AU2002219418A1 - Compositions of estrogen-cyclodextrin complexes - Google Patents

Compositions of estrogen-cyclodextrin complexes

Info

Publication number: AU2002219418A1
Authority: AU; Australia
Prior art keywords: estrogen; compositions; cyclodextrin complexes; cyclodextrin; complexes
Prior art date: 2000-12-20
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

AU2002219418A

Other versions

AU2002219418B2 (en

AU2002219418C1 (en

Inventor

Thomas Backensfeld

Wolfgang Heil

Ralph Lipp

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bayer Intellectual Property GmbH

Original Assignee

Bayer Intellectual Property GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-12-20

Filing date

2001-12-20

Publication date

2002-09-05

2000-12-20 Priority claimed from EP00610135A external-priority patent/EP1216713A1/en

2001-12-20 Application filed by Bayer Intellectual Property GmbH filed Critical Bayer Intellectual Property GmbH

2002-07-01 Publication of AU2002219418C1 publication Critical patent/AU2002219418C1/en

2002-07-01 Application granted granted Critical

2002-09-05 Publication of AU2002219418A1 publication Critical patent/AU2002219418A1/en

2006-07-06 Publication of AU2002219418B2 publication Critical patent/AU2002219418B2/en

2006-10-04 Priority to AU2006225232A priority Critical patent/AU2006225232B8/en

2009-10-08 Assigned to BAYER SCHERING PHARMA AKTIENGESELLSCHAFT reassignment BAYER SCHERING PHARMA AKTIENGESELLSCHAFT Request to Amend Deed and Register Assignors: SCHERING AKTIENGESELLSCHAFT

2011-08-25 Assigned to BAYER PHARMA AKTIENGESELLSCHAFT reassignment BAYER PHARMA AKTIENGESELLSCHAFT Request to Amend Deed and Register Assignors: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT

2013-12-05 Assigned to BAYER INTELLECTUAL PROPERTY GMBH reassignment BAYER INTELLECTUAL PROPERTY GMBH Request for Assignment Assignors: BAYER PHARMA AKTIENGESELLSCHAFT

2021-12-20 Anticipated expiration legal-status Critical

Status Expired legal-status Critical Current

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
AU2006225232A AU2006225232B8 (en)	2000-12-20	2006-10-04	Compositions of estrogen-cyclodextrin complexes

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US25648400P	2000-12-20	2000-12-20
EP00610135A EP1216713A1 (en)	2000-12-20	2000-12-20	Compositions of estrogen-cyclodextrin complexes
EP00610135.6		2000-12-20
US60/256,484		2000-12-20
PCT/IB2001/002605 WO2002049675A1 (en)	2000-12-20	2001-12-20	Compositions of estrogen-cyclodextrin complexes

Related Child Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2006225232A Division AU2006225232B8 (en)	2000-12-20	2006-10-04	Compositions of estrogen-cyclodextrin complexes

Publications (3)

Publication Number	Publication Date
AU2002219418C1 AU2002219418C1 (en)	2002-07-01
AU2002219418A1 true AU2002219418A1 (en)	2002-09-05
AU2002219418B2 AU2002219418B2 (en)	2006-07-06

Family

ID=26073713

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
AU1941802A Pending AU1941802A (en)	2000-12-20	2001-12-20	Compositions of estrogen-cyclodextrin complexes
AU2002219418A Expired AU2002219418B2 (en)	2000-12-20	2001-12-20	Compositions of estrogen-cyclodextrin complexes
AU2006225232A Expired AU2006225232B8 (en)	2000-12-20	2006-10-04	Compositions of estrogen-cyclodextrin complexes

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AU1941802A Pending AU1941802A (en)	2000-12-20	2001-12-20	Compositions of estrogen-cyclodextrin complexes

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AU2006225232A Expired AU2006225232B8 (en)	2000-12-20	2006-10-04	Compositions of estrogen-cyclodextrin complexes

Country Status (29)

Country	Link
US (3)	US6958326B2 (en)
EP (3)	EP1216713A1 (en)
JP (2)	JP4782364B2 (en)
KR (3)	KR101275372B1 (en)
CN (1)	CN1268396C (en)
AT (1)	ATE311204T1 (en)
AU (3)	AU1941802A (en)
BG (1)	BG66050B1 (en)
BR (1)	BRPI0116417B8 (en)
CA (2)	CA2432151C (en)
CY (2)	CY1106071T1 (en)
CZ (2)	CZ305671B6 (en)
DE (1)	DE60115499T2 (en)
DK (2)	DK1632237T3 (en)
EA (2)	EA011275B1 (en)
EE (1)	EE05282B1 (en)
ES (2)	ES2249387T3 (en)
HR (2)	HRP20030592B1 (en)
HU (2)	HU230299B1 (en)
IL (3)	IL156437A0 (en)
LT (1)	LT1632237T (en)
ME (1)	MEP38108A (en)
MX (1)	MXPA03005636A (en)
NO (1)	NO332726B1 (en)
NZ (1)	NZ526847A (en)
RS (2)	RS50362B (en)
SI (2)	SI1632237T1 (en)
SK (1)	SK287500B6 (en)
WO (1)	WO2002049675A1 (en)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6787531B1 (en) *	1999-08-31	2004-09-07	Schering Ag	Pharmaceutical composition for use as a contraceptive
US20020132801A1 (en) *	2001-01-11	2002-09-19	Schering Aktiengesellschaft	Drospirenone for hormone replacement therapy
US6992075B2 (en) *	2003-04-04	2006-01-31	Barr Laboratories, Inc.	C(14) estrogenic compounds
EP2260834A2 (en) *	2003-09-03	2010-12-15	Mallinckrodt Inc.	Granular sustained release preparation and production thereof
WO2005111224A2 (en) *	2004-05-18	2005-11-24	Kemijski Institut	Water-soluble coenzyme q10 in inclusion complex with beta-cyclodextrin, process of preparing, and use thereof
US8022053B2 (en)	2004-11-02	2011-09-20	Bayer Schering Pharma Aktiengesellschaft	Oral solid dosage forms containing a low dose of estradiol
UY29527A1 (en)	2005-05-13	2006-12-29	Schering Ag	PHARMACCUTIC COMPOSITION CONTAINING GESTRGENS AND / OR ESTRNGENS AND 5-METHYL - (6S) - TETRHYDROPHOLATE.
US20070287684A1 (en)	2006-05-22	2007-12-13	Irshad Chaudry	Methods and compositions for treating trauma-hemorrhage using estrogen and derivatives thereof
US8617597B2 (en)	2006-07-06	2013-12-31	Bayer Intellectual Property Gmbh	Pharmaceutical composition containing a tetrahydrofolic acid
CN101489563A (en) *	2006-07-06	2009-07-22	拜耳先灵医药股份有限公司	Pharmaceutical preparations for contraception and for preventing the risk of congenital malformations
ES2327665T3 (en) *	2006-08-10	2009-11-02	JENAPHARM GMBH & CO. KG	PERORAL MEDICINAL FORM WITH DIENOGEST AND ETHYLESTRADIOL FOR CONTRACEPTION.
HUP0700826A3 (en) *	2007-12-20	2010-03-29	Richter Gedeon Nyrt	Coated tablet containing drospirenone and process for producing the same
WO2009132208A1 (en) *	2008-04-24	2009-10-29	Evestra, Inc.	Oral contraceptive dosage forms comprising a progestogen dispersed in an enteric polymer and further comprising an estrogen
US8735374B2 (en) *	2009-07-31	2014-05-27	Intelgenx Corp.	Oral mucoadhesive dosage form
UY32836A (en)	2009-08-12	2011-03-31	Bayer Schering Pharma Ag	STABILIZED PARTICLES THAT INCLUDE 5-METHYL- (6S) -TETRAHYDROPHOLATE
US20110136815A1 (en)	2009-12-08	2011-06-09	Horst Zerbe	Solid oral film dosage forms and methods for making same
US10610528B2 (en)	2009-12-08	2020-04-07	Intelgenx Corp.	Solid oral film dosage forms and methods for making same
CA2796139A1 (en)	2010-04-15	2011-10-20	Bayer Intellectual Property Gmbh	Low-dosed solid oral dosage forms for hrt
KR20180018827A (en)	2010-04-15	2018-02-21	바이엘 인텔렉쳐 프로퍼티 게엠베하	Very low-dosed solid oral dosage forms for hrt
WO2012120365A1 (en)	2011-03-07	2012-09-13	Aurobindo Pharma Limited	Stable pharmaceutical composition comprising ethinyl estradiol
EP2383279A1 (en)	2011-07-19	2011-11-02	Pantarhei Bioscience B.V.	Process for the preparation of estetrol
US8586527B2 (en)	2011-10-20	2013-11-19	Jaipal Singh	Cerivastatin to treat pulmonary disorders
CN102512688A (en) *	2011-12-29	2012-06-27	上海新华联制药有限公司	Nilestriol-beta-cyclodextrin inclusion compound and preparation method thereof
RU2019104004A (en)	2012-01-23	2019-03-07	Сейдж Терапьютикс, Инк.	MEDICINAL FORMS OF NEUROACTIVE STEROIDS AND METHODS OF TREATING CNS DISORDERS
RU2494757C1 (en) *	2012-04-12	2013-10-10	Леонид Леонидович Клопотенко	Pharmaceutical composition containing enzyme deoxyribonuclease, alpha-fetoprotein and glycyrrhizic acid or salts thereof: ammonium or dipotassium or trisodium glycyrrhizinate
WO2013172969A1 (en)	2012-05-15	2013-11-21	The Uab Research Foundation	Methods and compositions for treating trauma-hemorrhage using estrogen and derivatives thereof
LT2887944T (en)	2012-08-21	2022-01-10	Sage Therapeutics, Inc.	ALOPREGNANOLONE FOR THE TREATMENT OF RESISTANT EPILEPTIC CONDITION
JOP20200195A1 (en)	2014-09-08	2017-06-16	Sage Therapeutics Inc	Neuroactive steroids and formulations, and their uses
HUE054551T2 (en)	2015-06-18	2021-09-28	Estetra Sprl	Orodispersible tablet containing estetrol
SMT201800232T1 (en)	2015-06-18	2018-07-17	Mithra Pharmaceuticals S A	Orodispersible dosage unit containing an estetrol component
MA44205B1 (en)	2015-06-18	2021-04-30	Estetra Sprl	Orodispersible tablet comprising estetrol
EP3310333B1 (en)	2015-06-18	2020-04-29	Estetra SPRL	Orodispersible dosage unit containing an estetrol component
MA45276A (en)	2015-06-18	2018-04-25	Sage Therapeutics Inc	NEUROACTIVE STEROID SOLUTIONS AND THEIR METHODS OF USE
RU2640081C1 (en) *	2016-07-11	2017-12-26	Общество с ограниченной ответственностью "ЛАЙФ САЙНСЕС ОХФК"	Pharmaceutical composition and medicinal product based on clathrate complex of n-carbamoylmethyl-4-phenyl-2-pyrrolidone, or 4-phenylpyracetam with cyclodextrin, method for production (versions)
KR102712911B1 (en)	2016-08-05	2024-10-04	에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼	Method for the management of dysmenorrhea and menstrual pain
JOP20200260A1 (en)	2018-04-19	2019-10-19	Estetra Sprl	Compounds and their uses for alleviating menopause-associated symptoms
TWI801561B (en)	2018-04-19	2023-05-11	比利時商依思特拉私人有限責任公司	Compounds and their uses for alleviating menopause-associated symptoms
EP3666260A1 (en) *	2018-12-13	2020-06-17	Laboratorios Leon Farma SA	Ethinyl estradiol-beta-cyclodextrin complex and process for preparing thereof
TWI893101B (en)	2020-04-16	2025-08-11	比利時商埃斯特拉有限責任公司	Contraceptive compositions with reduced adverse effects
CN114225050B (en) *	2022-01-29	2022-12-13	国家卫生健康委科学技术研究所	Preparation and application of ethinylestradiol cyclodextrin compound
CN116617157B (en) *	2023-05-25	2025-02-18	国家卫生健康委科学技术研究所	Method for preparing pH responsive ethinyl estradiol composite hydrogel

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4154820A (en) *	1976-02-23	1979-05-15	Akzona Incorporated	Compositions containing alkali metal sulfate salts of conjugated estrogens and antioxidants as stabilizers
DE2652761C2 (en)	1976-11-16	1985-11-21	Schering AG, 1000 Berlin und 4709 Bergkamen	15,16-methylene-spirolactones, processes for their preparation and pharmaceuticals containing them
JPS5527558A (en) *	1978-08-18	1980-02-27	Tokico Ltd	Gas spring
HU190356B (en)	1981-10-27	1986-08-28	Richter Gedeon Vegyeszeti Termekek Gyara Rt,Hu	Process for preparing steroid-gamma-cyclodextrin inclusion complexes with high water-solubility
US4383992A (en)	1982-02-08	1983-05-17	Lipari John M	Water-soluble steroid compounds
US4727064A (en) *	1984-04-25	1988-02-23	The United States Of America As Represented By The Department Of Health And Human Services	Pharmaceutical preparations containing cyclodextrin derivatives
US4596795A (en) *	1984-04-25	1986-06-24	The United States Of America As Represented By The Secretary, Dept. Of Health & Human Services	Administration of sex hormones in the form of hydrophilic cyclodextrin derivatives
US4727077A (en) *	1985-02-20	1988-02-23	Ishihara Sangyo Kaisha Ltd.	Benzoyl urea compounds, process for their production, and antitumorous compositions containing them
US4877774A (en)	1987-09-09	1989-10-31	The United States Of America As Represented By The Department Of Health And Human Services	Administration of steroid hormones
NL8801670A (en) *	1988-07-01	1990-02-01	Walter Adrianus Josephus Johan	PHARMACEUTICAL PREPARATION.
US5229370A (en)	1988-08-15	1993-07-20	Ammeraal Robert N	Water soluble branched beta cyclodextrin steroid complex
DE3916112A1 (en)	1989-05-16	1990-11-22	Schering Ag	DIHYDROSPIRORENONE AS AN ANTIANDROGEN
US4978532A (en) *	1989-08-11	1990-12-18	Pharmedic Co.	Dosage form for administration of dehydroepiandrosterone
JP3207212B2 (en)	1991-03-01	2001-09-10	久光製薬株式会社	Absorption promoter and external preparation containing the same
US5472954A (en) *	1992-07-14	1995-12-05	Cyclops H.F.	Cyclodextrin complexation
US5324718A (en) *	1992-07-14	1994-06-28	Thorsteinn Loftsson	Cyclodextrin/drug complexation
DE4426709A1 (en)	1994-07-20	1996-01-25	Schering Ag	Solid dosage forms containing steroidal sex hormones
JP4334616B2 (en) *	1994-09-22	2009-09-30	ナームローゼ・フエンノートチヤツプ・オルガノン	Method for producing a dosage unit by wet granulation
JP2920611B2 (en)	1995-12-11	1999-07-19	株式会社シーエーシー	Topical treatment for dermatitis
BR9710566A (en) *	1996-07-26	1999-08-17	American Home Prod	Monophysical contraceptive method and a kit comprising a combination of a progestin and estrogen
RO120603B1 (en) *	1996-08-22	2006-05-30	Research Triangle Pharmaceuticals Ltd.	Composition containing microparticles of water-insoluble substances and process for preparing the same
DE19652196A1 (en) *	1996-12-16	1998-06-18	Jenapharm Gmbh	Homogeneous pre-formulations containing steroids for the production of low-dose solid and semi-solid pharmaceutical preparations
DE19654609A1 (en) *	1996-12-20	1998-06-25	Schering Ag	Therapeutic progestogens for the treatment of premenstrual dysphoric disorder
DE19848303A1 (en) *	1998-10-14	2000-04-20	Schering Ag	Stable combination of 14,17-over-bridged steroid gestagen and cyclodextrin compound, useful for treating climacteric disorders or for contraception
EP1036510B1 (en) *	1999-03-18	2004-01-07	Bristol-Myers Squibb Company	Vitamin formulation for cardiovascular health
JP2000336032A (en) *	1999-05-26	2000-12-05	Kissei Pharmaceut Co Ltd	Sustained release oral medicinal composition containing piperazine acetamide
SI1214076T1 (en) *	1999-08-31	2004-06-30	Schering Aktiengesellschaft	Pharmaceutical combination of ethinylestradiol and drospirenone for use as a contraceptive
RU2275198C2 (en) *	2000-01-18	2006-04-27	Шеринг Акциенгезелльшафт	Drospyrenon for replacement hormonotherapy

2000
- 2000-12-20 EP EP00610135A patent/EP1216713A1/en not_active Withdrawn
2001
- 2001-12-20 CZ CZ2003-1985A patent/CZ305671B6/en not_active IP Right Cessation
- 2001-12-20 CA CA2432151A patent/CA2432151C/en not_active Expired - Lifetime
- 2001-12-20 AU AU1941802A patent/AU1941802A/en active Pending
- 2001-12-20 HU HU0302499A patent/HU230299B1/en unknown
- 2001-12-20 CN CNB018210880A patent/CN1268396C/en not_active Expired - Lifetime
- 2001-12-20 EP EP01271231A patent/EP1353700B1/en not_active Expired - Lifetime
- 2001-12-20 HR HR20030592A patent/HRP20030592B1/en not_active IP Right Cessation
- 2001-12-20 CA CA2756207A patent/CA2756207C/en not_active Expired - Lifetime
- 2001-12-20 AU AU2002219418A patent/AU2002219418B2/en not_active Expired
- 2001-12-20 ES ES01271231T patent/ES2249387T3/en not_active Expired - Lifetime
- 2001-12-20 RS YUP-512/03A patent/RS50362B/en unknown
- 2001-12-20 ES ES05077665.7T patent/ES2639537T3/en not_active Expired - Lifetime
- 2001-12-20 MX MXPA03005636A patent/MXPA03005636A/en active IP Right Grant
- 2001-12-20 KR KR1020097023221A patent/KR101275372B1/en not_active Expired - Lifetime
- 2001-12-20 DK DK05077665.7T patent/DK1632237T3/en active
- 2001-12-20 DE DE60115499T patent/DE60115499T2/en not_active Expired - Lifetime
- 2001-12-20 HR HRP20070198AA patent/HRP20070198B1/en not_active IP Right Cessation
- 2001-12-20 IL IL15643701A patent/IL156437A0/en active IP Right Grant
- 2001-12-20 NZ NZ526847A patent/NZ526847A/en not_active IP Right Cessation
- 2001-12-20 EA EA200600884A patent/EA011275B1/en not_active IP Right Cessation
- 2001-12-20 KR KR1020087028897A patent/KR20080108161A/en not_active Ceased
- 2001-12-20 EP EP05077665.7A patent/EP1632237B1/en not_active Expired - Lifetime
- 2001-12-20 SI SI200131065T patent/SI1632237T1/en unknown
- 2001-12-20 JP JP2002551012A patent/JP4782364B2/en not_active Expired - Lifetime
- 2001-12-20 RS RS20090299A patent/RS57801B1/en unknown
- 2001-12-20 AT AT01271231T patent/ATE311204T1/en active
- 2001-12-20 SI SI200130453T patent/SI1353700T1/en unknown
- 2001-12-20 EE EEP200300298A patent/EE05282B1/en unknown
- 2001-12-20 LT LTEP05077665.7T patent/LT1632237T/en unknown
- 2001-12-20 EA EA200300669A patent/EA007411B1/en not_active IP Right Cessation
- 2001-12-20 BR BR0116417-1 patent/BRPI0116417B8/en not_active IP Right Cessation
- 2001-12-20 ME MEP-381/08A patent/MEP38108A/en unknown
- 2001-12-20 HU HU1500492A patent/HU230745B1/en unknown
- 2001-12-20 WO PCT/IB2001/002605 patent/WO2002049675A1/en not_active Ceased
- 2001-12-20 KR KR10-2003-7008216A patent/KR20030070905A/en not_active Ceased
- 2001-12-20 CZ CZ2015-831A patent/CZ307876B6/en not_active IP Right Cessation
- 2001-12-20 SK SK914-2003A patent/SK287500B6/en not_active IP Right Cessation
- 2001-12-20 DK DK01271231T patent/DK1353700T3/en active
- 2001-12-20 US US10/022,845 patent/US6958326B2/en not_active Expired - Lifetime
2003
- 2003-06-12 IL IL156437A patent/IL156437A/en unknown
- 2003-06-19 NO NO20032805A patent/NO332726B1/en not_active IP Right Cessation
- 2003-07-18 BG BG108002A patent/BG66050B1/en unknown
2005
- 2005-04-11 US US11/102,681 patent/US7163931B2/en not_active Expired - Lifetime
2006
- 2006-02-28 CY CY20061100281T patent/CY1106071T1/en unknown
- 2006-10-04 AU AU2006225232A patent/AU2006225232B8/en not_active Expired
- 2006-12-04 US US11/607,919 patent/US7569557B2/en not_active Expired - Lifetime
2007
- 2007-12-19 IL IL188250A patent/IL188250A/en active IP Right Grant
2009
- 2009-02-05 JP JP2009025258A patent/JP5015976B2/en not_active Expired - Lifetime
2017
- 2017-09-20 CY CY20171100996T patent/CY1119806T1/en unknown

Publication	Publication Date	Title
AU2002219418A1 (en)	2002-09-05	Compositions of estrogen-cyclodextrin complexes
AU2002229065A1 (en)	2002-09-05	Compositions containing inclusion complexes
AU2001233691A1 (en)	2001-07-24	Antiperspirant compositions
AU781269C (en)	2006-11-30	Pharmaceutical compositions
AU2001282877A1 (en)	2002-01-21	Cosmetic compositions
AU2001234509A1 (en)	2001-07-31	Antimicrobial compositions
AU2001250420A1 (en)	2001-10-23	Pharmaceutical compositions
AU2001281887A1 (en)	2002-01-14	Enamel composition
AU2001274307A1 (en)	2002-01-02	Pharmaceutical compositions
AU2001265919A1 (en)	2001-11-20	Cosmetic compositions
AU2001282617A1 (en)	2002-04-29	Compositions for external preparations
AU2001268953A1 (en)	2002-02-05	Antimicrobial compositions
AU2001285790A1 (en)	2002-01-21	Antiperspirant compositions
AUPQ875700A0 (en)	2000-08-03	Combination compositions
AU2002214324A1 (en)	2002-08-08	Medicinal compositions
AU2001241098A1 (en)	2001-10-08	Composition
AU2001273919A1 (en)	2001-10-23	Pharmaceutical compositions
AU2681500A (en)	2000-09-14	Rapidly-soluble compositions
AU2001214419A1 (en)	2002-06-11	Fragrance compositions
AU2002210433A1 (en)	2002-02-05	Dental compositions
AU5085300A (en)	2001-03-05	Compositions
EP1438003B8 (en)	2008-10-08	Cosmetic compositions
AU2001256202A1 (en)	2001-10-03	Cosmetic compositions
AU2001275201A1 (en)	2001-12-11	Acne-treating composition
AU2001235764A1 (en)	2001-09-03	Compositions