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AU2001250420A1 - Pharmaceutical compositions - Google Patents

Pharmaceutical compositions

Info

Publication number
AU2001250420A1
AU2001250420A1 AU2001250420A AU5042001A AU2001250420A1 AU 2001250420 A1 AU2001250420 A1 AU 2001250420A1 AU 2001250420 A AU2001250420 A AU 2001250420A AU 5042001 A AU5042001 A AU 5042001A AU 2001250420 A1 AU2001250420 A1 AU 2001250420A1
Authority
AU
Australia
Prior art keywords
pharmaceutical compositions
pharmaceutical
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001250420A
Inventor
Michael Ambuhl
Barbara Haeberlin
Olivier Lambert
Barbara Luckel
Laurent Marchal
Armin Meinzer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of AU2001250420A1 publication Critical patent/AU2001250420A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Transplantation (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2001250420A 2000-04-10 2001-04-09 Pharmaceutical compositions Abandoned AU2001250420A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0008785.8A GB0008785D0 (en) 2000-04-10 2000-04-10 Organic compounds
GB0008785 2000-04-10
PCT/EP2001/004051 WO2001076561A2 (en) 2000-04-10 2001-04-09 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
AU2001250420A1 true AU2001250420A1 (en) 2001-10-23

Family

ID=9889585

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001250420A Abandoned AU2001250420A1 (en) 2000-04-10 2001-04-09 Pharmaceutical compositions

Country Status (12)

Country Link
US (3) US20030133984A1 (en)
EP (2) EP1767193A3 (en)
JP (1) JP2003530340A (en)
CN (2) CN100431600C (en)
AU (1) AU2001250420A1 (en)
BR (1) BR0109931A (en)
CA (1) CA2404368C (en)
FR (1) FR2807658A1 (en)
GB (1) GB0008785D0 (en)
IT (1) ITMI20010748A1 (en)
PE (1) PE20020225A1 (en)
WO (1) WO2001076561A2 (en)

Families Citing this family (38)

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DE10026698A1 (en) 2000-05-30 2001-12-06 Basf Ag Self-emulsifying active ingredient formulation and use of this formulation
US20040018228A1 (en) * 2000-11-06 2004-01-29 Afmedica, Inc. Compositions and methods for reducing scar tissue formation
AR033711A1 (en) * 2001-05-09 2004-01-07 Novartis Ag PHARMACEUTICAL COMPOSITIONS
GB0123400D0 (en) 2001-09-28 2001-11-21 Novartis Ag Organic compounds
JP4387639B2 (en) * 2002-07-16 2009-12-16 久光製薬株式会社 Transdermal absorption preparation
GB2391471B (en) * 2002-08-02 2005-05-04 Satishchandra Punambhai Patel Pharmaceutical compositions
GB0218996D0 (en) * 2002-08-14 2002-09-25 Novartis Ag Organic compounds
WO2004062643A1 (en) * 2003-01-14 2004-07-29 Lifecycle Pharma A/S Dry dispersions
US20040185068A1 (en) * 2003-03-18 2004-09-23 Zhi-Jian Yu Self-emulsifying compositions, methods of use and preparation
RU2345772C2 (en) * 2003-07-25 2009-02-10 Уайт Lyophilised compositions cci-779
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US20050059583A1 (en) 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
GB0504950D0 (en) * 2005-03-10 2005-04-20 Novartis Ag Organic compositions
US20070015693A1 (en) * 2005-07-13 2007-01-18 Allergan, Inc. Cyclosporin compositions
US7202209B2 (en) 2005-07-13 2007-04-10 Allergan, Inc. Cyclosporin compositions
US7276476B2 (en) * 2005-07-13 2007-10-02 Allergan, Inc. Cyclosporin compositions
US7297679B2 (en) * 2005-07-13 2007-11-20 Allergan, Inc. Cyclosporin compositions
US7288520B2 (en) 2005-07-13 2007-10-30 Allergan, Inc. Cyclosporin compositions
US20070015691A1 (en) 2005-07-13 2007-01-18 Allergan, Inc. Cyclosporin compositions
US7501393B2 (en) * 2005-07-27 2009-03-10 Allergan, Inc. Pharmaceutical compositions comprising cyclosporins
US7745400B2 (en) * 2005-10-14 2010-06-29 Gregg Feinerman Prevention and treatment of ocular side effects with a cyclosporin
US9839667B2 (en) 2005-10-14 2017-12-12 Allergan, Inc. Prevention and treatment of ocular side effects with a cyclosporin
EP1880715A1 (en) * 2006-07-19 2008-01-23 Abbott GmbH & Co. KG Pharmaceutically acceptable solubilizing composition and pharmaceutical dosage form containing same
KR102047634B1 (en) * 2007-03-07 2019-11-21 아브락시스 바이오사이언스, 엘엘씨 Nanoparticle comprising rapamycin and albumin as anticancer agent
CN101199836B (en) * 2007-11-07 2011-03-30 安徽省药物研究所 Stage releasing CsA solid tiny milk agent and tiny milk curing method thereof
CU23892B1 (en) * 2007-12-07 2013-04-19 Ct De Investigación Y Desarrollo De Medicamentos Cidem CYCLOSPORINE MICROENCAPSULATED PHARMACEUTICAL COMPOSITION A
ME01614B (en) * 2008-11-21 2014-09-20 Boehringer Ingelheim Int Pharmaceutical composition of a patent hcv inhibitor for oral administration
KR101685941B1 (en) 2009-07-07 2016-12-13 베링거 인겔하임 인터내셔날 게엠베하 Pharmaceutical composition for a hepatitis C viral protease inhibitor
WO2011034606A1 (en) * 2009-09-19 2011-03-24 Wu Nian Pharmaceutical compositions of rapamycin
WO2011139899A2 (en) 2010-05-03 2011-11-10 Teikoku Pharma Usa, Inc. Non-aqueous taxane pro-emulsion formulations and methods of making and using the same
JO3685B1 (en) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc Non-aqueous taxane nanodispersion formulations and methods of using the same
TW201503912A (en) * 2013-03-19 2015-02-01 Novartis Ag Pharmaceutical compositions comprising everolimus
US10576076B2 (en) 2015-05-20 2020-03-03 Novartis Ag Pharmaceutical combination of everolimus with dactolisib
ITUA20164228A1 (en) * 2016-06-09 2017-12-09 Labomar S R L Self-emulsifying and gastro-resistant fat matrix formulation and relative preparation method
CN110114070A (en) 2016-11-23 2019-08-09 诺华公司 Methods of enhancing immune response using everolimus, dactolisib, or both
WO2019157516A1 (en) 2018-02-12 2019-08-15 resTORbio, Inc. Combination therapies
WO2025153584A1 (en) * 2024-01-17 2025-07-24 Basf Se Solid self-emulsifying dosage form

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1274354A (en) 1956-03-10 1961-10-27 Surfactants obtained from triglycerides and polyethylene glycol
US3244592A (en) 1962-06-09 1966-04-05 Arai Tadashi Ascomycin and process for its production
ZA737247B (en) 1972-09-29 1975-04-30 Ayerst Mckenna & Harrison Rapamycin and process of preparation
EP0327280B1 (en) * 1988-01-29 1992-03-18 Sankyo Company Limited Cyclosporin compositions
GB2222770B (en) 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
ATE126803T1 (en) 1989-11-09 1995-09-15 Sandoz Ag TRICYCLIC COMPOUNDS CONTAINING HETEROATOMS.
MY110418A (en) 1990-07-02 1998-05-30 Novartis Ag Heteroatoms-containing tricyclic compounds.
PT98990A (en) 1990-09-19 1992-08-31 American Home Prod PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS OF RAPAMICIN
HU217808B (en) * 1990-11-06 2000-04-28 Nippon Shinyaku Co., Ltd. Process for producing liophylized preparative
US5120842A (en) 1991-04-01 1992-06-09 American Home Products Corporation Silyl ethers of rapamycin
US5100883A (en) 1991-04-08 1992-03-31 American Home Products Corporation Fluorinated esters of rapamycin
US5118678A (en) 1991-04-17 1992-06-02 American Home Products Corporation Carbamates of rapamycin
US5118677A (en) 1991-05-20 1992-06-02 American Home Products Corporation Amide esters of rapamycin
GB9113872D0 (en) 1991-06-27 1991-08-14 Sandoz Ag Improvements in or relating to organic compounds
US5151413A (en) 1991-11-06 1992-09-29 American Home Products Corporation Rapamycin acetals as immunosuppressant and antifungal agents
GB9125660D0 (en) 1991-12-03 1992-01-29 Smithkline Beecham Plc Novel compound
HUT66531A (en) 1992-05-07 1994-12-28 Sandoz Ag Heteroatoms-containing tricyclic compounds, pharmaceutical prepns contg. them and process for producing them
ZA935112B (en) 1992-07-17 1994-02-08 Smithkline Beecham Corp Rapamycin derivatives
US5234140A (en) 1992-07-28 1993-08-10 S. C. Johnson & Son, Inc. Re-useable aerosol container
US5256790A (en) 1992-08-13 1993-10-26 American Home Products Corporation 27-hydroxyrapamycin and derivatives thereof
GB9221220D0 (en) 1992-10-09 1992-11-25 Sandoz Ag Organic componds
US5258389A (en) 1992-11-09 1993-11-02 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynylrapamycin derivatives
JP4105761B2 (en) 1993-11-19 2008-06-25 アボット・ラボラトリーズ Semi-synthetic analog immunomodulator of rapamycin (macrolide)
KR0146671B1 (en) * 1994-02-25 1998-08-17 김충환 Cyclosporin-containing powder composition
WO1995025504A1 (en) * 1994-03-18 1995-09-28 Pharmavene, Inc. Emulsified drug delivery systems
RU2119351C1 (en) * 1994-06-01 1998-09-27 Юхан Корпорейшн Cyclosporin-containing immunosuppressive composition and a method of its preparing
MY129435A (en) 1994-10-26 2007-04-30 Novartis Ag Pharmaceutical microemulsion preconcentrates
US5716642A (en) * 1995-01-10 1998-02-10 Nano Systems L.L.C. Microprecipitation of nanoparticulate pharmaceutical agents using surface active material derived from similar pharmaceutical agents
DE19549852B4 (en) * 1995-11-29 2009-06-04 Novartis Ag Cyclosporin containing preparations
WO1999027946A1 (en) * 1997-12-02 1999-06-10 Chong Kun Dang Corp. Pharmaceutical composition comprising cyclosporin solid-state microemulsion
NZ328751A (en) * 1997-09-16 1999-01-28 Bernard Charles Sherman Solid medicament containing an anionic surfactant and cyclosporin
US20030216303A1 (en) * 1998-03-06 2003-11-20 Michael Ambuhl Emulsion preconcentrates containing cyclosporin or a macrolide
ID25908A (en) * 1998-03-06 2000-11-09 Novartis Ag EMULSION PRACTONCENTRATES CONTAINING CYCLOSPORINE OR MACROLIDES
DE19819273A1 (en) * 1998-04-30 1999-11-11 Pharmatec International S Giul Pharmaceutical ciclosporin formulation with improved biopharmaceutical properties, increased physical quality and stability as well as processes for its manufacture
KR100336090B1 (en) * 1998-06-27 2002-05-27 윤승원 Solid dispersed preparation of poorly water-soluble drug containing oil, fatty acid or mixture thereof
US6280770B1 (en) * 1998-08-13 2001-08-28 Cima Labs Inc. Microemulsions as solid dosage forms for oral administration
US6395300B1 (en) * 1999-05-27 2002-05-28 Acusphere, Inc. Porous drug matrices and methods of manufacture thereof
EP1227793A1 (en) * 1999-11-02 2002-08-07 Cipla Ltd. Cyclosporin formulation
GB0009773D0 (en) * 2000-04-19 2000-06-07 Univ Cardiff Particulate composition

Also Published As

Publication number Publication date
CN100431600C (en) 2008-11-12
US20060134203A1 (en) 2006-06-22
BR0109931A (en) 2003-05-27
EP1767193A3 (en) 2009-01-28
CN1231208C (en) 2005-12-14
WO2001076561A3 (en) 2002-02-21
FR2807658A1 (en) 2001-10-19
ITMI20010748A1 (en) 2002-10-06
EP1767193A2 (en) 2007-03-28
EP1272163A2 (en) 2003-01-08
ITMI20010748A0 (en) 2001-04-06
PE20020225A1 (en) 2002-04-15
CA2404368A1 (en) 2001-10-18
CA2404368C (en) 2011-02-01
CN1679916A (en) 2005-10-12
WO2001076561A2 (en) 2001-10-18
CN1422149A (en) 2003-06-04
JP2003530340A (en) 2003-10-14
GB0008785D0 (en) 2000-05-31
US20030133984A1 (en) 2003-07-17
US20100215734A1 (en) 2010-08-26

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