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AU1446988A - Genetic engineering process for the preparation of polypeptides - Google Patents

Genetic engineering process for the preparation of polypeptides

Info

Publication number
AU1446988A
AU1446988A AU14469/88A AU1446988A AU1446988A AU 1446988 A AU1446988 A AU 1446988A AU 14469/88 A AU14469/88 A AU 14469/88A AU 1446988 A AU1446988 A AU 1446988A AU 1446988 A AU1446988 A AU 1446988A
Authority
AU
Australia
Prior art keywords
polypeptides
preparation
genetic engineering
engineering process
genetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU14469/88A
Other versions
AU603883B2 (en
Inventor
Wolfgang Becker
Hans Willi Jansen
Waldemar Wetekam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of AU1446988A publication Critical patent/AU1446988A/en
Application granted granted Critical
Publication of AU603883B2 publication Critical patent/AU603883B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/585Calcitonins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2468Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on beta-galactose-glycoside bonds, e.g. carrageenases (3.2.1.83; 3.2.1.157); beta-agarase (3.2.1.81)
    • C12N9/2471Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01023Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/61Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
AU14469/88A 1987-04-11 1988-04-11 Genetic engineering process for the preparation of polypeptides Ceased AU603883B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3712361 1987-04-11
DE3712361 1987-04-11
DE3805150 1988-02-19
DE3805150A DE3805150A1 (en) 1987-04-11 1988-02-19 GENE TECHNOLOGICAL METHOD FOR PRODUCING POLYPEPTIDES

Publications (2)

Publication Number Publication Date
AU1446988A true AU1446988A (en) 1988-10-13
AU603883B2 AU603883B2 (en) 1990-11-29

Family

ID=25854588

Family Applications (1)

Application Number Title Priority Date Filing Date
AU14469/88A Ceased AU603883B2 (en) 1987-04-11 1988-04-11 Genetic engineering process for the preparation of polypeptides

Country Status (12)

Country Link
EP (1) EP0286956B1 (en)
JP (1) JPS63263087A (en)
KR (1) KR880012758A (en)
AU (1) AU603883B2 (en)
DE (2) DE3805150A1 (en)
DK (1) DK196188A (en)
FI (1) FI881617A7 (en)
GR (1) GR3007417T3 (en)
IL (1) IL86023A (en)
NO (1) NO881548L (en)
NZ (1) NZ224184A (en)
PT (1) PT87211B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU607973B2 (en) * 1987-03-04 1991-03-21 Asubio Pharma Co., Ltd. Process for production of physiologically active peptide containing cysteine residue
AU617999B2 (en) * 1987-05-19 1991-12-12 Hoechst Aktiengesellschaft A genetic engineering process for the preparation of angiogenins

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3844211A1 (en) * 1988-12-29 1990-07-05 Hoechst Ag NEW INSULINE DERIVATIVES, THE PROCESS FOR THEIR PRODUCTION, THEIR USE AND A PHARMACEUTICAL PREPARATION CONTAINING THEM
US5179196A (en) * 1989-05-04 1993-01-12 Sri International Purification of proteins employing ctap-iii fusions
US5527687A (en) * 1993-05-25 1996-06-18 American Cyanamid Company Enzyme induction screen for ergosterol biosynthesis inhibitors
CA2198966C (en) * 1996-03-04 2011-06-21 Yuji Suzuki Method for cleaving chimeric protein using processing enzyme
ATE264871T1 (en) 1996-07-26 2004-05-15 Aventis Pharma Gmbh INSULIN DERIVATIVES WITH INCREASED ZINC BINDING
DE19825447A1 (en) 1998-06-06 1999-12-09 Hoechst Marion Roussel De Gmbh New insulin analogues with increased zinc formation
WO2014164466A1 (en) * 2013-03-12 2014-10-09 E. I. Du Pont De Nemours And Company Methods for the identification of variant recognition sites for rare-cutting engineered double-strand-break-inducing agents and compositions and uses thereof
KR20200080747A (en) 2018-12-27 2020-07-07 주식회사 폴루스 An Enzymatic Conversion Composition for Producing Insulin from Proinsulin and a Method for Producing Insulin from Proinsulin Using the Same
KR20200080748A (en) 2018-12-27 2020-07-07 주식회사 폴루스 A Method for Purifying Proinsulin Using Anion Exchange Chromatography

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE871782A (en) * 1977-11-08 1979-05-07 Genentech Inc PROCESS ALLOWING THE MICROBIAL EXPRESSION OF POLYPEPTIDES AND APPROPRIATE MEANS
JPS6028994A (en) * 1983-07-08 1985-02-14 Wakunaga Seiyaku Kk (21-leucine) human urogastrone, corresponding gene, corresponding recombinant plasmid, transformed cell and their preparation
WO1985000831A1 (en) * 1983-08-10 1985-02-28 Amgen Microbial expression of insulin-like growth factor
DK175535B1 (en) * 1987-03-04 2004-11-29 Daiichi Suntory Pharma Co Ltd Process for preparing a physiologically active cysteine-containing peptide
DE3715033A1 (en) * 1987-05-06 1988-11-17 Hoechst Ag METHOD FOR ISOLATING FUSION PROTEINS

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU607973B2 (en) * 1987-03-04 1991-03-21 Asubio Pharma Co., Ltd. Process for production of physiologically active peptide containing cysteine residue
AU617999B2 (en) * 1987-05-19 1991-12-12 Hoechst Aktiengesellschaft A genetic engineering process for the preparation of angiogenins

Also Published As

Publication number Publication date
GR3007417T3 (en) 1993-07-30
NO881548L (en) 1988-10-12
FI881617A0 (en) 1988-04-07
AU603883B2 (en) 1990-11-29
DK196188A (en) 1988-10-12
KR880012758A (en) 1988-11-29
NO881548D0 (en) 1988-04-08
DE3805150A1 (en) 1988-10-20
PT87211B (en) 1992-07-31
EP0286956B1 (en) 1992-12-30
IL86023A0 (en) 1988-09-30
JPS63263087A (en) 1988-10-31
FI881617A7 (en) 1988-10-12
NZ224184A (en) 1989-10-27
IL86023A (en) 1993-01-31
DK196188D0 (en) 1988-04-11
EP0286956A3 (en) 1989-04-05
EP0286956A2 (en) 1988-10-19
DE3877035D1 (en) 1993-02-11
PT87211A (en) 1988-05-01

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