ATE67200T1 - Heterocyclische verbindungen. - Google Patents

Heterocyclische verbindungen.

Info

Publication number: ATE67200T1
Authority: AT; Austria
Prior art keywords: phenyl; lower alkyl; alkyl; alkoxy; formula
Prior art date: 1987-12-24

Application number

AT88311802T

Other languages

English (en)

Inventor

Terence James Ward

Janet Christine White

Original Assignee

Wyeth John & Brother Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-12-24

Filing date

1988-12-14

Publication date

1991-09-15

1987-12-24 Priority claimed from GB878730193A external-priority patent/GB8730193D0/en

1988-08-19 Priority claimed from GB888819728A external-priority patent/GB8819728D0/en

1988-12-14 Application filed by Wyeth John & Brother Ltd filed Critical Wyeth John & Brother Ltd

1991-09-15 Application granted granted Critical

1991-09-15 Publication of ATE67200T1 publication Critical patent/ATE67200T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/04—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C07D453/04—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Otolaryngology (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT88311802T 1987-12-24 1988-12-14 Heterocyclische verbindungen. ATE67200T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB878730193A GB8730193D0 (en)	1987-12-24	1987-12-24	Heterocyclic compounds
GB888819728A GB8819728D0 (en)	1988-08-19	1988-08-19	Heterocyclic compounds
EP88311802A EP0323077B1 (de)	1987-12-24	1988-12-14	Heterocyclische Verbindungen

Publications (1)

Publication Number	Publication Date
ATE67200T1 true ATE67200T1 (de)	1991-09-15

Family

ID=26293248

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT88311802T ATE67200T1 (de)	1987-12-24	1988-12-14	Heterocyclische verbindungen.
AT89202801T ATE107304T1 (de)	1987-12-24	1988-12-14	Heterocyclische verbindungen.

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT89202801T ATE107304T1 (de)	1987-12-24	1988-12-14	Heterocyclische verbindungen.

Country Status (18)

Country	Link
US (2)	US4983600A (de)
EP (2)	EP0323077B1 (de)
JP (1)	JP2588265B2 (de)
KR (1)	KR970009588B1 (de)
AT (2)	ATE67200T1 (de)
AU (1)	AU611976B2 (de)
CA (1)	CA1334095C (de)
DE (2)	DE3850255T2 (de)
DK (2)	DK710488A (de)
ES (2)	ES2053959T3 (de)
FI (1)	FI95031C (de)
GB (1)	GB2213816B (de)
GR (1)	GR3002701T3 (de)
HU (1)	HU204267B (de)
IE (2)	IE63474B1 (de)
IL (1)	IL88644A (de)
PH (1)	PH27437A (de)
PT (1)	PT89286B (de)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK443489D0 (da) *	1989-09-08	1989-09-08	Ferrosan As	Substituerede urinstofforbindelser, deres fremstilling og anvendelse
GB8922622D0 (en) *	1989-10-07	1989-11-22	Wyeth John & Brother Ltd	Aroylureas
GB2236751B (en)	1989-10-14	1993-04-28	Wyeth John & Brother Ltd	Heterocyclic compounds
DK40890D0 (da) *	1990-02-16	1990-02-16	Ferrosan As	Substituerede urinstofforbindelser, deres fremstilling og anvendelse
DE4009565A1 (de) *	1990-03-24	1991-09-26	Merck Patent Gmbh	Indolderivate
GB9106571D0 (en) *	1991-03-27	1991-05-15	Erba Carlo Spa	Derivatives of substituted imidazol-2-one and process for their preparation
US5140023A (en) *	1990-04-27	1992-08-18	G. D. Searle & Co.	Azatetracycle compounds
US5223613A (en) *	1990-04-27	1993-06-29	G. D. Searle & Co.	Azatetracycle compounds and process of preparing same
JP3122671B2 (ja) *	1990-05-23	2001-01-09	協和醗酵工業株式会社	複素環式化合物
ES2080482T3 (es) *	1990-12-28	1996-02-01	Kyowa Hakko Kogyo Kk	Derivado de quinoleina.
ES2065175T3 (es) *	1991-03-01	1995-02-01	Pfizer	Derivados de 1-azabiciclo(3.2.2)nonan-3-amina.
US5234921A (en) *	1991-03-07	1993-08-10	G. D. Searle & Co.	Meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof as pharmaceuticals
WO1992015590A1 (en) *	1991-03-07	1992-09-17	G.D. Searle & Co.	New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents
US5219850A (en) *	1991-03-07	1993-06-15	G. D. Searle & Co.	Pharmaceutically useful meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof
US5137893A (en) *	1991-03-07	1992-08-11	G. D. Searle & Co.	Pharmaceutically useful meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof
US5196547A (en) *	1991-03-07	1993-03-23	G. D. Searle & Co.	Meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof
US5227377A (en) *	1991-03-07	1993-07-13	G. D. Searle & Co.	Meso-azacyclic amides of certain bicyclic carboxylic acids
US5260303A (en) *	1991-03-07	1993-11-09	G. D. Searle & Co.	Imidazopyridines as serotonergic 5-HT3 antagonists
US5516782A (en) *	1991-03-07	1996-05-14	G. D. Searle & Co.	New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents
GB9121835D0 (en) *	1991-10-15	1991-11-27	Smithkline Beecham Plc	Pharmaceuticals
JPH05310732A (ja) *	1992-03-12	1993-11-22	Mitsubishi Kasei Corp	シンノリン−３−カルボン酸誘導体
US5244907A (en) *	1992-03-26	1993-09-14	A. H. Robins Company, Incorporated	Carbocyclic carboxylic acid amides and esters of azabicyclic compounds as gastric prokinetic, antiemetic, anxiolytic and antiarrhythmic agents
US5190953A (en) *	1992-03-26	1993-03-02	A. H. Robins Company, Incorporated	Heterocyclic carboxylic acid amides and esters of azabicyclic compounds as gastric prokinetic, antiemetic, anxiolytic and antiarrhythmic agents
EP0640081B1 (de) *	1992-03-31	2000-01-12	Glaxo Group Limited	Substituierte phenylcarbamate und phenylharnstoffe, ihre herstellung und ihre verwendung als 5-ht4-antagonisten
GB9206989D0 (en) *	1992-03-31	1992-05-13	Glaxo Group Ltd	Chemical compounds
GB9217629D0 (en) *	1992-08-19	1992-09-30	Wyeth John & Brother Ltd	Aroylureas
GB2269747B (en) *	1992-08-19	1996-06-05	Wyeth John & Brother Ltd	Aroyl-ureas as pharmaceuticals, particularly 5-ht3 antagonists
GB9224144D0 (en) *	1992-11-18	1993-01-06	Erba Carlo Spa	Phenyl-imidazolidinone derivatives and process for their preparation
GB9314174D0 (en) *	1993-07-08	1993-08-18	American Home Prod	5-ht3-antagonists
US6113877A (en) *	1996-03-20	2000-09-05	Wake Forest University	σ-2 receptors as biomarkers of tumor cell proliferation
US6676925B1 (en) *	1996-03-20	2004-01-13	Wake Forest University	Sigma-2 receptors as biomarkers of tumor cell proliferation
SE510305C2 (sv) *	1997-05-30	1999-05-10	Astra Ab	Nytt salt
US6022884A (en)	1997-11-07	2000-02-08	Amgen Inc.	Substituted pyridine compounds and methods of use
AU2001255734A1 (en)	2000-04-27	2001-11-07	Wake Forest University	Sigma-2 receptors as biomarkers of tumor cell proliferation
AU2001282873A1 (en)	2000-08-18	2002-03-04	Pharmacia And Upjohn Company	Quinuclidine-substituted aryl compounds for treatment of disease
US6492385B2 (en)	2000-08-18	2002-12-10	Pharmacia & Upjohn Company	Quinuclidine-substituted heteroaryl moieties for treatment of disease
US6479510B2 (en)	2000-08-18	2002-11-12	Pharmacia & Upjohn Company	Quinuclidine-substituted aryl compounds for treatment of disease
AU2001282875A1 (en)	2000-08-21	2002-03-04	Pharmacia And Upjohn Company	Quinuclidine-substituted heteroaryl moieties for treatment of disease
US6599916B2 (en)	2000-08-21	2003-07-29	Pharmacia & Upjohn Company	Quinuclidine-substituted heteroaryl moieties for treatment of disease
PE20021019A1 (es)	2001-04-19	2002-11-13	Upjohn Co	Grupos azabiciclicos sustituidos
AR036041A1 (es) *	2001-06-12	2004-08-04	Upjohn Co	Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen
AR036040A1 (es)	2001-06-12	2004-08-04	Upjohn Co	Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen
BR0212123A (pt) *	2001-08-24	2004-07-20	Upjohn Co	7-aza[2.2.1]biciclo-heptanos substituìdos com arila para o tratamento de doenças
JP2005504058A (ja)	2001-08-24	2005-02-10	ファルマシアアンドアップジョンカンパニーリミティドライアビリティーカンパニー	疾患の治療のための置換ヘテロアリール−７−アザ［２．２．１］ビシクロヘプタン
WO2003022856A1 (en) *	2001-09-12	2003-03-20	Pharmacia & Upjohn Company	Substituted 7-aza[2.2.1] bicycloheptanes for the treatment of diseases
ATE551340T1 (de)	2001-10-02	2012-04-15	Pharmacia & Upjohn Co Llc	Azabicyclisch- substituierte annelierte heteroaryl-verbinungen für die behandlung von krankheiten
US6849620B2 (en)	2001-10-26	2005-02-01	Pfizer Inc	N-(azabicyclo moieties)-substituted hetero-bicyclic aromatic compounds for the treatment of disease
EP1438308A1 (de) *	2001-10-26	2004-07-21	PHARMACIA & UPJOHN COMPANY	N-azabicyclosubstituierte heterobicyclische carbonsäureamide als nachr-agonisten
US6919359B2 (en) *	2001-11-08	2005-07-19	Pfizer Inc	Azabicyclic-substituted-heteroaryl compounds for the treatment of disease
EP1442037A1 (de)	2001-11-09	2004-08-04	PHARMACIA & UPJOHN COMPANY	Azabizyklo-phenyl-kondensierte-heterozyklische verbindungen und deren verwendung als alpha7 nachr liganden
JP2005522456A (ja)	2002-02-15	2005-07-28	ファルマシア・アンド・アップジョン・カンパニー・エルエルシー	Ｃｎｓ関連障害治療のためのアザビシクロ置換ベンゾイルアミドおよびチオアミド
AU2003219690A1 (en) *	2002-02-19	2003-09-09	Pharmacia And Upjohn Company	Fused bicyclic-n-bridged-heteroaromatic carboxamides for the treatment of disease
JP2005523287A (ja) *	2002-02-19	2005-08-04	ファルマシア・アンド・アップジョン・カンパニー・エルエルシー	疾患治療用アザビシクロ化合物
WO2003072578A1 (en) *	2002-02-20	2003-09-04	Pharmacia & Upjohn Company	Azabicyclic compounds with alfa7 nicotinic acetylcholine receptor activity
AU2003253686A1 (en) *	2002-08-01	2004-02-23	Pharmacia & Upjohn Company Llc	1h-pyrazole and 1h-pyrrole-azabicyclic compounds with alfa-7 nachr activity
JP2006506395A (ja) *	2002-11-01	2006-02-23	ファルマシア・アンド・アップジョン・カンパニー・エルエルシー	ＣＮＳ疾患の治療のための、α７ニコチンアゴニスト活性及び５ＨＴ３アンタゴニスト活性を有する化合物
US20070155780A1 (en) *	2004-04-15	2007-07-05	Hitoshi Nakata	Stabilized composition containing 4-amino-5-chloro-n-[(1r, 3r, 5s)-8-methyl-8-azabicyclo[3.2.1]oct-3-y1]-2-[1-methylbut-2-ynyloxy]benzamide
LT2685986T (lt)	2011-03-18	2020-03-10	Genzyme Corporation	Gliukozilceramido sintazės slopiklis
JOP20130273B1 (ar)	2012-09-11	2021-08-17	Genzyme Corp	مثبطات انزيم (سينثاز) غلوكوسيل سيراميد
ES3040555T3 (en)	2019-02-04	2025-11-03	Genzyme Corp	Treatment of ciliopathies using inhibitors of glucosylceramide synthase (gcs)
EP4100009A1 (de)	2020-02-03	2022-12-14	Genzyme Corporation	Verfahren zur behandlung neurologischer symptome im zusammenhang mit lysosomalen speicherkrankheiten
WO2022018695A1 (en)	2020-07-24	2022-01-27	Genzyme Corporation	Pharmaceutical compositions comprising venglustat

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4207327A (en) *	1977-08-19	1980-06-10	A. H. Robins Company, Inc.	N-(4-Pyrazolidinyl)benzamides and their amino precursors
EP0099194A3 (de) *	1982-07-03	1984-04-11	Beecham Group Plc	Benzamide
EP0158265A2 (de) *	1984-04-13	1985-10-16	Beecham Group Plc	Benzamid- und Anilid-Derivate
CA1260474A (en) *	1984-12-03	1989-09-26	Raymond A. Stokbroekx	Benzoxazol- and benzothiazolamine derivatives
GB8525913D0 (en) *	1985-10-21	1985-11-27	Beecham Group Plc	Compounds
DE3650772T2 (de) *	1985-04-27	2003-04-03	F. Hoffmann-La Roche Ag, Basel	Derivate von Indazole-3-carboxamide und -3-carboxylsäure
GB8520616D0 (en) *	1985-08-16	1985-09-25	Beecham Group Plc	Compounds
GB8525844D0 (en) *	1985-10-19	1985-11-20	Beecham Group Plc	Compounds
EP0235878A3 (de) *	1986-01-16	1989-06-14	Beecham Group Plc	Neue Verbindungen
DE3785507T2 (de) *	1986-07-31	1993-07-29	Beecham Group Plc	Azabicyclische verbindungen, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung.

1988
- 1988-12-08 AU AU26702/88A patent/AU611976B2/en not_active Ceased
- 1988-12-08 IE IE102988A patent/IE63474B1/en not_active IP Right Cessation
- 1988-12-08 IE IE366188A patent/IE62231B1/en not_active IP Right Cessation
- 1988-12-09 IL IL88644A patent/IL88644A/xx not_active IP Right Cessation
- 1988-12-09 CA CA000585519A patent/CA1334095C/en not_active Expired - Fee Related
- 1988-12-12 HU HU886399A patent/HU204267B/hu not_active IP Right Cessation
- 1988-12-14 AT AT88311802T patent/ATE67200T1/de not_active IP Right Cessation
- 1988-12-14 ES ES89202801T patent/ES2053959T3/es not_active Expired - Lifetime
- 1988-12-14 EP EP88311802A patent/EP0323077B1/de not_active Expired - Lifetime
- 1988-12-14 DE DE3850255T patent/DE3850255T2/de not_active Expired - Fee Related
- 1988-12-14 DE DE8888311802T patent/DE3864807D1/de not_active Expired - Fee Related
- 1988-12-14 EP EP89202801A patent/EP0361629B1/de not_active Expired - Lifetime
- 1988-12-14 AT AT89202801T patent/ATE107304T1/de not_active IP Right Cessation
- 1988-12-14 ES ES88311802T patent/ES2051867T3/es not_active Expired - Lifetime
- 1988-12-14 GB GB8829164A patent/GB2213816B/en not_active Expired - Fee Related
- 1988-12-20 DK DK710488A patent/DK710488A/da not_active Application Discontinuation
- 1988-12-21 PT PT89286A patent/PT89286B/pt not_active IP Right Cessation
- 1988-12-21 FI FI885917A patent/FI95031C/fi not_active IP Right Cessation
- 1988-12-22 KR KR1019880017218A patent/KR970009588B1/ko not_active Expired - Fee Related
- 1988-12-22 JP JP63324701A patent/JP2588265B2/ja not_active Expired - Fee Related
- 1988-12-23 PH PH37977A patent/PH27437A/en unknown
1989
- 1989-10-16 US US07/421,920 patent/US4983600A/en not_active Expired - Lifetime
- 1989-12-19 US US07/453,000 patent/US5106843A/en not_active Expired - Lifetime
1991
- 1991-09-12 GR GR91401252T patent/GR3002701T3/el unknown
1993
- 1993-07-08 DK DK93827A patent/DK82793D0/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
US4983600A (en)	1991-01-08
EP0361629B1 (de)	1994-06-15
IE883661L (en)	1989-05-24
US5106843A (en)	1992-04-21
DK82793A (da)	1993-07-08
IE881029L (en)	1989-06-24
ES2053959T3 (es)	1994-08-01
DE3850255T2 (de)	1994-09-22
IE62231B1 (en)	1995-01-11
IL88644A (en)	1993-05-13
DK710488A (da)	1989-06-25
HUT53101A (en)	1990-09-28
ATE107304T1 (de)	1994-07-15
DK82793D0 (da)	1993-07-08
DE3864807D1 (de)	1991-10-17
GB2213816B (en)	1991-05-08
CA1334095C (en)	1995-01-24
FI95031B (fi)	1995-08-31
KR970009588B1 (ko)	1997-06-14
FI885917A7 (fi)	1989-06-25
JPH01203365A (ja)	1989-08-16
EP0323077B1 (de)	1991-09-11
PT89286A (pt)	1989-12-29
KR890009923A (ko)	1989-08-04
GB2213816A (en)	1989-08-23
EP0361629A2 (de)	1990-04-04
PT89286B (pt)	1994-11-30
GB8829164D0 (en)	1989-01-25
IL88644A0 (en)	1989-07-31
AU611976B2 (en)	1991-06-27
ES2051867T3 (es)	1994-07-01
HU204267B (en)	1991-12-30
JP2588265B2 (ja)	1997-03-05
DK710488D0 (da)	1988-12-20
EP0323077A1 (de)	1989-07-05
AU2670288A (en)	1989-06-29
PH27437A (en)	1993-07-02
DE3850255D1 (de)	1994-07-21
FI95031C (fi)	1995-12-11
GR3002701T3 (en)	1993-01-25
EP0361629A3 (en)	1990-06-13
IE63474B1 (en)	1995-04-19

Publication	Publication Date	Title
ATE107304T1 (de)	1994-07-15	Heterocyclische verbindungen.
ATE542805T1 (de)	2012-02-15	Ppar-delta aktivatoren
EA200200446A1 (ru)	2002-12-26	НОВЫЕ α-АМИНОКИСЛОТНЫЕ СОЕДИНЕНИЯ, СПОСОБ ИХ ПОЛУЧЕНИЯ И ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ, ИХ СОДЕРЖАЩИЕ
ES2081563T3 (es)	1996-03-16	Benzamidas.
WO2000047580A3 (en)	2000-12-21	Phenyl urea and phenyl thiourea derivatives
ES2127718T3 (es)	1999-05-01	Derivados de amina.
TR200100852T2 (tr)	2001-10-22	2-Fenilpiran-4-on türevleri
DK394189A (da)	1990-02-13	Arylalkylaminer og -amider med antikonvulsive og neurobeskyttende egenskaber
ATE84028T1 (de)	1993-01-15	Biologisch aktive verbindungen.
ES8303303A1 (es)	1983-02-01	"un procedimiento para preparar derivados de urea y tiourea".
DK233788A (da)	1988-11-02	Herbicid
FR2224447A1 (en)	1974-10-31	N-(substd alkyl)-2-alk(enyl)oxybenzamides - antiemetics digestion-regulators and psychotropics
DE69216015D1 (de)	1997-01-30	Heterocyclische Alkoxyacrylsäurederivate mit fungizider Aktivität
FR2191893A1 (en)	1974-02-08	N'-Substd dihydro benzotriazepine diones - analgesics, antiinflammatories, anticonvulsants, hypnosedatives and tranquillisers
FR2355498A1 (fr)	1978-01-20	Composes 1,3-diazacycliques substitues en position 2, leur preparation et leurs utilisations therapeutiques
ES8800930A1 (es)	1987-12-01	Un metodo de preparacion de un compuesto de oxodiazina
FR2257581A1 (en)	1975-08-08	Herbicidal thiadiazolyl imidazolidinones - 1-(2-alkyl-(1,3,4)thiadiazol-5-yl)-3-(halo)alkylimidazolidine-2-o- nes
IE34651L (en)	1971-04-28	Heterocyclic compounds.
IT1056077B (it)	1982-01-30	Diazolidine tiadiazol sostituite e composizioni diserbantiche le contengono
NL7317578A (en)	1975-06-24	Herbicidal thiadiazolyl imidazolidinones - 1-(2-alkyl-(1,3,4)thiadiazol-5-yl)-3-(halo)alkylimidazolidine-2-o- nes
HUT50564A (en)	1990-03-28	Animal keeping pig-pen particularly for dropping swine and after-breeding of piglets
SE8703060D0 (sv)	1987-08-05	Para-klor-n-(3-morfolinopropyl)bensamid, hydroklorid av densamma, forfarande for framstellning av desamma och lekemedelspreparat med antidepressiv och psykostimulerande verkan innehallande (para-klor-n-(3-morfolinopropy
ES8501729A1 (es)	1984-12-01	Un metodo de preparar fenoxialcanodionas sustituidas.
ES8707500A1 (es)	1987-08-16	Procedimiento para la obtencion de isocianatos piperidinicos.

Legal Events

Date	Code	Title	Description
1992-04-15	UEP	Publication of translation of european patent specification
2006-09-15	REN	Ceased due to non-payment of the annual fee