AU2002213925A1 - Use of glp-1 and flp-2 peptides for treatment of bone disorders - Google Patents
Use of glp-1 and flp-2 peptides for treatment of bone disordersInfo
- Publication number
- AU2002213925A1 AU2002213925A1 AU2002213925A AU1392502A AU2002213925A1 AU 2002213925 A1 AU2002213925 A1 AU 2002213925A1 AU 2002213925 A AU2002213925 A AU 2002213925A AU 1392502 A AU1392502 A AU 1392502A AU 2002213925 A1 AU2002213925 A1 AU 2002213925A1
- Authority
- AU
- Australia
- Prior art keywords
- treatment
- flp
- glp
- peptides
- bone disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Nutrition Science (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0022844.5 | 2000-09-18 | ||
| GB0022844A GB0022844D0 (en) | 2000-09-18 | 2000-09-18 | Use of GLP-1 and GLP-2 peptides |
| GB0029920.6 | 2000-12-07 | ||
| GB0029920A GB0029920D0 (en) | 2000-12-07 | 2000-12-07 | Use of glp-1 and glp-2 peptides |
| PCT/EP2001/010714 WO2002022151A2 (fr) | 2000-09-18 | 2001-09-17 | Utilisation de peptides glp-1 et glp-2 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2002213925A1 true AU2002213925A1 (en) | 2002-03-26 |
Family
ID=26245018
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002213925A Abandoned AU2002213925A1 (en) | 2000-09-18 | 2001-09-17 | Use of glp-1 and flp-2 peptides for treatment of bone disorders |
| AU2001287892A Abandoned AU2001287892A1 (en) | 2000-09-18 | 2001-09-18 | Use of glp -2 in combination with another therapeutic agent in bone-related and nutrition-related disorders |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001287892A Abandoned AU2001287892A1 (en) | 2000-09-18 | 2001-09-18 | Use of glp -2 in combination with another therapeutic agent in bone-related and nutrition-related disorders |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US6770620B2 (fr) |
| EP (3) | EP1970072A1 (fr) |
| JP (2) | JP5161412B2 (fr) |
| AT (2) | ATE396738T1 (fr) |
| AU (2) | AU2002213925A1 (fr) |
| CY (2) | CY1108263T1 (fr) |
| DE (2) | DE60134251D1 (fr) |
| DK (2) | DK1326630T3 (fr) |
| ES (2) | ES2310192T3 (fr) |
| PT (2) | PT1326630E (fr) |
| WO (2) | WO2002022151A2 (fr) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2686899B1 (fr) | 1992-01-31 | 1995-09-01 | Rhone Poulenc Rorer Sa | Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant. |
| ES2484966T3 (es) | 2000-04-12 | 2014-08-12 | Novozymes Biopharma Dk A/S | Proteínas de fusión de albúmina |
| US20070135345A1 (en) * | 2000-09-18 | 2007-06-14 | Henriksen Dennis B | Use of GLP-2 for the treatment or prevention, of bone-related disorders |
| US20080249016A1 (en) * | 2000-09-18 | 2008-10-09 | Sanos Bioscience A/S | Use of GLP-2 in a combination treatment for bone-related disorders |
| US7371721B2 (en) * | 2000-09-18 | 2008-05-13 | Sanos Bioscience A/S | Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes |
| PT1326630E (pt) * | 2000-09-18 | 2008-09-02 | Sanos Bioscience As | Utilização de péptidos glp-2 |
| US7186683B2 (en) * | 2000-09-18 | 2007-03-06 | Sanos Bioscience A/S | Use of GLP for the treatment, prevention, diagnosis, and prognosis of bone-related and nutrition-related disorders |
| RO120121B1 (ro) * | 2000-12-18 | 2005-09-30 | Elena Ionaşcu | Soluţie injectabilă, cu efect antiinflamator, procedeu de obţinere şi metodă de tratament a bolilor autoimune |
| CA2347330C (fr) * | 2001-05-10 | 2002-03-12 | Pharmaceutical Partners Of Canada Inc. | Preparation injectable liquide de pamidronate disodique |
| DE10135315A1 (de) * | 2001-07-19 | 2003-01-30 | Bayer Ag | Stents |
| WO2005003296A2 (fr) | 2003-01-22 | 2005-01-13 | Human Genome Sciences, Inc. | Proteines hybrides d'albumine |
| EP2277888A3 (fr) | 2001-12-21 | 2011-04-27 | Human Genome Sciences, Inc. | Protéine chimérique d'albumine et érythropoïetine |
| MXPA04011203A (es) * | 2002-05-17 | 2005-07-14 | Univ Duke | Metodo para tratar la obesidad. |
| US20050215552A1 (en) * | 2002-05-17 | 2005-09-29 | Gadde Kishore M | Method for treating obesity |
| WO2004084859A2 (fr) | 2003-03-21 | 2004-10-07 | Nastech Pharmaceutical Company Inc. | Formulations nasales de calcitonine contenant du chlorobutanol |
| JP2007525425A (ja) * | 2003-03-24 | 2007-09-06 | ノボ ノルディスク アクティーゼルスカブ | Glp−2誘導体 |
| EP1870096A3 (fr) * | 2003-04-29 | 2011-04-20 | Orexigen Therapeutics, Inc. | Compositions pour influencer la perte de poids |
| JP4343948B2 (ja) | 2003-04-29 | 2009-10-14 | オレキシジェン・セラピューティクス・インコーポレーテッド | 体重減少に影響を及ぼすための組成物 |
| JP4699374B2 (ja) | 2003-05-15 | 2011-06-08 | トラスティーズ オブ タフツ カレッジ | 安定なペプチド及びポリペプチドアナログ治療剤 |
| EP1734955A2 (fr) * | 2004-01-13 | 2006-12-27 | Duke University | Compositions anticonvulsives, medicament antipsychotique et leurs methodes d'utilisation permettant d'influer sur la perte de poids |
| US7713959B2 (en) * | 2004-01-13 | 2010-05-11 | Duke University | Compositions of an anticonvulsant and mirtazapine to prevent weight gain |
| US20050277579A1 (en) * | 2004-05-03 | 2005-12-15 | Ranga Krishnan | Compositions for affecting weight loss |
| AU2006242998B2 (en) * | 2005-05-04 | 2012-03-22 | Zealand Pharma A/S | Glucagon-like-peptide-2 (GLP-2) analogues |
| WO2006135660A2 (fr) * | 2005-06-10 | 2006-12-21 | University Of Chicago | Therapies faisant intervenir le recepteur beta de lymphotoxine |
| DK2135603T3 (da) * | 2005-11-22 | 2013-03-25 | Orexigen Therapeutics Inc | Sammensætninger og fremgangsmåder til øgning af insulinsensitivitet |
| WO2007089318A2 (fr) * | 2005-11-23 | 2007-08-09 | Orexigen Therapeutics, Inc. | Compositions et méthodes de réduction de la boulimie |
| WO2007133747A2 (fr) * | 2006-05-15 | 2007-11-22 | Wisconsin Alumni Research Foundation | ADMINISTRATION PULMONAIRE DE LA 1α,25-DIHYDROXYVITAMINE D3 AVEC COADMINISTRATION DE PARATHORMONE OU DE CALCITONINE |
| US8916195B2 (en) * | 2006-06-05 | 2014-12-23 | Orexigen Therapeutics, Inc. | Sustained release formulation of naltrexone |
| UA102506C2 (ru) | 2006-11-08 | 2013-07-25 | Зиланд Фарма А/С | Селективные аналоги глюкагоноподобного пептида-2 (glp-2) |
| TW200829235A (en) * | 2006-11-09 | 2008-07-16 | Orexigen Therapeutics Inc | Methods for administering weight loss medications |
| DE602007005402D1 (de) | 2006-11-09 | 2010-04-29 | Orexigen Therapeutics Inc | Mehrschichtige pharmazeutische formulierungen mit einer schnell auflösenden zwischenschicht |
| CA2682200C (fr) | 2007-03-19 | 2015-01-13 | Vita Sciences, Llc | Timbre transdermique et methode for d'administration de vitamine b12 |
| WO2009033746A2 (fr) * | 2007-09-11 | 2009-03-19 | Mondobiotech Laboratories Ag | Utilisation d'un peptide comme agent thérapeutique |
| CA2725930A1 (fr) | 2008-05-30 | 2009-12-30 | Orexigen Therapeutics, Inc. | Procedes pour traiter des pathologies des graisses viscerales |
| WO2010033240A2 (fr) | 2008-09-19 | 2010-03-25 | Nektar Therapeutics | Polymères à base de glucide pour administration de médicaments et leurs conjugués |
| WO2010042145A1 (fr) * | 2008-09-19 | 2010-04-15 | Nektar Therapeutics | Conjugués polymères de peptides de type glp-2 |
| DK2349324T3 (en) | 2008-10-17 | 2017-12-11 | Sanofi Aventis Deutschland | COMBINATION OF AN INSULIN AND A GLP-1 AGONIST |
| EA201290158A1 (ru) | 2009-09-23 | 2012-08-30 | Биокиер, Инк. | Композиция и способ лечения диабета |
| EP2311486A1 (fr) * | 2009-10-07 | 2011-04-20 | Nestec S.A. | GLP-2 en utilisation pour la récupération intestinale et musculaire |
| KR101836070B1 (ko) | 2009-11-13 | 2018-03-09 | 사노피-아벤티스 도이칠란트 게엠베하 | Glp-1 작용제, 인슐린 및 메티오닌을 포함하는 약제학적 조성물 |
| ES2965209T3 (es) | 2009-11-13 | 2024-04-11 | Sanofi Aventis Deutschland | Composición farmacéutica que comprende desPro36exendina-4(1-39)-Lys6-NH2 y metionina |
| EP2523557B1 (fr) | 2010-01-11 | 2019-09-25 | Nalpropion Pharmaceuticals, Inc. | Méthodes permettant de faire perdre du poids à des patients souffrant d'une dépression sévère |
| AU2011202239C1 (en) | 2010-05-19 | 2017-03-16 | Sanofi | Long-acting formulations of insulins |
| CN103179978A (zh) | 2010-08-30 | 2013-06-26 | 赛诺菲-安万特德国有限公司 | Ave0010用于制造供治疗2型糖尿病用的药物的用途 |
| US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
| EP2714089A4 (fr) * | 2011-05-24 | 2014-11-26 | Polyvalor Sec | Compositions et procédés pour l'administration efficace et sûre d'arnsi à l'aide de nanocomplexes spécifiques à base de chitosane |
| ES2550357T3 (es) | 2011-08-29 | 2015-11-06 | Sanofi-Aventis Deutschland Gmbh | Combinación farmacéutica para su uso en el control glucémico en pacientes de diabetes de tipo 2 |
| TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
| EA028929B1 (ru) | 2012-05-03 | 2018-01-31 | Зилэнд Фарма А/С | Аналоги глюкагоноподобного пептида-2 (glp-2) |
| EP4629257A3 (fr) | 2012-06-06 | 2025-12-10 | Nalpropion Pharmaceuticals LLC | Composition destinée à être utilisée dans une méthode de traitement du surpoids et de l'obésité chez des patients présentant un risque cardiovasculaire élevé |
| UA117480C2 (uk) | 2013-04-03 | 2018-08-10 | Санофі | Лікування цукрового діабету за допомогою складу інсуліну тривалої дії |
| WO2015016682A1 (fr) * | 2013-08-01 | 2015-02-05 | 경희대학교 산학협력단 | Composition pharmaceutique destinée a prévenir ou à traiter le diabète sucré, procédé de prévention ou de traitement du diabète sucré, et procédé de dépistage d'agent thérapeutique du diabète sucré |
| CN105637363B (zh) | 2013-08-01 | 2017-06-27 | 庆熙大学校产学协力团 | 预防或治疗糖尿病的药物组合物,预防或治疗糖尿病的方法,以及筛选糖尿病治疗药物的方法 |
| US8969371B1 (en) | 2013-12-06 | 2015-03-03 | Orexigen Therapeutics, Inc. | Compositions and methods for weight loss in at risk patient populations |
| HRP20230470T1 (hr) | 2014-12-12 | 2023-07-21 | Sanofi-Aventis Deutschland Gmbh | Formulacija fiksnog omjera inzulin glargin/liksisenatid |
| TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患治療 |
| TW201705975A (zh) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患之治療 |
| WO2016205701A1 (fr) | 2015-06-19 | 2016-12-22 | University Of Southern California | Système de plate-forme d'accès rapide au tractus entéral |
| US10631564B2 (en) | 2015-06-19 | 2020-04-28 | University Of Southern California | Enterically coated microparticle compositions and methods for modified nutrient delivery |
| WO2018009778A1 (fr) * | 2016-07-07 | 2018-01-11 | Baylor College Of Medicine | Combinaison de glp-1 et de glp-2 pour le traitement ou la prévention de maladies, troubles et syndromes métaboliques |
| US10774127B2 (en) | 2016-10-12 | 2020-09-15 | University Of Copenhagen | Peptide dual agonists of GIPR and GLP2R |
| JP6563614B1 (ja) | 2016-12-09 | 2019-08-21 | ジーランド・ファーマ・ア/エス | アシル化glp−1/glp−2二重アゴニスト |
| EP3881861B1 (fr) | 2017-06-16 | 2024-07-31 | Zealand Pharma A/S | Régimes posologiques pour l'administration d'analogues du peptide-2 de type glucagon (glp-2) |
| EP3694537A1 (fr) | 2017-10-12 | 2020-08-19 | University of Copenhagen | Polythérapie pour le traitement de maladies des os |
| EP3699187A1 (fr) * | 2019-02-21 | 2020-08-26 | Universite D'angers | Peptide ciblant les récepteurs du gip et du glp-2 pour le traitement de troubles osseux |
| US20210187077A1 (en) * | 2019-12-23 | 2021-06-24 | Idaho State University | GLP-1 Agonist Conjugates for Sustained Glycemic Control |
| JP2023508175A (ja) * | 2019-12-24 | 2023-03-01 | ハンミ ファーマシューティカル カンパニー リミテッド | Glp-2又はその結合体を含む、代謝性骨疾患の予防又は治療用薬学的組成物 |
| US20230355720A1 (en) * | 2020-09-25 | 2023-11-09 | Hanmi Pharm. Co., Ltd. | Pharmaceutical composition for preventing or treating bone diseases, comprising triple agonist or conjugate thereof having activity with respect to all of glucagon, glp-1 and glp receptors |
| US12303604B1 (en) | 2024-10-16 | 2025-05-20 | Currax Pharmaceuticals Llc | Pharmaceutical formulations comprising naltrexone and/or bupropion |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2583257B2 (ja) | 1986-05-05 | 1997-02-19 | ザ・ジェネラル・ホスピタル・コーポレーション | インシュリン向性ホルモン |
| JPH04504246A (ja) | 1989-03-20 | 1992-07-30 | ザ・ジェネラル・ホスピタル・コーポレーション | インシュリン刺激ホルモン |
| ES2113879T3 (es) | 1990-01-24 | 1998-05-16 | Douglas I Buckley | Analogos de glp-1 utiles para el tratamiento de diabetes. |
| NZ245015A (en) | 1991-11-05 | 1995-12-21 | Transkaryotic Therapies Inc | Delivery of human growth hormone through the administration of transfected cell lines encoding human growth hormone, which are physically protected from host immune response; the transfected cells and their production |
| US5512459A (en) | 1993-07-20 | 1996-04-30 | Bionebraska, Inc. | Enzymatic method for modification or recombinant polypeptides |
| US5789379A (en) | 1995-04-14 | 1998-08-04 | Allelix Biopharmaceutical Inc. | Glucagon-like peptide-2 analogs |
| US5834428A (en) | 1995-04-14 | 1998-11-10 | 1149336 Ontario Inc. | Glucagon-like peptide-2 and its therapeutic use |
| US6184201B1 (en) | 1995-04-14 | 2001-02-06 | Nps Allelix Corp. | Intestinotrophic glucagon-like peptide-2 analogs |
| US5990077A (en) * | 1995-04-14 | 1999-11-23 | 1149336 Ontario Inc. | Glucagon-like peptide-2 and its therapeutic use |
| BR9707807A (pt) * | 1996-03-01 | 1999-07-27 | Novo Nordisk As | Uso de uma composição farmacêutica composição farmacêutica processo de tratar doenças ou distúrbios associados com a regulação do apetite prejudicado e uso de um peptideo |
| US5912229A (en) | 1996-03-01 | 1999-06-15 | Novo Nordisk Als | Use of a pharmaceutical composition comprising an appetite-suppressing peptide |
| BRPI9708566B8 (pt) | 1996-04-12 | 2022-01-18 | Ontario Inc 1149336 | análogo de glp-2 de mamífero, e, composição farmacêutica. |
| DE69717629T2 (de) | 1996-07-05 | 2003-09-11 | Novo Nordisk A/S, Bagsvaerd | Verfahren zur produktion von polypeptiden |
| US5994500A (en) | 1996-07-19 | 1999-11-30 | 1149336 Ontario Inc. | Antagonists of intestinotrophic GLP-2 peptides |
| WO1998008872A1 (fr) | 1996-08-30 | 1998-03-05 | Novo Nordisk A/S | Derives de glp-2 |
| US6011155A (en) * | 1996-11-07 | 2000-01-04 | Novartis Ag | N-(substituted glycyl)-2-cyanopyrrolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV |
| AU5696298A (en) | 1996-12-06 | 1998-06-29 | Amgen, Inc. | Keratinocyte growth factors and uses thereof |
| US5952301A (en) | 1996-12-10 | 1999-09-14 | 1149336 Ontario Inc. | Compositions and methods for enhancing intestinal function |
| EP0946591B1 (fr) | 1996-12-13 | 2007-04-04 | Allelix Biopharmaceuticals Inc. | Recepteurs clones de peptides-2 semblables au glucagon |
| US6077949A (en) | 1996-12-13 | 2000-06-20 | Allelix Biopharmaceuticals, Inc. | Cloned glucagon-like peptide 2 receptors |
| DE69819488T2 (de) | 1997-05-16 | 2004-08-26 | 1149336 Ontario Inc., Toronto | Verwendung von glp-2 agonisten zur verbesserung der wirkung des oberen gastrointestinaltraktes |
| US6051557A (en) | 1997-05-16 | 2000-04-18 | 1149336 Ontario Inc. | Methods of enhancing functioning of the upper gastrointestinal tract |
| AU8671798A (en) | 1997-07-30 | 1999-02-22 | Betagene, Inc. | Methods and compositions relating to no-mediated cytotoxicity |
| WO1999014239A1 (fr) | 1997-09-12 | 1999-03-25 | Wolf Georg Forssmann | Composition pour le traitement du diabete sucre et de l'obesite |
| WO1999037793A1 (fr) | 1998-01-23 | 1999-07-29 | Novo Nordisk A/S | Procede servant a preparer des polypeptides souhaites dans de la levure |
| EP2433623A1 (fr) | 1998-02-02 | 2012-03-28 | Trustees Of Tufts College | Utilisation d'inhibiteurs de la dipeptidylpeptidase pour réguler le métabolisme du glucose |
| WO1999043361A1 (fr) | 1998-02-27 | 1999-09-02 | Novo Nordisk A/S | Derives de glp-2 avec teneur en structures en helices superieure a 25 %, formant des agregats de type micellaire partiellement structures |
| CA2321026A1 (fr) | 1998-03-09 | 1999-09-16 | Zealand Pharmaceuticals A/S | Conjugues peptidiques pharmacologiquement actifs ayant une tendance reduite a l'hydrolyse enzymatique |
| FR2777283B1 (fr) * | 1998-04-10 | 2000-11-24 | Adir | Nouveaux composes peptidiques analogues du glucagon-peptide- 1 (7-37), leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| WO1999058144A1 (fr) | 1998-05-11 | 1999-11-18 | 1149336 Ontario Inc. | Procedes d'amelioration du fonctionnement du gros intestin |
| WO2000010549A1 (fr) | 1998-08-21 | 2000-03-02 | Point Therapeutics, Inc. | Regulation de l'activite de substrat |
| US6193997B1 (en) | 1998-09-27 | 2001-02-27 | Generex Pharmaceuticals Inc. | Proteinic drug delivery system using membrane mimetics |
| DE69926007T2 (de) | 1998-10-07 | 2005-12-29 | Medical College Of Georgia Research Institute, Inc. | Glukose-abhängiges, insulinotropisches peptid für die verwendung als osteotropes hormon |
| WO2000028982A2 (fr) * | 1998-11-19 | 2000-05-25 | The Board Of Trustees For The University Of Arkansas | Renforcement de la structure osseuse a l'aide de diphosphonates selectionnes |
| CZ295889B6 (cs) * | 1998-12-07 | 2005-11-16 | Societe De Conseils De Recherches Et D'application | Analogy GLP-1, mající arginin na pozicích 26 a 34, jejich použití a farmaceutické prostředky je obsahující |
| CA2352573C (fr) * | 1998-12-07 | 2012-04-10 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R | Analogues glp-1 |
| CO5150173A1 (es) | 1998-12-10 | 2002-04-29 | Novartis Ag | Compuestos n-(glicilo sustituido)-2-cianopirrolidinas inhibidores de peptidasa de dipeptidilo-iv (dpp-iv) los cuales son efectivos en el tratamiento de condiciones mediadas por la inhibicion de dpp-iv |
| US6271200B1 (en) | 1998-12-21 | 2001-08-07 | Generex Pharmaceuticals Inc. | Proteinic drug delivery system using aerosolized membrane-mimetic amphiphiles |
| WO2000042026A1 (fr) | 1999-01-15 | 2000-07-20 | Novo Nordisk A/S | Agonistes non peptidiques de glp-1 |
| GB9905416D0 (en) | 1999-03-09 | 1999-05-05 | Allelix Biopharma | Small molecules having GLP-2 like activity |
| US6110949A (en) * | 1999-06-24 | 2000-08-29 | Novartis Ag | N-(substituted glycyl)-4-cyanothiazolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV |
| EP1076066A1 (fr) | 1999-07-12 | 2001-02-14 | Zealand Pharmaceuticals A/S | Peptides abaissant le taux de glucose sanguin |
| WO2001041779A2 (fr) | 1999-12-08 | 2001-06-14 | 1149336 Ontario Inc. | Traitement relatif a la chimiotherapie |
| CA2380423A1 (fr) * | 2000-05-17 | 2001-11-22 | Bionebraska, Inc. | Preparations pharmaceutiques peptidiques |
| ATE346093T1 (de) * | 2000-06-16 | 2006-12-15 | Lilly Co Eli | Analoge des glucagon ähnlichen peptid-1 |
| WO2002010195A2 (fr) * | 2000-08-02 | 2002-02-07 | Theratechnologies Inc. | Peptides biologiques modifies presentant une activite renforcee |
| PT1326630E (pt) * | 2000-09-18 | 2008-09-02 | Sanos Bioscience As | Utilização de péptidos glp-2 |
| WO2002066062A2 (fr) | 2001-02-01 | 2002-08-29 | Drucker Daniel J | Renforcement de l'activite de glp-2 |
-
2001
- 2001-09-17 PT PT01982302T patent/PT1326630E/pt unknown
- 2001-09-17 ES ES01982302T patent/ES2310192T3/es not_active Expired - Lifetime
- 2001-09-17 US US09/954,304 patent/US6770620B2/en not_active Expired - Fee Related
- 2001-09-17 EP EP08156283A patent/EP1970072A1/fr not_active Withdrawn
- 2001-09-17 EP EP01982302A patent/EP1326630B1/fr not_active Expired - Lifetime
- 2001-09-17 JP JP2002526401A patent/JP5161412B2/ja not_active Expired - Fee Related
- 2001-09-17 AU AU2002213925A patent/AU2002213925A1/en not_active Abandoned
- 2001-09-17 AT AT01982302T patent/ATE396738T1/de active
- 2001-09-17 DE DE60134251T patent/DE60134251D1/de not_active Expired - Lifetime
- 2001-09-17 WO PCT/EP2001/010714 patent/WO2002022151A2/fr not_active Ceased
- 2001-09-17 DK DK01982302T patent/DK1326630T3/da active
- 2001-09-18 PT PT01967517T patent/PT1414486E/pt unknown
- 2001-09-18 JP JP2002528284A patent/JP5189723B2/ja not_active Expired - Fee Related
- 2001-09-18 DE DE60142084T patent/DE60142084D1/de not_active Expired - Lifetime
- 2001-09-18 AT AT01967517T patent/ATE466592T1/de active
- 2001-09-18 EP EP01967517A patent/EP1414486B1/fr not_active Expired - Lifetime
- 2001-09-18 DK DK01967517.2T patent/DK1414486T3/da active
- 2001-09-18 WO PCT/GB2001/004178 patent/WO2002024214A2/fr not_active Ceased
- 2001-09-18 AU AU2001287892A patent/AU2001287892A1/en not_active Abandoned
- 2001-09-18 ES ES01967517T patent/ES2345874T3/es not_active Expired - Lifetime
-
2003
- 2003-03-18 US US10/391,460 patent/US6943151B2/en not_active Expired - Fee Related
-
2008
- 2008-08-13 CY CY20081100866T patent/CY1108263T1/el unknown
-
2010
- 2010-07-30 CY CY20101100721T patent/CY1110721T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP5161412B2 (ja) | 2013-03-13 |
| DE60142084D1 (de) | 2010-06-17 |
| EP1970072A1 (fr) | 2008-09-17 |
| JP5189723B2 (ja) | 2013-04-24 |
| EP1414486A2 (fr) | 2004-05-06 |
| EP1326630B1 (fr) | 2008-05-28 |
| ATE466592T1 (de) | 2010-05-15 |
| PT1414486E (pt) | 2010-07-21 |
| US20040082507A1 (en) | 2004-04-29 |
| DE60134251D1 (de) | 2008-07-10 |
| PT1326630E (pt) | 2008-09-02 |
| JP2004524268A (ja) | 2004-08-12 |
| WO2002024214A3 (fr) | 2004-02-19 |
| EP1326630A2 (fr) | 2003-07-16 |
| CY1108263T1 (el) | 2014-02-12 |
| WO2002022151A2 (fr) | 2002-03-21 |
| US20020037836A1 (en) | 2002-03-28 |
| WO2002024214A2 (fr) | 2002-03-28 |
| JP2004508410A (ja) | 2004-03-18 |
| US6943151B2 (en) | 2005-09-13 |
| EP1414486B1 (fr) | 2010-05-05 |
| ES2310192T3 (es) | 2009-01-01 |
| ATE396738T1 (de) | 2008-06-15 |
| CY1110721T1 (el) | 2015-06-10 |
| WO2002022151A3 (fr) | 2003-03-13 |
| DK1414486T3 (da) | 2010-08-30 |
| DK1326630T3 (da) | 2008-09-15 |
| US6770620B2 (en) | 2004-08-03 |
| AU2001287892A1 (en) | 2002-04-02 |
| ES2345874T3 (es) | 2010-10-05 |
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