26 | Bristol-Myers Squibb Company | N-substituted bis(fluoroalkyl)-1,4-benzodiazepinone compounds |
| US9249157B2 (en) | 2012-09-21 | 2016-02-02 | Bristol-Myers Squibb Company | Tricyclic heterocycle compounds |
| CN104822677A (en) | 2012-09-21 | 2015-08-05 | 百时美施贵宝公司 | Fluoroalkyl-1,4-benzodiazepinone compounds |
| JP2016515625A (en) | 2013-04-04 | 2016-05-30 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | Combination therapy to treat proliferative diseases |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6909194A (en) * | 1993-05-14 | 1994-12-12 | Board Of Regents, The University Of Texas System | Preparation of n-cyanodithioimino-carbonates and 3-mercapto-5-amino-1h-1,2,4-triazole |
-
1997
- 1997-03-31 EP EP97917131A patent/EP0891337A1/en not_active Withdrawn
- 1997-03-31 JP JP9535513A patent/JP2000507587A/en active Pending
- 1997-03-31 AU AU25559/97A patent/AU2555997A/en not_active Abandoned
- 1997-03-31 WO PCT/US1997/005240 patent/WO1997036879A1/en not_active Ceased
- 1997-03-31 CA CA002250203A patent/CA2250203A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997036879A1 (en) | 1997-10-09 |
| EP0891337A1 (en) | 1999-01-20 |
| CA2250203A1 (en) | 1997-10-09 |
| JP2000507587A (en) | 2000-06-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU703203B2 (en) | Inhibitors of farnesyl-protein transferase | |
| AU2734797A (en) | Inhibitors of farnesyl-protein transferase | |
| AU2670297A (en) | Inhibitors of farnesyl-protein transferase | |
| AU2593097A (en) | Inhibitors of farnesyl-protein transferase | |
| AU2253097A (en) | Inhibitors of farnesyl-protein transferase | |
| AU2430197A (en) | Inhibitors of farnesyl-protein transferase | |
| AU1988495A (en) | Inhibitors of farnesyl-protein transferase | |
| AU2555997A (en) | Inhibitors of farnesyl-protein transferase | |
| AU3373195A (en) | Inhibitors of farnesyl-protein transferase | |
| GB9604311D0 (en) | Inhibitors of farnesyl-protein transferase | |
| AU2598897A (en) | Inhibitors of farnesyl-protein transferase | |
| AU2605897A (en) | Inhibitors of farnesyl-protein transferase | |
| AU2552497A (en) | Inhibitors of farnesyl-protein transferase | |
| AU2605797A (en) | Inhibitors of farnesyl-protein transferase | |
| AU2587597A (en) | Inhibitors of farnesyl-protein transferase | |
| AU1851697A (en) | Inhibitors of farnesyl-protein transferase | |
| AU2432597A (en) | Inhibitors of farnesyl-protein transferase | |
| AU2432697A (en) | Inhibitors of farnesyl-protein transferase | |
| AU2430397A (en) | Inhibitors of farnesyl-protein transferase | |
| AU2554897A (en) | Inhibitors of farnesyl-protein transferase | |
| AU2600597A (en) | Inhibitors of farnesyl-protein transferase | |
| AU2602097A (en) | Inhibitors of farnesyl-protein transferase | |
| AU2593297A (en) | Inhibitors of farnesyl-protein transferase | |
| AU1952697A (en) | Inhibitors of farnesyl-protein transferase | |
| AU2587997A (en) | Inhibitors of farnesyl-protein transferase |