ATE519744T1 - 1h-pyrazol-4-carbonsäure-amide, deren herstellung und verwendung als 11-beta-hydroxysteroid- dehydrogenase-hemmer - Google Patents
1h-pyrazol-4-carbonsäure-amide, deren herstellung und verwendung als 11-beta-hydroxysteroid- dehydrogenase-hemmerInfo
- Publication number
- ATE519744T1 ATE519744T1 AT06725326T AT06725326T ATE519744T1 AT E519744 T1 ATE519744 T1 AT E519744T1 AT 06725326 T AT06725326 T AT 06725326T AT 06725326 T AT06725326 T AT 06725326T AT E519744 T1 ATE519744 T1 AT E519744T1
- Authority
- AT
- Austria
- Prior art keywords
- pyrazole
- beta
- preparation
- carbonic acid
- acid amides
- Prior art date
Links
- 102000004277 11-beta-hydroxysteroid dehydrogenases Human genes 0.000 title 1
- 108090000874 11-beta-hydroxysteroid dehydrogenases Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66836705P | 2005-04-05 | 2005-04-05 | |
| PCT/EP2006/061057 WO2006106052A1 (en) | 2005-04-05 | 2006-03-27 | Pyrazoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE519744T1 true ATE519744T1 (de) | 2011-08-15 |
Family
ID=36514279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06725326T ATE519744T1 (de) | 2005-04-05 | 2006-03-27 | 1h-pyrazol-4-carbonsäure-amide, deren herstellung und verwendung als 11-beta-hydroxysteroid- dehydrogenase-hemmer |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US7345058B2 (de) |
| EP (1) | EP1928840B1 (de) |
| JP (1) | JP4880671B2 (de) |
| KR (1) | KR100931411B1 (de) |
| CN (1) | CN101155783B (de) |
| AR (1) | AR053203A1 (de) |
| AT (1) | ATE519744T1 (de) |
| AU (1) | AU2006232660B2 (de) |
| BR (1) | BRPI0610459A2 (de) |
| CA (1) | CA2602781C (de) |
| DK (1) | DK1928840T3 (de) |
| ES (1) | ES2369389T3 (de) |
| IL (1) | IL186118A0 (de) |
| MX (1) | MX2007012212A (de) |
| NO (1) | NO20074872L (de) |
| PL (1) | PL1928840T3 (de) |
| PT (1) | PT1928840E (de) |
| RU (1) | RU2381217C2 (de) |
| TW (1) | TWI309645B (de) |
| WO (1) | WO2006106052A1 (de) |
| ZA (1) | ZA200708419B (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101024227B1 (ko) * | 2005-11-21 | 2011-03-29 | 시오노기세이야쿠가부시키가이샤 | 11-β-히드록시스테로이드 탈수소효소 제 Ⅰ 형에 대한저해 활성을 갖는 헤테로시클릭 화합물 |
| HUE026011T2 (en) * | 2006-03-22 | 2016-05-30 | Hoffmann La Roche | Pyrazoles as 11-beta-HSD-1 |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| AU2007275301A1 (en) * | 2006-07-20 | 2008-01-24 | Amgen Inc. | Substituted azole aromatic heterocycles as inhibitors of 11-beta-HSD-1 |
| TW200827346A (en) * | 2006-11-03 | 2008-07-01 | Astrazeneca Ab | Chemical compounds |
| TW200836719A (en) | 2007-02-12 | 2008-09-16 | Astrazeneca Ab | Chemical compounds |
| AU2008233662B2 (en) * | 2007-04-02 | 2012-08-23 | Msd K.K. | Indoledione derivative |
| CN103288738B (zh) * | 2007-05-18 | 2016-03-16 | 盐野义制药株式会社 | 具有11β-羟基类固醇脱氢酶I型抑制活性的含氮杂环衍生物 |
| RU2440989C2 (ru) | 2007-07-17 | 2012-01-27 | Ф.Хоффманн-Ля Рош Аг | ИНГИБИТОРЫ 11β-ГИДРОКСИСТЕРОИДНОЙ ДЕГИДРОГЕНАЗЫ |
| FR2924931B1 (fr) * | 2007-12-12 | 2010-01-15 | Oreal | Utilisations de derives 1-°(1h-pyrazol-4-y!heterocycliques pour stimuler ou induire la pousse des fibres keratiniques et/ou freiner leur chute ; nouveaux composes ; compositions les contenant. |
| EP2244705A1 (de) * | 2008-02-04 | 2010-11-03 | AstraZeneca AB | Neue kristalline formen von 4- [4- (2-adamantylcarbamoyl) -5-tert-butyl-pyrazol-1-yl]benzoesäure |
| WO2010087770A1 (en) * | 2009-01-30 | 2010-08-05 | Astrazeneca Ab | Novel process for preparing carboxy-containing pyrazoleamido compounds 597 |
| UY33001A (es) * | 2009-11-06 | 2011-05-31 | Boehringer Ingelheim Int | Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina |
| BR112014031785A2 (pt) | 2012-06-20 | 2017-06-27 | Hoffmann La Roche | composto, composição farmacêutica, utilização do composto, método para o tratamento do câncer e invenção |
| EP4219494A1 (de) * | 2013-11-25 | 2023-08-02 | Corcept Therapeutics Incorporated | Octahydrokondensierte azadekalin-glucocorticoid-rezeptor-modulatoren |
| US9273254B2 (en) * | 2013-12-20 | 2016-03-01 | Ecolab Usa Inc. | Amino acetals and ketals as hydrogen sulfide and mercaptan scavengers |
| CN103772282B (zh) * | 2014-02-26 | 2015-09-23 | 上海毕得医药科技有限公司 | 一种3-叔丁基-1h-吡唑-4-甲醛的制备方法 |
| US11234971B2 (en) | 2018-12-19 | 2022-02-01 | Corcept Therapeutics Incorporated | Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent |
| US11389432B2 (en) | 2018-12-19 | 2022-07-19 | Corcept Therapeutics Incorporated | Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent |
| CA3121193C (en) | 2018-12-19 | 2024-03-12 | Corcept Therapeutics Incorporated | Pharmaceutical formulations containing relacorilant, a heteroaryl-ketone fused azadecalin compound |
| WO2020172501A1 (en) | 2019-02-22 | 2020-08-27 | Corcept Therapeutics Incorporated | Therapeutic uses of relacorilant, a heteroaryl-ketone fused azadecalin glucocorticoid receptor modulator |
| JP7569492B2 (ja) | 2019-12-11 | 2024-10-18 | コーセプト セラピューティクス， インコーポレイテッド | 抗精神病薬誘発性体重増加のミリコリラントによる治療方法 |
| CA3178767A1 (en) * | 2020-05-27 | 2021-12-02 | Hazel Hunt | Concomitant administration of glucocorticoid receptor modulator relacorilant and cyp2c8 substrates |
| CN114560811B (zh) * | 2022-03-11 | 2023-09-01 | 上海立森印迹医药技术有限公司 | 1,3,5-三取代-吡唑-4羧酸衍生物及其制备方法和应用 |
| EP4608402A1 (de) | 2022-10-28 | 2025-09-03 | Corcept Therapeutics Incorporated | Behandlung von amyotropher lateralsklerose mit dazucorilant |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATA210876A (de) * | 1975-03-25 | 1979-01-15 | Byk Gulden Lomberg Chem Fab | Verfahren zur herstellung von neuen nidrofuryl- pyrazolderivaten |
| US4620865A (en) | 1983-11-07 | 1986-11-04 | Eli Lilly And Company | Herbicidal and algicidal 1,5-disubstituted-1H-pyrazole-4-carboxamides |
| JPH0768220B2 (ja) * | 1986-04-24 | 1995-07-26 | 三井東圧化学株式会社 | 新規ピラゾ−ル誘導体、その製造法およびそれらを含有する農園芸用殺菌剤 |
| US4792565A (en) * | 1986-04-24 | 1988-12-20 | Mitsui Toatsu Chemicals, Inc. | Pyrazolecarbonylamine derivatives and agricultural and horticultural fungicides containing said compounds |
| IL91418A (en) * | 1988-09-01 | 1997-11-20 | Rhone Poulenc Agrochimie | (hetero) cyclic amide derivatives, process for their preparation and fungicidal compositions containing them |
| MY138097A (en) | 2000-03-22 | 2009-04-30 | Du Pont | Insecticidal anthranilamides |
| SE0001899D0 (sv) | 2000-05-22 | 2000-05-22 | Pharmacia & Upjohn Ab | New compounds |
| JP2002003410A (ja) | 2000-06-27 | 2002-01-09 | Fuji Photo Film Co Ltd | 芳香族ハロゲン化物の製造方法。 |
| WO2002044133A1 (en) | 2000-11-28 | 2002-06-06 | Pfizer Products Inc. | Preparation of sodium-hydrogen exchanger type-1 inhibitors |
| GB0107383D0 (en) | 2001-03-23 | 2001-05-16 | Univ Edinburgh | Lipid profile modulation |
| CA2466733A1 (en) | 2001-11-22 | 2003-05-30 | Meredith Williams | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 |
| WO2003043999A1 (en) | 2001-11-22 | 2003-05-30 | Biovitrum Ab | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 |
| WO2003044000A1 (en) | 2001-11-22 | 2003-05-30 | Biovitrum Ab | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 |
| JP2005511787A (ja) | 2001-12-19 | 2005-04-28 | ファイザー・プロダクツ・インク | ナトリウム−水素交換１型阻害物質を調製する方法 |
| US20030148987A1 (en) | 2001-12-21 | 2003-08-07 | Morris David J. | Selective 11beta-HSD inhibitors and methods of use thereof |
| EP1474139B1 (de) | 2002-02-01 | 2007-11-21 | Merck & Co., Inc. | 11-beta-hydroxysteroid-dehydrogenase-1-hemmer zur behandlung von diabetes, adipositas und dyslipidämie |
| WO2003075660A1 (en) | 2002-03-06 | 2003-09-18 | Merck & Co., Inc. | Method of treatment or prevention of obesity |
| AR040241A1 (es) | 2002-06-10 | 2005-03-23 | Merck & Co Inc | Inhibidores de la 11-beta-hidroxiesteroide deshidrogrenasa 1 para el tratamiento de la diabetes obesidad y dislipidemia |
| MXPA04012214A (es) * | 2002-06-13 | 2005-02-25 | Du Pont | Insecticidas de pirazolcarboxamida. |
| AU2003254481A1 (en) | 2002-07-27 | 2004-02-16 | Astrazeneca Ab | Chemical compounds |
| CA2501611A1 (en) | 2002-10-11 | 2004-04-22 | Astrazeneca Ab | 1,4-disubstituted piperidine derivatives and their use as 11-betahsd1 inhibitors |
| US20060058315A1 (en) | 2002-11-07 | 2006-03-16 | Astrazeneca Ab | 2-Oxo-ethanesulfonamide derivates |
| US20040122033A1 (en) | 2002-12-10 | 2004-06-24 | Nargund Ravi P. | Combination therapy for the treatment of obesity |
| JO2397B1 (en) | 2002-12-20 | 2007-06-17 | ميرك شارب اند دوم كوربوريشن | Terazol derivatives as beta-hydroxy steroid dihydrogenase-1 inhibitors |
| TW200503994A (en) | 2003-01-24 | 2005-02-01 | Novartis Ag | Organic compounds |
| ATE482747T1 (de) | 2003-04-11 | 2010-10-15 | High Point Pharmaceuticals Llc | Neue amide derivate und deren pharmazeutische verwendungen |
| JP2006522744A (ja) | 2003-04-11 | 2006-10-05 | ノボ ノルディスク アクティーゼルスカブ | グルココルチコイド受容体アゴニスト療法に伴う副作用を最小化するための、１１β−ヒドロキシステロイドデヒドロゲナーゼ１型阻害剤およびグルココルチコイド受容体アゴニストを使用する併用療法 |
| JP2006522750A (ja) | 2003-04-11 | 2006-10-05 | ノボ ノルディスク アクティーゼルスカブ | 代謝性症候群ならびに関連の疾患および障害を治療するために、１１β−ヒドロキシステロイドデヒドロゲナーゼ１型阻害剤および抗高血圧剤を使用する併用療法 |
| WO2004089471A2 (en) | 2003-04-11 | 2004-10-21 | Novo Nordisk A/S | NEW PYRAZOLO[1,5-a] PYRIMIDINES DERIVATIVES AND PHARMACEUTICAL USE THEREOF |
| WO2004103980A1 (en) | 2003-05-21 | 2004-12-02 | Biovitrum Ab | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type i |
| ATE476425T1 (de) | 2003-05-29 | 2010-08-15 | Merck Sharp & Dohme | Triazolderivate als inhibitoren von 11-beta- hydroxysteroid-dehydrogenase-1 |
| SE0301886D0 (sv) | 2003-06-25 | 2003-06-25 | Biovitrum Ab | New use V |
| SE0301883D0 (sv) | 2003-06-25 | 2003-06-25 | Biovitrum Ab | New use II |
| US7659408B2 (en) * | 2003-08-07 | 2010-02-09 | Merck Sharp & Dhome Corp. | Pyrazole carboxamides as inhibitors of 11-β-hydroxysteroid dehydrogenase-1 |
| EP1670460B1 (de) * | 2003-10-10 | 2014-11-26 | Bristol-Myers Squibb Company | Pyrazol-derivate als cannabinoid-rezeptor-modulatoren |
-
2006
- 2006-03-27 ES ES06725326T patent/ES2369389T3/es active Active
- 2006-03-27 KR KR1020077022649A patent/KR100931411B1/ko not_active Expired - Fee Related
- 2006-03-27 JP JP2008504736A patent/JP4880671B2/ja not_active Expired - Fee Related
- 2006-03-27 MX MX2007012212A patent/MX2007012212A/es active IP Right Grant
- 2006-03-27 AU AU2006232660A patent/AU2006232660B2/en not_active Ceased
- 2006-03-27 PT PT06725326T patent/PT1928840E/pt unknown
- 2006-03-27 DK DK06725326.0T patent/DK1928840T3/da active
- 2006-03-27 CA CA2602781A patent/CA2602781C/en not_active Expired - Fee Related
- 2006-03-27 PL PL06725326T patent/PL1928840T3/pl unknown
- 2006-03-27 EP EP06725326A patent/EP1928840B1/de not_active Not-in-force
- 2006-03-27 BR BRPI0610459-2A patent/BRPI0610459A2/pt not_active IP Right Cessation
- 2006-03-27 CN CN2006800111775A patent/CN101155783B/zh not_active Expired - Fee Related
- 2006-03-27 AT AT06725326T patent/ATE519744T1/de active
- 2006-03-27 WO PCT/EP2006/061057 patent/WO2006106052A1/en not_active Ceased
- 2006-03-27 RU RU2007140737/04A patent/RU2381217C2/ru not_active IP Right Cessation
- 2006-03-31 US US11/395,763 patent/US7345058B2/en not_active Expired - Fee Related
- 2006-04-03 TW TW095111719A patent/TWI309645B/zh not_active IP Right Cessation
- 2006-04-03 AR ARP060101312A patent/AR053203A1/es unknown
-
2007
- 2007-09-20 IL IL186118A patent/IL186118A0/en unknown
- 2007-09-25 NO NO20074872A patent/NO20074872L/no not_active Application Discontinuation
- 2007-10-02 ZA ZA200708419A patent/ZA200708419B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1928840A1 (de) | 2008-06-11 |
| WO2006106052A1 (en) | 2006-10-12 |
| AU2006232660B2 (en) | 2010-03-25 |
| US7345058B2 (en) | 2008-03-18 |
| CN101155783B (zh) | 2012-01-04 |
| CN101155783A (zh) | 2008-04-02 |
| IL186118A0 (en) | 2008-01-20 |
| ES2369389T3 (es) | 2011-11-30 |
| EP1928840B1 (de) | 2011-08-10 |
| KR20070108937A (ko) | 2007-11-13 |
| KR100931411B1 (ko) | 2009-12-10 |
| BRPI0610459A2 (pt) | 2010-06-22 |
| DK1928840T3 (da) | 2011-09-12 |
| US20060223852A1 (en) | 2006-10-05 |
| ZA200708419B (en) | 2008-11-26 |
| CA2602781A1 (en) | 2006-10-12 |
| CA2602781C (en) | 2011-02-08 |
| JP4880671B2 (ja) | 2012-02-22 |
| RU2381217C2 (ru) | 2010-02-10 |
| PL1928840T3 (pl) | 2012-01-31 |
| JP2008534647A (ja) | 2008-08-28 |
| TWI309645B (en) | 2009-05-11 |
| AU2006232660A1 (en) | 2006-10-12 |
| TW200643013A (en) | 2006-12-16 |
| AR053203A1 (es) | 2007-04-25 |
| MX2007012212A (es) | 2007-12-07 |
| PT1928840E (pt) | 2011-10-03 |
| NO20074872L (no) | 2007-10-30 |
| RU2007140737A (ru) | 2009-05-20 |
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