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ATA388376A - Verfahren zur herstellung einer neuen kristallinen form von flunisolid - Google Patents

Verfahren zur herstellung einer neuen kristallinen form von flunisolid

Info

Publication number
ATA388376A
ATA388376A AT388376A AT388376A ATA388376A AT A388376 A ATA388376 A AT A388376A AT 388376 A AT388376 A AT 388376A AT 388376 A AT388376 A AT 388376A AT A388376 A ATA388376 A AT A388376A
Authority
AT
Austria
Prior art keywords
benzenesulphonamides
salts
novel
preparation
novel benzenesulphonamides
Prior art date
Application number
AT388376A
Other languages
English (en)
Other versions
AT357702B (de
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of ATA388376A publication Critical patent/ATA388376A/de
Application granted granted Critical
Publication of AT357702B publication Critical patent/AT357702B/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
AT388376A 1975-05-27 1976-05-26 Verfahren zur herstellung einer neuen kristallinen form von flunisolid AT357702B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58130175A 1975-05-27 1975-05-27
US58130075A 1975-05-27 1975-05-27

Publications (2)

Publication Number Publication Date
ATA388376A true ATA388376A (de) 1979-12-15
AT357702B AT357702B (de) 1980-07-25

Family

ID=27078279

Family Applications (1)

Application Number Title Priority Date Filing Date
AT388376A AT357702B (de) 1975-05-27 1976-05-26 Verfahren zur herstellung einer neuen kristallinen form von flunisolid

Country Status (15)

Country Link
JP (1) JPS51144719A (de)
AT (1) AT357702B (de)
AU (1) AU506080B2 (de)
CA (1) CA1075228A (de)
DE (2) DE2661037C2 (de)
ES (1) ES448220A1 (de)
FR (1) FR2361900A1 (de)
GB (1) GB1525181A (de)
HK (1) HK8580A (de)
IL (1) IL49652A (de)
MX (1) MX3864E (de)
MY (1) MY8000275A (de)
NL (1) NL191234C (de)
NZ (1) NZ180946A (de)
SE (1) SE421426B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH643567A5 (de) * 1979-05-21 1984-06-15 Syntex Corp Verfahren zur herstellung einer kristallinen form von flunisolid.
ATE3774T1 (de) * 1980-05-02 1983-06-15 Schering Corporation Beclomethason-ester-solvate, verfahren zu ihrer herstellung und herstellung einer formulierung.
GB2127689B (en) * 1982-10-05 1986-07-09 Sandoz Ltd Calcitonin inhalation compositions
US4782047A (en) * 1986-05-22 1988-11-01 Syntex Pharmaceuticals International Ltd. Aqueous steroid formulations for nasal administration
US5707634A (en) * 1988-10-05 1998-01-13 Pharmacia & Upjohn Company Finely divided solid crystalline powders via precipitation into an anti-solvent
JP2843857B2 (ja) * 1988-10-05 1999-01-06 ファルマシア・アンド・アップジョン・カンパニー 反溶剤への沈澱を介する微細分化固体結晶性粉末
DE4003272A1 (de) 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgasmischungen und ihre verwendung in arzneimittelzubereitungen
MX9800125A (es) * 1995-06-27 1998-03-31 Boehringer Ingelheim Kg Nuevas composiciones medicinales estables para generar aerosoles libres de gas propulsor.
DE19653969A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
US20010031244A1 (en) 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
DZ2947A1 (fr) 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
PL206121B1 (pl) * 1999-03-03 2010-07-30 Optinose Asoptinose As Nosowe urządzenie do dostarczania substancji do nosowej części dróg oddechowych pacjenta
IT1313553B1 (it) * 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
IT1317846B1 (it) 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
MXPA02011414A (es) 2000-05-22 2003-06-06 Chiesi Farma Spa Formulaciones farmaceuticas en solucion estable para inhaladores presurizados con medicion de dosis.
ES2222294T3 (es) 2001-07-02 2005-02-01 Chiesi Farmaceutici S.P.A. Formulacion optimizada de tobramicina para administracion en forma de aerosol.
JP5238779B2 (ja) * 2003-04-25 2013-07-17 ロート製薬株式会社 点鼻剤
JP4632687B2 (ja) * 2003-04-25 2011-02-16 ロート製薬株式会社 点鼻剤
EP1595531A1 (de) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stabile Arzneimittellösung für Druckdosierinhalatoren
CN105188758A (zh) * 2013-03-15 2015-12-23 梅迪奇斯医药公司 氟尼缩松的局部组合物及治疗方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126375A (en) * 1964-03-24 Chioacyl
BE585432A (fr) * 1958-12-08 1960-06-08 American Cyanamid Co Stéroïdes fluorés.
US3282791A (en) 1965-08-17 1966-11-01 Merck & Co Inc Inhalation aerosol suspension of anhydrous disodium dexamethasone phosphate, propellents, and sorbitan trioleate
US3592930A (en) 1968-07-19 1971-07-13 Syntex Corp Moisture-deterioratable topical medicaments,particularly anti-inflammatory steroids,in a substantially non-aqueous fatty alcohol-propylene glycol vehicle
DE2015300A1 (de) * 1969-04-01 1970-10-29 Syntex Corp., Panania;PM örtliche, entzündungshemmende Präparate und Verfahren zu ihrer Verwendung
GB1429184A (en) * 1972-04-20 1976-03-24 Allen & Hanburys Ltd Physically anti-inflammatory steroids for use in aerosols
DE2332663C2 (de) 1973-06-23 1986-07-31 Schering AG, 1000 Berlin und 4709 Bergkamen Verwendung von Kortikoid-Wirkstoffen zur Inhalationstherapie
US3934013A (en) * 1975-02-21 1976-01-20 Syntex (U.S.A.) Inc. Pharmaceutical composition

Also Published As

Publication number Publication date
AU1430176A (en) 1977-12-01
DE2624924A1 (de) 1977-12-15
FR2361900A1 (fr) 1978-03-17
GB1525181A (en) 1978-09-20
JPS6247880B2 (de) 1987-10-09
AT357702B (de) 1980-07-25
MY8000275A (en) 1980-12-31
SE7605927L (sv) 1976-11-28
SE421426B (sv) 1981-12-21
NL191234B (nl) 1994-11-01
NL191234C (nl) 1995-04-03
HK8580A (en) 1980-03-14
DE2661037C2 (de) 1989-04-06
NL7605699A (nl) 1976-11-30
FR2361900B1 (de) 1979-04-13
JPS51144719A (en) 1976-12-13
IL49652A0 (en) 1976-07-30
MX3864E (es) 1981-08-26
CA1075228A (en) 1980-04-08
AU506080B2 (en) 1979-12-13
NZ180946A (en) 1978-07-28
DE2624924C2 (de) 1986-11-27
ES448220A1 (es) 1977-11-01
IL49652A (en) 1979-05-31

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
ELA Expired due to lapse of time