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AU2179688A - Recombinant eukaryotic cells production interleukin-2, process and vectors for their preparation and process for the preparation of interleukin-2 - Google Patents

Recombinant eukaryotic cells production interleukin-2, process and vectors for their preparation and process for the preparation of interleukin-2

Info

Publication number
AU2179688A
AU2179688A AU21796/88A AU2179688A AU2179688A AU 2179688 A AU2179688 A AU 2179688A AU 21796/88 A AU21796/88 A AU 21796/88A AU 2179688 A AU2179688 A AU 2179688A AU 2179688 A AU2179688 A AU 2179688A
Authority
AU
Australia
Prior art keywords
preparation
interleukin
vectors
eukaryotic cells
recombinant eukaryotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU21796/88A
Other versions
AU606453B2 (en
Inventor
Johannes Lupker
Brigitte Miloux
Willem Roskam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Publication of AU2179688A publication Critical patent/AU2179688A/en
Application granted granted Critical
Publication of AU606453B2 publication Critical patent/AU606453B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/55—IL-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AU21796/88A 1987-09-01 1988-09-01 Recombinant eukaryotic cells production interleukin-2, process and vectors for their preparation and process for the preparation of interleukin-2 Ceased AU606453B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8712166A FR2619719B1 (en) 1987-09-01 1987-09-01 PROCESS FOR OBTAINING INTERLEUKIN-2 FROM EUKARYOTIC CELLS, VECTORS NECESSARY FOR ITS IMPLEMENTATION AND HIGHLY PRODUCING CELL LINES
FR8712166 1987-09-01

Publications (2)

Publication Number Publication Date
AU2179688A true AU2179688A (en) 1989-03-02
AU606453B2 AU606453B2 (en) 1991-02-07

Family

ID=9354552

Family Applications (1)

Application Number Title Priority Date Filing Date
AU21796/88A Ceased AU606453B2 (en) 1987-09-01 1988-09-01 Recombinant eukaryotic cells production interleukin-2, process and vectors for their preparation and process for the preparation of interleukin-2

Country Status (12)

Country Link
EP (1) EP0307285A1 (en)
JP (1) JPH01165373A (en)
KR (1) KR890005264A (en)
AU (1) AU606453B2 (en)
DK (1) DK467188A (en)
FI (1) FI884036L (en)
FR (1) FR2619719B1 (en)
IL (1) IL87622A0 (en)
NO (1) NO883883L (en)
NZ (1) NZ225983A (en)
PT (1) PT88372B (en)
ZA (1) ZA886517B (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU603576B2 (en) * 1986-05-12 1990-11-22 F. Hoffmann-La Roche Ag Enhanced expression of human interleukin-2 in mammalian cells
WO1990015142A1 (en) * 1989-06-09 1990-12-13 Gropep Pty. Ltd. Growth hormone fusion proteins
US5679771A (en) * 1990-02-13 1997-10-21 Gropep Pty. Ltd. Method for treating intestinal diseases
US6083725A (en) * 1996-09-13 2000-07-04 Transkaryotic Therapies, Inc. Tranfected human cells expressing human α-galactosidase A protein
US7833742B2 (en) 2002-04-25 2010-11-16 Shire Human Genetic Therapies, Inc. Treatment of α-galactosidase A deficiency

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5417970A (en) * 1988-10-21 1995-05-23 Sanofi Drugs containing a glycosylated interleukin-2
FR2639232A1 (en) * 1988-10-21 1990-05-25 Sanofi Sa DRUGS CONTAINING A GLYCOSYLATED INTERLEUKIN-2
JP2002509426A (en) * 1996-05-01 2002-03-26 ジェニトープ コーポレーション Vaccines for treating lymphoma and leukemia
US5776746A (en) 1996-05-01 1998-07-07 Genitope Corporation Gene amplification methods
EP2327775A3 (en) * 1996-09-13 2012-10-24 Shire Human Genetic Therapies, Inc. Therapy for alpha-galactosidase a deficiency
CA2309766C (en) 1997-11-20 2008-09-30 Vical Incorporated Treatment of cancer using cytokine-expressing polynucleotides and compositions therefor
KR20020043448A (en) * 2000-12-04 2002-06-10 리송알렉스인근 Recombinant protein human interleukin-2 and manufacturing method of same
IL140110A0 (en) * 2000-12-05 2002-02-10 Applied Research Systems Improvement of homogeneity and secretion of recombinant proteins in mammalian systems
MA40094B1 (en) 2014-08-06 2022-05-31 Univ Miami Interleukin-2/interleukin-2 alpha receptor fusion proteins and methods of use
MX2020009975A (en) 2018-03-28 2020-10-12 Bristol Myers Squibb Co Interleukin-2/interleukin-2 receptor alpha fusion proteins and methods of use.
WO2020264321A1 (en) * 2019-06-26 2020-12-30 The Johns Hopkins University Methods and materials for targeted expansion of immune effector cells

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0172619A1 (en) * 1984-06-20 1986-02-26 Takeda Chemical Industries, Ltd. Novel transformant and use thereof
US4992367A (en) * 1986-05-12 1991-02-12 Hoffmann-La Roche Inc. Enhanced expression of human interleukin-2 in mammalian cells

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU603576B2 (en) * 1986-05-12 1990-11-22 F. Hoffmann-La Roche Ag Enhanced expression of human interleukin-2 in mammalian cells
WO1990015142A1 (en) * 1989-06-09 1990-12-13 Gropep Pty. Ltd. Growth hormone fusion proteins
US5330971A (en) * 1989-06-09 1994-07-19 Gropep Pty. Ltd. Growth hormone fusion proteins, methods of production, and methods of treatment
US5679771A (en) * 1990-02-13 1997-10-21 Gropep Pty. Ltd. Method for treating intestinal diseases
US6083725A (en) * 1996-09-13 2000-07-04 Transkaryotic Therapies, Inc. Tranfected human cells expressing human α-galactosidase A protein
US6395884B1 (en) 1996-09-13 2002-05-28 Transkaryotic Therapies, Inc. Therapy for α-galactosidase a deficiency
US6566099B1 (en) 1996-09-13 2003-05-20 Transkaryotic Therapies, Inc. Nucleic acid encoding a chimeric polypeptide
US7122354B2 (en) 1996-09-13 2006-10-17 Transkaryotic Therapies, Inc. Nucleic acid encoding a chimeric polypeptide
US7833742B2 (en) 2002-04-25 2010-11-16 Shire Human Genetic Therapies, Inc. Treatment of α-galactosidase A deficiency
US9267166B2 (en) 2002-04-25 2016-02-23 Shire Human Genetic Therapies, Inc. Treatment of α-galactosidase A deficiency
US9523113B2 (en) 2002-04-25 2016-12-20 Shire Human Genetic Therapies, Inc. Treatment of α-galactosidase A deficiency

Also Published As

Publication number Publication date
NZ225983A (en) 1990-09-26
FR2619719A1 (en) 1989-03-03
EP0307285A1 (en) 1989-03-15
DK467188A (en) 1989-03-02
FI884036A7 (en) 1989-03-02
FI884036A0 (en) 1988-09-01
FR2619719B1 (en) 1991-05-10
ZA886517B (en) 1989-05-30
IL87622A0 (en) 1989-01-31
JPH01165373A (en) 1989-06-29
KR890005264A (en) 1989-05-13
DK467188D0 (en) 1988-08-19
PT88372B (en) 1993-04-30
AU606453B2 (en) 1991-02-07
NO883883D0 (en) 1988-08-31
PT88372A (en) 1989-07-31
FI884036L (en) 1989-03-02
NO883883L (en) 1989-03-02

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