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ATE214069T1 - Heterocyclische verbindungen und ihre herstellung und verwendung - Google Patents

Heterocyclische verbindungen und ihre herstellung und verwendung

Info

Publication number
ATE214069T1
ATE214069T1 AT95909651T AT95909651T ATE214069T1 AT E214069 T1 ATE214069 T1 AT E214069T1 AT 95909651 T AT95909651 T AT 95909651T AT 95909651 T AT95909651 T AT 95909651T AT E214069 T1 ATE214069 T1 AT E214069T1
Authority
AT
Austria
Prior art keywords
independently
image
alkoxy
optionally substituted
alkyl
Prior art date
Application number
AT95909651T
Other languages
English (en)
Inventor
Lone Jeppesen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE214069T1 publication Critical patent/ATE214069T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT95909651T 1994-02-11 1995-01-30 Heterocyclische verbindungen und ihre herstellung und verwendung ATE214069T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK18394 1994-02-11
DK135194 1994-11-25
PCT/DK1995/000044 WO1995021842A1 (en) 1994-02-11 1995-01-30 Heterocyclic compounds and their preparation and use

Publications (1)

Publication Number Publication Date
ATE214069T1 true ATE214069T1 (de) 2002-03-15

Family

ID=26063483

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95909651T ATE214069T1 (de) 1994-02-11 1995-01-30 Heterocyclische verbindungen und ihre herstellung und verwendung

Country Status (15)

Country Link
US (1) US5741785A (de)
EP (1) EP0743945B1 (de)
JP (1) JPH09508632A (de)
KR (1) KR970701192A (de)
CN (1) CN1045964C (de)
AT (1) ATE214069T1 (de)
AU (1) AU692524B2 (de)
CA (1) CA2182957A1 (de)
DE (1) DE69525738D1 (de)
FI (1) FI963130L (de)
HU (1) HUT76323A (de)
IL (1) IL112588A (de)
NO (1) NO306781B1 (de)
NZ (1) NZ281183A (de)
WO (1) WO1995021842A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10513435A (ja) * 1994-09-30 1998-12-22 ビーエーエスエフ アクチェンゲゼルシャフト 複素環で置換された新規イミダゾロキノキサリノン、その製造および使用
FR2743363A1 (fr) * 1996-01-10 1997-07-11 Rhone Poulenc Rorer Sa 5h,10h-imidazo(1,2-a)indeno(1,2-e)pyrazine-a-ones substituees en position 2, leur preparation et les medicaments les contenant
DE19611476A1 (de) * 1996-03-22 1997-09-25 Basf Ag Neue heterocyclische substituierte Imidazolo-chinoxalinone, ihre Herstellung und Verwendung
IL125950A0 (en) * 1997-09-05 1999-04-11 Pfizer Prod Inc Methods of administering ampa receptor antagonists to treat dyskinesias associated with dopamine agonist therapy
ES2599054T3 (es) * 2006-12-13 2017-01-31 Aska Pharmaceutical Co., Ltd. Derivados de quinoxalina
EP2114948B1 (de) * 2006-12-28 2014-06-25 AbbVie Inc. Inhibitoren von poly(adp-ribose)polymerase
EP4403185A4 (de) 2021-09-15 2025-10-08 Univ Of The Ryukyus Pharmazeutische zusammensetzung zur behandlung von kognitivem verfall oder zur behandlung von übergewicht oder adipositas
US20240398775A1 (en) 2021-09-15 2024-12-05 University Of The Ryukyus Pharmaceutical composition for use in treating cognitive decline or for use in treating overweight or obesity

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2448541A1 (fr) * 1979-02-09 1980-09-05 Roussel Uclaf Nouveaux derives de l'oxoimidazoquinoxaline et leurs sels, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
GB2043637B (en) * 1979-02-09 1983-03-16 Roussel Lab Ltd Heterotricyclic derivatives
GB2043064B (en) * 1979-02-09 1983-04-13 Roussel Lab Ltd Oximidazoquinoxaline derivatives
US5055465A (en) * 1989-05-31 1991-10-08 Berlex Laboratories, Inc. Imidazoquinoxalinones, their aza analogs and process for their preparation
US5153196A (en) * 1991-06-05 1992-10-06 Eli Lilly And Company Excitatory amino acid receptor antagonists and methods for the use thereof
US5182386A (en) * 1991-08-27 1993-01-26 Neurogen Corporation Certain imidazoquinoxalinones; a new class of gaba brain receptor ligands
WO1993020077A1 (fr) * 1992-04-03 1993-10-14 Yamanouchi Pharmaceutical Co., Ltd. Derive de quinoxalinone fondue et composition pharmaceutique le contenant
DE4329970A1 (de) * 1993-03-31 1994-10-06 Basf Ag Neue Imidazolo-chinoxalinone, ihre Hestellung und Verwendung
DE4310523A1 (de) * 1993-03-31 1994-10-06 Basf Ag Imidazolo-chinoxalinone zur Behandlung zentralnervöser Erkrankungen
EP0691970B1 (de) * 1993-03-31 1998-11-11 Basf Aktiengesellschaft Imidazolochinoxalinonderivate als eaa antagonisten

Also Published As

Publication number Publication date
KR970701192A (ko) 1997-03-17
FI963130A7 (fi) 1996-10-09
JPH09508632A (ja) 1997-09-02
CA2182957A1 (en) 1995-08-17
AU1805595A (en) 1995-08-29
US5741785A (en) 1998-04-21
CN1045964C (zh) 1999-10-27
HU9602203D0 (en) 1996-10-28
DE69525738D1 (de) 2002-04-11
FI963130L (fi) 1996-10-09
NZ281183A (en) 1998-05-27
NO963337D0 (no) 1996-08-09
NO306781B1 (no) 1999-12-20
WO1995021842A1 (en) 1995-08-17
AU692524B2 (en) 1998-06-11
NO963337L (no) 1996-10-11
IL112588A0 (en) 1995-05-26
CN1145071A (zh) 1997-03-12
IL112588A (en) 1999-07-14
EP0743945A1 (de) 1996-11-27
HUT76323A (en) 1997-08-28
EP0743945B1 (de) 2002-03-06
FI963130A0 (fi) 1996-08-09

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties