ATA551979A - Verfahren zur herstellung neuer 2'-hydroxy-2-(5 -isoxazolylmethyl)-6,7-benzomorphane und deren saeureadditonssalzen - Google Patents

Verfahren zur herstellung neuer 2'-hydroxy-2-(5 -isoxazolylmethyl)-6,7-benzomorphane und deren saeureadditonssalzen

Info

Publication number: ATA551979A
Authority: AT; Austria
Prior art keywords: additone; benzomorphanes; isoxazolylmethyl; hydroxy; salts
Prior art date: 1977-04-15

Application number

AT551979A

Other languages

English (en)

Other versions

AT360666B (de

Original Assignee

Boehringer Sohn Ingelheim

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-04-15

Filing date

1979-08-14

Publication date

1980-06-15

1979-08-14 Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim

1979-08-14 Priority to AT551979A priority Critical patent/AT360666B/de

1980-06-15 Publication of ATA551979A publication Critical patent/ATA551979A/de

1981-01-26 Application granted granted Critical

1981-01-26 Publication of AT360666B publication Critical patent/AT360666B/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Dermatology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
General Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)

AT551979A 1977-04-15 1979-08-14 Verfahren zur herstellung neuer 2'-hydroxy-2-(5 -isoxazolylmethyl)-6,7-benzomorphane und deren saeureadditonssalzen AT360666B (de)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
AT551979A AT360666B (de)	1977-04-15	1979-08-14	Verfahren zur herstellung neuer 2'-hydroxy-2-(5 -isoxazolylmethyl)-6,7-benzomorphane und deren saeureadditonssalzen

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE19772716687 DE2716687A1 (de)	1977-04-15	1977-04-15	2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
AT241978A AT358192B (de)	1977-04-15	1978-04-06	Verfahren zur herstellung neuer 2'-hydroxy-2-(5 -isoxazolylmethyl)-6,7-benzomorphane und deren saeureadditionssalzen
AT551979A AT360666B (de)	1977-04-15	1979-08-14	Verfahren zur herstellung neuer 2'-hydroxy-2-(5 -isoxazolylmethyl)-6,7-benzomorphane und deren saeureadditonssalzen

Publications (2)

Publication Number	Publication Date
ATA551979A true ATA551979A (de)	1980-06-15
AT360666B AT360666B (de)	1981-01-26

Family

ID=6006359

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
AT241978A AT358192B (de)	1977-04-15	1978-04-06	Verfahren zur herstellung neuer 2'-hydroxy-2-(5 -isoxazolylmethyl)-6,7-benzomorphane und deren saeureadditionssalzen
AT552079A AT360667B (de)	1977-04-15	1979-08-14	Verfahren zur herstellung neuer 2'-hydroxy-2-(5 -isoxazolylmethyl)-6,7-benzomorphane und deren saeureadditionssalzen
AT551979A AT360666B (de)	1977-04-15	1979-08-14	Verfahren zur herstellung neuer 2'-hydroxy-2-(5 -isoxazolylmethyl)-6,7-benzomorphane und deren saeureadditonssalzen

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
AT241978A AT358192B (de)	1977-04-15	1978-04-06	Verfahren zur herstellung neuer 2'-hydroxy-2-(5 -isoxazolylmethyl)-6,7-benzomorphane und deren saeureadditionssalzen
AT552079A AT360667B (de)	1977-04-15	1979-08-14	Verfahren zur herstellung neuer 2'-hydroxy-2-(5 -isoxazolylmethyl)-6,7-benzomorphane und deren saeureadditionssalzen

Country Status (25)

Country	Link
US (1)	US4133888A (de)
JP (1)	JPS53130671A (de)
AT (3)	AT358192B (de)
AU (1)	AU514938B2 (de)
BE (1)	BE866013A (de)
CA (1)	CA1079726A (de)
CH (1)	CH638519A5 (de)
DE (1)	DE2716687A1 (de)
DK (1)	DK144678C (de)
ES (3)	ES468798A1 (de)
FI (1)	FI63399C (de)
FR (1)	FR2387228A1 (de)
GB (1)	GB1575156A (de)
GR (1)	GR64819B (de)
IE (1)	IE46722B1 (de)
IL (1)	IL54509A (de)
IT (1)	IT1102595B (de)
LU (1)	LU79430A1 (de)
NL (1)	NL7803977A (de)
NO (1)	NO148418C (de)
NZ (1)	NZ186971A (de)
PH (1)	PH13854A (de)
PT (1)	PT67907B (de)
SE (1)	SE430160B (de)
ZA (1)	ZA782149B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1575009A (en) *	1976-06-21	1980-09-17	Acf Chemiefarma Nv	6,7-benzomorphan derivatives
NL7907800A (nl)	1979-10-23	1981-04-27	Acf Chemiefarma Nv	Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan, farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werkwijze voor het bereiden van deze verbindingen en de farmaceutische preparaten.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3499906A (en) *	1966-05-20	1970-03-10	Merck & Co Inc	5,9-diethyl-2'-hydroxy-2-substituted-6,7-benzomorphans
CS166803B2 (de) *	1971-02-08	1976-03-29	Boehringer Sohn Ingelheim
US3853889A (en) *	1973-07-18	1974-12-10	Bristol Myers Co	3,14-substituted-8-oxamorphinans
DE2411382C3 (de) *	1974-03-09	1979-09-06	C.H. Boehringer Sohn, 6507 Ingelheim	2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung
DE2437610A1 (de) *	1974-08-05	1976-02-26	Boehringer Sohn Ingelheim	Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung

1977
- 1977-04-15 DE DE19772716687 patent/DE2716687A1/de not_active Ceased
1978
- 1978-04-04 FI FI781025A patent/FI63399C/fi not_active IP Right Cessation
- 1978-04-06 AT AT241978A patent/AT358192B/de not_active IP Right Cessation
- 1978-04-06 GR GR55915A patent/GR64819B/el unknown
- 1978-04-12 US US05/895,631 patent/US4133888A/en not_active Expired - Lifetime
- 1978-04-12 CH CH394078A patent/CH638519A5/de not_active IP Right Cessation
- 1978-04-13 LU LU79430A patent/LU79430A1/de unknown
- 1978-04-13 IT IT48887/78A patent/IT1102595B/it active
- 1978-04-14 FR FR7811110A patent/FR2387228A1/fr active Granted
- 1978-04-14 ZA ZA00782149A patent/ZA782149B/xx unknown
- 1978-04-14 JP JP4409178A patent/JPS53130671A/ja active Pending
- 1978-04-14 IE IE742/78A patent/IE46722B1/en unknown
- 1978-04-14 AU AU35098/78A patent/AU514938B2/en not_active Expired
- 1978-04-14 NL NL7803977A patent/NL7803977A/xx not_active Application Discontinuation
- 1978-04-14 NO NO781310A patent/NO148418C/no unknown
- 1978-04-14 PT PT67907A patent/PT67907B/pt unknown
- 1978-04-14 GB GB14796/78A patent/GB1575156A/en not_active Expired
- 1978-04-14 SE SE7804260A patent/SE430160B/sv not_active IP Right Cessation
- 1978-04-14 IL IL54509A patent/IL54509A/xx unknown
- 1978-04-14 DK DK163578A patent/DK144678C/da not_active IP Right Cessation
- 1978-04-14 PH PH21010A patent/PH13854A/en unknown
- 1978-04-14 CA CA301,198A patent/CA1079726A/en not_active Expired
- 1978-04-14 BE BE186818A patent/BE866013A/xx not_active IP Right Cessation
- 1978-04-14 ES ES468798A patent/ES468798A1/es not_active Expired
- 1978-04-14 NZ NZ186971A patent/NZ186971A/xx unknown
- 1978-08-07 ES ES472407A patent/ES472407A1/es not_active Expired
- 1978-08-07 ES ES472408A patent/ES472408A1/es not_active Expired
1979
- 1979-08-14 AT AT552079A patent/AT360667B/de not_active IP Right Cessation
- 1979-08-14 AT AT551979A patent/AT360666B/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
IT7848887A0 (it)	1978-04-13
CH638519A5 (de)	1983-09-30
ATA552079A (de)	1980-06-15
AT358192B (de)	1980-08-25
IL54509A (en)	1982-04-30
DE2716687A1 (de)	1978-10-19
IE780742L (en)	1978-10-15
FI63399B (fi)	1983-02-28
US4133888A (en)	1979-01-09
LU79430A1 (de)	1979-05-25
JPS53130671A (en)	1978-11-14
NO781310L (no)	1978-10-17
ATA241978A (de)	1980-01-15
PT67907B (fr)	1980-06-16
NO148418C (no)	1983-10-05
ZA782149B (en)	1979-12-27
ES472408A1 (es)	1979-04-01
AT360667B (de)	1981-01-26
PT67907A (fr)	1978-05-01
AU514938B2 (en)	1981-03-05
GR64819B (en)	1980-06-03
FR2387228A1 (fr)	1978-11-10
CA1079726A (en)	1980-06-17
DK144678C (da)	1982-10-11
SE430160B (sv)	1983-10-24
DK163578A (da)	1978-10-16
FI63399C (fi)	1983-06-10
NL7803977A (nl)	1978-10-17
IL54509A0 (en)	1978-07-31
SE7804260L (sv)	1978-10-16
IT1102595B (it)	1985-10-07
AT360666B (de)	1981-01-26
ES472407A1 (es)	1979-04-01
NO148418B (no)	1983-06-27
DK144678B (da)	1982-05-10
AU3509878A (en)	1979-10-18
GB1575156A (en)	1980-09-17
PH13854A (en)	1980-10-22
ES468798A1 (es)	1978-12-01
FR2387228B1 (de)	1981-05-29
IE46722B1 (en)	1983-09-07
BE866013A (fr)	1978-10-16
NZ186971A (en)	1980-10-24
FI781025A7 (fi)	1978-10-16

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Legal Events

Date	Code	Title	Description
1988-03-15	ELJ	Ceased due to non-payment of the annual fee