[go: up one dir, main page]

AU2001241146A1 - Glucopyranosyloxy benzylbenzene derivatives, medicinal compositions containing the same and intermediates for the preparation of the derivatives - Google Patents

Glucopyranosyloxy benzylbenzene derivatives, medicinal compositions containing the same and intermediates for the preparation of the derivatives

Info

Publication number
AU2001241146A1
AU2001241146A1 AU2001241146A AU2001241146A AU2001241146A1 AU 2001241146 A1 AU2001241146 A1 AU 2001241146A1 AU 2001241146 A AU2001241146 A AU 2001241146A AU 2001241146 A AU2001241146 A AU 2001241146A AU 2001241146 A1 AU2001241146 A1 AU 2001241146A1
Authority
AU
Australia
Prior art keywords
derivatives
glucopyranosyloxy
intermediates
preparation
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2001241146A
Other versions
AU2001241146B2 (en
AU2001241146B8 (en
Inventor
Hideki Fujikura
Nobuhiko Fushimi
Masahiro Hiratochi
Masayuki Isaji
Kenji Katsuno
Toshihiro Nishimura
Kazuya Tatani
Yoshiki Tokutake
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kissei Pharmaceutical Co Ltd
Original Assignee
Kissei Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kissei Pharmaceutical Co Ltd filed Critical Kissei Pharmaceutical Co Ltd
Priority claimed from PCT/JP2001/002041 external-priority patent/WO2001068660A1/en
Publication of AU2001241146A1 publication Critical patent/AU2001241146A1/en
Publication of AU2001241146B2 publication Critical patent/AU2001241146B2/en
Application granted granted Critical
Publication of AU2001241146B8 publication Critical patent/AU2001241146B8/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

AU2001241146A 2000-03-17 2001-03-15 Glucopyranosyloxy benzylbenzene derivatives, medicinal compositions containing the same and intermediates for the preparation of the derivatives Ceased AU2001241146B8 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000077304 2000-03-17
JP2000-77304 2000-03-17
PCT/JP2001/002041 WO2001068660A1 (en) 2000-03-17 2001-03-15 Glucopyranosyloxy benzylbenzene derivatives, medicinal compositions containing the same and intermediates for the preparation of the derivatives

Publications (3)

Publication Number Publication Date
AU2001241146A1 true AU2001241146A1 (en) 2001-12-06
AU2001241146B2 AU2001241146B2 (en) 2006-06-29
AU2001241146B8 AU2001241146B8 (en) 2006-07-27

Family

ID=18594892

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2001241146A Ceased AU2001241146B8 (en) 2000-03-17 2001-03-15 Glucopyranosyloxy benzylbenzene derivatives, medicinal compositions containing the same and intermediates for the preparation of the derivatives
AU4114601A Pending AU4114601A (en) 2000-03-17 2001-03-15 Glucopyranosyloxy benzylbenzene derivatives, medicinal compositions containing the same and intermediates for the preparation of the derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU4114601A Pending AU4114601A (en) 2000-03-17 2001-03-15 Glucopyranosyloxy benzylbenzene derivatives, medicinal compositions containing the same and intermediates for the preparation of the derivatives

Country Status (27)

Country Link
US (3) US7465712B2 (en)
EP (1) EP1270584B1 (en)
JP (1) JP3773450B2 (en)
KR (1) KR100660738B1 (en)
CN (1) CN1177857C (en)
AT (1) ATE312114T1 (en)
AU (2) AU2001241146B8 (en)
BG (1) BG65867B1 (en)
BR (1) BR0109323A (en)
CA (1) CA2402609C (en)
CZ (1) CZ20023023A3 (en)
DE (1) DE60115623T2 (en)
DK (1) DK1270584T3 (en)
ES (1) ES2254376T3 (en)
HU (1) HUP0300057A3 (en)
IL (2) IL151757A0 (en)
MX (1) MXPA02009034A (en)
NO (1) NO324249B1 (en)
NZ (1) NZ521369A (en)
PL (1) PL205605B1 (en)
RU (1) RU2254340C2 (en)
SK (1) SK287183B6 (en)
TR (1) TR200202200T2 (en)
TW (1) TWI293305B (en)
UA (1) UA72586C2 (en)
WO (1) WO2001068660A1 (en)
ZA (1) ZA200207418B (en)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1020944C (en) 1990-01-30 1993-05-26 阿图尔-费希尔股份公司费希尔厂 Fastening element
US6683056B2 (en) * 2000-03-30 2004-01-27 Bristol-Myers Squibb Company O-aryl glucoside SGLT2 inhibitors and method
AU2001290257B2 (en) * 2000-09-29 2007-08-30 Kissei Pharmaceutical Co., Ltd Glucopyranosyloxybenzylbenzene derivatives and medicinal compositions containing the same
CA2429833A1 (en) * 2000-11-30 2002-06-06 Kissei Pharmaceutical Co., Ltd. Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and intermediates in the production thereof
TWI255817B (en) * 2001-02-14 2006-06-01 Kissei Pharmaceutical Glucopyranosyloxybenzylbenzene derivatives and medicinal use thereof
JPWO2003011880A1 (en) * 2001-07-31 2004-11-18 キッセイ薬品工業株式会社 Glucopyranosyloxybenzylbenzene derivatives, pharmaceutical compositions containing the same, pharmaceutical uses thereof and intermediates for the production thereof
PL210710B1 (en) * 2002-03-22 2012-02-29 Kissei Pharmaceutical Crystals of glucopyranosyloxybenzyl benzene derivative
US7956041B2 (en) * 2002-04-26 2011-06-07 Ajinomoto Co., Inc. Prophylactic and therapeutic agent of diabetes mellitus
HRP20040814A2 (en) * 2002-08-09 2005-06-30 Taisho Pharmaceutical Co. Aryl 5-thio-?-d-glucopyranoside derivatives and therapeutic agents for diabetes containing the same
JP4651934B2 (en) * 2002-12-04 2011-03-16 キッセイ薬品工業株式会社 Benzylphenol derivative, pharmaceutical composition containing it, and pharmaceutical use thereof
DE10258008B4 (en) * 2002-12-12 2006-02-02 Sanofi-Aventis Deutschland Gmbh Heterocyclic fluoroglycoside derivatives, medicaments containing these compounds and methods of making these medicaments
DE10258007B4 (en) 2002-12-12 2006-02-09 Sanofi-Aventis Deutschland Gmbh Aromatic fluoroglycoside derivatives, medicaments containing these compounds and methods for the preparation of these medicaments
US7094763B2 (en) 2003-08-01 2006-08-22 Janssen Pharaceutica, N.V. Substituted fused heterocyclic C-glycosides
AR048282A1 (en) 2003-08-01 2006-04-19 Janssen Pharmaceutica Nv INDOL- O - SUBSTITUTED GLUCOSIDS
RS20060320A (en) 2003-08-01 2008-08-07 Janssen Pharmaceutica N.V., Substituted indazole-o-glucosides
UA86042C2 (en) 2003-08-01 2009-03-25 Янссен Фармацевтика Н.В. Substituted indazole-o-glucosides
PT1651658E (en) 2003-08-01 2013-03-07 Mitsubishi Tanabe Pharma Corp Novel compounds having inhibitory activity against sodium-dependant transporter
US7094764B2 (en) 2003-08-01 2006-08-22 Janssen Pharmaceutica N.V. Substituted benzimidazole-, Benztriazole-, and benzimidazolone-O-glucosides
US8785403B2 (en) 2003-08-01 2014-07-22 Mitsubishi Tanabe Pharma Corporation Glucopyranoside compound
US7375090B2 (en) 2003-08-26 2008-05-20 Boehringer Ingelheim International Gmbh Glucopyranosyloxy-pyrazoles, pharmaceutical compositions containing these compounds, the use thereof and processed for the preparation thereof
US7371732B2 (en) * 2003-12-22 2008-05-13 Boehringer Ingelheim International Gmbh Glucopyranosyloxy-substituted aromatic compounds, medicaments containing such compounds, their use and process for their manufacture
DK1730131T3 (en) * 2004-03-16 2012-08-13 Boehringer Ingelheim Int Glucopyranosyl-substituted benzene derivatives, drug containing these compounds, their use and methods for their preparation
CA2560005A1 (en) * 2004-03-31 2005-10-13 Kissei Pharmaceutical Co., Ltd. Phenol derivative, medicinal composition containing the same, and medicinal use thereof
WO2006009149A1 (en) 2004-07-21 2006-01-26 Kissei Pharmaceutical Co., Ltd. Progression inhibitor for disease attributed to abnormal accumulation of liver fat
TW200606129A (en) 2004-07-26 2006-02-16 Chugai Pharmaceutical Co Ltd Novel cyclohexane derivative, its prodrug, its salt and diabetic therapeutic agent containing the same
EP1813611B1 (en) 2004-11-18 2014-10-01 Kissei Pharmaceutical Co., Ltd. 1-substituted-3- beta-d-glycopyranosylated nitrogenous hetero- cyclic compounds and medicines containing the same
TW200637869A (en) 2005-01-28 2006-11-01 Chugai Pharmaceutical Co Ltd The spiroketal derivatives and the use as therapeutical agent for diabetes of the same
CN101111508B (en) * 2005-01-28 2011-03-30 中外制药株式会社 Spiroketal derivatives and their use as therapeutic drugs for diabetes
AR053329A1 (en) * 2005-01-31 2007-05-02 Tanabe Seiyaku Co INDOL DERIVATIVES USEFUL AS INHIBITORS OF GLUCOSE CONVEYORS DEPENDENT ON SODIUM (SGLT)
JP5073948B2 (en) * 2005-01-31 2012-11-14 田辺三菱製薬株式会社 Pharmaceutical composition
MY147375A (en) 2005-01-31 2012-11-30 Mitsubishi Tanabe Pharma Corp Indole derivatives
US7772191B2 (en) * 2005-05-10 2010-08-10 Boehringer Ingelheim International Gmbh Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein
PE20080251A1 (en) 2006-05-04 2008-04-25 Boehringer Ingelheim Int USES OF DPP IV INHIBITORS
BRPI0711949A2 (en) 2006-05-19 2012-01-17 Taisho Pharmaceutical Co., Ltd. c-phenyl glycitol compound
DE102006028862A1 (en) 2006-06-23 2007-12-27 Merck Patent Gmbh 3-amino-imidazo [1,2-a] pyridine
AU2007266078B2 (en) 2006-06-29 2011-12-15 Taisho Pharmaceutical Co., Ltd. C-phenyl 1-thioglucitol compound
TWI418556B (en) * 2006-07-27 2013-12-11 Mitsubishi Tanabe Pharma Corp Indole derivatives
TWI432446B (en) 2006-07-27 2014-04-01 Chugai Pharmaceutical Co Ltd Fused ring spiroketal derivative and use thereof as anti-diabetic drug
TWI403516B (en) 2006-07-27 2013-08-01 Chugai Pharmaceutical Co Ltd To replace spirocyclic alcohol derivatives, and its use as a therapeutic agent for diabetes
TW200817424A (en) 2006-08-04 2008-04-16 Daiichi Sankyo Co Ltd Benzylphenyl glucopyranoside derivatives
TWI499414B (en) 2006-09-29 2015-09-11 Lexicon Pharmaceuticals Inc Inhibitors of sodium glucose co-transporter 2 and methods of their use
CA2664920A1 (en) * 2006-10-13 2008-04-17 Chugai Seiyaku Kabushiki Kaisha Thioglucose spiroketal derivative and use thereof as therapeutic agent for diabetes
EP2099791B1 (en) 2006-12-04 2012-11-21 Janssen Pharmaceutica, N.V. Thienyl-containing glycopyranosyl derivatives as antidiabetics
UY30730A1 (en) 2006-12-04 2008-07-03 Mitsubishi Tanabe Pharma Corp CRYSTAL FORM OF HEMIHYDRATE 1- (B (BETA) -D-GLUCOPYRANOSIL) -4-METHYL-3- [5- (4-FLUOROPHENYL) -2-TIENYLMETHYL] BENZENE
MY157365A (en) 2006-12-06 2016-05-31 Smithkline Beecham Corp Chemical compounds and uses
US20100069460A1 (en) 2006-12-14 2010-03-18 Taisho Pharmaceutical Co., Ltd. 1-phenyl 1-thio-d-glucitol derivative
DE102007008420A1 (en) 2007-02-21 2008-08-28 Merck Patent Gmbh benzimidazole derivatives
US7846945B2 (en) * 2007-03-08 2010-12-07 Lexicon Pharmaceuticals, Inc. Piperdine-based inhibitors of sodium glucose co-transporter 2 and methods of their use
TW200904454A (en) 2007-03-22 2009-02-01 Bristol Myers Squibb Co Methods for treating obesity employing an SGLT2 inhibitor and compositions thereof
DK2183263T3 (en) 2007-07-26 2012-01-30 Lexicon Pharmaceuticals Inc Methods and Compounds Useful for Preparation of Sodium Glucose Co-Transporter-2 Inhibitors
NO2200606T3 (en) 2007-09-10 2018-03-24
DE102007048716A1 (en) 2007-10-11 2009-04-23 Merck Patent Gmbh Imidazo [1,2-a] pyrimidine derivatives
CL2008003653A1 (en) 2008-01-17 2010-03-05 Mitsubishi Tanabe Pharma Corp Use of a glucopyranosyl-derived sglt inhibitor and a selected dppiv inhibitor to treat diabetes; and pharmaceutical composition.
WO2009096503A1 (en) * 2008-01-31 2009-08-06 Daiichi Sankyo Company, Limited Benzyl phenyl glucopyranoside derivative
DE102008017590A1 (en) 2008-04-07 2009-10-08 Merck Patent Gmbh Glucopyranosidderivate
CA2730734C (en) 2008-07-15 2017-04-25 Theracos, Inc. Deuterated 2,3,4-trihydroxy-tetrahydropyranyl-benzylbenzene compounds having sodium glucose cotransporter inhibitory activity
BRPI0918841B8 (en) * 2008-08-28 2021-05-25 Pfizer dioxa-bicyclo[3.2.1]octane-2,3,4-triol derivatives, their crystals, pharmaceutical compositions and uses
US9056850B2 (en) 2008-10-17 2015-06-16 Janssen Pharmaceutica N.V. Process for the preparation of compounds useful as inhibitors of SGLT
CN101445528B (en) * 2008-12-25 2011-06-15 天津药物研究院 Sulpho-glucosan derivative and preparation method and application thereof
AU2010212865A1 (en) 2009-02-13 2011-07-21 Boehringer Ingelheim International Gmbh SGLT-2 inhibitor for treating type 1 diabetes mellitus, type 2 diabetes mellitus, impaired glucose tolerance or hyperglycemia
US20110009347A1 (en) * 2009-07-08 2011-01-13 Yin Liang Combination therapy for the treatment of diabetes
JP5658751B2 (en) 2009-07-10 2015-01-28 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプＪａｎｓｓｅｎ Ｐｈａｒｍａｃｅｕｔｉｃａ Ｎａａｍｌｏｚｅ Ｖｅｎｎｏｏｔｓｃｈａｐ Crystallization method for 1- (β-D-glucopyranosyl) -4-methyl-3- [5- (4-fluorophenyl) -2-thienylmethyl] benzene
BR112012007085B8 (en) * 2009-09-30 2021-05-25 Boehringer Ingelheim Int processes for the preparation of glycopyranosyl substituted benzyl-benzene derivatives
HUE031375T2 (en) 2009-10-14 2017-07-28 Janssen Pharmaceutica Nv A method for preparing compounds useful as SGLT2 inhibitors
US8163704B2 (en) 2009-10-20 2012-04-24 Novartis Ag Glycoside derivatives and uses thereof
EP2491050A2 (en) 2009-10-20 2012-08-29 Novartis AG Glycoside derivative and uses thereof
SI2496583T1 (en) 2009-11-02 2015-02-27 Pfizer Inc. Dioxa-bicycloš3.2.1ćoctane-2,3,4-triol derivatives
WO2011107494A1 (en) 2010-03-03 2011-09-09 Sanofi Novel aromatic glycoside derivatives, medicaments containing said compounds, and the use thereof
SG185525A1 (en) 2010-05-11 2012-12-28 Janssen Pharmaceutica Nv Pharmaceutical formulations comprising 1 - (beta-d-glucopyranosyl) - 2 -thienylmethylbenzene derivatives as inhibitors of sglt
US9522162B2 (en) 2011-03-23 2016-12-20 University Of Utah Research Foundation Methods for treating or preventing urological inflammation
KR101913587B1 (en) 2011-04-13 2018-10-31 얀센 파마슈티카 엔.브이. Process for the preparation of compounds useful as inhibitors of sglt2
CN103619862A (en) 2011-04-14 2014-03-05 诺瓦提斯公司 Glycoside derivatives and uses thereof
US8614195B2 (en) 2011-04-14 2013-12-24 Novartis Ag Glycoside derivatives and uses thereof
TWI542596B (en) 2011-05-09 2016-07-21 健生藥品公司 (2S,3R,4R,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxyl L-proline and citric acid cocrystals of methyl)tetrahydro-2H-piperan-3,4,5-triol
US9192617B2 (en) 2012-03-20 2015-11-24 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
EP2774619B1 (en) 2013-03-04 2016-05-18 BioActive Food GmbH Composition for the treatment of hyperglycaemic diseases
HK1213818A1 (en) 2013-04-05 2016-07-15 勃林格殷格翰国际有限公司 Therapeutic uses of empagliflozin
US11813275B2 (en) 2013-04-05 2023-11-14 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
PT2981271T (en) 2013-04-05 2019-02-19 Boehringer Ingelheim Int Therapeutic uses of empagliflozin
CA2812519A1 (en) 2013-04-05 2014-10-05 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
EA033286B1 (en) 2013-04-18 2019-09-30 Бёрингер Ингельхайм Интернациональ Гмбх Method of treating or delaying the progression of chronic kidney disease
EP2944311A1 (en) 2014-05-16 2015-11-18 BioActive Food GmbH Combination of biologically active substances for treating hyperglycemic diseases
CN105939157B (en) * 2015-03-03 2019-08-06 卡西欧计算机株式会社 Level conversion circuit and projection device
US20170071970A1 (en) 2015-09-15 2017-03-16 Janssen Pharmaceutica Nv Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders
US20180125813A1 (en) 2016-11-10 2018-05-10 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
CN113980071B (en) * 2021-11-26 2023-08-22 重庆大学 Salidroside derivatives and their applications
CN114933619B (en) * 2022-05-18 2024-03-01 上海科利生物医药有限公司 A class of thioglycoside gliflozin analogues and their preparation methods and applications

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2549476B1 (en) * 1983-07-20 1986-04-25 Rech Ind BENZYL-PHENYL-OSIDES, PROCESS FOR PREPARATION AND THERAPEUTIC USE
DE3718638A1 (en) * 1987-06-04 1988-12-22 Thomae Gmbh Dr K NEW PHENYLETHANOLAMINE, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
HU229581B1 (en) 1999-08-31 2014-02-28 Kissei Pharmaceutical Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermediates in the production thereof
US6683056B2 (en) * 2000-03-30 2004-01-27 Bristol-Myers Squibb Company O-aryl glucoside SGLT2 inhibitors and method

Similar Documents

Publication Publication Date Title
AU2001241146A1 (en) Glucopyranosyloxy benzylbenzene derivatives, medicinal compositions containing the same and intermediates for the preparation of the derivatives
HUP0300057A3 (en) Glucopyranosyloxy benzylbenzene derivatives, pharmaceutical compositions containing the same and intermediates for the preparation of the derivatives
AU4949800A (en) 2-arylpurine-9-acetamide derivatives, process for the preparation thereof, medicinal compositions containing the same and intermediates of the derivatives
AU2001237526A1 (en) Pharmaceutical compositions containing 3-amino-azetidine derivatives, novel derivatives and preparation thereof
AU2001237525A1 (en) Azetidine derivatives, preparation thereof and pharmaceutical compositions containing same
AU2001290257A2 (en) Glucopyranosyloxybenzylbenzene derivatives and medicinal compositions containing the same
DZ3311A1 (en) Pharmaceutical compositions containing 3-amino-azetidine derivatives, novel derivatives and preparation thereof
AU2003246810A1 (en) Diphenylpyridine derivatives, the preparation thereof, and pharmaceutical compositions containing said derivatives
AU2002363236A1 (en) Compounds, pharmaceutical compositions and methods of use therefor
HUP0201278A3 (en) Pyrazolecarboamide derivative, its preparation, pharmaceutical compositions containing it and its intermediates
AU2002223127A1 (en) Glucopyranosyloxybenzyl benzene derivatives, medicinal compositions containing the same and intermediates in the production thereof
AU2001235691A1 (en) Use of paullone derivatives for making medicines
HUP0400200A3 (en) Pharmaceutical formulation for the efficient administration of apomorphine, 6ar-(-)-n-propyl-norapomorphine and their derivatives and pro-drugs thereof
HUP0401747A3 (en) Piridazine derivatives of hydrazono-malonitriles, their use, process for preparation of the compounds and pharmaceutical compositions containing the compounds
AU2001262733A1 (en) Medicinal compositions containing propenone derivatives
HUP0204563A3 (en) Process for preparation of 3,3-diarylpropylamine derivatives and their intermediates and their use for preparation of pharmaceutical compositions
AU2001292331A2 (en) 5-amidino-2-hydroxybenzenesulfonamide derivatives, pharmaceutical compositions containing the same and intermediates for their preparation
AU2001292331A1 (en) 5-amidino-2-hydroxybenzenesulfonamide derivatives, pharmaceutical compositions containing the same and intermediates for their preparation
HUP0401654A3 (en) Heterokondensated pyrimidine derivatives, their intermediates, preparations of the compounds and pharmaceutical compositions containing them
AU2001252711A1 (en) Aqueous-prodrug compound comprising moiety of paclitxel or derivatives thereof, method of preparing same and pharmaceutical composition comprising same
AU3560601A (en) Novel isoquinoline derivatives, preparation method and pharmaceutical compositions containing them
AU4913399A (en) Thioazepinone derivatives, preparation method and intermediates therefor, use asmedicines and pharmaceutical compositions containing same
IL154986A0 (en) Triazolo-epothilone derivatives, pharmaceutical compositions containing the same and methods for the preparation thereof
AU2001277728A1 (en) Biphenylcarboxamidoisoindoline compounds, processes for the preparation of the same and intermediates for the synthesis thereof
AU2001274022A1 (en) Use of substituted 1-amino-5-phenylpentane-3-ol and/or 1-amino-6-phenylhexane-3-ol compounds as medicaments