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AU3560601A - Novel isoquinoline derivatives, preparation method and pharmaceutical compositions containing them - Google Patents

Novel isoquinoline derivatives, preparation method and pharmaceutical compositions containing them

Info

Publication number
AU3560601A
AU3560601A AU35606/01A AU3560601A AU3560601A AU 3560601 A AU3560601 A AU 3560601A AU 35606/01 A AU35606/01 A AU 35606/01A AU 3560601 A AU3560601 A AU 3560601A AU 3560601 A AU3560601 A AU 3560601A
Authority
AU
Australia
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
isoquinoline derivatives
novel isoquinoline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU35606/01A
Inventor
Inmaculada Andreu Ros
Ghanem Atassi
Almudena Bermejo Del Castillo
Nuria Cabedo Escrig
Daniel-Henri Caignard
Diego Cortes Martinez
Alain Pierre
Pierre Renard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Les Laboratoires Servier SAS
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Publication of AU3560601A publication Critical patent/AU3560601A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU35606/01A 2000-01-28 2001-01-26 Novel isoquinoline derivatives, preparation method and pharmaceutical compositions containing them Abandoned AU3560601A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES200000185A ES2172376B1 (en) 2000-01-28 2000-01-28 NEW DERIVATIVES OF ISOQUINOLEINS, ITS PREPARATION PROCEDURE AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
ES200000185 2000-01-28
PCT/FR2001/000245 WO2001055117A1 (en) 2000-01-28 2001-01-26 Novel isoquinoline derivatives, preparation method and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
AU3560601A true AU3560601A (en) 2001-08-07

Family

ID=8492086

Family Applications (1)

Application Number Title Priority Date Filing Date
AU35606/01A Abandoned AU3560601A (en) 2000-01-28 2001-01-26 Novel isoquinoline derivatives, preparation method and pharmaceutical compositions containing them

Country Status (3)

Country Link
AU (1) AU3560601A (en)
ES (1) ES2172376B1 (en)
WO (1) WO2001055117A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ535366A (en) 2002-03-13 2007-07-27 Univ Tennessee Res Foundation Substituted tetrahydroisoquinoline compounds, methods of making, and their use
FR2853649B1 (en) * 2003-04-09 2006-07-14 Servier Lab NOVEL ISOQUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
US7067529B2 (en) * 2003-05-19 2006-06-27 Hoffmann-La Roche Inc. Glutamine fructose-y-phosphate amidotransferase (GFAT) inhibitors
EP1675845A2 (en) * 2003-10-16 2006-07-05 F. Hoffmann-La Roche Ag Glutamine fructose-6-phosphate amidotransferase (gfat) inhibitors
NZ575620A (en) 2006-09-20 2010-11-26 Mallinckrodt Inc Preparation of substituted morphinan-6-ones and salts and intermediates thereof
MX2009005919A (en) * 2006-12-11 2009-06-16 Mallinckrodt Inc Preparation of 3,4-dihydroisoquinolines from an acid and an amine.
AU2008223328B2 (en) 2007-03-06 2012-10-11 SpecGx LLC Process for the preparation of quaternary N-alkyl morphinan alkaloid salts
US9040726B2 (en) 2007-03-06 2015-05-26 Mallinckrodt Llc Process for the preparation of quaternary N-alkyl morphinan alkaloid salts
EP2285780B1 (en) 2008-05-27 2015-08-26 Mallinckrodt LLC Processes and compounds for the preparation of normorphinans
US9458109B2 (en) 2008-09-03 2016-10-04 Mallinckrodt Llc Substituted berbines and processes for their synthesis
WO2021192726A1 (en) * 2020-03-24 2021-09-30 学校法人東京医科大学 Choline uptake inhibitor, apoptosis inducer, anticancer drug, and use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9721964D0 (en) * 1997-10-16 1997-12-17 Pfizer Ltd Isoquinolines

Also Published As

Publication number Publication date
WO2001055117A1 (en) 2001-08-02
ES2172376A1 (en) 2002-09-16
ES2172376B1 (en) 2003-11-16

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase