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AU1036600A - Method for the production of quercetin and isoquercetin derivatives - Google Patents

Method for the production of quercetin and isoquercetin derivatives

Info

Publication number
AU1036600A
AU1036600A AU10366/00A AU1036600A AU1036600A AU 1036600 A AU1036600 A AU 1036600A AU 10366/00 A AU10366/00 A AU 10366/00A AU 1036600 A AU1036600 A AU 1036600A AU 1036600 A AU1036600 A AU 1036600A
Authority
AU
Australia
Prior art keywords
quercetin
production
isoquercetin
derivatives
isoquercetin derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU10366/00A
Inventor
Herwig Buchholz
Ralf Rosskopf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19850282A external-priority patent/DE19850282A1/en
Priority claimed from DE19850570A external-priority patent/DE19850570A1/en
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of AU1036600A publication Critical patent/AU1036600A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/16Emollients or protectives, e.g. against radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26Acyclic or carbocyclic radicals, substituted by hetero rings
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/06Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Neurosurgery (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
AU10366/00A 1998-10-30 1999-10-13 Method for the production of quercetin and isoquercetin derivatives Abandoned AU1036600A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19850282A DE19850282A1 (en) 1998-10-30 1998-10-30 Preparation of new or known tris-hydroxyalkyl quercetin and isoquercetin derivatives by enzymatic cleavage of rutin derivatives, used e.g. as nutritional supplements, cosmetic UV filters or cardiovascular drugs
DE19850282 1998-10-30
DE19850570A DE19850570A1 (en) 1998-11-02 1998-11-02 Production of new or known tri-O-hydroxyalkyl quercetin or isoquercetin derivatives, e.g. useful as food supplements, comprises enzymatic hydrolysis of tri-O-hydroxyalkyl rutin derivatives in an aqueous medium
DE19850570 1998-11-02
PCT/EP1999/007685 WO2000026399A2 (en) 1998-10-30 1999-10-13 Method for the production of quercetin and isoquercetin derivatives

Publications (1)

Publication Number Publication Date
AU1036600A true AU1036600A (en) 2000-05-22

Family

ID=26049877

Family Applications (1)

Application Number Title Priority Date Filing Date
AU10366/00A Abandoned AU1036600A (en) 1998-10-30 1999-10-13 Method for the production of quercetin and isoquercetin derivatives

Country Status (8)

Country Link
EP (1) EP1124980A2 (en)
JP (1) JP2002528132A (en)
KR (1) KR20010080347A (en)
CN (1) CN1325452A (en)
AU (1) AU1036600A (en)
BR (1) BR9914811A (en)
CA (1) CA2348728A1 (en)
WO (1) WO2000026399A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19923715A1 (en) * 1999-05-22 2000-11-23 Beiersdorf Ag Cosmetic or dermatological sunscreen preparations containing flavone derivatives and / or flavanone derivatives, in particular flavonoids and s-triazine, and the use of UV filter substances having the structural motif of s-triazine for stabilizing flavone derivatives and / or flavanone derivatives, in particular flavonoids
DE19923712A1 (en) * 1999-05-22 2000-11-23 Beiersdorf Ag Active substance combination of sulfonated UV filter substances and flavone derivatives and / or flavanone derivatives, in particular flavonoids, and cosmetic preparations containing such active substance combinations
DE19923713A1 (en) * 1999-05-22 2000-11-23 Beiersdorf Ag Cosmetic or dermatological sunscreen preparations containing flavone derivatives and / or flavanone derivatives, in particular flavonoids and benzotriazole, and the use of UV filter substances having the structural motif of benzotriazole for stabilizing flavone derivatives and / or flavanone derivatives, in particular flavonoids
DE19927425A1 (en) 1999-06-16 2000-12-21 Merck Patent Gmbh Obtaining isoquercetin from bioflavanoid pastes
EP1127572A3 (en) * 2000-02-25 2003-05-02 Basf Aktiengesellschaft Use of flavones for treating cycloxygenase-2 mediated diseases
DE10232595A1 (en) * 2002-07-18 2004-02-05 Merck Patent Gmbh Light stabilizers
DE102005015447A1 (en) * 2005-04-05 2006-10-12 Merck Patent Gmbh Process for the cleavage of rutinosides
CN101985439B (en) * 2010-11-18 2012-05-09 桂林市三棱生物制品有限公司 Process for separating and extracting 98% quercetin from aerial parts of pubescent holly root
JP2016013075A (en) * 2014-07-01 2016-01-28 イビデン株式会社 Quercetin-containing extract
CN105412074A (en) * 2015-12-24 2016-03-23 厦门大学 Application of quercetin in preparation of medicine for preventing and treating diseases related to ApoE protein level
US10639294B2 (en) 2018-10-02 2020-05-05 Janssen Pharmaceutica Nv Pharmaceutical compositions comprising a hydroxyethylquercetin glucuronide metabolite
US11304968B2 (en) 2018-11-16 2022-04-19 Janssen Pharmaceutica Nv Pharmaceutical compositions comprising a hydroxyethylquercetin glucuronide

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5072M (en) * 1965-10-25 1967-05-16
US4603046A (en) * 1985-08-23 1986-07-29 Charles Of The Ritz Group Ltd. Improved sunscreen or sunblock composition
JPH01308476A (en) * 1988-06-06 1989-12-13 Showa Denko Kk Ultraviolet ray absorber
JPH03255013A (en) * 1990-03-01 1991-11-13 San Ei Chem Ind Ltd Cosmetic
JP3477628B2 (en) * 1995-06-19 2003-12-10 アサヒビール株式会社 Polyphenol preparation obtained from hop bract and its manufacturing method

Also Published As

Publication number Publication date
KR20010080347A (en) 2001-08-22
JP2002528132A (en) 2002-09-03
CN1325452A (en) 2001-12-05
WO2000026399A2 (en) 2000-05-11
WO2000026399A3 (en) 2000-08-10
BR9914811A (en) 2001-07-03
EP1124980A2 (en) 2001-08-22
CA2348728A1 (en) 2000-05-11

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase