AU7414300A - Method for the production of substituted pyrimidine derivatives - Google Patents
Method for the production of substituted pyrimidine derivativesInfo
- Publication number
- AU7414300A AU7414300A AU74143/00A AU7414300A AU7414300A AU 7414300 A AU7414300 A AU 7414300A AU 74143/00 A AU74143/00 A AU 74143/00A AU 7414300 A AU7414300 A AU 7414300A AU 7414300 A AU7414300 A AU 7414300A
- Authority
- AU
- Australia
- Prior art keywords
- production
- pyrimidine derivatives
- substituted pyrimidine
- substituted
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 title 1
- 150000003230 pyrimidines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/31—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19942809A DE19942809A1 (en) | 1999-09-08 | 1999-09-08 | Process for the preparation of substituted pyrimidine derivatives |
| DE19942809 | 1999-09-08 | ||
| PCT/EP2000/008362 WO2001017998A2 (en) | 1999-09-08 | 2000-08-28 | Method for the production of substituted pyrimidine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU7414300A true AU7414300A (en) | 2001-04-10 |
Family
ID=7921171
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU74143/00A Abandoned AU7414300A (en) | 1999-09-08 | 2000-08-28 | Method for the production of substituted pyrimidine derivatives |
Country Status (3)
| Country | Link |
|---|---|
| AU (1) | AU7414300A (en) |
| DE (1) | DE19942809A1 (en) |
| WO (1) | WO2001017998A2 (en) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10122894A1 (en) * | 2001-05-11 | 2002-11-14 | Bayer Ag | New pyrazolo(3,4-b)pyridin-3-yl)-5-pyrimidinyl sulfonates, are soluble guanyl cyclase stimulants useful e.g. for treating cardiovascular, thromboembolic or central nervous system diseases |
| DE102007028319A1 (en) | 2007-06-20 | 2008-12-24 | Bayer Healthcare Ag | Substituted oxazolidinones and their use |
| DE102007028406A1 (en) | 2007-06-20 | 2008-12-24 | Bayer Healthcare Ag | Substituted oxazolidinones and their use |
| DE102007028407A1 (en) | 2007-06-20 | 2008-12-24 | Bayer Healthcare Ag | Substituted oxazolidinones and their use |
| DE102007028320A1 (en) | 2007-06-20 | 2008-12-24 | Bayer Healthcare Ag | Substituted oxazolidinones and their use |
| EP2138178A1 (en) | 2008-06-28 | 2009-12-30 | Bayer Schering Pharma Aktiengesellschaft | Oxazolidninones for the treatment fo chronic obstructive pulmonary disease (COPD) and/or asthma |
| US20130178475A1 (en) | 2010-03-17 | 2013-07-11 | Ironwood Pharmaceuticals, Inc. | sGC STIMULATORS |
| DK2588465T3 (en) | 2010-06-30 | 2017-05-01 | Ironwood Pharmaceuticals Inc | SGC stimulators |
| RU2582679C2 (en) | 2010-11-09 | 2016-04-27 | Айронвуд Фармасьютикалз, Инк. | sGC STIMULATORS |
| EP2797915B1 (en) | 2011-12-27 | 2016-07-13 | Ironwood Pharmaceuticals, Inc. | 2-benzyl-3-(oxazole/thiazole)-5-(pyrimidin-2-yl)-1(H)-pyrazole derivatives as stimulators of the soluble guanylate cyclase (sGC) for the treatment of e.g. hypertension or heart failure |
| WO2013167669A1 (en) | 2012-05-10 | 2013-11-14 | Bayer Pharma Aktiengesellschaft | Antibodies capable of binding to the coagulation factor xi and/or its activated form factor xia and uses thereof |
| US9309235B2 (en) | 2012-09-18 | 2016-04-12 | Ironwood Pharmaceuticals, Inc. | SGC stimulators |
| CA2885645A1 (en) | 2012-09-19 | 2014-03-27 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| LT3660013T (en) | 2013-03-15 | 2022-04-11 | Cyclerion Therapeutics, Inc. | Sgc stimulators |
| MX2016007522A (en) | 2013-12-11 | 2017-12-15 | Ironwood Pharmaceuticals Inc | Sgc stimulators. |
| EP3094327A1 (en) | 2014-01-13 | 2016-11-23 | Ironwood Pharmaceuticals, Inc. | USE OF sGC STIMULATORS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS |
| US10844064B2 (en) | 2014-09-17 | 2020-11-24 | Cyclerion Therapeutics, Inc. | sGC stimulators |
| US20170291889A1 (en) | 2014-09-17 | 2017-10-12 | Ironwood Pharmaceuticals, Inc. | Pyrazole derivatives as sgc stimulators |
| WO2016044445A2 (en) | 2014-09-17 | 2016-03-24 | Ironwood Pharmaceuticals, Inc. | sGC STIMULATORS |
| CA3006764A1 (en) | 2015-12-14 | 2017-06-22 | Ironwood Pharmaceuticals, Inc. | Use of sgc stimulators for the treatment of gastrointestinal sphincter dysfunction |
| US10889577B2 (en) | 2016-07-07 | 2021-01-12 | Cyclerion Therapeutics, Inc. | Solid forms of an sGC stimulator |
| KR102513343B1 (en) | 2016-07-07 | 2023-03-22 | 사이클리온 테라퓨틱스, 인크. | Phosphorus prodrugs of sGC stimulators |
| WO2018045276A1 (en) | 2016-09-02 | 2018-03-08 | Ironwood Pharmaceuticals, Inc. | Fused bicyclic sgc stimulators |
| MA46752A (en) | 2016-11-08 | 2019-09-18 | Cyclerion Therapeutics Inc | TREATMENT OF CNS DISEASES USING GCS STIMULATORS |
| IL266372B2 (en) | 2016-11-08 | 2023-11-01 | Cyclerion Therapeutics Inc | Sgc stimulators |
| US20190381039A1 (en) | 2016-12-13 | 2019-12-19 | Cyclerion Therapeutics, Inc. | USE OF sGC STIMULATORS FOR THE TREATMENT OF ESOPHAGEAL MOTILITY DISORDERS |
| EP3727388A1 (en) | 2017-12-19 | 2020-10-28 | Cyclerion Therapeutics, Inc. | Sgc stimulators |
| MX2023004858A (en) | 2018-03-07 | 2023-11-24 | Cyclerion Therapeutics Inc | Crystalline forms of an sgc stimulator. |
| KR20250141845A (en) | 2018-07-11 | 2025-09-29 | 티센토 쎄라퓨틱스 인크. | USE OF sGC STIMULATORS FOR THE TREATMENT OF MITOCHONRIAL DISORDERS |
| MX2021005892A (en) | 2018-11-28 | 2021-06-23 | Topadur Pharma Ag | NOVEL ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE AND INHIBITORS OF PHOSPHODIESTERASE WITH DUAL MODE OF ACTION AND THEIR USES. |
| WO2021195403A1 (en) | 2020-03-26 | 2021-09-30 | Cyclerion Therapeutics, Inc. | Deuterated sgc stimulators |
| WO2021202546A1 (en) | 2020-03-31 | 2021-10-07 | Cyclerion Therapeutics, Inc. | Early drug interventions to reduce covid-19 related respiratory distress, need for ventilator assistance and death |
| US20240207265A1 (en) | 2021-04-20 | 2024-06-27 | Tisento Therapeutics Inc. | TREATMENT OF CNS DISEASES WITH sGC STIMULATORS |
| BR112023021851A2 (en) | 2021-04-20 | 2024-02-06 | Tisento Therapeutics Inc | SGC STIMULANTS |
| JP2025536343A (en) | 2022-10-18 | 2025-11-05 | ティセント セラピューティクス インコーポレーテッド | Pyrimidine SGC stimulators |
| WO2024086182A1 (en) | 2022-10-18 | 2024-04-25 | Tisento Therapeutics Inc. | Treatment of mitochondrial diseases with sgc stimulators |
| CN118772140A (en) * | 2023-04-07 | 2024-10-15 | 四川大学 | A class of compounds and their use in treating hDHODH-mediated diseases |
-
1999
- 1999-09-08 DE DE19942809A patent/DE19942809A1/en not_active Withdrawn
-
2000
- 2000-08-28 WO PCT/EP2000/008362 patent/WO2001017998A2/en not_active Ceased
- 2000-08-28 AU AU74143/00A patent/AU7414300A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001017998A2 (en) | 2001-03-15 |
| WO2001017998A3 (en) | 2001-10-11 |
| DE19942809A1 (en) | 2001-03-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |