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AU2001281782A1 - Integrated optical waveguides for microfluidic analysis systems - Google Patents

Integrated optical waveguides for microfluidic analysis systems

Info

Publication number
AU2001281782A1
AU2001281782A1 AU2001281782A AU8178201A AU2001281782A1 AU 2001281782 A1 AU2001281782 A1 AU 2001281782A1 AU 2001281782 A AU2001281782 A AU 2001281782A AU 8178201 A AU8178201 A AU 8178201A AU 2001281782 A1 AU2001281782 A1 AU 2001281782A1
Authority
AU
Australia
Prior art keywords
optical waveguides
integrated optical
analysis systems
microfluidic analysis
microfluidic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001281782A
Other languages
English (en)
Inventor
Thomas Greve
Gunter Hauke
Matthias Johnck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of AU2001281782A1 publication Critical patent/AU2001281782A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44791—Microapparatus
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/10—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
    • G02B6/12—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
    • G02B6/13—Integrated optical circuits characterised by the manufacturing method
    • G02B6/138—Integrated optical circuits characterised by the manufacturing method by using polymerisation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0825—Test strips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/10—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
    • G02B6/12—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
    • G02B2006/12035—Materials
    • G02B2006/12069—Organic material
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/10—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
    • G02B6/12—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
    • G02B2006/12035—Materials
    • G02B2006/12069—Organic material
    • G02B2006/12071—PMMA
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/10—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
    • G02B6/12—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
    • G02B2006/12083—Constructional arrangements
    • G02B2006/12121—Laser
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/10—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
    • G02B6/12—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
    • G02B2006/12083—Constructional arrangements
    • G02B2006/12123—Diode
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/10—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
    • G02B6/12—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
    • G02B2006/12133—Functions
    • G02B2006/12138—Sensor

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Electrochemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Optics & Photonics (AREA)
  • Optical Integrated Circuits (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
AU2001281782A 2000-06-17 2001-05-22 Integrated optical waveguides for microfluidic analysis systems Abandoned AU2001281782A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10029946 2000-06-17
DE10029946A DE10029946A1 (de) 2000-06-17 2000-06-17 Integrierte optische Wellenleiter für mikrofluidische Analysensysteme
PCT/EP2001/005843 WO2001098759A1 (fr) 2000-06-17 2001-05-22 Guides d'ondes optiques integres pour systemes d'analyse microfluidiques

Publications (1)

Publication Number Publication Date
AU2001281782A1 true AU2001281782A1 (en) 2002-01-02

Family

ID=7646134

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001281782A Abandoned AU2001281782A1 (en) 2000-06-17 2001-05-22 Integrated optical waveguides for microfluidic analysis systems

Country Status (6)

Country Link
US (1) US20030161572A1 (fr)
EP (1) EP1292822A1 (fr)
JP (1) JP2004501372A (fr)
AU (1) AU2001281782A1 (fr)
DE (1) DE10029946A1 (fr)
WO (1) WO2001098759A1 (fr)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002069016A2 (fr) 2001-02-28 2002-09-06 Lightwave Microsystems Corporation Commande microfluidique pour commutateurs de guides d'ondes optiques, attenuateurs variables et autres dispositifs optiques
US7016560B2 (en) 2001-02-28 2006-03-21 Lightwave Microsystems Corporation Microfluidic control for waveguide optical switches, variable attenuators, and other optical devices
GB2383127B (en) 2001-12-12 2004-10-20 Proimmune Ltd Device and method for investigating analytes in liquid suspension or solution
JP2003227950A (ja) * 2002-02-01 2003-08-15 Omron Corp 光学素子およびその製造方法
JP3880930B2 (ja) * 2002-07-26 2007-02-14 株式会社エンプラス プレートの接着部構造
JP3880931B2 (ja) * 2002-08-23 2007-02-14 株式会社エンプラス プレートの組立構造
US7226564B2 (en) * 2002-07-26 2007-06-05 Enplas Corporation Plate assembly
JP4014500B2 (ja) * 2002-12-20 2007-11-28 住友ベークライト株式会社 マイクロチップ基板の接合方法及びマイクロチップ
WO2005003769A1 (fr) * 2003-07-04 2005-01-13 Kubota Corporation Biopuce
EP1703925A1 (fr) * 2003-11-27 2006-09-27 Commissariat A L'Energie Atomique Microdispositif de diagnostic et de therapie in vivo
DE102004015906B4 (de) * 2004-03-31 2006-02-16 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Mikrofluidische Vorrichtung für die optische Analyse
US7155082B2 (en) * 2004-04-12 2006-12-26 Colorado School Of Mines Switchable microfluidic optical waveguides
DE102004033440A1 (de) * 2004-07-08 2006-02-02 NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen Mikrostrukturierte Vorrichtung und Verfahren zu ihrer Herstellung
WO2006015360A1 (fr) * 2004-07-30 2006-02-09 President And Fellows Of Harvard College Guides d'ondes fluides et utilisations
WO2006086551A2 (fr) * 2005-02-08 2006-08-17 President And Fellows Of Harvard College Lasers microfluidiques
DE112006000642B4 (de) * 2005-03-18 2014-03-13 Nanyang Technological University Mikrofluidischer Sensor zur Messung der Grenzflächenspannung und Verfahren zum Messen der Grenzflächenspannung
US8351741B2 (en) 2005-10-03 2013-01-08 Creatv Microtech, Inc. Sensitive emission light gathering and flow through detection system
US9976192B2 (en) 2006-03-10 2018-05-22 Ldip, Llc Waveguide-based detection system with scanning light source
US9528939B2 (en) 2006-03-10 2016-12-27 Indx Lifecare, Inc. Waveguide-based optical scanning systems
US8399101B2 (en) * 2006-09-19 2013-03-19 E I Du Pont De Nemours And Company Toughened poly(hydroxyalkanoic acid) compositions
KR100799267B1 (ko) * 2006-10-13 2008-01-29 이화여자대학교 산학협력단 Ｎｏａ로 제조한 마이크로 또는 나노 유체칩 및 이를사용하여 제조한 바이오분석 플랫폼
CN101583864A (zh) * 2006-12-21 2009-11-18 皇家飞利浦电子股份有限公司 线栅波导
DE102007021544A1 (de) * 2007-05-08 2008-11-13 Siemens Ag Messeinheit und Verfahren zur optischen Untersuchung einer Flüssigkeit auf eine Analytkonzentration
US20100032582A1 (en) * 2008-08-07 2010-02-11 General Electric Company Fluorescence detection system and method
DE102008038993B4 (de) * 2008-08-13 2011-06-22 Karlsruher Institut für Technologie, 76131 Optisches Element und Verfahren zu seiner Herstellung
DE102009025072A1 (de) 2009-06-16 2010-12-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zum Erzeugen eines Bereiches mit erhöhtem Brechungsindex und ein Substrat mit örtlich variablem Brechungsindex
DE102009025073A1 (de) * 2009-06-16 2010-12-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Optischer Sensor
DE102012103628B4 (de) 2012-04-25 2020-12-31 Avl Emission Test Systems Gmbh Vorrichtung zur Bestimmung der Konzentration zumindest eines Gases in einem Probengasstrom
CN112557301A (zh) 2012-07-25 2021-03-26 赛拉诺斯知识产权有限责任公司 生物学样本的图像分析及测量
US9513224B2 (en) 2013-02-18 2016-12-06 Theranos, Inc. Image analysis and measurement of biological samples
US9113570B2 (en) * 2012-10-31 2015-08-18 Tyco Electronics Services Gmbh Planar electronic device having a magnetic component
US10036709B2 (en) * 2014-05-20 2018-07-31 Roche Diabetes Care, Inc. BG meter illuminated test strip
WO2016019026A1 (fr) * 2014-07-29 2016-02-04 Indx Lifecare, Inc. Puces de détection à base de guide d'onde partiellement encapsulées, systèmes et procédés d'utilisation
US11181479B2 (en) 2015-02-27 2021-11-23 Ldip, Llc Waveguide-based detection system with scanning light source
WO2017031303A1 (fr) 2015-08-18 2017-02-23 University Of Cincinnati Détecteur optique et son procédé d'utilisation
US10768105B1 (en) 2016-07-29 2020-09-08 Labrador Diagnostics Llc Image analysis and measurement of biological samples
US10974241B2 (en) 2017-03-30 2021-04-13 TE Connectivity Services Gmbh Fluid sensing system
DE102018202591A1 (de) * 2018-02-21 2019-08-22 Robert Bosch Gmbh Optisches System sowie ein Verfahren zur Herstellung eines optischen Systems
DE102018118110B4 (de) * 2018-07-26 2023-01-05 OSRAM Opto Semiconductors Gesellschaft mit beschränkter Haftung Sensorvorrichtung und verfahren zur herstellung einer sensorvorrichtung
US20220143606A1 (en) * 2019-07-26 2022-05-12 Hewlett-Packard Development Company, L.P. Microfluidic devices

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6176962B1 (en) * 1990-02-28 2001-01-23 Aclara Biosciences, Inc. Methods for fabricating enclosed microchannel structures
US6054034A (en) * 1990-02-28 2000-04-25 Aclara Biosciences, Inc. Acrylic microchannels and their use in electrophoretic applications
US5858188A (en) * 1990-02-28 1999-01-12 Aclara Biosciences, Inc. Acrylic microchannels and their use in electrophoretic applications
US5046800A (en) * 1990-10-09 1991-09-10 At&T Bell Laboratories Article comprising a passive optical waveguide
US5313545A (en) * 1993-02-19 1994-05-17 Motorola, Inc. Molded waveguide with a unitary cladding region and method of making
SE9304145D0 (sv) * 1993-12-10 1993-12-10 Pharmacia Lkb Biotech Sätt att tillverka hålrumsstrukturer
US5644395A (en) * 1995-07-14 1997-07-01 Regents Of The University Of California Miniaturized flow injection analysis system
DE19642088A1 (de) * 1996-10-12 1998-04-16 Bosch Gmbh Robert Verfahren zur Herstellung eines mikrostrukturierten Körpers, eines Gußrahmens und eines integriert-optischen Bauteils
US6788862B2 (en) * 2002-05-14 2004-09-07 Corning, Inc. Microstructured optical waveguide having large optical nonlinearity

Also Published As

Publication number Publication date
US20030161572A1 (en) 2003-08-28
WO2001098759A1 (fr) 2001-12-27
DE10029946A1 (de) 2001-12-20
JP2004501372A (ja) 2004-01-15
EP1292822A1 (fr) 2003-03-19

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