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AU2001281052A1 - Transgenic mice containing ubiquitin protein ligase e3 gene disruptions - Google Patents

Transgenic mice containing ubiquitin protein ligase e3 gene disruptions

Info

Publication number
AU2001281052A1
AU2001281052A1 AU2001281052A AU8105201A AU2001281052A1 AU 2001281052 A1 AU2001281052 A1 AU 2001281052A1 AU 2001281052 A AU2001281052 A AU 2001281052A AU 8105201 A AU8105201 A AU 8105201A AU 2001281052 A1 AU2001281052 A1 AU 2001281052A1
Authority
AU
Australia
Prior art keywords
transgenic mice
protein ligase
ubiquitin protein
mice containing
gene disruptions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001281052A
Inventor
Michael W. Leviten
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deltagen Inc
Original Assignee
Deltagen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deltagen Inc filed Critical Deltagen Inc
Publication of AU2001281052A1 publication Critical patent/AU2001281052A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y603/00—Ligases forming carbon-nitrogen bonds (6.3)
    • C12Y603/02—Acid—amino-acid ligases (peptide synthases)(6.3.2)
    • C12Y603/02019—Ubiquitin-protein ligase (6.3.2.19), i.e. ubiquitin-conjugating enzyme
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2001281052A 2000-08-07 2001-08-03 Transgenic mice containing ubiquitin protein ligase e3 gene disruptions Abandoned AU2001281052A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22346100P 2000-08-07 2000-08-07
US60/223,461 2000-08-07
PCT/US2001/024441 WO2002011672A2 (en) 2000-08-07 2001-08-03 Transgenic mice containing ubiquitin protein ligase e3 gene disruptions

Publications (1)

Publication Number Publication Date
AU2001281052A1 true AU2001281052A1 (en) 2002-02-18

Family

ID=22836594

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001281052A Abandoned AU2001281052A1 (en) 2000-08-07 2001-08-03 Transgenic mice containing ubiquitin protein ligase e3 gene disruptions

Country Status (2)

Country Link
AU (1) AU2001281052A1 (en)
WO (1) WO2002011672A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1436409A2 (en) * 2001-09-07 2004-07-14 Massachusetts Institute Of Technology Lanthanide binding tags

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001619A (en) * 1995-10-04 1999-12-14 Cold Spring Harbor Laboratory Ubiquitin ligases, and uses related thereto
US5976849A (en) * 1998-02-05 1999-11-02 Zeneca Limited Human E3 ubiquitin protein ligase
AU767507B2 (en) * 1998-08-28 2003-11-13 New York University Novel ubiquitin ligases as therapeutic targets
GB9826276D0 (en) * 1998-12-01 1999-01-20 Univ Leeds Therapeutic agents for use in degenerative disorders
ATE499445T1 (en) * 1998-12-10 2011-03-15 Signal Pharm Llc HUMAN UBIQUITIN LIGASE E3. USE FOR MODULATION OF NF-KAPPA B

Also Published As

Publication number Publication date
WO2002011672A2 (en) 2002-02-14
WO2002011672A3 (en) 2003-07-10

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